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The map label for this gene is rpoB

Identifier: 99080075

GI number: 99080075

Start: 247712

End: 251851

Strand: Direct

Name: rpoB

Synonym: TM1040_0234

Alternate gene names: 99080075

Gene position: 247712-251851 (Clockwise)

Preceding gene: 99080074

Following gene: 99080076

Centisome position: 7.74

GC content: 58.99

Gene sequence:

>4140_bases
ATGGCTCAAACGTTCCTTGGCCAGAAACGTCTTCGCAAATATTACGGCAAAATCCGCGAAGTGCTGGATATGCCGAACCT
CATTGAGGTTCAGAAATCTTCTTATGATCTTTTCCTGCGCTCCGGTGATGCGCCTCAGCCGCTTGACGGCGAAGGCATCA
AAGGTGTGTTCCAGTCGGTTTTCCCGATCAAGGATTTCAACGAAACCTCCGTTCTGGAGTTCGTGAACTACGCGCTTGAG
CGTCCCAAGTACGACGTTGACGAATGCATGCAGCGTGACATGACCTACAGCGCACCGCTGAAGGTCACTCTGCGCCTGAT
CGTGTTTGATGTCGATGAGGACACCGGCGCGAAATCCGTTAAAGACATCAAGGAACAGGATGTCTTTATGGGCGACATGC
CCCTGATGACCCCGAACGGGACGTTCATCGTGAACGGCACCGAACGTGTGATCGTGTCCCAGATGCACCGCTCACCGGGT
GTGTTCTTTGACCACGATAAGGGCAAAACCCATTCCTCCGGTAAACTGCTGTTTGCCTGCCGCATCATCCCGTATCGCGG
CTCCTGGCTCGACTTCGAATTCGACGCCAAAGACATCGTCTTTGCTCGCATCGACCGTCGCCGCAAACTGCCGGTGACCA
CGCTGCTTTATGCGCTGGGTCTCGACCAGGAAGGCATCATGGATGCCTACTACAACACCGTGAACTTCAAACTTGAGAAG
TCGCGCGGCTGGGTCACGCCCTTCTTCCCCGAGCGTGTGCGTGGCACCCGCCCGACCTATGACCTCGTGGATGCCGCCAC
TGGCGAAATCATCTGCGAAGCAGGCAAGAAAGTCACCCCGCGCGCGGTCAAGAAGATGATCGACGAAGGCAACATTACCG
AGCTGCTCGTTCCGTTCGAGCATATTGTCGGTAAATATGTCGCCAAGGATATCATCAACGAAGAAAACGGCGCGATCTAT
GTCGAAGCGGGCGACGAGCTGACGCTTGAGTATGACAAAGACGGCGACATCATTGGCGGGTCCGTCAAAGAGCTGCTCGA
TGCCGGTATCACCGACATCCCGGTTCTCGACATCGACAACGTCAATGTCGGCCCCTACATGCGCAACACCATGGCGCAGG
ACAAGAACATGTCCCGCGAAACCGCGCTCATGGACATCTACCGCGTGATGCGTCCGGGCGAGCCGCCCACCGTCGAAGCG
GCCTCCGCGCTGTTTGACACCCTGTTTTTTGATTCCGAGCGCTACGACCTGTCGGCCGTTGGTCGCGTGAAGATGAACAT
GCGTCTGGCTCTGGATGCCGAAGACACTCAGCGGACCCTGCGCAAAGAAGACATCGTCGCCTGTATCAAGGCGCTGGTGG
AGCTGCGTGACGGCAAGGGCGACGTGGACGACATCGACCACCTCGGCAACCGCCGCGTGCGTTCCGTGGGCGAGCTCATG
GAAAACCAGTACCGCGTTGGTCTCCTGCGCATGGAGCGCGCGATCAAAGAGCGTATGTCCTCTGTCGAGATCGACACCGT
GATGCCGCAGGACCTGATCAACGCCAAGCCCGCTGCTGCGGCTGTGCGTGAATTCTTTGGCTCCTCGCAGCTGTCGCAGT
TCATGGACCAAACGAACCCGCTGTCGGAAGTCACCCACAAACGCCGTCTCTCGGCGCTTGGCCCCGGTGGTCTGACCCGC
GAGCGTGCCGGCTTTGAGGTGCGCGACGTTCACCCGACCCACTATGGCCGGATGTGTCCGATTGAAACGCCGGAAGGTCC
GAACATTGGTCTGATCAACTCGCTGGCGACCTTTGCCCGCGTGAACAAGTATGGCTTCATCGAGACCCCCTATCGCGTGG
TGAAGGACGGACAAGTGACCGATGAAGTTCACTACATGTCCGCCACCGAGGAAATGCGTCACACCGTGGCGCAGGCGAAC
GCCAACCTCGATGAAGACAACCGCTTTGTGAATGACCTTGTGTCCACCCGTCAGTCGGGCGACTACACGCTGGCTCCGAA
TGAAAGCGTCGACCTGATCGACGTGTCGCCAAAACAGTTGGTATCGGTTGCGGCCTCGCTCATTCCGTTCCTTGAGAACG
ACGACGCGAACCGCGCCCTGATGGGTTCGAACATGCAACGTCAGGCGGTTCCGCTGCTGCGCGCAGAAGCGCCGCTGGTC
GGTACCGGCATCGAGGAAATCGTGGCGCGCGACTCTGGCGCGGCGATCATGGCGAAGCGCGCAGGCGTGATCGACCAGAT
CGACGCTCAGCGTATCGTGATCCGTGCAACCTCCGATCTGGAGCTGGGCGACGCAGGCGTGGACATCTACCGCATGCGCA
AGTTCCAGCGCTCGAACCAGAACACCTGCATCAACCAGCGCCCGCTGGTGAAAGTGGGTCAGACGGTCGAGAAGGGCGAA
GTGATCGCAGATGGTCCCTCCACCGATATGGGTGAACTGGCGCTCGGTAAAAACGTGGTTGTCGCGTTTATGCCGTGGAA
CGGTTACAACTATGAGGACTCCATCCTGATCTCCGAGCGTATCGCGCGTGACGACGTCTTCACCTCGATCCACATCGAGG
AATTCGAAGTCGCCGCTCGTGACACCAAGCTTGGGCCGGAAGAGATCACCCGCGATATTCCGAACGTTGGTGAAGAAGCG
CTGCGCAACCTCGACGAGGCAGGCATCGTCTACATCGGTGCCGATGTGGAGCCGGGCGATATCCTCGTGGGTAAGATCAC
ACCGAAGGGCGAAAGCCCGATGACGCCGGAAGAAAAGCTTCTGCGCGCCATCTTTGGTGAGAAAGCCTCCGACGTGCGTG
ACACCTCGCTGCGTGTGAAGCCGGGCGACTACGGTACTGTTGTTGAGGTTCGCGTCTTCAACCGTCACGGCGTCGAAAAA
GACGAACGTGCCCTGCAGATCGAGCGCGAAGAAGTCGAACGTCTGGCCCGTGACCGGGACGACGAGCTCGGCATTCTGGA
CCGCAACATCTACGCCCGTCTGCGTGACCTTCTGCTCGGCAAAACTGCCGTCAAAGGCCCCAAAGGCGTGCGCGGCAACA
CCGTCATCGACGAGGATCTGCTGGACAACCAGCTAACCCGTGGTCAGTGGTGGATGCTTGCTCTGGAAGAAGAGCAGGAC
GCTCAGATCCTTGAGGCTCTGAACGAGCAGTACGAAGCACAAAAGCGTGCTCTGGACGCCCGTTTCGAGGACAAGGTCGA
GAAGGTCCGCCGCGGCGACGATCTGCCTCCGGGTGTGATGAAGATGGTCAAAGTCTTCATCGCCGTGAAGCGTAAGCTGC
AGCCGGGCGACAAGATGGCCGGTCGTCACGGGAACAAAGGTGTTATCTCTCGCGTGGTGCCGATGGAGGACATGCCGTTC
CTCGCCGATGGTACCCCGGTGGACTTCTGCCTTAACCCGCTCGGCGTGCCGTCGCGTATGAACGTTGGTCAGATCCTTGA
AACCCACATGGGTTGGGCCGCACGCGGCCTGGGTCTGAAAATCGACGACGCACTTCAGGACTATCGCCGCACTGGCGATC
TGACCCCTGTGCGTGATGCGATGCGCGAGGCCTATGGTGAGGACGTTTATGAAGAGGGGATCTCTTCCATGGACGAAACC
CAACTCATCGAGGCTGCTGGTAACGTGACCCGTGGTGTGCCGATCGCAACGCCGGTCTTTGACGGTGCGAAAGAAGATGA
CGTCAACGACGCGCTGGTGCGCGCGGGCTTTGACCAGTCCGGTCAGTCGATCCTGTTCGATGGCCGCACCGGTGAGCAGT
TCGCACGTCCAGTGACCGTGGGCATCAAGTATCTCTTGAAGCTGCACCACCTCGTGGACGACAAGATCCACGCCCGTTCC
ACTGGTCCGTACTCGCTGGTTACCCAGCAGCCGCTCGGTGGTAAGGCACAGTTCGGTGGTCAGCGCTTTGGTGAGATGGA
GGTCTGGGCTCTGGAAGCTTACGGCGCCGCCTACACCCTGCAAGAGATGCTCACCGTGAAATCGGATGACGTCGCTGGCC
GGACCAAGGTCTATGAGTCGATCGTCAAGGGCGAGGACAACTTTGAGGCGGGCGTACCGGAATCGTTCAACGTTCTGGTC
AAAGAAGTCCGCGGCCTCGGCCTGAACATGGAACTCCTGGATGCGGAGGTTGAGGAGTGA

