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The map label for this gene is nuoC

Identifier: 99080584

GI number: 99080584

Start: 800625

End: 801230

Strand: Direct

Name: nuoC

Synonym: TM1040_0743

Alternate gene names: 99080584

Gene position: 800625-801230 (Clockwise)

Preceding gene: 99080583

Following gene: 99080585

Centisome position: 25.01

GC content: 59.41

Gene sequence:

>606_bases
ATGATCGAAGCATTGCAAGACCTTGGCCACCAGATTGAAGCCAAGCGCCCCGAGTGCGTATTGTCCTGGGATATTGCCCA
TGGCGAACTGAACATCGACGTAAAGCCCGCCAACATCGCGGGCCTCGTTGAATTCCTGCGCGTCGACAGCGCCTGCCGGT
TCTCCACGCTGGTGGACATTACCGCAGTGGACTATCCCGAGCGCACCAAGCGTTTTGACGTGGTGTATCACCTCCTTTCG
ATGTACCAGAACCAGCGCATCCGTCTGCGCGCAGCCGTGCGCGAAGAGGACATGGTGCCCTCCATCGTGGATGTGCACCC
CTCCGCCAACTGGTTCGAGCGCGAAGTCTTTGACATGTTCGGCATCCTGTTCACGGGGCACCCGGACCTGCGCCGCCTGC
TGACGGACTATGGCTTCCGCGGCCACCCGCTGCGCAAGGATTTCCCGACCACCGGTTACACCGAAGTGCGCTATGACGAG
GCGCAAAAGCGCGTGGTCTACGAGCCGGTGAAGCTGGTTCAGGAATACCGCCAGTTTGACTTCATGAGCCCTTGGGAAGG
TGCGGAATATATCCTGCCGGGTGACGAGAAAGAGATCGCGAAATGA

Upstream 100 bases:

>100_bases
CTGCCCGCCCACCGCAGAGGCGCTCCTTTATGGGCTGATGCAGCTGCAGCGCAAGATCCGCCGCACTGGCACCCTTGTGC
GCTAAGGGCAGGAGATTCAG

Downstream 100 bases:

>100_bases
TGAACCCTGATTTGTTTCTATTAGTGGGAGTTCTTCAGGTTCTGCTGGTGCTTTCGGCTATCGGTGGTCTGGGCTGGCTT
TGGGTGAAACTGGTTCGCTT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIEALQDLGHQIEAKRPECVLSWDIAHGELNIDVKPANIAGLVEFLRVDSACRFSTLVDITAVDYPERTKRFDVVYHLLS
MYQNQRIRLRAAVREEDMVPSIVDVHPSANWFEREVFDMFGILFTGHPDLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDE
AQKRVVYEPVKLVQEYRQFDFMSPWEGAEYILPGDEKEIAK

Sequences:

>Translated_201_residues
MIEALQDLGHQIEAKRPECVLSWDIAHGELNIDVKPANIAGLVEFLRVDSACRFSTLVDITAVDYPERTKRFDVVYHLLS
MYQNQRIRLRAAVREEDMVPSIVDVHPSANWFEREVFDMFGILFTGHPDLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDE
AQKRVVYEPVKLVQEYRQFDFMSPWEGAEYILPGDEKEIAK
>Mature_201_residues
MIEALQDLGHQIEAKRPECVLSWDIAHGELNIDVKPANIAGLVEFLRVDSACRFSTLVDITAVDYPERTKRFDVVYHLLS
MYQNQRIRLRAAVREEDMVPSIVDVHPSANWFEREVFDMFGILFTGHPDLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDE
AQKRVVYEPVKLVQEYRQFDFMSPWEGAEYILPGDEKEIAK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=160, Percent_Identity=53.125, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI145693162, Length=105, Percent_Identity=43.8095238095238, Blast_Score=95, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=45.4054054054054, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=45.4054054054054, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=46.9945355191257, Blast_Score=185, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_SILST (Q1GIP0)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612738.1
- ProteinModelPortal:   Q1GIP0
- SMR:   Q1GIP0
- STRING:   Q1GIP0
- GeneID:   4076113
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0743
- NMPDR:   fig|292414.1.peg.2846
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   SSP292414:TM1040_0743-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23483; Mature: 23483

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEALQDLGHQIEAKRPECVLSWDIAHGELNIDVKPANIAGLVEFLRVDSACRFSTLVDI
CCHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCHHHHHHHHHHHCCCCCHHHHEEE
TAVDYPERTKRFDVVYHLLSMYQNQRIRLRAAVREEDMVPSIVDVHPSANWFEREVFDMF
EECCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCEEECCCCCCHHHHHHHHHH
GILFTGHPDLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDEAQKRVVYEPVKLVQEYRQFD
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
FMSPWEGAEYILPGDEKEIAK
CCCCCCCCEEECCCCHHHHCC
>Mature Secondary Structure
MIEALQDLGHQIEAKRPECVLSWDIAHGELNIDVKPANIAGLVEFLRVDSACRFSTLVDI
CCHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCHHHHHHHHHHHCCCCCHHHHEEE
TAVDYPERTKRFDVVYHLLSMYQNQRIRLRAAVREEDMVPSIVDVHPSANWFEREVFDMF
EECCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCEEECCCCCCHHHHHHHHHH
GILFTGHPDLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDEAQKRVVYEPVKLVQEYRQFD
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
FMSPWEGAEYILPGDEKEIAK
CCCCCCCCEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA