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The map label for this gene is aphA [H]

Identifier: 94986247

GI number: 94986247

Start: 2259220

End: 2261532

Strand: Reverse

Name: aphA [H]

Synonym: Dgeo_2148

Alternate gene names: 94986247

Gene position: 2261532-2259220 (Counterclockwise)

Preceding gene: 94986248

Following gene: 94986246

Centisome position: 91.66

GC content: 66.97

Gene sequence:

>2313_bases
ATGCCGGAACAGGCGCCTCCATCCCCTCTTGGTGCTCTTGCGGGCGCGGATTTGTTGCCGCTTCTCACGGCGCTGCCCGA
TCCGGTGCTGCTGCTGGGTGAGGAGGTGACGTGGCTCAATGCTGCGGCGCGCGAGCGCCTGGGCGAACCCCCCGCGGCGG
GGGCATGGCAGGCTCTGTTTCCGCCTGAGCCGGCGCGCTTGCTGACGCTGGCCCAGGCGCGGGCTGCGGCGGGAGAAACA
GTGCGTGAGAGCGTGACGCTGCCCGGCAGCCGCGCGCCCGTCCTCGCCACCCTCACCCCCGCTGGGCCGGGCCAAGTACT
GCTGCATCTGCGCGACACGCGGCATCCGCTGGAGGTGGCCGAGGAGTTGATCGACGGCCTGGGCCTGGGAATGCTGGTGC
AGGCCGCAGATGGCCGGGTGCTGTCGGCCAACGTGGCTGGGCAGGGCCTGCTGGGCCTGAGCCTCGCGCAGATGACCGGG
CAGGTTCCCGCTGACACCCGTTGGCGCGTCATTCGCCCGGATGGACAGCCCTTCGCGCCAGAGGCGCTGCCCATGTTTCG
CGCGCTCGAGACCGGGGAAGTCCAGCGGAACGTGCTGGCGGGCGTGGTGATTCCGAGGGAGGAGGGCGGCGAGGAGACCC
GCTGGATGAACGTGACGGCCTTGCCCCGCCATGCTCCCGGCGTGGTCCGGCCCAAGCAGGTCACCACCGTTTTCGCCGAT
GTGACTGAGGAGCAGCGGCTGCGTCAGCAGATGCAGTTCAGCGAGGAACGCTACCGCTCACTCGTGGAGGCGACCTCGCA
GATCGTGTGGGTGACCACGGCGGAGGGTGAGCTGCTGGGCGAGCAACCCACCTGGTCCGCCTTCACCGGGCAGACCGAGG
CGGAATACCGTGGGTCGGGCTGGGTCGAGGCCCTGCACCCCGACGACCGGGCCGGGGCGCTGGCGGCGTGGCAGCAGGCA
GTTCAGTCCCGCATTCCCTACCAGACCGAGTACCGCTTGCGTCGCGCCGACGGTGTCTATGTGCCGATGCAGGCGCGCGG
TGTGGCGGTGACCAACCCCGACGGCAGCGTGCGCGAGTGGGTCGGAGTCAATGAGGATCTCAGCGCGGTCAAGGCTGCAG
AAGATCATCTGCGGGCGCTGAATGCCACCTTGGAAGAGCGGGTGGCGGCGCGCACCCAAGAACTGGCCGATCTGACGCGC
TTTTCCACCCTGCTGCTGAATGCCGCCGGCGAGGGGATTTTTGGACTGGACGCTTCCGGCCGCACGACCTTTGCCAATCC
TGCTGCTGCACACATCCTGGGATACAGCGTAGAGCGCCTGATTGGTTCGCTCCAGCACGAGCTGATTCATCACCACCATC
CGGATGGCCGTCCCTATCCAGTGGAGGCGTGTCCGATCTACCAAACGCTGCAAGACGGTCAGGTTCGGCGCCGTGAGGGC
GAAGTCTTTTGGCATGCTCGGGGTGAACCTGTGCCGGTGGCCTATGTCGTTTCGCCCACCCACGGACCCGGAGGAGAGGT
GACGGGCGCGGTGGTGATGTTCCAAGACGTGACCGAGCGCCAGCGGGCGCAGGCGGCCCTCGAGGAGGCCATCACCAACC
TTCAGCGCAGCAATGCCGAACTGGAGCAGTTTGCCTACGTGGCCAGCCACGACCTCCAAGAGCCGCTGCGAACGGTGGGC
AGCTACGCCGAGCTGTTGGCCCGACGCTACCAGGGGCAGCTCGATCCGCGCGCCGACCAGTACCTGGCATTCATGCAGGA
CGCGGTCGAACGGATGCGCAGCCTGATTCAGGACCTGTTGGGCTTTGCGCGGGTGGGCCGCATGGATACTGGGCTGCAGC
CTGTCCAGCTGGAGGATGTGCTGCGCCAAGCTGCACAAAACGTCCAGGGCACGCTGGAGGCGACCGGCGCCACCCTGAGT
TGGGACACGCCGCAGACCGTCTGGGGTCATCCTGGCCTGTTGGTGCAGCTTTTTACCAACCTGATCGGCAATGGGCTGAA
GTTTGCCCGTGCCGGGGTTCCGCCTGAGGTGCACGTAACGGCGCACCAGGAGGGCCAGCAGGTGCGGATCAAGGTGCAAG
ACAATGGCATCGGGATCGCCCCCGAATACCATGAACGGGTGTTCGCGATTTTCCAGCGGCTCAACCGCCGAGAAGCCTAT
CCCGGCAACGGCATCGGGCTGGCGATCTGCCGCAAGATCGTTGAGCAGCATGGCGGCTCCATCTCGCTCACATCGGTTCC
CGGTGAGGGGACGACCTTTCACCTGACACTGCCCCTTCCGCCCGTTCCGTCCCGCTTCGGAACCACCCCCTAA

Upstream 100 bases:

>100_bases
GAACCTGCGGGCCAAACTGCGCGACCTCGACGGGTATGGTCTGCTGCGGACCGTGCGCGGCGTCGGCTATGCGCTGCGCG
GCTGATCCAGAGAGGAACTG

Downstream 100 bases:

>100_bases
CCCATATGCCCCCTACCGAATCCCTGATTTCTTCTCAACCCCTGATCGAAATTCTGCTTGTCGAGGACAGCGAACCCGAC
GTGCTGCTCACCCGGGAAGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MPEQAPPSPLGALAGADLLPLLTALPDPVLLLGEEVTWLNAAARERLGEPPAAGAWQALFPPEPARLLTLAQARAAAGET
VRESVTLPGSRAPVLATLTPAGPGQVLLHLRDTRHPLEVAEELIDGLGLGMLVQAADGRVLSANVAGQGLLGLSLAQMTG
QVPADTRWRVIRPDGQPFAPEALPMFRALETGEVQRNVLAGVVIPREEGGEETRWMNVTALPRHAPGVVRPKQVTTVFAD
VTEEQRLRQQMQFSEERYRSLVEATSQIVWVTTAEGELLGEQPTWSAFTGQTEAEYRGSGWVEALHPDDRAGALAAWQQA
VQSRIPYQTEYRLRRADGVYVPMQARGVAVTNPDGSVREWVGVNEDLSAVKAAEDHLRALNATLEERVAARTQELADLTR
FSTLLLNAAGEGIFGLDASGRTTFANPAAAHILGYSVERLIGSLQHELIHHHHPDGRPYPVEACPIYQTLQDGQVRRREG
EVFWHARGEPVPVAYVVSPTHGPGGEVTGAVVMFQDVTERQRAQAALEEAITNLQRSNAELEQFAYVASHDLQEPLRTVG
SYAELLARRYQGQLDPRADQYLAFMQDAVERMRSLIQDLLGFARVGRMDTGLQPVQLEDVLRQAAQNVQGTLEATGATLS
WDTPQTVWGHPGLLVQLFTNLIGNGLKFARAGVPPEVHVTAHQEGQQVRIKVQDNGIGIAPEYHERVFAIFQRLNRREAY
PGNGIGLAICRKIVEQHGGSISLTSVPGEGTTFHLTLPLPPVPSRFGTTP

Sequences:

>Translated_770_residues
MPEQAPPSPLGALAGADLLPLLTALPDPVLLLGEEVTWLNAAARERLGEPPAAGAWQALFPPEPARLLTLAQARAAAGET
VRESVTLPGSRAPVLATLTPAGPGQVLLHLRDTRHPLEVAEELIDGLGLGMLVQAADGRVLSANVAGQGLLGLSLAQMTG
QVPADTRWRVIRPDGQPFAPEALPMFRALETGEVQRNVLAGVVIPREEGGEETRWMNVTALPRHAPGVVRPKQVTTVFAD
VTEEQRLRQQMQFSEERYRSLVEATSQIVWVTTAEGELLGEQPTWSAFTGQTEAEYRGSGWVEALHPDDRAGALAAWQQA
VQSRIPYQTEYRLRRADGVYVPMQARGVAVTNPDGSVREWVGVNEDLSAVKAAEDHLRALNATLEERVAARTQELADLTR
FSTLLLNAAGEGIFGLDASGRTTFANPAAAHILGYSVERLIGSLQHELIHHHHPDGRPYPVEACPIYQTLQDGQVRRREG
EVFWHARGEPVPVAYVVSPTHGPGGEVTGAVVMFQDVTERQRAQAALEEAITNLQRSNAELEQFAYVASHDLQEPLRTVG
SYAELLARRYQGQLDPRADQYLAFMQDAVERMRSLIQDLLGFARVGRMDTGLQPVQLEDVLRQAAQNVQGTLEATGATLS
WDTPQTVWGHPGLLVQLFTNLIGNGLKFARAGVPPEVHVTAHQEGQQVRIKVQDNGIGIAPEYHERVFAIFQRLNRREAY
PGNGIGLAICRKIVEQHGGSISLTSVPGEGTTFHLTLPLPPVPSRFGTTP
>Mature_769_residues
PEQAPPSPLGALAGADLLPLLTALPDPVLLLGEEVTWLNAAARERLGEPPAAGAWQALFPPEPARLLTLAQARAAAGETV
RESVTLPGSRAPVLATLTPAGPGQVLLHLRDTRHPLEVAEELIDGLGLGMLVQAADGRVLSANVAGQGLLGLSLAQMTGQ
VPADTRWRVIRPDGQPFAPEALPMFRALETGEVQRNVLAGVVIPREEGGEETRWMNVTALPRHAPGVVRPKQVTTVFADV
TEEQRLRQQMQFSEERYRSLVEATSQIVWVTTAEGELLGEQPTWSAFTGQTEAEYRGSGWVEALHPDDRAGALAAWQQAV
QSRIPYQTEYRLRRADGVYVPMQARGVAVTNPDGSVREWVGVNEDLSAVKAAEDHLRALNATLEERVAARTQELADLTRF
STLLLNAAGEGIFGLDASGRTTFANPAAAHILGYSVERLIGSLQHELIHHHHPDGRPYPVEACPIYQTLQDGQVRRREGE
VFWHARGEPVPVAYVVSPTHGPGGEVTGAVVMFQDVTERQRAQAALEEAITNLQRSNAELEQFAYVASHDLQEPLRTVGS
YAELLARRYQGQLDPRADQYLAFMQDAVERMRSLIQDLLGFARVGRMDTGLQPVQLEDVLRQAAQNVQGTLEATGATLSW
DTPQTVWGHPGLLVQLFTNLIGNGLKFARAGVPPEVHVTAHQEGQQVRIKVQDNGIGIAPEYHERVFAIFQRLNRREAYP
GNGIGLAICRKIVEQHGGSISLTSVPGEGTTFHLTLPLPPVPSRFGTTP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=387, Percent_Identity=25.5813953488372, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1786912, Length=218, Percent_Identity=34.8623853211009, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994928, Length=420, Percent_Identity=24.5238095238095, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=26.1029411764706, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789149, Length=268, Percent_Identity=27.9850746268657, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788381, Length=487, Percent_Identity=23.6139630390144, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788393, Length=280, Percent_Identity=27.8571428571429, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=24.8148148148148, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=29.1479820627803, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=26.3374485596708, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=27.0042194092827, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=28.4552845528455, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790300, Length=382, Percent_Identity=23.2984293193717, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=261, Percent_Identity=26.8199233716475, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=25.3521126760563, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=27.1111111111111, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83767; Mature: 83636

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQAPPSPLGALAGADLLPLLTALPDPVLLLGEEVTWLNAAARERLGEPPAAGAWQALF
CCCCCCCCCHHHHHCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCC
PPEPARLLTLAQARAAAGETVRESVTLPGSRAPVLATLTPAGPGQVLLHLRDTRHPLEVA
CCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHH
EELIDGLGLGMLVQAADGRVLSANVAGQGLLGLSLAQMTGQVPADTRWRVIRPDGQPFAP
HHHHHHCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
EALPMFRALETGEVQRNVLAGVVIPREEGGEETRWMNVTALPRHAPGVVRPKQVTTVFAD
HHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
VTEEQRLRQQMQFSEERYRSLVEATSQIVWVTTAEGELLGEQPTWSAFTGQTEAEYRGSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WVEALHPDDRAGALAAWQQAVQSRIPYQTEYRLRRADGVYVPMQARGVAVTNPDGSVREW
CEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHECCCCEEEEEECCCEEEECCCCCHHHH
VGVNEDLSAVKAAEDHLRALNATLEERVAARTQELADLTRFSTLLLNAAGEGIFGLDASG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
RTTFANPAAAHILGYSVERLIGSLQHELIHHHHPDGRPYPVEACPIYQTLQDGQVRRREG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHEECCC
EVFWHARGEPVPVAYVVSPTHGPGGEVTGAVVMFQDVTERQRAQAALEEAITNLQRSNAE
CEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCH
LEQFAYVASHDLQEPLRTVGSYAELLARRYQGQLDPRADQYLAFMQDAVERMRSLIQDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GFARVGRMDTGLQPVQLEDVLRQAAQNVQGTLEATGATLSWDTPQTVWGHPGLLVQLFTN
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCHHHHHHHHH
LIGNGLKFARAGVPPEVHVTAHQEGQQVRIKVQDNGIGIAPEYHERVFAIFQRLNRREAY
HHCCCCEEHHCCCCCCEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
PGNGIGLAICRKIVEQHGGSISLTSVPGEGTTFHLTLPLPPVPSRFGTTP
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PEQAPPSPLGALAGADLLPLLTALPDPVLLLGEEVTWLNAAARERLGEPPAAGAWQALF
CCCCCCCCHHHHHCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCC
PPEPARLLTLAQARAAAGETVRESVTLPGSRAPVLATLTPAGPGQVLLHLRDTRHPLEVA
CCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHH
EELIDGLGLGMLVQAADGRVLSANVAGQGLLGLSLAQMTGQVPADTRWRVIRPDGQPFAP
HHHHHHCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
EALPMFRALETGEVQRNVLAGVVIPREEGGEETRWMNVTALPRHAPGVVRPKQVTTVFAD
HHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
VTEEQRLRQQMQFSEERYRSLVEATSQIVWVTTAEGELLGEQPTWSAFTGQTEAEYRGSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WVEALHPDDRAGALAAWQQAVQSRIPYQTEYRLRRADGVYVPMQARGVAVTNPDGSVREW
CEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHECCCCEEEEEECCCEEEECCCCCHHHH
VGVNEDLSAVKAAEDHLRALNATLEERVAARTQELADLTRFSTLLLNAAGEGIFGLDASG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
RTTFANPAAAHILGYSVERLIGSLQHELIHHHHPDGRPYPVEACPIYQTLQDGQVRRREG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHEECCC
EVFWHARGEPVPVAYVVSPTHGPGGEVTGAVVMFQDVTERQRAQAALEEAITNLQRSNAE
CEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCH
LEQFAYVASHDLQEPLRTVGSYAELLARRYQGQLDPRADQYLAFMQDAVERMRSLIQDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GFARVGRMDTGLQPVQLEDVLRQAAQNVQGTLEATGATLSWDTPQTVWGHPGLLVQLFTN
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCHHHHHHHHH
LIGNGLKFARAGVPPEVHVTAHQEGQQVRIKVQDNGIGIAPEYHERVFAIFQRLNRREAY
HHCCCCEEHHCCCCCCEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
PGNGIGLAICRKIVEQHGGSISLTSVPGEGTTFHLTLPLPPVPSRFGTTP
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]