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The map label for this gene is appC [H]

Identifier: 99080554

GI number: 99080554

Start: 767742

End: 768734

Strand: Reverse

Name: appC [H]

Synonym: TM1040_0713

Alternate gene names: 99080554

Gene position: 768734-767742 (Counterclockwise)

Preceding gene: 99080555

Following gene: 99080552

Centisome position: 24.02

GC content: 62.74

Gene sequence:

>993_bases
ATGACTGACGCTGCAAAAGAAAAGACCCTGCAGCACTCCAGCGTGCAGGACGAACTCGCCACACCCGCCCGCAGCCAGTG
GCGCGAGATCTGGGTTCAGTTCAAATCGCACCGAGGCGCATTGTTCGGGGGCTGCCTGTTCCTGTTCATCGTGCTGGGCG
TGGTGGTTGGCCCGTTCATCTACTGGAATGATGCCAAGTTCGTACCCACGGGCCGTGACTTCATCACGTTGCGGGACATG
CGTCCGATCTATCACGCGCTGTGGGACCCCTCGGCCAAGATGGACTGGGCCTATCCGCTCGGGACCGACAACCTTGGCCG
TGACACGTTGGCGCGTCTGATGTTTGGCGGTCGTGTGTCGCTTGCCGTGGGCATGGCGGCGATGATCCTCGCGCTGATCC
TCGGCAGCCTGATCGGGGTGCTGGCGGGCTACTTCAAAAAGCTCGACGGCCTCCTGATGCGGATGACTGATCTGTTTCTC
GCCCTGCCCCTCTTGCCGATGATCCTCGTCGCAGCGGTGTTGTTTCGCGAGAGCCTGTCGAAAACCATCGGCCCAGAAGG
CGGCATCTTTGTACTGATCGTCTGTCTGATCGGGATCACCTCCTGGATGCCGACCGCACGGATCGTGCGCGGCGACGTGC
TGGCGATCAAGGAACGCGAGTTCGTGCTGGCGGCCCGTTCCATCGGGACCAAGCCCGGCAATATCATCTCGCGTCACATC
CTGCCGAACGTGCTCTCGCCCATCATGGTGTCGGCCACCTTGGGGATCGCCACCGCGATCATCACCGAATCGGCGCTGTC
CTTCCTCGGCTTTGGCTTCCCGCCGGACTTCCCGACCTGGGGCCGCCTGCTGAATGATGCCGTGGACCGGATGACCCTCT
TCCCCGAGCGCGTGCTTTGGCCCGGCATCCTGATCTCGCTGACGGTTCTGTCGGTAAACTATCTGGGTGACGGTCTGCGC
GACGCGCTGGACCCGCGTATCCGGGGCCGCTGA

Upstream 100 bases:

>100_bases
CCTATGGTGCAGACGCTTACCTTCATCTTTGCCGTGCTCATCGTGCTGTTCAACCTGATCGCCGATGTGCTCTACGGCAT
TCTCGACCCGAGGATCCGCT

Downstream 100 bases:

>100_bases
AGCACCCTACACCCAAAAGAAAGGCCGCCCGGTGAGGCGGCCTTTTGCGTTTCTGGACTACTTGCTCGGCTTACGGCCCT
CGCGCCCGGTCAGTGCAGGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTDAAKEKTLQHSSVQDELATPARSQWREIWVQFKSHRGALFGGCLFLFIVLGVVVGPFIYWNDAKFVPTGRDFITLRDM
RPIYHALWDPSAKMDWAYPLGTDNLGRDTLARLMFGGRVSLAVGMAAMILALILGSLIGVLAGYFKKLDGLLMRMTDLFL
ALPLLPMILVAAVLFRESLSKTIGPEGGIFVLIVCLIGITSWMPTARIVRGDVLAIKEREFVLAARSIGTKPGNIISRHI
LPNVLSPIMVSATLGIATAIITESALSFLGFGFPPDFPTWGRLLNDAVDRMTLFPERVLWPGILISLTVLSVNYLGDGLR
DALDPRIRGR

