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The map label for this gene is ttdR [H]

Identifier: 104779325

GI number: 104779325

Start: 11398

End: 12285

Strand: Reverse

Name: ttdR [H]

Synonym: PSEEN0010

Alternate gene names: 104779325

Gene position: 12285-11398 (Counterclockwise)

Preceding gene: 104779328

Following gene: 104779321

Centisome position: 0.21

GC content: 64.41

Gene sequence:

>888_bases
ATGTTCGACTGGAACGATCTGCGGTTTTTCCTCGAGTTGCAGCGCAGCGGCCGTCTGCTCACCGCCGCCAAGCGCCTCAA
CACCACCCACAGCACCGTGGCCCGGCATATCGAGAGCATCGAAAAGCACCTGGGCACCGCGCTGTTCGTCCAGCATGCCC
AGGGCTACGAACTCACCCCCTCCGGCCAGGCCCTGCTCAAGCACGCCGAAGCGATGGAAAACGTTGCCCTGCTGGCGCAG
GAAGAAATCACCCAGGCCATCACGCCGCTGGGCAAGATTCGCCTGGGGGTGACCGAGGGTATCGGCATCATGTTCTTCAC
CCCGCGCATGAACGCCTTGTTCCAGCGCTACCCGGGGCTCGAAGTGGAATTGGTGGCCGTGCCGCGCTTCGTCAGCATCC
TCAACCGCGAAGCCGAGATCAGCATCCACCTGGAACGCCCCAACGCCGACCTGCTGATCACCCGCAAGCTCACCGACTAC
CGCCTGGCACTCTACGCCAGCCAAGACTACCTGGACCGCGCACCACCGCTGCAAAGCCGCGAGGACCTGGCCCGGCACAG
CTGGATTGGTTACGTCGACGACCTGCTGTTCAGCCAAGAGCTGCTGTTCCTCAACAGCTTCTGCCGAACACCCAACGTGG
TGTTCCGCAGCACCAGCGTGATCGCCCAGCAGCACGCCGCCCAGGCCGGGCTGGGTATCGCCGTGCTGCCCAACTACATG
GCCCGCCACGACCCGAAGCTGGTGCGCGTGCTGCCCAGCGAGACCATCCAGCGCAGCTATTGGATCTGCACCCGCCGCGA
ACTGCACAAGTCGGTACGCCTGCGGGTGGTGTGGGACTATCTGCTGGCGCTGTGCGCCGCCGAGCAGGACGAATTGCTAG
CCGAGTAG

Upstream 100 bases:

>100_bases
CGATGCAGGCACCGCGTTGTCTGGCATCCGCTTCGCGGATGATCGCGGCTAAAGCCGCTCCTACAGCGAAAGGGTCCCCA
TGAACGGCAAAAGGATCAGC

Downstream 100 bases:

>100_bases
CGCCTTGCCGGCCAGCAGCACCGCGGCGCCACACCCCACCACGGCGAACAGCTGTTGCAGGCGCGGGCCGGCCAGCTTGC
CCGCCAGTGGCCTCGCCAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MFDWNDLRFFLELQRSGRLLTAAKRLNTTHSTVARHIESIEKHLGTALFVQHAQGYELTPSGQALLKHAEAMENVALLAQ
EEITQAITPLGKIRLGVTEGIGIMFFTPRMNALFQRYPGLEVELVAVPRFVSILNREAEISIHLERPNADLLITRKLTDY
RLALYASQDYLDRAPPLQSREDLARHSWIGYVDDLLFSQELLFLNSFCRTPNVVFRSTSVIAQQHAAQAGLGIAVLPNYM
ARHDPKLVRVLPSETIQRSYWICTRRELHKSVRLRVVWDYLLALCAAEQDELLAE

Sequences:

>Translated_295_residues
MFDWNDLRFFLELQRSGRLLTAAKRLNTTHSTVARHIESIEKHLGTALFVQHAQGYELTPSGQALLKHAEAMENVALLAQ
EEITQAITPLGKIRLGVTEGIGIMFFTPRMNALFQRYPGLEVELVAVPRFVSILNREAEISIHLERPNADLLITRKLTDY
RLALYASQDYLDRAPPLQSREDLARHSWIGYVDDLLFSQELLFLNSFCRTPNVVFRSTSVIAQQHAAQAGLGIAVLPNYM
ARHDPKLVRVLPSETIQRSYWICTRRELHKSVRLRVVWDYLLALCAAEQDELLAE
>Mature_295_residues
MFDWNDLRFFLELQRSGRLLTAAKRLNTTHSTVARHIESIEKHLGTALFVQHAQGYELTPSGQALLKHAEAMENVALLAQ
EEITQAITPLGKIRLGVTEGIGIMFFTPRMNALFQRYPGLEVELVAVPRFVSILNREAEISIHLERPNADLLITRKLTDY
RLALYASQDYLDRAPPLQSREDLARHSWIGYVDDLLFSQELLFLNSFCRTPNVVFRSTSVIAQQHAAQAGLGIAVLPNYM
ARHDPKLVRVLPSETIQRSYWICTRRELHKSVRLRVVWDYLLALCAAEQDELLAE

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=27.5167785234899, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI145693193, Length=287, Percent_Identity=27.1777003484321, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=27.6094276094276, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=23.2638888888889, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=25.6, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33674; Mature: 33674

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDWNDLRFFLELQRSGRLLTAAKRLNTTHSTVARHIESIEKHLGTALFVQHAQGYELTP
CCCHHHHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCHHEEEECCCCCEECC
SGQALLKHAEAMENVALLAQEEITQAITPLGKIRLGVTEGIGIMFFTPRMNALFQRYPGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCEEEEECCHHHHHHHHCCCC
EVELVAVPRFVSILNREAEISIHLERPNADLLITRKLTDYRLALYASQDYLDRAPPLQSR
EEEEEEHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCEEEEEEECHHHHHCCCCCCCH
EDLARHSWIGYVDDLLFSQELLFLNSFCRTPNVVFRSTSVIAQQHAAQAGLGIAVLPNYM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEECCHHH
ARHDPKLVRVLPSETIQRSYWICTRRELHKSVRLRVVWDYLLALCAAEQDELLAE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MFDWNDLRFFLELQRSGRLLTAAKRLNTTHSTVARHIESIEKHLGTALFVQHAQGYELTP
CCCHHHHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCHHEEEECCCCCEECC
SGQALLKHAEAMENVALLAQEEITQAITPLGKIRLGVTEGIGIMFFTPRMNALFQRYPGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCEEEEECCHHHHHHHHCCCC
EVELVAVPRFVSILNREAEISIHLERPNADLLITRKLTDYRLALYASQDYLDRAPPLQSR
EEEEEEHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCEEEEEEECHHHHHCCCCCCCH
EDLARHSWIGYVDDLLFSQELLFLNSFCRTPNVVFRSTSVIAQQHAAQAGLGIAVLPNYM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEECCHHH
ARHDPKLVRVLPSETIQRSYWICTRRELHKSVRLRVVWDYLLALCAAEQDELLAE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]