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The map label for this gene is aphA [H]

Identifier: 94986278

GI number: 94986278

Start: 2296437

End: 2298569

Strand: Reverse

Name: aphA [H]

Synonym: Dgeo_2179

Alternate gene names: 94986278

Gene position: 2298569-2296437 (Counterclockwise)

Preceding gene: 94986279

Following gene: 94986277

Centisome position: 93.16

GC content: 67.51

Gene sequence:

>2133_bases
ATGACCTCCCCTCCTGAACCTGCCCTGCCACCCGCCCTGGCCCACCTGCTGGACGCTGCGGCGGACGCAACCTTCACCCT
GGACCCCGAGGGGCGCATCACTTATGCCAACCACAAGGCGGCGGCCATCGCGGGGCGCAGGCCCGAGGAGGTGCTGGGGC
TGCATCTGGAGCGGGATCTGGGCTATGCCTTTAGCCCCCGCTGGCTGAGTGAGAGCCGCCGTGCGCTGGCGGAAGGGCGT
GCCCGCGAGTACGACGCTTTCAACCCGGCCCTGGGCCGTTGGGTACGGGTTTGTGTGGTGCCGACACCCGCGGGGCTGGC
CGCGCAGATCCGGGATATCATCTTCACCAAGCGCACCGAGGCGCTGCAACAGGTCACGTCGGCCTTGGCCCACACCCGCA
CGCCCGCCGATGTCGTGGACGTTTTGCTGGAGCAGACGCGGGTGGTGGCGGGCGCGTACCTGGCCGCACTCTTTGTGCCA
GGTGCCGACGAGGAACACCTGGAACTGCGTGGGCAGGTGGGCTACAGCCCCGAGCTGCTGCGCCGTTTTGCGCGGGTGCC
GCTGACGCTCCAGATTCCGCTGTGCCGGGCGGCCCGCCTGGGTCAGCCGGTTTTCGCGCAGCAGGCGGATTTCGCCCGTG
ACTTCCCGGACGCTTCTGTGCTGAGTGCGGAGCAGACCCGCAGCCTCGCGGCGCTTCCACTGGAGGTGGAGGAGCGGCTG
TGGGGCGTCCTGGTTCTGAGCTTCGATGAGGACCGGCCCTTGCCCCCCCATGAGCGGGCCTTTCTGCTAAGTCTGGTGGG
ACAGTGCGTGCAGGCCCTCAGTCGCCACGAGACCGAGCAGCGGCTGCGGGTGCAGGCCGACACGCTGAAAACGCTGAATG
CGGTTGGGCGAGCGCTGTCCGCTGAGCTGGACCTCGACCGGCTGGTGCAGGCGGTCACCGATGCGGGGGTGGAGCTGACC
GGTGCGCAGTTCGGCGCGTTCTTCTACAACGTGGTGAACGAGCAGCAGGAGAGTTATACCCTCTATACGCTTTCGGGCGT
GCCGCGGGAGGCCTTTGCCGCCTTTCCGATGCCCCGCAACACGCCGGTCTTCGGCCCCACCTTCAGGGGCGAAGGTGCGT
TCCGTTCCGCCGACATCACCCGCGATCCGCGGTACGGCCACAACCTGCCCTATCGCGGGATGCCCGAAGGCCACCTGCCG
GTGCGCAGCTACCTGGCCGTGCCGGTGGTATCGCGCAGCGGTGAGGTGATCGGCGGTCTGTTCTTCGGGCACGCCAAGCC
GGGCGTCTTTACCGAACGCGCCGAGGAGCTGGCGCTGGGACTCGCCTCACAGACAGCGGTGGCGCTTGACAATGCGCGGC
TGTACGGACAACTTCAGCACAGCCACGCGGACCTCGAACGGCGAGTGGAGGAACGCACCCGGCAGCTGGAGCTGCAGGCG
GCGGAATTGCGGCGCAGCAACGCCGAACTCGAACAGTTCGCCTATGTCGCCTCGCACGACCTGCAGGCCCCGATTCGCGC
CGTGACCAGTTTTGCGGGTTTGGTCAGCCGCAAGTACGCCGCACAGCTCGACGAGCGCGGGCAGGCGTACCTGCGGCAGA
TCGTGGAGAACGGCGAGCACATGAAACGCCTGGTGGACGACCTGCTCGCTTTCTCGCGCCTCCACACGCAGCAGCGTGCA
CCGGAGGCCACCGCGAGCAGTGCTGTTGTGCGCGCGGTGCTGGATCGGCTGCGCCCTGAACTGGAGGCGCTGGACGCCCA
CGTGACGTTAGGCCCGTTGCCCACGGTGCTCGCGGACGCGCCGCAGCTCGATCAACTTTTCCAGAACCTGCTTTCGAACG
CGCTGAAGTACCGCCGGGAGGGTGTGCCGCCCCAGGTATCCATCACGGCCGAGCGGGAAGGCTCCGGCTGGCGCTTTGCC
GTCTCCGACAACGGCATCGGCATCGAGCCGCAGTACTTTGACCGCATCTTTGTGATTTTTCAGCGCCTGCATGGCCGCGA
ACAGTACGAGGGGACCGGGATCGGCCTGGCCGTCTGCAAGAAGATCGTCGAGCGCCACGGTGGGCGGCTGTGGGTGGAAT
CGGCACCGGGGCGGGGATCCACCTTCTTCTTCACGCTGCCGGGCGATTCTTAA

Upstream 100 bases:

>100_bases
CGGGCCTGCGGGTGGGCGACACGCCGCCCGCGCCCGAGCCGCTGATTCTGGACCGCGTGAACTGAGAAGCTGGCTGGCCC
CGCTAGAATGGCCCCGGCCG

Downstream 100 bases:

>100_bases
CCCTGACGTAACCCGCCGCCGTTCGCAGGCGCAGCGCGGGGATGTTACGCTCGAGTCATGCGGACAGCCGTCCTGATCTT
CATTCTGGTTCTTGCCGTGC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MTSPPEPALPPALAHLLDAAADATFTLDPEGRITYANHKAAAIAGRRPEEVLGLHLERDLGYAFSPRWLSESRRALAEGR
AREYDAFNPALGRWVRVCVVPTPAGLAAQIRDIIFTKRTEALQQVTSALAHTRTPADVVDVLLEQTRVVAGAYLAALFVP
GADEEHLELRGQVGYSPELLRRFARVPLTLQIPLCRAARLGQPVFAQQADFARDFPDASVLSAEQTRSLAALPLEVEERL
WGVLVLSFDEDRPLPPHERAFLLSLVGQCVQALSRHETEQRLRVQADTLKTLNAVGRALSAELDLDRLVQAVTDAGVELT
GAQFGAFFYNVVNEQQESYTLYTLSGVPREAFAAFPMPRNTPVFGPTFRGEGAFRSADITRDPRYGHNLPYRGMPEGHLP
VRSYLAVPVVSRSGEVIGGLFFGHAKPGVFTERAEELALGLASQTAVALDNARLYGQLQHSHADLERRVEERTRQLELQA
AELRRSNAELEQFAYVASHDLQAPIRAVTSFAGLVSRKYAAQLDERGQAYLRQIVENGEHMKRLVDDLLAFSRLHTQQRA
PEATASSAVVRAVLDRLRPELEALDAHVTLGPLPTVLADAPQLDQLFQNLLSNALKYRREGVPPQVSITAEREGSGWRFA
VSDNGIGIEPQYFDRIFVIFQRLHGREQYEGTGIGLAVCKKIVERHGGRLWVESAPGRGSTFFFTLPGDS

Sequences:

>Translated_710_residues
MTSPPEPALPPALAHLLDAAADATFTLDPEGRITYANHKAAAIAGRRPEEVLGLHLERDLGYAFSPRWLSESRRALAEGR
AREYDAFNPALGRWVRVCVVPTPAGLAAQIRDIIFTKRTEALQQVTSALAHTRTPADVVDVLLEQTRVVAGAYLAALFVP
GADEEHLELRGQVGYSPELLRRFARVPLTLQIPLCRAARLGQPVFAQQADFARDFPDASVLSAEQTRSLAALPLEVEERL
WGVLVLSFDEDRPLPPHERAFLLSLVGQCVQALSRHETEQRLRVQADTLKTLNAVGRALSAELDLDRLVQAVTDAGVELT
GAQFGAFFYNVVNEQQESYTLYTLSGVPREAFAAFPMPRNTPVFGPTFRGEGAFRSADITRDPRYGHNLPYRGMPEGHLP
VRSYLAVPVVSRSGEVIGGLFFGHAKPGVFTERAEELALGLASQTAVALDNARLYGQLQHSHADLERRVEERTRQLELQA
AELRRSNAELEQFAYVASHDLQAPIRAVTSFAGLVSRKYAAQLDERGQAYLRQIVENGEHMKRLVDDLLAFSRLHTQQRA
PEATASSAVVRAVLDRLRPELEALDAHVTLGPLPTVLADAPQLDQLFQNLLSNALKYRREGVPPQVSITAEREGSGWRFA
VSDNGIGIEPQYFDRIFVIFQRLHGREQYEGTGIGLAVCKKIVERHGGRLWVESAPGRGSTFFFTLPGDS
>Mature_709_residues
TSPPEPALPPALAHLLDAAADATFTLDPEGRITYANHKAAAIAGRRPEEVLGLHLERDLGYAFSPRWLSESRRALAEGRA
REYDAFNPALGRWVRVCVVPTPAGLAAQIRDIIFTKRTEALQQVTSALAHTRTPADVVDVLLEQTRVVAGAYLAALFVPG
ADEEHLELRGQVGYSPELLRRFARVPLTLQIPLCRAARLGQPVFAQQADFARDFPDASVLSAEQTRSLAALPLEVEERLW
GVLVLSFDEDRPLPPHERAFLLSLVGQCVQALSRHETEQRLRVQADTLKTLNAVGRALSAELDLDRLVQAVTDAGVELTG
AQFGAFFYNVVNEQQESYTLYTLSGVPREAFAAFPMPRNTPVFGPTFRGEGAFRSADITRDPRYGHNLPYRGMPEGHLPV
RSYLAVPVVSRSGEVIGGLFFGHAKPGVFTERAEELALGLASQTAVALDNARLYGQLQHSHADLERRVEERTRQLELQAA
ELRRSNAELEQFAYVASHDLQAPIRAVTSFAGLVSRKYAAQLDERGQAYLRQIVENGEHMKRLVDDLLAFSRLHTQQRAP
EATASSAVVRAVLDRLRPELEALDAHVTLGPLPTVLADAPQLDQLFQNLLSNALKYRREGVPPQVSITAEREGSGWRFAV
SDNGIGIEPQYFDRIFVIFQRLHGREQYEGTGIGLAVCKKIVERHGGRLWVESAPGRGSTFFFTLPGDS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=31.6279069767442, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=29.0836653386454, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=29.9595141700405, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=29.2134831460674, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=291, Percent_Identity=25.7731958762887, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=26.953125, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=24.6913580246914, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=27.3542600896861, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=278, Percent_Identity=28.4172661870504, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=25.5707762557078, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788393, Length=173, Percent_Identity=31.2138728323699, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=26.6393442622951, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=219, Percent_Identity=26.4840182648402, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78362; Mature: 78231

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPPEPALPPALAHLLDAAADATFTLDPEGRITYANHKAAAIAGRRPEEVLGLHLERDL
CCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEECCCCHHHHCCCCCHHHHCCHHHHCC
GYAFSPRWLSESRRALAEGRAREYDAFNPALGRWVRVCVVPTPAGLAAQIRDIIFTKRTE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHH
ALQQVTSALAHTRTPADVVDVLLEQTRVVAGAYLAALFVPGADEEHLELRGQVGYSPELL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHH
RRFARVPLTLQIPLCRAARLGQPVFAQQADFARDFPDASVLSAEQTRSLAALPLEVEERL
HHHHCCCEEEECCHHHHHHCCCCHHHHHHHHHHCCCCCHHHCHHHHHCHHCCCHHHHHHC
WGVLVLSFDEDRPLPPHERAFLLSLVGQCVQALSRHETEQRLRVQADTLKTLNAVGRALS
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AELDLDRLVQAVTDAGVELTGAQFGAFFYNVVNEQQESYTLYTLSGVPREAFAAFPMPRN
HCCCHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCCCCCC
TPVFGPTFRGEGAFRSADITRDPRYGHNLPYRGMPEGHLPVRSYLAVPVVSRSGEVIGGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCCCEEEEE
FFGHAKPGVFTERAEELALGLASQTAVALDNARLYGQLQHSHADLERRVEERTRQLELQA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELRRSNAELEQFAYVASHDLQAPIRAVTSFAGLVSRKYAAQLDERGQAYLRQIVENGEH
HHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MKRLVDDLLAFSRLHTQQRAPEATASSAVVRAVLDRLRPELEALDAHVTLGPLPTVLADA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHCCCEECCCCHHHHCCC
PQLDQLFQNLLSNALKYRREGVPPQVSITAEREGSGWRFAVSDNGIGIEPQYFDRIFVIF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHH
QRLHGREQYEGTGIGLAVCKKIVERHGGRLWVESAPGRGSTFFFTLPGDS
HHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCC
>Mature Secondary Structure 
TSPPEPALPPALAHLLDAAADATFTLDPEGRITYANHKAAAIAGRRPEEVLGLHLERDL
CCCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEECCCCHHHHCCCCCHHHHCCHHHHCC
GYAFSPRWLSESRRALAEGRAREYDAFNPALGRWVRVCVVPTPAGLAAQIRDIIFTKRTE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHH
ALQQVTSALAHTRTPADVVDVLLEQTRVVAGAYLAALFVPGADEEHLELRGQVGYSPELL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHH
RRFARVPLTLQIPLCRAARLGQPVFAQQADFARDFPDASVLSAEQTRSLAALPLEVEERL
HHHHCCCEEEECCHHHHHHCCCCHHHHHHHHHHCCCCCHHHCHHHHHCHHCCCHHHHHHC
WGVLVLSFDEDRPLPPHERAFLLSLVGQCVQALSRHETEQRLRVQADTLKTLNAVGRALS
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AELDLDRLVQAVTDAGVELTGAQFGAFFYNVVNEQQESYTLYTLSGVPREAFAAFPMPRN
HCCCHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCCCCCC
TPVFGPTFRGEGAFRSADITRDPRYGHNLPYRGMPEGHLPVRSYLAVPVVSRSGEVIGGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCCCEEEEE
FFGHAKPGVFTERAEELALGLASQTAVALDNARLYGQLQHSHADLERRVEERTRQLELQA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELRRSNAELEQFAYVASHDLQAPIRAVTSFAGLVSRKYAAQLDERGQAYLRQIVENGEH
HHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MKRLVDDLLAFSRLHTQQRAPEATASSAVVRAVLDRLRPELEALDAHVTLGPLPTVLADA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHCCCEECCCCHHHHCCC
PQLDQLFQNLLSNALKYRREGVPPQVSITAEREGSGWRFAVSDNGIGIEPQYFDRIFVIF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHH
QRLHGREQYEGTGIGLAVCKKIVERHGGRLWVESAPGRGSTFFFTLPGDS
HHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]