Sequences:

>Translated_330_residues
MTDAAKEKTLQHSSVQDELATPARSQWREIWVQFKSHRGALFGGCLFLFIVLGVVVGPFIYWNDAKFVPTGRDFITLRDM
RPIYHALWDPSAKMDWAYPLGTDNLGRDTLARLMFGGRVSLAVGMAAMILALILGSLIGVLAGYFKKLDGLLMRMTDLFL
ALPLLPMILVAAVLFRESLSKTIGPEGGIFVLIVCLIGITSWMPTARIVRGDVLAIKEREFVLAARSIGTKPGNIISRHI
LPNVLSPIMVSATLGIATAIITESALSFLGFGFPPDFPTWGRLLNDAVDRMTLFPERVLWPGILISLTVLSVNYLGDGLR
DALDPRIRGR
>Mature_329_residues
TDAAKEKTLQHSSVQDELATPARSQWREIWVQFKSHRGALFGGCLFLFIVLGVVVGPFIYWNDAKFVPTGRDFITLRDMR
PIYHALWDPSAKMDWAYPLGTDNLGRDTLARLMFGGRVSLAVGMAAMILALILGSLIGVLAGYFKKLDGLLMRMTDLFLA
LPLLPMILVAAVLFRESLSKTIGPEGGIFVLIVCLIGITSWMPTARIVRGDVLAIKEREFVLAARSIGTKPGNIISRHIL
PNVLSPIMVSATLGIATAIITESALSFLGFGFPPDFPTWGRLLNDAVDRMTLFPERVLWPGILISLTVLSVNYLGDGLRD
ALDPRIRGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=308, Percent_Identity=37.012987012987, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1787498, Length=329, Percent_Identity=33.434650455927, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1789964, Length=309, Percent_Identity=36.8932038834951, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789889, Length=236, Percent_Identity=34.7457627118644, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787760, Length=242, Percent_Identity=30.9917355371901, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788505, Length=273, Percent_Identity=28.9377289377289, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787549, Length=322, Percent_Identity=29.8136645962733, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36309; Mature: 36177

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAKEKTLQHSSVQDELATPARSQWREIWVQFKSHRGALFGGCLFLFIVLGVVVGPFI
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEE
YWNDAKFVPTGRDFITLRDMRPIYHALWDPSAKMDWAYPLGTDNLGRDTLARLMFGGRVS
EECCCEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHH
LAVGMAAMILALILGSLIGVLAGYFKKLDGLLMRMTDLFLALPLLPMILVAAVLFRESLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTIGPEGGIFVLIVCLIGITSWMPTARIVRGDVLAIKEREFVLAARSIGTKPGNIISRHI
HHCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCEEECHHHHHHHHHCCCCCHHHHHHHH
LPNVLSPIMVSATLGIATAIITESALSFLGFGFPPDFPTWGRLLNDAVDRMTLFPERVLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHH
PGILISLTVLSVNYLGDGLRDALDPRIRGR
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TDAAKEKTLQHSSVQDELATPARSQWREIWVQFKSHRGALFGGCLFLFIVLGVVVGPFI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEE
YWNDAKFVPTGRDFITLRDMRPIYHALWDPSAKMDWAYPLGTDNLGRDTLARLMFGGRVS
EECCCEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHH
LAVGMAAMILALILGSLIGVLAGYFKKLDGLLMRMTDLFLALPLLPMILVAAVLFRESLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTIGPEGGIFVLIVCLIGITSWMPTARIVRGDVLAIKEREFVLAARSIGTKPGNIISRHI
HHCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCEEECHHHHHHHHHCCCCCHHHHHHHH
LPNVLSPIMVSATLGIATAIITESALSFLGFGFPPDFPTWGRLLNDAVDRMTLFPERVLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHH
PGILISLTVLSVNYLGDGLRDALDPRIRGR
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]