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The map label for this gene is crtI [H]

Identifier: 94986407

GI number: 94986407

Start: 2428786

End: 2430330

Strand: Reverse

Name: crtI [H]

Synonym: Dgeo_2310

Alternate gene names: 94986407

Gene position: 2430330-2428786 (Counterclockwise)

Preceding gene: 94986410

Following gene: 94986406

Centisome position: 98.51

GC content: 69.19

Gene sequence:

>1545_bases
ATGCGGGCTATGCCGGACTTCGACGTTGTGGTGATGGGCGCGGGGCACAACGCGCTGGTGACGGCCGCCTACGCGGCCAA
GGCCGGACTGAAGGTCGGCGTATTTGAGCGGCGGCATCTGGTGGGCGGCGCGGTGAGCACCGAGGAACTCGTCCCCGGTT
ACCGCTTTGACTACGGCGGCAGCGCCCACATCCTGATTCGTATGACGCCGGTGGTGCGCGAGCTGGAACTCTCGCGCCAC
GGCCTGCATTACCTGGAAGTGGACCCGATGTTCCACGCCTCGGACGGCGAGACGCCTTGGTTTGTCTGGCGCGACGCCGA
GCGCACGGCACGGGAGCTGGAGGCCCTGTTTCCCGGCCAGGGCGAGGCGTACCGCCGCTTTCTGGAAGACTGGACGCCCT
TTGCGCGCAGCGTCGCGGACCTCTTCAACTCGGCCCCCGGTCCGCTGGAGCTGGGGAGGATGGCCCTGCGGGGCGGGCAG
GGGAGAGCCTGGCAGGCCCAGCTTCCCCGCATCCTGCGCCCTTACGGCGACGTGGCCCGCGAGTATTTTTCAGAGGAGCG
GGTGCGGGCACCGCTGGTCTGGATGGCGGCCCAGAGTGGCCCGCCCCCCACGGATCCGCTCAGTGCCCCCTTCTTGCTGT
GGCACCCCCTCTACCACGTGGGCGGCGTGGCGCGGCCCAAGGGAGGAAGCGGCGGACTGACCCAGGCCCTGCGCCGGGCC
GTGGAGGCGGGCGGCGGCCAGGTTTTGACCAACGCGCCGGTAAAACGCATCCTGGTGAAAGGTGGCCGGGCGCAGGGCAT
CGAGCTGGCGGGCGGCGAGCGGTACACCGCTCGAGCGGTCGTGTCCGGAACCCACATCCTCGCGACGGCAGGGGCACTGC
CGCCTGAACACGTGCCCGAGGCAGCGCGCAGGGTCCGGGTGGGGGACGGCTTTGGGATGGTGCTGCGGCTCGCCCTTAGC
GAACGGGTGCGCTACCGCCAACACCGTGAGCCGGAAAGCCGGGTGGGGCTGGGCCTGCTGATCAAGCATGAGCGGCAGCT
CCTGCGGGGCTACGGCGAATACTTGGCGGGCGAACCCACCCGCGATCCGCCCCTGGTCGCCATGAGCTTTTCGGCGGTGG
ACGACAGCCTGGCGCCGCCCGGCGGCGAGGTGCTGTGGCTGTGGGCGCAGTATTACCCCTTTGAGCTGGCGTCGGGAACG
TGGGAGAGCCGCCAAGCAGAAGCGCGTGAGAACATTCTGCGGGCCTTTGAACACTACGCCCCTGGGACACGGGACAGCAT
TGTGGGCGAACTGGTGCAGACGCCGCAGTGGCTGGAAAGGGAGCTGGGCCTCTTGCGCGGCAACGTGATGCACCTGGAGA
TGAGTTTTGACCAGATGTTCGCTTTTCGCCCCTGGTTGGGGGCCAGCCAGTACCGGTGGCCGGGCGTGCGGGGCCTTTAC
CTCACCGGCGCGAGCACCCACCCTGGCGGCGGCATCATGGGGGCGTCAGGCAGGAACGCGGCGCGGGTTCTGTTGCGGGA
TCTAACACGCCGGAGGGGGACATGA