Upstream 100 bases:

>100_bases
TGGCCATGAATTGATCCAGACCACGCTGTCTCTGACGGATGAGGTGCCGGGGCCCGGCGGCTGCCTTGTTTGTTGAGAAC
TCTGAAAGGTGAACTCTGAC

Downstream 100 bases:

>100_bases
GGGGGCTTCCCCTCACCCCACGTCCCCCCTTCCGCAAGATTTGAGGTATCAAAATGAACCAGGAAATCACCAACAACCCG
TTCAACCCGCTGACTCCGCC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1379; Mature: 1378

Protein sequence:

>1379_residues
MAQTFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLRSGDAPQPLDGEGIKGVFQSVFPIKDFNETSVLEFVNYALE
RPKYDVDECMQRDMTYSAPLKVTLRLIVFDVDEDTGAKSVKDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPG
VFFDHDKGKTHSSGKLLFACRIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYALGLDQEGIMDAYYNTVNFKLEK
SRGWVTPFFPERVRGTRPTYDLVDAATGEIICEAGKKVTPRAVKKMIDEGNITELLVPFEHIVGKYVAKDIINEENGAIY
VEAGDELTLEYDKDGDIIGGSVKELLDAGITDIPVLDIDNVNVGPYMRNTMAQDKNMSRETALMDIYRVMRPGEPPTVEA
ASALFDTLFFDSERYDLSAVGRVKMNMRLALDAEDTQRTLRKEDIVACIKALVELRDGKGDVDDIDHLGNRRVRSVGELM
ENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTR
ERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFARVNKYGFIETPYRVVKDGQVTDEVHYMSATEEMRHTVAQAN
ANLDEDNRFVNDLVSTRQSGDYTLAPNESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPLV
GTGIEEIVARDSGAAIMAKRAGVIDQIDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQNTCINQRPLVKVGQTVEKGE
VIADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISERIARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEA
LRNLDEAGIVYIGADVEPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDYGTVVEVRVFNRHGVEK
DERALQIEREEVERLARDRDDELGILDRNIYARLRDLLLGKTAVKGPKGVRGNTVIDEDLLDNQLTRGQWWMLALEEEQD
AQILEALNEQYEAQKRALDARFEDKVEKVRRGDDLPPGVMKMVKVFIAVKRKLQPGDKMAGRHGNKGVISRVVPMEDMPF
LADGTPVDFCLNPLGVPSRMNVGQILETHMGWAARGLGLKIDDALQDYRRTGDLTPVRDAMREAYGEDVYEEGISSMDET
QLIEAAGNVTRGVPIATPVFDGAKEDDVNDALVRAGFDQSGQSILFDGRTGEQFARPVTVGIKYLLKLHHLVDDKIHARS
TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLV
KEVRGLGLNMELLDAEVEE

Sequences:

>Translated_1379_residues
MAQTFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLRSGDAPQPLDGEGIKGVFQSVFPIKDFNETSVLEFVNYALE
RPKYDVDECMQRDMTYSAPLKVTLRLIVFDVDEDTGAKSVKDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPG
VFFDHDKGKTHSSGKLLFACRIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYALGLDQEGIMDAYYNTVNFKLEK
SRGWVTPFFPERVRGTRPTYDLVDAATGEIICEAGKKVTPRAVKKMIDEGNITELLVPFEHIVGKYVAKDIINEENGAIY
VEAGDELTLEYDKDGDIIGGSVKELLDAGITDIPVLDIDNVNVGPYMRNTMAQDKNMSRETALMDIYRVMRPGEPPTVEA
ASALFDTLFFDSERYDLSAVGRVKMNMRLALDAEDTQRTLRKEDIVACIKALVELRDGKGDVDDIDHLGNRRVRSVGELM
ENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTR
ERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFARVNKYGFIETPYRVVKDGQVTDEVHYMSATEEMRHTVAQAN
ANLDEDNRFVNDLVSTRQSGDYTLAPNESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPLV
GTGIEEIVARDSGAAIMAKRAGVIDQIDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQNTCINQRPLVKVGQTVEKGE
VIADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISERIARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEA
LRNLDEAGIVYIGADVEPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDYGTVVEVRVFNRHGVEK
DERALQIEREEVERLARDRDDELGILDRNIYARLRDLLLGKTAVKGPKGVRGNTVIDEDLLDNQLTRGQWWMLALEEEQD
AQILEALNEQYEAQKRALDARFEDKVEKVRRGDDLPPGVMKMVKVFIAVKRKLQPGDKMAGRHGNKGVISRVVPMEDMPF
LADGTPVDFCLNPLGVPSRMNVGQILETHMGWAARGLGLKIDDALQDYRRTGDLTPVRDAMREAYGEDVYEEGISSMDET
QLIEAAGNVTRGVPIATPVFDGAKEDDVNDALVRAGFDQSGQSILFDGRTGEQFARPVTVGIKYLLKLHHLVDDKIHARS
TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLV
KEVRGLGLNMELLDAEVEE
>Mature_1378_residues
AQTFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLRSGDAPQPLDGEGIKGVFQSVFPIKDFNETSVLEFVNYALER
PKYDVDECMQRDMTYSAPLKVTLRLIVFDVDEDTGAKSVKDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPGV
FFDHDKGKTHSSGKLLFACRIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYALGLDQEGIMDAYYNTVNFKLEKS
RGWVTPFFPERVRGTRPTYDLVDAATGEIICEAGKKVTPRAVKKMIDEGNITELLVPFEHIVGKYVAKDIINEENGAIYV
EAGDELTLEYDKDGDIIGGSVKELLDAGITDIPVLDIDNVNVGPYMRNTMAQDKNMSRETALMDIYRVMRPGEPPTVEAA
SALFDTLFFDSERYDLSAVGRVKMNMRLALDAEDTQRTLRKEDIVACIKALVELRDGKGDVDDIDHLGNRRVRSVGELME
NQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRE
RAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFARVNKYGFIETPYRVVKDGQVTDEVHYMSATEEMRHTVAQANA
NLDEDNRFVNDLVSTRQSGDYTLAPNESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPLVG
TGIEEIVARDSGAAIMAKRAGVIDQIDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQNTCINQRPLVKVGQTVEKGEV
IADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISERIARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEAL
RNLDEAGIVYIGADVEPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDYGTVVEVRVFNRHGVEKD
ERALQIEREEVERLARDRDDELGILDRNIYARLRDLLLGKTAVKGPKGVRGNTVIDEDLLDNQLTRGQWWMLALEEEQDA
QILEALNEQYEAQKRALDARFEDKVEKVRRGDDLPPGVMKMVKVFIAVKRKLQPGDKMAGRHGNKGVISRVVPMEDMPFL
ADGTPVDFCLNPLGVPSRMNVGQILETHMGWAARGLGLKIDDALQDYRRTGDLTPVRDAMREAYGEDVYEEGISSMDETQ
LIEAAGNVTRGVPIATPVFDGAKEDDVNDALVRAGFDQSGQSILFDGRTGEQFARPVTVGIKYLLKLHHLVDDKIHARST
GPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLVK
EVRGLGLNMELLDAEVEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=32.295719844358, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=32.295719844358, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI4505941, Length=249, Percent_Identity=30.5220883534137, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI238908503, Length=269, Percent_Identity=31.2267657992565, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI238908505, Length=269, Percent_Identity=31.2267657992565, Blast_Score=110, Evalue=1e-23,
Organism=Escherichia coli, GI1790419, Length=1378, Percent_Identity=57.8374455732946, Blast_Score=1608, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=249, Percent_Identity=31.3253012048193, Blast_Score=123, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17506623, Length=238, Percent_Identity=31.9327731092437, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144348, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324725, Length=310, Percent_Identity=29.6774193548387, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6325267, Length=250, Percent_Identity=31.2, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324781, Length=297, Percent_Identity=26.9360269360269, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17136446, Length=274, Percent_Identity=31.021897810219, Blast_Score=109, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17647877, Length=248, Percent_Identity=28.2258064516129, Blast_Score=97, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136444, Length=114, Percent_Identity=38.5964912280702, Blast_Score=87, Evalue=1e-16,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_SILST (Q1GK49)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612229.1
- ProteinModelPortal:   Q1GK49
- STRING:   Q1GK49
- GeneID:   4076267
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0234
- NMPDR:   fig|292414.1.peg.2572
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   Q1GK49
- ProtClustDB:   PRK00405
- BioCyc:   SSP292414:TM1040_0234-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 153835; Mature: 153704

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLRSGDAPQPLDGEGIKGVFQSV
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCEEEEECCCCCCCCCCCCHHHHHHHH
FPIKDFNETSVLEFVNYALERPKYDVDECMQRDMTYSAPLKVTLRLIVFDVDEDTGAKSV
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCHHH
KDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAC
HHHHHHCCEECCCCEECCCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYALGLDQEGIMDAYYNTVNFKLEK
EEEECCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCEEEEEEEC
SRGWVTPFFPERVRGTRPTYDLVDAATGEIICEAGKKVTPRAVKKMIDEGNITELLVPFE
CCCCCCCCCHHHHCCCCCCHHHHHCCCCHHHCCCCCCCCHHHHHHHHCCCCHHEEHHHHH
HIVGKYVAKDIINEENGAIYVEAGDELTLEYDKDGDIIGGSVKELLDAGITDIPVLDIDN
HHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCEECCHHHHHHHCCCCCCCEEECCC
VNVGPYMRNTMAQDKNMSRETALMDIYRVMRPGEPPTVEAASALFDTLFFDSERYDLSAV
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEC
GRVKMNMRLALDAEDTQRTLRKEDIVACIKALVELRDGKGDVDDIDHLGNRRVRSVGELM
CEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
ENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNP
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCC
LSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFAR
HHHHHHHHHHHHCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VNKYGFIETPYRVVKDGQVTDEVHYMSATEEMRHTVAQANANLDEDNRFVNDLVSTRQSG
HHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DYTLAPNESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPLV
CEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCC
GTGIEEIVARDSGAAIMAKRAGVIDQIDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQ
CCCHHHHHHCCCCCEEEHHHCCCHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
NTCINQRPLVKVGQTVEKGEVIADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISER
CCCCCCCCHHHHCCCHHCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEHHHH
IARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEALRNLDEAGIVYIGADVEPGD
HHHHHHHEEEEHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCC
ILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDYGTVVEVRVFNRHGVEK
EEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCH
DERALQIEREEVERLARDRDDELGILDRNIYARLRDLLLGKTAVKGPKGVRGNTVIDEDL
HHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHH
LDNQLTRGQWWMLALEEEQDAQILEALNEQYEAQKRALDARFEDKVEKVRRGDDLPPGVM
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KMVKVFIAVKRKLQPGDKMAGRHGNKGVISRVVPMEDMPFLADGTPVDFCLNPLGVPSRM
HHHHHHHHHHHHCCCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCCHHHHCCCCCCCCCC
NVGQILETHMGWAARGLGLKIDDALQDYRRTGDLTPVRDAMREAYGEDVYEEGISSMDET
CHHHHHHHHHCHHHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHCCCHHH
QLIEAAGNVTRGVPIATPVFDGAKEDDVNDALVRAGFDQSGQSILFDGRTGEQFARPVTV
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHH
GIKYLLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
HHHHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHH
QEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLVKEVRGLGLNMELLDAEVEE
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCC
>Mature Secondary Structure 
AQTFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLRSGDAPQPLDGEGIKGVFQSV
CCCHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCEEEEECCCCCCCCCCCCHHHHHHHH
FPIKDFNETSVLEFVNYALERPKYDVDECMQRDMTYSAPLKVTLRLIVFDVDEDTGAKSV
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCHHH
KDIKEQDVFMGDMPLMTPNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAC
HHHHHHCCEECCCCEECCCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYALGLDQEGIMDAYYNTVNFKLEK
EEEECCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCEEEEEEEC
SRGWVTPFFPERVRGTRPTYDLVDAATGEIICEAGKKVTPRAVKKMIDEGNITELLVPFE
CCCCCCCCCHHHHCCCCCCHHHHHCCCCHHHCCCCCCCCHHHHHHHHCCCCHHEEHHHHH
HIVGKYVAKDIINEENGAIYVEAGDELTLEYDKDGDIIGGSVKELLDAGITDIPVLDIDN
HHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCEECCHHHHHHHCCCCCCCEEECCC
VNVGPYMRNTMAQDKNMSRETALMDIYRVMRPGEPPTVEAASALFDTLFFDSERYDLSAV
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEC
GRVKMNMRLALDAEDTQRTLRKEDIVACIKALVELRDGKGDVDDIDHLGNRRVRSVGELM
CEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
ENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNP
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCC
LSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFAR
HHHHHHHHHHHHCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VNKYGFIETPYRVVKDGQVTDEVHYMSATEEMRHTVAQANANLDEDNRFVNDLVSTRQSG
HHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DYTLAPNESVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPLV
CEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCC
GTGIEEIVARDSGAAIMAKRAGVIDQIDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQ
CCCHHHHHHCCCCCEEEHHHCCCHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
NTCINQRPLVKVGQTVEKGEVIADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISER
CCCCCCCCHHHHCCCHHCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEHHHH
IARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEALRNLDEAGIVYIGADVEPGD
HHHHHHHEEEEHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCC
ILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDYGTVVEVRVFNRHGVEK
EEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCH
DERALQIEREEVERLARDRDDELGILDRNIYARLRDLLLGKTAVKGPKGVRGNTVIDEDL
HHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHH
LDNQLTRGQWWMLALEEEQDAQILEALNEQYEAQKRALDARFEDKVEKVRRGDDLPPGVM
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KMVKVFIAVKRKLQPGDKMAGRHGNKGVISRVVPMEDMPFLADGTPVDFCLNPLGVPSRM
HHHHHHHHHHHHCCCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCCHHHHCCCCCCCCCC
NVGQILETHMGWAARGLGLKIDDALQDYRRTGDLTPVRDAMREAYGEDVYEEGISSMDET
CHHHHHHHHHCHHHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHCCCHHH
QLIEAAGNVTRGVPIATPVFDGAKEDDVNDALVRAGFDQSGQSILFDGRTGEQFARPVTV
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHH
GIKYLLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
HHHHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHH
QEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLVKEVRGLGLNMELLDAEVEE
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA