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The map label for this gene is 94986324

Identifier: 94986324

GI number: 94986324

Start: 2345624

End: 2346886

Strand: Reverse

Name: 94986324

Synonym: Dgeo_2225

Alternate gene names: NA

Gene position: 2346886-2345624 (Counterclockwise)

Preceding gene: 94986325

Following gene: 94986323

Centisome position: 95.12

GC content: 71.34

Gene sequence:

>1263_bases
GTGACGACTGTTGCCGCACCCGGAACCCACGTGTGGACCCTGGAGGGAGGACTGACCGCCGCGTTTGAGCGCCGCCGAGG
GCCGGGCTTCGCACTGGACCTGCGGGTGCCGGTGGGGAGCGCCCACGATCCGGTGGGTCGGGAAGGTTCCGCGGGCGTCT
TGGAGGAGTGGCTCTACAAGGGCGCAGGGGGTCGGAACGCCCGCGCTTTCCAGGATGCGCTGGATGACCTGGGCGTGCGC
CGGGGCGGGGGTGTGGGCCCGGAGGCCACTCGCTTCAGCGTGAGTGGCCTGACGGCGGACCTTCCCGCCGCGCTCGGGTT
GCTGGCGGACCTGCTTCTGCGGCCTGCCCTGCCGCCAGAGGAACTGCCGGTCCTGGCGGATCTCGCCCGGCAGGATCTGG
AGGGGCTGGAGGACAGTCCGCCTGACCTGCTGGCGATCGAAGCGCGGCGGCGGGCCTTTCCCCGTGACCCGGCCTCGCCC
TTCGCGGGCTACGCTCATCCGGCCAGCGGCACAGCCGAGGGGCTTTCGAACCTGACGGCACAGAATCTGCGTGCCTTTCT
CAACCGCTACGGCACACGCGGCAGCGTGCTGGGCCTGGTGGCCGACGCCGATCCCGGGGAGGTGCGCGGCCTGCTGGAAC
GGGCGTTTGCCGGCTGGCACCCCGGCGAGACCGCACCCGTTCCTGCCGACTTCCATCCTGGCCTGCGCGTGCATGTTCCC
CACGCCGAGGCCGAGCAGACACACCTCAGCGTCACCGCGCCGGGTGTCGCGCCGCGCGATCCCGACTGGCTGTCTTGGCA
GGTGGCGCTGATGGCGCTCTCGGGTGGGAGTGCCAGCCGCCTCTTTCATGCAGTCCGCGAGGAACGGGGCTTGGCCTACA
GTGTCAGCGCGGCGCCGATCCTCCTGGGGGGACGGGGTTTCCTGGCCGCCTACGCGGGCAGTACACCCGAGCGCGCGCCC
GAGACGCTGGCTGTGCTGTTGGCTGAACTCGCTCGGCTGCCGCAGGGCCTCACCGAGGCTGAGTTTGAGCGGGCCCGCCG
TGGCCTCACCGCCAGCGTCGTGTTCGGCGCCGAGAGCCTGCGCGCCCGTGCCAGCAGCCTCACGCGTGATCTGGCGGTGT
TTGGGCGGGTGCGCGGCGTGGCCGAACACCGTGCCCAGATTGCGGCCCTCACCCTGGAGCGGGTGAACGCTTTCCTGGCT
GAGTATGACCCTGTCGCACAGGCGACCATCGTGACGCTTGGCCCGGCGGAGGTACAGGCATGA

Upstream 100 bases:

>100_bases
CGCCTGAGCCTGAAGGCGCCCCCACCCCCCGAGCTGCGCCGCGCGGACGAAACCTGACCGGTCTCCCGGTTTTCCCGTTC
GGCGGCGCTACAATCCCCCG

Downstream 100 bases:

>100_bases
CCGTCCGCTGCACCCTCCCGAATGGCCTGACTCTCCTCCTTGAACCCGATGCAGAGGCACAGACTGTGGCTGCCGGCTAT
TTTGTGGCGACCGGGTCACG

Product: peptidase M16-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTTVAAPGTHVWTLEGGLTAAFERRRGPGFALDLRVPVGSAHDPVGREGSAGVLEEWLYKGAGGRNARAFQDALDDLGVR
RGGGVGPEATRFSVSGLTADLPAALGLLADLLLRPALPPEELPVLADLARQDLEGLEDSPPDLLAIEARRRAFPRDPASP
FAGYAHPASGTAEGLSNLTAQNLRAFLNRYGTRGSVLGLVADADPGEVRGLLERAFAGWHPGETAPVPADFHPGLRVHVP
HAEAEQTHLSVTAPGVAPRDPDWLSWQVALMALSGGSASRLFHAVREERGLAYSVSAAPILLGGRGFLAAYAGSTPERAP
ETLAVLLAELARLPQGLTEAEFERARRGLTASVVFGAESLRARASSLTRDLAVFGRVRGVAEHRAQIAALTLERVNAFLA
EYDPVAQATIVTLGPAEVQA