Upstream 100 bases:

>100_bases
AACACGATCCGGGGGGGCACGCGGCGACCGAACATGGCCGGAGGGTAGCGCGGGGCGTCTGGCGGATTCCTGACCGTTTC
GGGGGGTGTGGCGTGCCAGC

Downstream 100 bases:

>100_bases
AAGGGGCGGGAGGGGATGGACCGTACAAACCAGTTCAGAGTGCTTGATGGAGGCCGCATGTCCCCTGCCCTCCTGCGCCT
CACCCTCTCTGTCGCCGCCC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MRAMPDFDVVVMGAGHNALVTAAYAAKAGLKVGVFERRHLVGGAVSTEELVPGYRFDYGGSAHILIRMTPVVRELELSRH
GLHYLEVDPMFHASDGETPWFVWRDAERTARELEALFPGQGEAYRRFLEDWTPFARSVADLFNSAPGPLELGRMALRGGQ
GRAWQAQLPRILRPYGDVAREYFSEERVRAPLVWMAAQSGPPPTDPLSAPFLLWHPLYHVGGVARPKGGSGGLTQALRRA
VEAGGGQVLTNAPVKRILVKGGRAQGIELAGGERYTARAVVSGTHILATAGALPPEHVPEAARRVRVGDGFGMVLRLALS
ERVRYRQHREPESRVGLGLLIKHERQLLRGYGEYLAGEPTRDPPLVAMSFSAVDDSLAPPGGEVLWLWAQYYPFELASGT
WESRQAEARENILRAFEHYAPGTRDSIVGELVQTPQWLERELGLLRGNVMHLEMSFDQMFAFRPWLGASQYRWPGVRGLY
LTGASTHPGGGIMGASGRNAARVLLRDLTRRRGT

Sequences:

>Translated_514_residues
MRAMPDFDVVVMGAGHNALVTAAYAAKAGLKVGVFERRHLVGGAVSTEELVPGYRFDYGGSAHILIRMTPVVRELELSRH
GLHYLEVDPMFHASDGETPWFVWRDAERTARELEALFPGQGEAYRRFLEDWTPFARSVADLFNSAPGPLELGRMALRGGQ
GRAWQAQLPRILRPYGDVAREYFSEERVRAPLVWMAAQSGPPPTDPLSAPFLLWHPLYHVGGVARPKGGSGGLTQALRRA
VEAGGGQVLTNAPVKRILVKGGRAQGIELAGGERYTARAVVSGTHILATAGALPPEHVPEAARRVRVGDGFGMVLRLALS
ERVRYRQHREPESRVGLGLLIKHERQLLRGYGEYLAGEPTRDPPLVAMSFSAVDDSLAPPGGEVLWLWAQYYPFELASGT
WESRQAEARENILRAFEHYAPGTRDSIVGELVQTPQWLERELGLLRGNVMHLEMSFDQMFAFRPWLGASQYRWPGVRGLY
LTGASTHPGGGIMGASGRNAARVLLRDLTRRRGT
>Mature_514_residues
MRAMPDFDVVVMGAGHNALVTAAYAAKAGLKVGVFERRHLVGGAVSTEELVPGYRFDYGGSAHILIRMTPVVRELELSRH
GLHYLEVDPMFHASDGETPWFVWRDAERTARELEALFPGQGEAYRRFLEDWTPFARSVADLFNSAPGPLELGRMALRGGQ
GRAWQAQLPRILRPYGDVAREYFSEERVRAPLVWMAAQSGPPPTDPLSAPFLLWHPLYHVGGVARPKGGSGGLTQALRRA
VEAGGGQVLTNAPVKRILVKGGRAQGIELAGGERYTARAVVSGTHILATAGALPPEHVPEAARRVRVGDGFGMVLRLALS
ERVRYRQHREPESRVGLGLLIKHERQLLRGYGEYLAGEPTRDPPLVAMSFSAVDDSLAPPGGEVLWLWAQYYPFELASGT
WESRQAEARENILRAFEHYAPGTRDSIVGELVQTPQWLERELGLLRGNVMHLEMSFDQMFAFRPWLGASQYRWPGVRGLY
LTGASTHPGGGIMGASGRNAARVLLRDLTRRRGT

