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The map label for this gene is betI [H]

Identifier: 99080276

GI number: 99080276

Start: 451273

End: 451926

Strand: Direct

Name: betI [H]

Synonym: TM1040_0435

Alternate gene names: 99080276

Gene position: 451273-451926 (Clockwise)

Preceding gene: 99080266

Following gene: 99080279

Centisome position: 14.1

GC content: 56.42

Gene sequence:

>654_bases
ATGTCAGACAACTTGCCTAAAAAGCAGCCACGAACCGCACCGCCCGAAGCCCGGCGTGAGCAGTTGATCGATGCGACCAT
CACTGCAATCAGCACATATGGTCTCTCGGGAACAACACTGGCGAAGGTCACGGCGGAGGCAGGTCTGTCGCTTGGGCTGG
TTAATTTCCATTTCAAAAGCAAGGAGGCGCTTCTGACGGCAACGTTGACGCATCTTGCAGACGAACACCGCGCCCTTTGG
TTCACAAGGTCCTCACAGCCGGATGTGTCTGCCGCTGACAAACTGAAGCTCATCGTCGACGCGCAGTTTCACGCCAAGAT
CTGCAACCGCCGCAAGCTTTCGGTCTGGTTTGCATTCTTCGGTGAGAGTCGCCCGCGCAAAGCCTATCGGGAGCTGACTG
GCCCCCTCGATGAGGAGCGTCAGATTGCGACCTCTCGCTTGTGTGCGGACATCATAGCAGAGGGTGGCTACAGCGGCATC
GATTCCGATACGGTTTCGGCGATGCTCGAAAGCCTCTTTGACGGGTTCTGGCTCAATATTCTGATGTATCCAGACCGCTT
TACACGGCAGTCAGCCAAGGCGCAGGTTCTGTCGTATCTGCGGCTTTGCTTTCCGCAGCACTTCACGTGCCTCGATGCCG
AAACGTTTGCATGA

Upstream 100 bases:

>100_bases
GTCTCAACTCCTGCAGCGAACTCTAATTTGATCAAATGGCTAGCTTGACCCTAAGCCAAAATCAAGAAATTGATTGAATG
AGCATTCAGTGGAGTGGATA

Downstream 100 bases:

>100_bases
GTGTCGTGCGTGGGACAAGTGCCTGCACAGGCGTGTGCCCATGGTGTTGGCTGTGTGTCTGTTGTGGGAAGGGTGGTAGC
GGAGGAGGGACTTGAACCCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSDNLPKKQPRTAPPEARREQLIDATITAISTYGLSGTTLAKVTAEAGLSLGLVNFHFKSKEALLTATLTHLADEHRALW
FTRSSQPDVSAADKLKLIVDAQFHAKICNRRKLSVWFAFFGESRPRKAYRELTGPLDEERQIATSRLCADIIAEGGYSGI
DSDTVSAMLESLFDGFWLNILMYPDRFTRQSAKAQVLSYLRLCFPQHFTCLDAETFA

Sequences:

>Translated_217_residues
MSDNLPKKQPRTAPPEARREQLIDATITAISTYGLSGTTLAKVTAEAGLSLGLVNFHFKSKEALLTATLTHLADEHRALW
FTRSSQPDVSAADKLKLIVDAQFHAKICNRRKLSVWFAFFGESRPRKAYRELTGPLDEERQIATSRLCADIIAEGGYSGI
DSDTVSAMLESLFDGFWLNILMYPDRFTRQSAKAQVLSYLRLCFPQHFTCLDAETFA
>Mature_216_residues
SDNLPKKQPRTAPPEARREQLIDATITAISTYGLSGTTLAKVTAEAGLSLGLVNFHFKSKEALLTATLTHLADEHRALWF
TRSSQPDVSAADKLKLIVDAQFHAKICNRRKLSVWFAFFGESRPRKAYRELTGPLDEERQIATSRLCADIIAEGGYSGID
SDTVSAMLESLFDGFWLNILMYPDRFTRQSAKAQVLSYLRLCFPQHFTCLDAETFA

Specific function: Repressor involved in choline regulation of the bet genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786505, Length=182, Percent_Identity=27.4725274725275, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR017757
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24266; Mature: 24135

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNLPKKQPRTAPPEARREQLIDATITAISTYGLSGTTLAKVTAEAGLSLGLVNFHFKS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEECC
KEALLTATLTHLADEHRALWFTRSSQPDVSAADKLKLIVDAQFHAKICNRRKLSVWFAFF
CHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHEEEEECCHHHHHHHCCCHHEEEEEEC
GESRPRKAYRELTGPLDEERQIATSRLCADIIAEGGYSGIDSDTVSAMLESLFDGFWLNI
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEHE
LMYPDRFTRQSAKAQVLSYLRLCFPQHFTCLDAETFA
EECCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHCC
>Mature Secondary Structure 
SDNLPKKQPRTAPPEARREQLIDATITAISTYGLSGTTLAKVTAEAGLSLGLVNFHFKS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEECC
KEALLTATLTHLADEHRALWFTRSSQPDVSAADKLKLIVDAQFHAKICNRRKLSVWFAFF
CHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHEEEEECCHHHHHHHCCCHHEEEEEEC
GESRPRKAYRELTGPLDEERQIATSRLCADIIAEGGYSGIDSDTVSAMLESLFDGFWLNI
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEHE
LMYPDRFTRQSAKAQVLSYLRLCFPQHFTCLDAETFA
EECCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA