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The map label for this gene is trkA [H]

Identifier: 104779335

GI number: 104779335

Start: 22501

End: 23874

Strand: Reverse

Name: trkA [H]

Synonym: PSEEN0022

Alternate gene names: 104779335

Gene position: 23874-22501 (Counterclockwise)

Preceding gene: 104779336

Following gene: 104779334

Centisome position: 0.41

GC content: 65.43

Gene sequence:

>1374_bases
ATGAAGATCATCATCCTCGGCGCAGGGCAGGTGGGCGGCACGCTGGCGGAACACCTGGCCAGCGAAGCCAACGACATCAC
CGTGGTCGACACCGACAGCGAGCGCCTGCGCGACCTGGGCGACCGCCTGGACATCCGCACCGTGCAGGGCCGCGCGTCGC
TGCCGACGGTACTGCGCCAGGCCGGCGCCGACGACGCCGACATGCTGGTGGCGGTAACCAACAGTGACGAGACCAACATG
GTCGCCTGCCAGGTCGCCTACTCGCTGTTCCACACCCCGACCAAGATCGCCCGGGTACGCGAGTCGGCCTACCTCACCCG
TGAAGAGCTGTTCGACAACGACCACATCCCGGTGGACGTGCTGATCAGCCCCGAGCAGGTGGTGACCAACTACATCAAGC
GCCTGATCGAACACCCAGGTTCGCTGCAGGTGATCGACTTCGCCGAGGGCAAGGCCCAGCTGGTGGCGGTCCGGGCCTAC
TACGGCGGCCCGCTGGTGGGCCAGCAACTGCGCCAGATCCGCGCCCACATGCCCAATGTCGACACCCGCGTGGCGGCGAT
CTTCCGCCGCGACCGGCCGATCACCCCGCAGGGCGACACGGTGATCGAGGCCGACGACGAAGTGTTCTTCATCGCCGCGA
AGAAGGACATCCGCGCAGTGATGGGTGAGCTGCGTCGCATCGACGAGACCAACAAGCGCGTGGTCATCGCCGGTGGCGGG
CAGATCGGCGAGCGCCTGGCCGAGGCCATCGAGAGCCGCTACCAGGTGAAGATCATCGAGATGAACCCGGCACGCTGCCG
CCACCTCTCGGAAAACCTCGAGAGCACCGTGGTGCTCCAAGGCAGTGCGTCCGACCGGGACCTGATGCTCGAAGAAAACA
TCGCCGACGCCGACATCTTCCTGGCCCTGACCAACGACGACGAGGCCAACATCATGTCGTCGCTGCTGGCCAAGCGCTTG
GGTGCGCGCAAGGTGATGACCATCATCAACAACCCGGCCTACGTCGACCTGGTGCAGGGCGGCGAGATCGACATCGCCAT
CAGCCCGCAGCTGGCCACCATCGGCACCTTGCTGGCCCACGTGCGCCGCGGCGATATCGTCAGCGTGCACTCGCTGCGCC
GGGGCGCGGCCGAGGCCATCGAGGCGGTGGCCCATGGCGATTCGAAGTCGAGCAAGGTGGTGGGCAAGGCCATCGAGGAC
ATCTCGTTGCCGCCAGGCACCACCATCGGCGCGATCATCCGCGACGAGGAAGTGCTGATCGCCCACGATGACACGGTGAT
CGCGTCGGGCGACCATGTGATCCTGTTCGTTGTGGATAAAAAGCAGATTCGAGACGTGGAGAAACTGTTCCACGTGGGCC
TGAGTTTCTTCTAG

Upstream 100 bases:

>100_bases
CTGCTGGCCCAGGAAGGCGGCCATGACGGGTTCTATTACGCCAAACTGATCAAGATCGCCGCTTCGCGCGGGTAAGAACA
AAAAGGGTAGGGAGTAGCGG

Downstream 100 bases:

>100_bases
GGAGAGACGTGATGCGTGAATCGCTGGAGAAAATGCTGGCCAAGGGTGTGGATAACCCGCTGCTGCGGTTCGGGCTGGGC
AAGGCCTGGCTGGACGAGGG

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKIIILGAGQVGGTLAEHLASEANDITVVDTDSERLRDLGDRLDIRTVQGRASLPTVLRQAGADDADMLVAVTNSDETNM
VACQVAYSLFHTPTKIARVRESAYLTREELFDNDHIPVDVLISPEQVVTNYIKRLIEHPGSLQVIDFAEGKAQLVAVRAY
YGGPLVGQQLRQIRAHMPNVDTRVAAIFRRDRPITPQGDTVIEADDEVFFIAAKKDIRAVMGELRRIDETNKRVVIAGGG
QIGERLAEAIESRYQVKIIEMNPARCRHLSENLESTVVLQGSASDRDLMLEENIADADIFLALTNDDEANIMSSLLAKRL
GARKVMTIINNPAYVDLVQGGEIDIAISPQLATIGTLLAHVRRGDIVSVHSLRRGAAEAIEAVAHGDSKSSKVVGKAIED
ISLPPGTTIGAIIRDEEVLIAHDDTVIASGDHVILFVVDKKQIRDVEKLFHVGLSFF

Sequences:

>Translated_457_residues
MKIIILGAGQVGGTLAEHLASEANDITVVDTDSERLRDLGDRLDIRTVQGRASLPTVLRQAGADDADMLVAVTNSDETNM
VACQVAYSLFHTPTKIARVRESAYLTREELFDNDHIPVDVLISPEQVVTNYIKRLIEHPGSLQVIDFAEGKAQLVAVRAY
YGGPLVGQQLRQIRAHMPNVDTRVAAIFRRDRPITPQGDTVIEADDEVFFIAAKKDIRAVMGELRRIDETNKRVVIAGGG
QIGERLAEAIESRYQVKIIEMNPARCRHLSENLESTVVLQGSASDRDLMLEENIADADIFLALTNDDEANIMSSLLAKRL
GARKVMTIINNPAYVDLVQGGEIDIAISPQLATIGTLLAHVRRGDIVSVHSLRRGAAEAIEAVAHGDSKSSKVVGKAIED
ISLPPGTTIGAIIRDEEVLIAHDDTVIASGDHVILFVVDKKQIRDVEKLFHVGLSFF
>Mature_457_residues
MKIIILGAGQVGGTLAEHLASEANDITVVDTDSERLRDLGDRLDIRTVQGRASLPTVLRQAGADDADMLVAVTNSDETNM
VACQVAYSLFHTPTKIARVRESAYLTREELFDNDHIPVDVLISPEQVVTNYIKRLIEHPGSLQVIDFAEGKAQLVAVRAY
YGGPLVGQQLRQIRAHMPNVDTRVAAIFRRDRPITPQGDTVIEADDEVFFIAAKKDIRAVMGELRRIDETNKRVVIAGGG
QIGERLAEAIESRYQVKIIEMNPARCRHLSENLESTVVLQGSASDRDLMLEENIADADIFLALTNDDEANIMSSLLAKRL
GARKVMTIINNPAYVDLVQGGEIDIAISPQLATIGTLLAHVRRGDIVSVHSLRRGAAEAIEAVAHGDSKSSKVVGKAIED
ISLPPGTTIGAIIRDEEVLIAHDDTVIASGDHVILFVVDKKQIRDVEKLFHVGLSFF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=62.882096069869, Blast_Score=583, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49906; Mature: 49906

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAEHLASEANDITVVDTDSERLRDLGDRLDIRTVQGRASLPTVLRQ
CEEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCEEEECCCCHHHHHHHH
AGADDADMLVAVTNSDETNMVACQVAYSLFHTPTKIARVRESAYLTREELFDNDHIPVDV
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LISPEQVVTNYIKRLIEHPGSLQVIDFAEGKAQLVAVRAYYGGPLVGQQLRQIRAHMPNV
EECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCC
DTRVAAIFRRDRPITPQGDTVIEADDEVFFIAAKKDIRAVMGELRRIDETNKRVVIAGGG
HHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEECCC
QIGERLAEAIESRYQVKIIEMNPARCRHLSENLESTVVLQGSASDRDLMLEENIADADIF
HHHHHHHHHHCCCEEEEEEEECHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCEEE
LALTNDDEANIMSSLLAKRLGARKVMTIINNPAYVDLVQGGEIDIAISPQLATIGTLLAH
EEEECCCHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCEEEEEECCCHHHHHHHHHH
VRRGDIVSVHSLRRGAAEAIEAVAHGDSKSSKVVGKAIEDISLPPGTTIGAIIRDEEVLI
HHCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEE
AHDDTVIASGDHVILFVVDKKQIRDVEKLFHVGLSFF
EECCEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAEHLASEANDITVVDTDSERLRDLGDRLDIRTVQGRASLPTVLRQ
CEEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCEEEECCCCHHHHHHHH
AGADDADMLVAVTNSDETNMVACQVAYSLFHTPTKIARVRESAYLTREELFDNDHIPVDV
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LISPEQVVTNYIKRLIEHPGSLQVIDFAEGKAQLVAVRAYYGGPLVGQQLRQIRAHMPNV
EECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCC
DTRVAAIFRRDRPITPQGDTVIEADDEVFFIAAKKDIRAVMGELRRIDETNKRVVIAGGG
HHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEECCC
QIGERLAEAIESRYQVKIIEMNPARCRHLSENLESTVVLQGSASDRDLMLEENIADADIF
HHHHHHHHHHCCCEEEEEEEECHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCEEE
LALTNDDEANIMSSLLAKRLGARKVMTIINNPAYVDLVQGGEIDIAISPQLATIGTLLAH
EEEECCCHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCEEEEEECCCHHHHHHHHHH
VRRGDIVSVHSLRRGAAEAIEAVAHGDSKSSKVVGKAIEDISLPPGTTIGAIIRDEEVLI
HHCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEE
AHDDTVIASGDHVILFVVDKKQIRDVEKLFHVGLSFF
EECCEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]