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=549, Percent_Identity=30.9653916211293, Blast_Score=225, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17540238, Length=538, Percent_Identity=27.3234200743494, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 56671; Mature: 56671

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMPDFDVVVMGAGHNALVTAAYAAKAGLKVGVFERRHLVGGAVSTEELVPGYRFDYGG
CCCCCCCCEEEEECCCCCEEEHHHHHHCCCEEEHHHHHHHHCCCCCHHHHCCCCEECCCC
SAHILIRMTPVVRELELSRHGLHYLEVDPMFHASDGETPWFVWRDAERTARELEALFPGQ
CEEEEEEECHHHHHHHHHHCCCEEEEECCEEECCCCCCCEEEEECHHHHHHHHHHHCCCC
GEAYRRFLEDWTPFARSVADLFNSAPGPLELGRMALRGGQGRAWQAQLPRILRPYGDVAR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EYFSEERVRAPLVWMAAQSGPPPTDPLSAPFLLWHPLYHVGGVARPKGGSGGLTQALRRA
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VEAGGGQVLTNAPVKRILVKGGRAQGIELAGGERYTARAVVSGTHILATAGALPPEHVPE
HHCCCCEEEECCCHHHHHHCCCCCCCEEECCCCCEEEEEEECCCEEEEECCCCCHHHHHH
AARRVRVGDGFGMVLRLALSERVRYRQHREPESRVGLGLLIKHERQLLRGYGEYLAGEPT
HHHHEECCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
RDPPLVAMSFSAVDDSLAPPGGEVLWLWAQYYPFELASGTWESRQAEARENILRAFEHYA
CCCCEEEEEEHHCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHC
PGTRDSIVGELVQTPQWLERELGLLRGNVMHLEMSFDQMFAFRPWLGASQYRWPGVRGLY
CCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCCEEE
LTGASTHPGGGIMGASGRNAARVLLRDLTRRRGT
EECCCCCCCCCEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAMPDFDVVVMGAGHNALVTAAYAAKAGLKVGVFERRHLVGGAVSTEELVPGYRFDYGG
CCCCCCCCEEEEECCCCCEEEHHHHHHCCCEEEHHHHHHHHCCCCCHHHHCCCCEECCCC
SAHILIRMTPVVRELELSRHGLHYLEVDPMFHASDGETPWFVWRDAERTARELEALFPGQ
CEEEEEEECHHHHHHHHHHCCCEEEEECCEEECCCCCCCEEEEECHHHHHHHHHHHCCCC
GEAYRRFLEDWTPFARSVADLFNSAPGPLELGRMALRGGQGRAWQAQLPRILRPYGDVAR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EYFSEERVRAPLVWMAAQSGPPPTDPLSAPFLLWHPLYHVGGVARPKGGSGGLTQALRRA
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VEAGGGQVLTNAPVKRILVKGGRAQGIELAGGERYTARAVVSGTHILATAGALPPEHVPE
HHCCCCEEEECCCHHHHHHCCCCCCCEEECCCCCEEEEEEECCCEEEEECCCCCHHHHHH
AARRVRVGDGFGMVLRLALSERVRYRQHREPESRVGLGLLIKHERQLLRGYGEYLAGEPT
HHHHEECCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
RDPPLVAMSFSAVDDSLAPPGGEVLWLWAQYYPFELASGTWESRQAEARENILRAFEHYA
CCCCEEEEEEHHCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHC
PGTRDSIVGELVQTPQWLERELGLLRGNVMHLEMSFDQMFAFRPWLGASQYRWPGVRGLY
CCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCCEEE
LTGASTHPGGGIMGASGRNAARVLLRDLTRRRGT
EECCCCCCCCCEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2254247 [H]