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The map label for this gene is acrE [C]

Identifier: 99080471

GI number: 99080471

Start: 667574

End: 668647

Strand: Direct

Name: acrE [C]

Synonym: TM1040_0630

Alternate gene names: 99080471

Gene position: 667574-668647 (Clockwise)

Preceding gene: 99080470

Following gene: 99080472

Centisome position: 20.86

GC content: 61.73

Gene sequence:

>1074_bases
ATGAAAATGACGTCAATCCGGGCGGTGATGCTTGGGGCGATTTTGGCGACCCCGATGGCGGCTGGCGTAGCCGCACAGGC
GCAAGACGCAACGCCGGAACAGGTGCTTTTGAAACCTGTGAAGCTGATGACCGCCAATGGTGGCTCGGCGCCGCTGGAGC
GGAGCTTTTTTGGCCAGGTAGCGGCCAAGGAAACCGTTGATCTGGCCTTTCAGGTGGGTGGGCAAGTGTTGAAGCTTCCG
ATTACCGAAGGCGACGAGATCCCCAAGGGCGGGCTGATCGCGCAGCTGGATCTGGAGACGTTTCAGCTTCAACTCGAGCA
AGCGGTGCTGAATAAACAGCAAGCGGATCGCACCAAGGAACGCAACGCGCGCCTCGCGGGTACCGTGAGCCAGGTGGCGA
TTGAAGATGCCGAAACCGCCGCCGGGCTGGCAGAGGTGGCCTTGCGCACGGCGCAGACGAACCTCGATCATGCAACGCTC
TATGCACCGTTTGATGCCCTGGTGGCGCGGCGCGAGGTGGCGCAGTTTTCTACTGTTTCTGCGGGGACGCCAATTGCGCG
CCTGCATGATATGTCCGAATTGCACGTCGAAATCGACGTGCCAGAGCTTCTGTTCCAGAAGGCGAACGAGAGCGATGCGT
TCGAAATCGTGGCCTCTTTCCCCGGAAGCAGCAAAGAATACCCGCTTCAGATCGTCGAATATGTCGCCGAAGCCTCTGCC
GTGGGGCAGACCTACCGCGTGACCCTTTCGATGGAGCCGCCGGAAGATCGTCACATCCTGCCGGGGGCCTCGACCACCGT
GAGCGTGCGCGTCTCGACCGGCCTGCATCGTATCGCACTTCCGGTGACCGCCATCGTGACCACGCCAGAAGGCAAGACCG
GTGTGATGGTCTTTACCCCCACGGGCGCGGACGCGGGCTCGGTGACATGGACCGAAGTAGAGATCGCGCCCAACCAGTTC
GGCACGTTTGATGTGCTCTCCGGTGTGGAGGACGGCGACGAAGTCGTTCTCACCGGGGGCGCCGCGCTCAAGGACGGGCA
GGCGGTGCGCCGCTTTGTCGGTTTCAGCAATTGA

Upstream 100 bases:

>100_bases
TCACGCGGGAAGAAGCAGAAATCCTCGCCCGGCTCGCACAAAAAATTCACAATAAGGCCGTTCAGTCGGGCGCTGTGGCA
CCCTGTGAAGGAGATCAAAC

Downstream 100 bases:

>100_bases
GGCTCTGAAACATGGACATTGCACGCGGATCAATTCAACGGCCGCTTTATACGTGGCTGATCATGCTGTTTGCCCTCTTT
GGGGGCATCTGGGGCTTTCT

Product: secretion protein HlyD

Products: NA

Alternate protein names: RND Family Efflux Transporter MFP Subunit; Membrane-Fusion Protein; Secretion Protein HlyD; Multidrug Resistance Protein; HlyD Family Secretion Protein; Auxiliary Transport Protein MFP Family; Efflux Protein; Periplasmic Linker Protein; Acriflavin Resistance Periplasmic Protein; RND Efflux Membrane Fusion Protein; Efflux Transporter Rnd Family Mfp Subunit; RND Efflux System Membrane Fusion Protein; Membrane Fusion Protein; Secretion Protein; Lipoprotein; RND Family Efflux System Membrane Fusion Protein; Transport/Efflux Transmembrane Protein; Acriflavin Resistance Protein E; Efflux Transporter; Periplasmic Linker Protein Multidrug Resistance Protein; Efflux Transporter Component; Linker Protein; Multidrug RND Transporter Membrane Fusion Protein; Component Of Multidrug Efflux System; Multidrug Efflux System HlyD Family Transmembrane Protein; Cation/Multidrug Efflux System Mebrane-Fusion Component; Efflux System Protein; Multidrug ABC Transporter; HlyD-Family Secretion Protein; RND Family Resistance-Nodulation- Efflux Pump; Cation Efflux System Protein; HlyD-Like Secretion Protein; AcrA/E Family Efflux Transporter MFP Subunit; RND Family Multidrug Transporter Membrane Fusion Protein; Secretion Protein HlyD Family; HlyD Family Efflux Transporter Component; Secretion Protein Family Hlyd; RND Superfamily Transport Protein Membrane-Fusion Protein; Organic Solvent Efflux Pump; RND/Acr Family Transmembrane Transporter

