| Definition | Ruegeria sp. TM1040, complete genome. |
|---|---|
| Accession | NC_008044 |
| Length | 3,200,938 |
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The map label for this gene is polS [H]
Identifier: 99080268
GI number: 99080268
Start: 439386
End: 440156
Strand: Reverse
Name: polS [H]
Synonym: TM1040_0427
Alternate gene names: 99080268
Gene position: 440156-439386 (Counterclockwise)
Preceding gene: 99080269
Following gene: 99080267
Centisome position: 13.75
GC content: 59.14
Gene sequence:
>771_bases ATGAGACTTGAAGGAAAAACCGCCCTGATCACCGGCGCAGCCCGTGGCATCGGGCGCAGCTTTGCCGAGGCCTACATTCG CGAAGGTGCCCGCGTCGCGGTCGCTGATATCGACACTGAACGCGCGCGCCAGACGGCACTCGAGCTCGGCGACCAAGCGG TTGCGATAGAACTGGACGTGACCTGCCAAGAGAGCATCGAGCGCGCGGTCGAGCAAACCGTCGAGGCCTTGGGGTGCATT GATATTCTCGTCAACAACGCCGCGATTTTCACCGCCGCACCCATCACGGAAATCCACCGCGACGATTTTGAACGCGTATT CGACATCAATGTTGCCGGGACGCTGTTCACCATGCAGGCGGTTGCGAAACACATGATTTCGCGTGGTGCCGGTGGCAAGA TCATCAATATGGCCAGTCAAGCCGGACGACGCGGCGAGGCTCTGGTCGCTGTATACTGCGCCTCCAAGGCGGCGATCATC AGTCTGACGCAGTCAGCGGGGCTGAACCTCATTCAGCACGGGATCAATGTGAATGCCATCGCCCCCGGTGTGGTGGATGG CGAGCACTGGGATGGCGTAGATGCCTTTTTTGCAAAATATGAAAACAAAGCCCCCGGCGAAAAAAAACGCGAAGTGGGCG ACGCCGTGCCCTTTGGGCGCATGGGAACCGCAGATGATCTGACCGGTATGGCGATCTTTCTCGCCAGCGCTGAGGCCGAC TATGTGGTGTCGCAGACCTATAACGTCGACGGCGGAAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases CCGACGGCGAGGTTGGCTTTCGCCACGGCGATCGGGTCAGCCTGACGCCACGTACGGATGTGATGCATCGCTTTGACGCC CAAGGCCTGAGGATCCCCTA
Downstream 100 bases:
>100_bases TGACCTCGCTGCGCCTTTCAAACGACACTCTCTCGGATTTGCCCAAACATATCACGCGCCCGACCTATGATCGCGCGGCG CTGACGGCGGGCATCCTTCA
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MRLEGKTALITGAARGIGRSFAEAYIREGARVAVADIDTERARQTALELGDQAVAIELDVTCQESIERAVEQTVEALGCI DILVNNAAIFTAAPITEIHRDDFERVFDINVAGTLFTMQAVAKHMISRGAGGKIINMASQAGRRGEALVAVYCASKAAII SLTQSAGLNLIQHGINVNAIAPGVVDGEHWDGVDAFFAKYENKAPGEKKREVGDAVPFGRMGTADDLTGMAIFLASAEAD YVVSQTYNVDGGNWMS
Sequences:
>Translated_256_residues MRLEGKTALITGAARGIGRSFAEAYIREGARVAVADIDTERARQTALELGDQAVAIELDVTCQESIERAVEQTVEALGCI DILVNNAAIFTAAPITEIHRDDFERVFDINVAGTLFTMQAVAKHMISRGAGGKIINMASQAGRRGEALVAVYCASKAAII SLTQSAGLNLIQHGINVNAIAPGVVDGEHWDGVDAFFAKYENKAPGEKKREVGDAVPFGRMGTADDLTGMAIFLASAEAD YVVSQTYNVDGGNWMS >Mature_256_residues MRLEGKTALITGAARGIGRSFAEAYIREGARVAVADIDTERARQTALELGDQAVAIELDVTCQESIERAVEQTVEALGCI DILVNNAAIFTAAPITEIHRDDFERVFDINVAGTLFTMQAVAKHMISRGAGGKIINMASQAGRRGEALVAVYCASKAAII SLTQSAGLNLIQHGINVNAIAPGVVDGEHWDGVDAFFAKYENKAPGEKKREVGDAVPFGRMGTADDLTGMAIFLASAEAD YVVSQTYNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=38.5786802030457, Blast_Score=119, Evalue=2e-27, Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=30.7392996108949, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=30.5970149253731, Blast_Score=118, Evalue=6e-27, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=30.2325581395349, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=27.1317829457364, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=28.3400809716599, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=37.7142857142857, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=31.304347826087, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=31.3725490196078, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=29.3436293436293, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=32.6424870466321, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=24.8031496062992, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI83715985, Length=184, Percent_Identity=30.9782608695652, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=28.3505154639175, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=26.2886597938144, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI223718074, Length=187, Percent_Identity=31.5508021390374, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI225579078, Length=204, Percent_Identity=29.9019607843137, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=22.9571984435798, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI22507405, Length=190, Percent_Identity=30, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI7706318, Length=213, Percent_Identity=28.6384976525822, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI157739938, Length=198, Percent_Identity=23.2323232323232, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI25282469, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI150247226, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI166795268, Length=205, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=34.765625, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=36.328125, Blast_Score=138, Evalue=4e-34, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=34.9809885931559, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=32.5490196078431, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=30.6772908366534, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=31.1023622047244, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.90625, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=30, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=32.5490196078431, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=30.2325581395349, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=32.295719844358, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=30.1587301587302, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=31.7204301075269, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787526, Length=188, Percent_Identity=30.3191489361702, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1788891, Length=185, Percent_Identity=28.6486486486486, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1786701, Length=205, Percent_Identity=27.8048780487805, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.1115241635688, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=30.4511278195489, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=30.1470588235294, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=29.6875, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=28.8888888888889, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=27.8195488721804, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=28.4132841328413, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=28.3464566929134, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=27.6752767527675, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=28.6245353159851, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=29.9212598425197, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=27.8810408921933, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=29.1970802919708, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=29.4416243654822, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.2388059701493, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=29.5620437956204, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=28.9473684210526, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=29.8507462686567, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=26.1363636363636, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=27.1739130434783, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.8195488721804, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=25.9541984732824, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=28.2828282828283, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=28.2527881040892, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=29.1457286432161, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=31.8181818181818, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=25.8823529411765, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17567345, Length=176, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=28.0769230769231, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=28.3505154639175, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=22.3529411764706, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=25.1968503937008, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI115534660, Length=186, Percent_Identity=28.494623655914, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=26.9430051813472, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=29.6153846153846, Blast_Score=95, Evalue=8e-21, Organism=Saccharomyces cerevisiae, GI6323882, Length=255, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=7e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=28.6458333333333, Blast_Score=82, Evalue=6e-17, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.8063241106719, Blast_Score=124, Evalue=5e-29, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=30.4347826086957, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=29.3436293436293, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI17737361, Length=212, Percent_Identity=33.0188679245283, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=34.2857142857143, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.1338582677165, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=29.3436293436293, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=28.740157480315, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=27.7486910994764, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=26.8, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=31.413612565445, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=29.0566037735849, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665243, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI221331218, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=26.7015706806283, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI221331216, Length=191, Percent_Identity=29.8429319371728, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665247, Length=191, Percent_Identity=29.8429319371728, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24648944, Length=236, Percent_Identity=27.5423728813559, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI161076371, Length=204, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24663911, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355631, Length=166, Percent_Identity=26.5060240963855, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI28571387, Length=257, Percent_Identity=26.0700389105058, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 27193; Mature: 27193
Theoretical pI: Translated: 4.60; Mature: 4.60
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLEGKTALITGAARGIGRSFAEAYIREGARVAVADIDTERARQTALELGDQAVAIELDV CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEC TCQESIERAVEQTVEALGCIDILVNNAAIFTAAPITEIHRDDFERVFDINVAGTLFTMQA CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEEEECCHHHHHHHHH VAKHMISRGAGGKIINMASQAGRRGEALVAVYCASKAAIISLTQSAGLNLIQHGINVNAI HHHHHHHCCCCCCEEEHHHHCCCCCCEEEEEEECCCEEEEEEHHHHCHHHHHHCCCCEEE APGVVDGEHWDGVDAFFAKYENKAPGEKKREVGDAVPFGRMGTADDLTGMAIFLASAEAD CCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCC YVVSQTYNVDGGNWMS EEEEEEEECCCCCCCC >Mature Secondary Structure MRLEGKTALITGAARGIGRSFAEAYIREGARVAVADIDTERARQTALELGDQAVAIELDV CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEC TCQESIERAVEQTVEALGCIDILVNNAAIFTAAPITEIHRDDFERVFDINVAGTLFTMQA CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEEEECCHHHHHHHHH VAKHMISRGAGGKIINMASQAGRRGEALVAVYCASKAAIISLTQSAGLNLIQHGINVNAI HHHHHHHCCCCCCEEEHHHHCCCCCCEEEEEEECCCEEEEEEHHHHCHHHHHHCCCCEEE APGVVDGEHWDGVDAFFAKYENKAPGEKKREVGDAVPFGRMGTADDLTGMAIFLASAEAD CCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCC YVVSQTYNVDGGNWMS EEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]