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The map label for this gene is zraR [H]

Identifier: 104779321

GI number: 104779321

Start: 6840

End: 8141

Strand: Reverse

Name: zraR [H]

Synonym: PSEEN0005

Alternate gene names: 104779321

Gene position: 8141-6840 (Counterclockwise)

Preceding gene: 104779325

Following gene: NA

Centisome position: 0.14

GC content: 61.29

Gene sequence:

>1302_bases
ATGCTAGCCGCTTCCCATCCTGCGATCTTCGCGCTGGTGTCCTACCTCGAACACGATGTGCTGCCCAGCATCGTGCTGGA
TACTGACTACAACATCCTGGCAGCCAACGCGGCGTACCGTCGCCAGTTTGGCACCGAGGAGCACGCGCCCATCGGCGAAA
AGTGCCATCGAGTCTCGCACCACTATGCCGTCCCTTGCGACCAGGCCGGGGAACATTGTCCGCTGCGCAAGTCACTGGAC
AGCAAGGTGCCCGAGCGCGTTCTCCACATCCATCACACCCCACGCGGGCCTGAACATGTGGATGTGGAACTGCGCCCGAT
CCTCGATGACGAGGGTAGGGTAGTAGCCTTCGTCGAGCGCCTGACCAGCGTCACCCTGGCATCGGCTCAACCTCAACAGC
AAGGGCTGGTTGGCCGAGCACCCGCGTTCAAGGCCGCCGTGGCCAGTTTGCAGCGCGCGGCGCCTGCACAGATTCCGGTA
TTGCTTCAGGGTGAGTCCGGCACTGGCAAGGAACTGTTCGCCCGTGCCTTGCACCTGGGTAGCCCACGCGCCAATGGCCC
CCTGGTGGTGGTGGACTGCACCGGGTTGACCGAGTCGTTGTTCGAGAGTGAATTGTTCGGCTATGAGAAGGGCGCCTTCA
CCGGCGCGACTCAACGCAAGATCGGCCTGGCCGAAGCCGCTCACGGTGGCACCCTGTTCCTCGATGAGATCGGTGAGGTA
CCGCTGGCCATGCAGGTAAAGCTGCTGCGCCTGATCGAGTCCGGCAGCTTCCGCCCGGTCGGCAGCACACGCACGGTCCA
CTCAGATTTTCGCCTGGTCTCGGCCACGCACAAACCACTGAAAGAGATGGCCACTGAAGGGACGTTCCGCGAAGACCTCT
ATTACCGCATCAGTGGATTCCCGATCCGCTTGCCATCACTGCGCGAACGGGTCGAAGACTTGCCACTGCTCTGTGAAAGT
CTGCTGCAACGAATGGCCGGCAAGCAATCGCCAAAAGTTACGGCTGAGGCGCTCGAGCAGCTGAACCTGCACACCTTCCC
AGGCAACATCCGTGAACTCAGGAATATTCTGGAACGCGCCCGGCTGTTCACGGATGACGGTCTGATCCGCCCTGAGCATC
TTCCAGAAGATATGTACCCGGCCGCAAAGCCGGCATGTTCACGAGGGCGGGGCAGGAATGAAATGGCCGACCTGGCCCAT
GCCTTGGAAACCTTCAATGGCTCCCGTAGCGAGTTGGCCGATCATCTGGGGATGAGCGAACGCACGTTGTACCGTCGGCT
GAAGGCGCTGGGCATTTCATAG

Upstream 100 bases:

>100_bases
CTGACAGCCAAAGGTGACAGTTCCTGGCAGTCGACTGTCAGCCGATGGCAGTGTTTGGCAGTCCTTGCTACCCTCGCCAG
GTCCTTCATCTGGTGCTGTC

Downstream 100 bases:

>100_bases
TTCCACGTGGAACATTTGCGTAAGCAAAAAAAAGCCAATCCCTAAGGATTGGCTTTTTTGTACTGCCCGCTAATCAGAAG
TCCAGGTTGGACACCGACAA

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLAASHPAIFALVSYLEHDVLPSIVLDTDYNILAANAAYRRQFGTEEHAPIGEKCHRVSHHYAVPCDQAGEHCPLRKSLD
SKVPERVLHIHHTPRGPEHVDVELRPILDDEGRVVAFVERLTSVTLASAQPQQQGLVGRAPAFKAAVASLQRAAPAQIPV
LLQGESGTGKELFARALHLGSPRANGPLVVVDCTGLTESLFESELFGYEKGAFTGATQRKIGLAEAAHGGTLFLDEIGEV
PLAMQVKLLRLIESGSFRPVGSTRTVHSDFRLVSATHKPLKEMATEGTFREDLYYRISGFPIRLPSLRERVEDLPLLCES
LLQRMAGKQSPKVTAEALEQLNLHTFPGNIRELRNILERARLFTDDGLIRPEHLPEDMYPAAKPACSRGRGRNEMADLAH
ALETFNGSRSELADHLGMSERTLYRRLKALGIS

Sequences:

>Translated_433_residues
MLAASHPAIFALVSYLEHDVLPSIVLDTDYNILAANAAYRRQFGTEEHAPIGEKCHRVSHHYAVPCDQAGEHCPLRKSLD
SKVPERVLHIHHTPRGPEHVDVELRPILDDEGRVVAFVERLTSVTLASAQPQQQGLVGRAPAFKAAVASLQRAAPAQIPV
LLQGESGTGKELFARALHLGSPRANGPLVVVDCTGLTESLFESELFGYEKGAFTGATQRKIGLAEAAHGGTLFLDEIGEV
PLAMQVKLLRLIESGSFRPVGSTRTVHSDFRLVSATHKPLKEMATEGTFREDLYYRISGFPIRLPSLRERVEDLPLLCES
LLQRMAGKQSPKVTAEALEQLNLHTFPGNIRELRNILERARLFTDDGLIRPEHLPEDMYPAAKPACSRGRGRNEMADLAH
ALETFNGSRSELADHLGMSERTLYRRLKALGIS
>Mature_433_residues
MLAASHPAIFALVSYLEHDVLPSIVLDTDYNILAANAAYRRQFGTEEHAPIGEKCHRVSHHYAVPCDQAGEHCPLRKSLD
SKVPERVLHIHHTPRGPEHVDVELRPILDDEGRVVAFVERLTSVTLASAQPQQQGLVGRAPAFKAAVASLQRAAPAQIPV
LLQGESGTGKELFARALHLGSPRANGPLVVVDCTGLTESLFESELFGYEKGAFTGATQRKIGLAEAAHGGTLFLDEIGEV
PLAMQVKLLRLIESGSFRPVGSTRTVHSDFRLVSATHKPLKEMATEGTFREDLYYRISGFPIRLPSLRERVEDLPLLCES
LLQRMAGKQSPKVTAEALEQLNLHTFPGNIRELRNILERARLFTDDGLIRPEHLPEDMYPAAKPACSRGRGRNEMADLAH
ALETFNGSRSELADHLGMSERTLYRRLKALGIS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=307, Percent_Identity=42.9967426710098, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788550, Length=324, Percent_Identity=40.4320987654321, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1789233, Length=367, Percent_Identity=37.874659400545, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.2597402597403, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1788905, Length=306, Percent_Identity=37.9084967320261, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87082117, Length=325, Percent_Identity=37.8461538461538, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=41.692789968652, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1790299, Length=362, Percent_Identity=35.6353591160221, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87082152, Length=266, Percent_Identity=41.3533834586466, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787583, Length=310, Percent_Identity=36.7741935483871, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=44.3965517241379, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789828, Length=289, Percent_Identity=37.3702422145329, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI87081858, Length=292, Percent_Identity=30.8219178082192, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47674; Mature: 47674

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAASHPAIFALVSYLEHDVLPSIVLDTDYNILAANAAYRRQFGTEEHAPIGEKCHRVSH
CCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEECCHHHHHHCCCCCCCCHHHHHHHHHC
HYAVPCDQAGEHCPLRKSLDSKVPERVLHIHHTPRGPEHVDVELRPILDDEGRVVAFVER
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
LTSVTLASAQPQQQGLVGRAPAFKAAVASLQRAAPAQIPVLLQGESGTGKELFARALHLG
HHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCC
SPRANGPLVVVDCTGLTESLFESELFGYEKGAFTGATQRKIGLAEAAHGGTLFLDEIGEV
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHCCC
PLAMQVKLLRLIESGSFRPVGSTRTVHSDFRLVSATHKPLKEMATEGTFREDLYYRISGF
CHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCC
PIRLPSLRERVEDLPLLCESLLQRMAGKQSPKVTAEALEQLNLHTFPGNIRELRNILERA
EEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHH
RLFTDDGLIRPEHLPEDMYPAAKPACSRGRGRNEMADLAHALETFNGSRSELADHLGMSE
HHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHH
RTLYRRLKALGIS
HHHHHHHHHHCCC
>Mature Secondary Structure
MLAASHPAIFALVSYLEHDVLPSIVLDTDYNILAANAAYRRQFGTEEHAPIGEKCHRVSH
CCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEECCHHHHHHCCCCCCCCHHHHHHHHHC
HYAVPCDQAGEHCPLRKSLDSKVPERVLHIHHTPRGPEHVDVELRPILDDEGRVVAFVER
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
LTSVTLASAQPQQQGLVGRAPAFKAAVASLQRAAPAQIPVLLQGESGTGKELFARALHLG
HHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCC
SPRANGPLVVVDCTGLTESLFESELFGYEKGAFTGATQRKIGLAEAAHGGTLFLDEIGEV
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHCCC
PLAMQVKLLRLIESGSFRPVGSTRTVHSDFRLVSATHKPLKEMATEGTFREDLYYRISGF
CHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCC
PIRLPSLRERVEDLPLLCESLLQRMAGKQSPKVTAEALEQLNLHTFPGNIRELRNILERA
EEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHH
RLFTDDGLIRPEHLPEDMYPAAKPACSRGRGRNEMADLAHALETFNGSRSELADHLGMSE
HHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHH
RTLYRRLKALGIS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]