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKMTSIRAVMLGAILATPMAAGVAAQAQDATPEQVLLKPVKLMTANGGSAPLERSFFGQVAAKETVDLAFQVGGQVLKLP
ITEGDEIPKGGLIAQLDLETFQLQLEQAVLNKQQADRTKERNARLAGTVSQVAIEDAETAAGLAEVALRTAQTNLDHATL
YAPFDALVARREVAQFSTVSAGTPIARLHDMSELHVEIDVPELLFQKANESDAFEIVASFPGSSKEYPLQIVEYVAEASA
VGQTYRVTLSMEPPEDRHILPGASTTVSVRVSTGLHRIALPVTAIVTTPEGKTGVMVFTPTGADAGSVTWTEVEIAPNQF
GTFDVLSGVEDGDEVVLTGGAALKDGQAVRRFVGFSN

Sequences:

>Translated_357_residues
MKMTSIRAVMLGAILATPMAAGVAAQAQDATPEQVLLKPVKLMTANGGSAPLERSFFGQVAAKETVDLAFQVGGQVLKLP
ITEGDEIPKGGLIAQLDLETFQLQLEQAVLNKQQADRTKERNARLAGTVSQVAIEDAETAAGLAEVALRTAQTNLDHATL
YAPFDALVARREVAQFSTVSAGTPIARLHDMSELHVEIDVPELLFQKANESDAFEIVASFPGSSKEYPLQIVEYVAEASA
VGQTYRVTLSMEPPEDRHILPGASTTVSVRVSTGLHRIALPVTAIVTTPEGKTGVMVFTPTGADAGSVTWTEVEIAPNQF
GTFDVLSGVEDGDEVVLTGGAALKDGQAVRRFVGFSN
>Mature_357_residues
MKMTSIRAVMLGAILATPMAAGVAAQAQDATPEQVLLKPVKLMTANGGSAPLERSFFGQVAAKETVDLAFQVGGQVLKLP
ITEGDEIPKGGLIAQLDLETFQLQLEQAVLNKQQADRTKERNARLAGTVSQVAIEDAETAAGLAEVALRTAQTNLDHATL
YAPFDALVARREVAQFSTVSAGTPIARLHDMSELHVEIDVPELLFQKANESDAFEIVASFPGSSKEYPLQIVEYVAEASA
VGQTYRVTLSMEPPEDRHILPGASTTVSVRVSTGLHRIALPVTAIVTTPEGKTGVMVFTPTGADAGSVTWTEVEIAPNQF
GTFDVLSGVEDGDEVVLTGGAALKDGQAVRRFVGFSN

Specific function: May Affect Specific Membrane Functions, Such As Septum Formation During Cell Division, And Cell Membrane Permeability. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37769; Mature: 37769

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMTSIRAVMLGAILATPMAAGVAAQAQDATPEQVLLKPVKLMTANGGSAPLERSFFGQV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHH
AAKETVDLAFQVGGQVLKLPITEGDEIPKGGLIAQLDLETFQLQLEQAVLNKQQADRTKE
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RNARLAGTVSQVAIEDAETAAGLAEVALRTAQTNLDHATLYAPFDALVARREVAQFSTVS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCC
AGTPIARLHDMSELHVEIDVPELLFQKANESDAFEIVASFPGSSKEYPLQIVEYVAEASA
CCCCHHHHCCCCCEEEEECCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
VGQTYRVTLSMEPPEDRHILPGASTTVSVRVSTGLHRIALPVTAIVTTPEGKTGVMVFTP
CCCEEEEEEEECCCCCCEECCCCCCEEEEEECCCCEEEEEEEEEEEECCCCCCEEEEEEC
TGADAGSVTWTEVEIAPNQFGTFDVLSGVEDGDEVVLTGGAALKDGQAVRRFVGFSN
CCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MKMTSIRAVMLGAILATPMAAGVAAQAQDATPEQVLLKPVKLMTANGGSAPLERSFFGQV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHH
AAKETVDLAFQVGGQVLKLPITEGDEIPKGGLIAQLDLETFQLQLEQAVLNKQQADRTKE
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RNARLAGTVSQVAIEDAETAAGLAEVALRTAQTNLDHATLYAPFDALVARREVAQFSTVS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCC
AGTPIARLHDMSELHVEIDVPELLFQKANESDAFEIVASFPGSSKEYPLQIVEYVAEASA
CCCCHHHHCCCCCEEEEECCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
VGQTYRVTLSMEPPEDRHILPGASTTVSVRVSTGLHRIALPVTAIVTTPEGKTGVMVFTP
CCCEEEEEEEECCCCCCEECCCCCCEEEEEECCCCEEEEEEEEEEEECCCCCCEEEEEEC
TGADAGSVTWTEVEIAPNQFGTFDVLSGVEDGDEVVLTGGAALKDGQAVRRFVGFSN
CCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA