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The map label for this gene is ubiH [C]

Identifier: 99079898

GI number: 99079898

Start: 59044

End: 60270

Strand: Reverse

Name: ubiH [C]

Synonym: TM1040_0057

Alternate gene names: 99079898

Gene position: 60270-59044 (Counterclockwise)

Preceding gene: 99079903

Following gene: 99079893

Centisome position: 1.88

GC content: 61.86

Gene sequence:

>1227_bases
ATGACTGATACGCGTGATATCCTGATTGTGGGCGGAGGCCTGAATGGTCCGTCGCTTGCTCTTGCGCTGGCACAGGCTGG
CCATTCTGTGACCCTGATCGACGCGCTTCCGGCGCCCCTGCGCGAGGACGCCGAATTTGACGGCCGTTCCTATGCTCTGG
CGCTTGCCTCGACGCGGCTCCTGCAACAGATCGGGATCTGGGCAGTTATCGAGGATCACGCTCAACCGATGAACGAGATC
AAGGTTAGCGACGGCGTTGCCGGTCGCGGCCCTTCGCCGCTTTTCCTGCATTTTGAGGAAAGCGACCTCGACGAGGGCCC
CATGGGCTACATGGTCGAAGATCGCTACCTGCGCCGCGCCCTTCTGAAAGCACTCGAGGCCGAGCCAAAAATCACCCAGA
TCTCGGGCCAGCCTGTGATCGCACAGACCGTGAGTGCGGATGCCATCACCGTCACTCTCGAAGATGGCACACAGCTCTCG
GGTGCGCTTTTGGTCGGCGCGGATGGACGTCAAAGCGGCACCGCCGCGCGCGCCGGCATCAAGCGCACCGGGTGGGATTA
CGGCCAGACCGCACTGGTCTGCGCTATCTCACATGCGCAACCTCACAACGGCATTGCCCATCAGTTCTTTATGCCGCCGG
GGCCGCTTGCAATTCTGCCGTTGCCGGGCAATCGCAGCTCTATTGTCTGGAGTGAGACTCATGCCGAGGCTGCGCGCATT
CAGGCACTTTCGGATCAGGACTACCTCTCGGTGCTGCGCCCCCGGTTTGGGTCTTTCCTCGGAGAGATCGATTTGGAAGG
CAAGCGCTTCAGCTATCCGCTGAAATTGAGCCTTGCCAATGCCTTTTATGGCGAGCGACTGGCCTTGGTGGGCGATGCGG
CGCATGGGCTGCACCCGATCGCGGGCCAGGGACTCAATGCGGGGCTGCGCGACATCGCCAGCCTTGCAGAAGTTCTGACC
GATGCAGCGCGGCGCGGTGAGGATCTCGCCAGCCCCTTGGTTCTGGCGCGCTATCAACAGTGGCGCCGGTTCGACACCAC
CTCTCTCGCGCTAGCGACAGATGTGTTCAACAAGCTGTTTTCAAACGACAATCCTATCCTGCGCGCCACCCGAGATCTGG
GGCTTGGCCTCACAAATGCACTGCCTGGCCTACGCCGAGGTTTTGTGCGCGAAGCGGCAGGACTTTCGGGAGATTTGCCG
CGCCTGTTGCGCGGGCGCCCGCTCTGA

Upstream 100 bases:

>100_bases
TGACGGGCACCACGCGATCGGCGGGCTGCGGCAGCATGCCTCTGTGCGATGGCATGACAACAGCATGGACAATCCCCCAA
GGCAGCGCATATTGCGAGGC

Downstream 100 bases:

>100_bases
GCGCCCACGTACCGACAGGTTATTCAAGCGGGCGCGCCTCATCCGTCAGCATCACGGGGATACCGTTGCGGATCGGGAAA
GCAAGATTGGCCGCGCGCGA

Product: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase / 2-octaprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTDTRDILIVGGGLNGPSLALALAQAGHSVTLIDALPAPLREDAEFDGRSYALALASTRLLQQIGIWAVIEDHAQPMNEI
KVSDGVAGRGPSPLFLHFEESDLDEGPMGYMVEDRYLRRALLKALEAEPKITQISGQPVIAQTVSADAITVTLEDGTQLS
GALLVGADGRQSGTAARAGIKRTGWDYGQTALVCAISHAQPHNGIAHQFFMPPGPLAILPLPGNRSSIVWSETHAEAARI
QALSDQDYLSVLRPRFGSFLGEIDLEGKRFSYPLKLSLANAFYGERLALVGDAAHGLHPIAGQGLNAGLRDIASLAEVLT
DAARRGEDLASPLVLARYQQWRRFDTTSLALATDVFNKLFSNDNPILRATRDLGLGLTNALPGLRRGFVREAAGLSGDLP
RLLRGRPL

Sequences:

>Translated_408_residues
MTDTRDILIVGGGLNGPSLALALAQAGHSVTLIDALPAPLREDAEFDGRSYALALASTRLLQQIGIWAVIEDHAQPMNEI
KVSDGVAGRGPSPLFLHFEESDLDEGPMGYMVEDRYLRRALLKALEAEPKITQISGQPVIAQTVSADAITVTLEDGTQLS
GALLVGADGRQSGTAARAGIKRTGWDYGQTALVCAISHAQPHNGIAHQFFMPPGPLAILPLPGNRSSIVWSETHAEAARI
QALSDQDYLSVLRPRFGSFLGEIDLEGKRFSYPLKLSLANAFYGERLALVGDAAHGLHPIAGQGLNAGLRDIASLAEVLT
DAARRGEDLASPLVLARYQQWRRFDTTSLALATDVFNKLFSNDNPILRATRDLGLGLTNALPGLRRGFVREAAGLSGDLP
RLLRGRPL
>Mature_407_residues
TDTRDILIVGGGLNGPSLALALAQAGHSVTLIDALPAPLREDAEFDGRSYALALASTRLLQQIGIWAVIEDHAQPMNEIK
VSDGVAGRGPSPLFLHFEESDLDEGPMGYMVEDRYLRRALLKALEAEPKITQISGQPVIAQTVSADAITVTLEDGTQLSG
ALLVGADGRQSGTAARAGIKRTGWDYGQTALVCAISHAQPHNGIAHQFFMPPGPLAILPLPGNRSSIVWSETHAEAARIQ
ALSDQDYLSVLRPRFGSFLGEIDLEGKRFSYPLKLSLANAFYGERLALVGDAAHGLHPIAGQGLNAGLRDIASLAEVLTD
AARRGEDLASPLVLARYQQWRRFDTTSLALATDVFNKLFSNDNPILRATRDLGLGLTNALPGLRRGFVREAAGLSGDLPR
LLRGRPL

Specific function: Oxygenase That Introduces The Hydroxyl Group At Carbon Four Of 2-Octaprenyl-6-Methoxyphenol Resulting In The Formation Of 2-Octaprenyl-6-Methoxy-1,4-Benzoquinone. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=401, Percent_Identity=30.9226932668329, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI32967307, Length=345, Percent_Identity=32.463768115942, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1789274, Length=374, Percent_Identity=36.8983957219251, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1789273, Length=402, Percent_Identity=34.3283582089552, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI1786883, Length=392, Percent_Identity=35.969387755102, Blast_Score=200, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25146631, Length=425, Percent_Identity=28, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321694, Length=460, Percent_Identity=26.304347826087, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19920760, Length=437, Percent_Identity=26.5446224256293, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43683; Mature: 43552

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTRDILIVGGGLNGPSLALALAQAGHSVTLIDALPAPLREDAEFDGRSYALALASTRL
CCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHH
LQQIGIWAVIEDHAQPMNEIKVSDGVAGRGPSPLFLHFEESDLDEGPMGYMVEDRYLRRA
HHHHCCEEEEHHHCCCHHHEEECCCCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHH
LLKALEAEPKITQISGQPVIAQTVSADAITVTLEDGTQLSGALLVGADGRQSGTAARAGI
HHHHHCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCEEEECCCCCCCCCHHHCCC
KRTGWDYGQTALVCAISHAQPHNGIAHQFFMPPGPLAILPLPGNRSSIVWSETHAEAARI
CCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCEEEEEHHHHHHHHH
QALSDQDYLSVLRPRFGSFLGEIDLEGKRFSYPLKLSLANAFYGERLALVGDAAHGLHPI
HHCCCHHHHHHHHHHHHHHHCCEECCCCEECCEEEEEEHHHHCCCEEEEEECCCCCCCCC
AGQGLNAGLRDIASLAEVLTDAARRGEDLASPLVLARYQQWRRFDTTSLALATDVFNKLF
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SNDNPILRATRDLGLGLTNALPGLRRGFVREAAGLSGDLPRLLRGRPL
CCCCCEEEEHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
TDTRDILIVGGGLNGPSLALALAQAGHSVTLIDALPAPLREDAEFDGRSYALALASTRL
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHH
LQQIGIWAVIEDHAQPMNEIKVSDGVAGRGPSPLFLHFEESDLDEGPMGYMVEDRYLRRA
HHHHCCEEEEHHHCCCHHHEEECCCCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHH
LLKALEAEPKITQISGQPVIAQTVSADAITVTLEDGTQLSGALLVGADGRQSGTAARAGI
HHHHHCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCEEEECCCCCCCCCHHHCCC
KRTGWDYGQTALVCAISHAQPHNGIAHQFFMPPGPLAILPLPGNRSSIVWSETHAEAARI
CCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCEEEEEHHHHHHHHH
QALSDQDYLSVLRPRFGSFLGEIDLEGKRFSYPLKLSLANAFYGERLALVGDAAHGLHPI
HHCCCHHHHHHHHHHHHHHHCCEECCCCEECCEEEEEEHHHHCCCEEEEEECCCCCCCCC
AGQGLNAGLRDIASLAEVLTDAARRGEDLASPLVLARYQQWRRFDTTSLALATDVFNKLF
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SNDNPILRATRDLGLGLTNALPGLRRGFVREAAGLSGDLPRLLRGRPL
CCCCCEEEEHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]