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The map label for this gene is paaG [H]

Identifier: 99080279

GI number: 99080279

Start: 455317

End: 456102

Strand: Direct

Name: paaG [H]

Synonym: TM1040_0438

Alternate gene names: 99080279

Gene position: 455317-456102 (Clockwise)

Preceding gene: 99080276

Following gene: 99080280

Centisome position: 14.22

GC content: 62.72

Gene sequence:

>786_bases
ATGGAACAGAGCATTCTGACACAGGATCACGACACATGGTGCGAGATCACGCTGAACCGCCCGGATCGGCTCAATGCGTT
TACCGATGAGATGCATCTGGCCCTGCGTGCCGCTTTGGAAGAGGCGCGCGACTCTGGAAAGCGGGCGTTGCTGCTCACGG
GTGCTGGGCGCGGGTTTTGCGCGGGTCAGGATCTGTCGGCGCGCAATCCGGACGCGGCGGGAGGCCCCGTGGATTTGGGC
TATACGGTGCGCACGTTTTATGCGCCACTCGTGAATCTGATCCGATCGCTGGAGTTTCCGGTCGTCTGCGCCGTCAATGG
CGTTGCCGCAGGGGCAGGGGCGAACCTGTCGCTGGCCGCAGACATTGTGCTCGCTGCACAGAGCGCGAAGTTCATCCAGT
CTTTTGCCAAGGTCGGCCTCATCCCCGACACCGCTGGCAGCTATCACCTGCCGCGCCTACTGGGCGAGGCCCGTGCCAAG
GCTCTGGCCTTGACCGGAGAGCCTCTGAGTGCCGAACAGGCCGCGGATTGGGGACTCATTTGGAAATGCGTTGCGGATGA
GGCGTTGATGGACGAGGCCCGCACCCTGACGGCAAAGCTCGCCGACGGGCCGACACTGGGGCTGGGGCTGACCAAATCTC
TGATCCAGACCTCGGGTGCCTATACGCTTGCAGAGCAACTCGAGCGTGAGGCGGATGCGATGAAGACCTGTGGCGAGAGC
GCGGATTACGCCGAAGGTGTGCGCGCCTTTCTGGAAAAACGAACGCCCGTGTTTCGGGGGCAATAA

Upstream 100 bases:

>100_bases
GCTCATTTTCCTGATTGAATATATTGACCGTCCGGTCGGTTTATGCAAGTCTTTTCCCAATCGAGCGCGAAATCGGTCGC
CAGGGGCAAGGGGAGGGCTC

Downstream 100 bases:

>100_bases
TCCATGTCATTGACCGCACAACAACGGGCAGAGAAATCCGCACAGGCCATGTGGGCCGACGATCAGGCGTCCAAATGGGC
CGGCATGGGCATCGAACGTG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MEQSILTQDHDTWCEITLNRPDRLNAFTDEMHLALRAALEEARDSGKRALLLTGAGRGFCAGQDLSARNPDAAGGPVDLG
YTVRTFYAPLVNLIRSLEFPVVCAVNGVAAGAGANLSLAADIVLAAQSAKFIQSFAKVGLIPDTAGSYHLPRLLGEARAK
ALALTGEPLSAEQAADWGLIWKCVADEALMDEARTLTAKLADGPTLGLGLTKSLIQTSGAYTLAEQLEREADAMKTCGES
ADYAEGVRAFLEKRTPVFRGQ

Sequences:

>Translated_261_residues
MEQSILTQDHDTWCEITLNRPDRLNAFTDEMHLALRAALEEARDSGKRALLLTGAGRGFCAGQDLSARNPDAAGGPVDLG
YTVRTFYAPLVNLIRSLEFPVVCAVNGVAAGAGANLSLAADIVLAAQSAKFIQSFAKVGLIPDTAGSYHLPRLLGEARAK
ALALTGEPLSAEQAADWGLIWKCVADEALMDEARTLTAKLADGPTLGLGLTKSLIQTSGAYTLAEQLEREADAMKTCGES
ADYAEGVRAFLEKRTPVFRGQ
>Mature_261_residues
MEQSILTQDHDTWCEITLNRPDRLNAFTDEMHLALRAALEEARDSGKRALLLTGAGRGFCAGQDLSARNPDAAGGPVDLG
YTVRTFYAPLVNLIRSLEFPVVCAVNGVAAGAGANLSLAADIVLAAQSAKFIQSFAKVGLIPDTAGSYHLPRLLGEARAK
ALALTGEPLSAEQAADWGLIWKCVADEALMDEARTLTAKLADGPTLGLGLTKSLIQTSGAYTLAEQLEREADAMKTCGES
ADYAEGVRAFLEKRTPVFRGQ

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI4757968, Length=262, Percent_Identity=25.9541984732824, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI49355787, Length=262, Percent_Identity=25.9541984732824, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI45643119, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI260275230, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI260274832, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI25453481, Length=262, Percent_Identity=25.5725190839695, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI51538573, Length=262, Percent_Identity=25.5725190839695, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=24.5210727969349, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=24.5210727969349, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=29.8804780876494, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI221307494, Length=261, Percent_Identity=24.5210727969349, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=28.4, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4757966, Length=256, Percent_Identity=25.78125, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI51538581, Length=256, Percent_Identity=25.78125, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI116235487, Length=234, Percent_Identity=26.4957264957265, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI37594471, Length=233, Percent_Identity=30.4721030042918, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI37594469, Length=233, Percent_Identity=30.4721030042918, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI213417737, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI157694516, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=54.9618320610687, Blast_Score=245, Evalue=2e-66,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=32.8413284132841, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=31.5789473684211, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082183, Length=250, Percent_Identity=25.2, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788597, Length=251, Percent_Identity=29.8804780876494, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788682, Length=267, Percent_Identity=25.8426966292135, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=242, Percent_Identity=30.9917355371901, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17535521, Length=244, Percent_Identity=29.5081967213115, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=242, Percent_Identity=30.5785123966942, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17549921, Length=216, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=241, Percent_Identity=29.8755186721992, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=227, Percent_Identity=25.9911894273128, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=211, Percent_Identity=27.0142180094787, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=171, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=204, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129971, Length=244, Percent_Identity=32.7868852459016, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24653477, Length=244, Percent_Identity=32.7868852459016, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922422, Length=258, Percent_Identity=29.0697674418605, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24653139, Length=253, Percent_Identity=32.8063241106719, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654903, Length=242, Percent_Identity=25.2066115702479, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920382, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571729, Length=167, Percent_Identity=31.7365269461078, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571730, Length=167, Percent_Identity=31.7365269461078, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357171, Length=258, Percent_Identity=27.5193798449612, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27708; Mature: 27708

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSILTQDHDTWCEITLNRPDRLNAFTDEMHLALRAALEEARDSGKRALLLTGAGRGFC
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
AGQDLSARNPDAAGGPVDLGYTVRTFYAPLVNLIRSLEFPVVCAVNGVAAGAGANLSLAA
CCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCCCCHHHH
DIVLAAQSAKFIQSFAKVGLIPDTAGSYHLPRLLGEARAKALALTGEPLSAEQAADWGLI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCHHHHCCCHHH
WKCVADEALMDEARTLTAKLADGPTLGLGLTKSLIQTSGAYTLAEQLEREADAMKTCGES
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
ADYAEGVRAFLEKRTPVFRGQ
CHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEQSILTQDHDTWCEITLNRPDRLNAFTDEMHLALRAALEEARDSGKRALLLTGAGRGFC
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
AGQDLSARNPDAAGGPVDLGYTVRTFYAPLVNLIRSLEFPVVCAVNGVAAGAGANLSLAA
CCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCCCCHHHH
DIVLAAQSAKFIQSFAKVGLIPDTAGSYHLPRLLGEARAKALALTGEPLSAEQAADWGLI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCHHHHCCCHHH
WKCVADEALMDEARTLTAKLADGPTLGLGLTKSLIQTSGAYTLAEQLEREADAMKTCGES
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
ADYAEGVRAFLEKRTPVFRGQ
CHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]