Sequences:

>Translated_420_residues
MTTVAAPGTHVWTLEGGLTAAFERRRGPGFALDLRVPVGSAHDPVGREGSAGVLEEWLYKGAGGRNARAFQDALDDLGVR
RGGGVGPEATRFSVSGLTADLPAALGLLADLLLRPALPPEELPVLADLARQDLEGLEDSPPDLLAIEARRRAFPRDPASP
FAGYAHPASGTAEGLSNLTAQNLRAFLNRYGTRGSVLGLVADADPGEVRGLLERAFAGWHPGETAPVPADFHPGLRVHVP
HAEAEQTHLSVTAPGVAPRDPDWLSWQVALMALSGGSASRLFHAVREERGLAYSVSAAPILLGGRGFLAAYAGSTPERAP
ETLAVLLAELARLPQGLTEAEFERARRGLTASVVFGAESLRARASSLTRDLAVFGRVRGVAEHRAQIAALTLERVNAFLA
EYDPVAQATIVTLGPAEVQA
>Mature_419_residues
TTVAAPGTHVWTLEGGLTAAFERRRGPGFALDLRVPVGSAHDPVGREGSAGVLEEWLYKGAGGRNARAFQDALDDLGVRR
GGGVGPEATRFSVSGLTADLPAALGLLADLLLRPALPPEELPVLADLARQDLEGLEDSPPDLLAIEARRRAFPRDPASPF
AGYAHPASGTAEGLSNLTAQNLRAFLNRYGTRGSVLGLVADADPGEVRGLLERAFAGWHPGETAPVPADFHPGLRVHVPH
AEAEQTHLSVTAPGVAPRDPDWLSWQVALMALSGGSASRLFHAVREERGLAYSVSAAPILLGGRGFLAAYAGSTPERAPE
TLAVLLAELARLPQGLTEAEFERARRGLTASVVFGAESLRARASSLTRDLAVFGRVRGVAEHRAQIAALTLERVNAFLAE
YDPVAQATIVTLGPAEVQA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=429, Percent_Identity=21.9114219114219, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI94538354, Length=431, Percent_Identity=20.6496519721578, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=406, Percent_Identity=19.2118226600985, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=420, Percent_Identity=20.7142857142857, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357875, Length=431, Percent_Identity=20.6496519721578, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646943, Length=431, Percent_Identity=20.6496519721578, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: NA

Molecular weight: Translated: 44141; Mature: 44010

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVAAPGTHVWTLEGGLTAAFERRRGPGFALDLRVPVGSAHDPVGREGSAGVLEEWLYK
CCCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
GAGGRNARAFQDALDDLGVRRGGGVGPEATRFSVSGLTADLPAALGLLADLLLRPALPPE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHH
ELPVLADLARQDLEGLEDSPPDLLAIEARRRAFPRDPASPFAGYAHPASGTAEGLSNLTA
HHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QNLRAFLNRYGTRGSVLGLVADADPGEVRGLLERAFAGWHPGETAPVPADFHPGLRVHVP
HHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECC
HAEAEQTHLSVTAPGVAPRDPDWLSWQVALMALSGGSASRLFHAVREERGLAYSVSAAPI
CCCCCCCEEEEECCCCCCCCCCHHHHEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCEE
LLGGRGFLAAYAGSTPERAPETLAVLLAELARLPQGLTEAEFERARRGLTASVVFGAESL
EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECHHHH
RARASSLTRDLAVFGRVRGVAEHRAQIAALTLERVNAFLAEYDPVAQATIVTLGPAEVQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHCCC
>Mature Secondary Structure 
TTVAAPGTHVWTLEGGLTAAFERRRGPGFALDLRVPVGSAHDPVGREGSAGVLEEWLYK
CCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
GAGGRNARAFQDALDDLGVRRGGGVGPEATRFSVSGLTADLPAALGLLADLLLRPALPPE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHH
ELPVLADLARQDLEGLEDSPPDLLAIEARRRAFPRDPASPFAGYAHPASGTAEGLSNLTA
HHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QNLRAFLNRYGTRGSVLGLVADADPGEVRGLLERAFAGWHPGETAPVPADFHPGLRVHVP
HHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECC
HAEAEQTHLSVTAPGVAPRDPDWLSWQVALMALSGGSASRLFHAVREERGLAYSVSAAPI
CCCCCCCEEEEECCCCCCCCCCHHHHEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCEE
LLGGRGFLAAYAGSTPERAPETLAVLLAELARLPQGLTEAEFERARRGLTASVVFGAESL
EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECHHHH
RARASSLTRDLAVFGRVRGVAEHRAQIAALTLERVNAFLAEYDPVAQATIVTLGPAEVQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA