Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 94986234

GI number: 94986234

Start: 2247488

End: 2249701

Strand: Reverse

Name: dnaX [H]

Synonym: Dgeo_2135

Alternate gene names: 94986234

Gene position: 2249701-2247488 (Counterclockwise)

Preceding gene: 94986238

Following gene: 94986233

Centisome position: 91.18

GC content: 69.83

Gene sequence:

>2214_bases
ATGAGTGCCCTCTACCAACGCGCCCGACCGATCAACTGGGACCAGGTGGTCGGCCAAGAACACGTCAAAGACGTGCTGAA
AGCGGCGCTGGAGCAAGGGCGTGTGGGCCATGCTTACCTCTTTTCGGGGCCGCGCGGTGTCGGCAAAACCACGACCGCCC
GCCTAATTGCCATGACCGCCAACTGCACCGGGCCGAGCCCGAAGCCCTGTGGCGAATGCGAATCGTGCCTGGCGGTCAGG
AACGGCTCGCATCCCGACGTGCTCGAGATCGACGCGGCCTCCAATAACTCGGTTGACGACGTGCGCGATCTGCGCGAGAA
GGTGGGGCTTGCAGCGATGCGCGGCGGCAAGAAAATCTACATTCTTGACGAGGCGCACATGATGTCGCGGGCGGCCTTTA
ACGCCCTGCTCAAGACGCTGGAGGAGCCGCCCGCCCACGTGATCTTTATCCTGGCGACCACCGAGCCGGAAAAGATCATC
CCGACCATCCTCTCGCGCTGCCAGCATTACCGCTTTCGTCGCCTGACACCGGAGGAAATCGCCGGAAAACTGGCGGACCT
GGCGGAACGCGAAGGCGTGCGGGCCGAGCCGGAGGCCCTGAATCTGATTGGGCGCCTCGCTGACGGAGCGATGCGCGACG
GCGAGAGCCTGCTGGAGCGGATGCTGGCGGCGGGGACAGCGGTGACCCGGGTGAGCGTGGAGGAGGCGTTGGGCCTGCCG
CCGAGCGAGCGCGTGCGCGGCATCGCCGCGGCCCTTGTGCAGGGCGACGCGGGCATGGCTCTCACCGGAGCCGCCGAGCT
GTACCGAGCAGGTTTCGCGGCACGCACCATCGTGGAGGGGCTGGTCGCGGCCTGTGCGGAGGCCCTGCACGCTGAGCTGG
GTTTGGAGGGCGCGGGACTGGAGGGCGCAGATGTGCCCCGCTTGCTTCGGCTTCAGGCCGCGCTCGACGAGCAGGAGGCC
CGCTTTGCCCGCTCCGCCGACCTGCTGAGCCTGGAACTGGCCCTGACCCACGCGCTGCTTGCCGCCGATGCTGGTGGCGG
TGGGGGGATGGTGGGCGCGGCGGCTCCGGCCAGCCTTCCCGCCGACGTGGCGCAGCGCCTCAACCGCCTAGAAAAGGAAG
TGGCGAGCCTACGGATGAGCGGGACCCGGCCCGCTCCAGCCAACGAGGTGCCGGCCTTTGAGCCGGGCAAACGCCGGGGA
GGGCCTGCCGGGGAAGCTCCAGCCCGTGCCGAGACGCCGGCGCCGATGCCCGCCGCCGTGCAGGGGAGCTGGGACGATGT
GGTGAAAGCCGCGAGCATGCAGCTCAAGGCGTTTATCAAGACGGCGCAAAAGCACAGCGAGCCGGGATACGTCAGCCTCA
CCTATGAGGCGCGCTGGAAGTTCCATGCCCGGCAGGTCATGGACAAATGGGACGAACTGAGCGCCCACGTCCTGAAAGTC
TTTGGACCGGTGACGTTGGAAGTCATTCCACCGGAAGGCCAGGGCCGCAAAGCTCAGCTCGGTGGGCGCGGCCCCGACGG
GGGTGGGGGAGGGCCGGCTCCTGCTGTCCCTTTCGGCACGGCTGCCCCTCTCGCGCAGAGTCGGCCCACGCCTGAGATTC
CCGCCTTTGAACCCGCTGCTCGGTCCCGGGCGTCGCGTGGGCCGGCGTTCGCGCCCCTGAAGACAGCGCCGCCCGAACGT
GCCGCCGCTCCGCCACTGCCGACCGGTGCGGTCACCGCTCCCCTCGACGCCCCCGCGCTCCGTCCCGCCCCGCCTCCCAG
TCCCGACGACGTGGCCCCAGCGCCGCTGCCGGACGCTGCTCCCTGGGAGGACCAGGCCGCGGAGCTCCCGCCCCCACCGG
CGGATGCTCAGGCCGGAGACCGCCTGCCTCTGCCCGGCGCGTCTCGCGAGCTGTACCTGGCCGAACCGATCACCGAGGAA
CCCGACTGGGAAGCCATCGGTGGTGAGGTGGAAGGGCCGGTGCCCACACTGGAGGATGCACCCTTCGCGGATGCCGTGCC
GGCCCGCCCGGCCACAACGCCCCGGGCGGAGGCCCGCCCCACGGCCCAAGCGGAGGCCGCGCCGCCCACCCGTCCCGGTG
ATATCCGCGCCCACCCGATGTATGAGGAGATCAAGAAACGGTTCTCGGGCCGCGTCCGCGAGATCGGCAAAAACCGCAAG
CCCCACGCCAGCGCCGCCAGTGAGGAGAGCGAGGGTGAGGACGTGGAGGCGTAG

Upstream 100 bases:

>100_bases
GCTTCAGGGTGAGTGGTCGGTGGTTGGTGGTGCGTGAGTTGGGCACCTGTCTTGCGCCACGCGCGGCCCGCCTCCCACGT
TCCAGGTCGAGGGTGCGCCG

Downstream 100 bases:

>100_bases
TTCTCCCCCCGCGACATGAAGGCCGGAGCTTCACGATCGCTCCTGATCTCCTGCGCTACCCTGCCTCCACACCGTGAAGA
CCTCTTCTTTCCTCCCTGCG

Product: DNA polymerase III, subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 736

Protein sequence:

>737_residues
MSALYQRARPINWDQVVGQEHVKDVLKAALEQGRVGHAYLFSGPRGVGKTTTARLIAMTANCTGPSPKPCGECESCLAVR
NGSHPDVLEIDAASNNSVDDVRDLREKVGLAAMRGGKKIYILDEAHMMSRAAFNALLKTLEEPPAHVIFILATTEPEKII
PTILSRCQHYRFRRLTPEEIAGKLADLAEREGVRAEPEALNLIGRLADGAMRDGESLLERMLAAGTAVTRVSVEEALGLP
PSERVRGIAAALVQGDAGMALTGAAELYRAGFAARTIVEGLVAACAEALHAELGLEGAGLEGADVPRLLRLQAALDEQEA
RFARSADLLSLELALTHALLAADAGGGGGMVGAAAPASLPADVAQRLNRLEKEVASLRMSGTRPAPANEVPAFEPGKRRG
GPAGEAPARAETPAPMPAAVQGSWDDVVKAASMQLKAFIKTAQKHSEPGYVSLTYEARWKFHARQVMDKWDELSAHVLKV
FGPVTLEVIPPEGQGRKAQLGGRGPDGGGGGPAPAVPFGTAAPLAQSRPTPEIPAFEPAARSRASRGPAFAPLKTAPPER
AAAPPLPTGAVTAPLDAPALRPAPPPSPDDVAPAPLPDAAPWEDQAAELPPPPADAQAGDRLPLPGASRELYLAEPITEE
PDWEAIGGEVEGPVPTLEDAPFADAVPARPATTPRAEARPTAQAEAAPPTRPGDIRAHPMYEEIKKRFSGRVREIGKNRK
PHASAASEESEGEDVEA

Sequences:

>Translated_737_residues
MSALYQRARPINWDQVVGQEHVKDVLKAALEQGRVGHAYLFSGPRGVGKTTTARLIAMTANCTGPSPKPCGECESCLAVR
NGSHPDVLEIDAASNNSVDDVRDLREKVGLAAMRGGKKIYILDEAHMMSRAAFNALLKTLEEPPAHVIFILATTEPEKII
PTILSRCQHYRFRRLTPEEIAGKLADLAEREGVRAEPEALNLIGRLADGAMRDGESLLERMLAAGTAVTRVSVEEALGLP
PSERVRGIAAALVQGDAGMALTGAAELYRAGFAARTIVEGLVAACAEALHAELGLEGAGLEGADVPRLLRLQAALDEQEA
RFARSADLLSLELALTHALLAADAGGGGGMVGAAAPASLPADVAQRLNRLEKEVASLRMSGTRPAPANEVPAFEPGKRRG
GPAGEAPARAETPAPMPAAVQGSWDDVVKAASMQLKAFIKTAQKHSEPGYVSLTYEARWKFHARQVMDKWDELSAHVLKV
FGPVTLEVIPPEGQGRKAQLGGRGPDGGGGGPAPAVPFGTAAPLAQSRPTPEIPAFEPAARSRASRGPAFAPLKTAPPER
AAAPPLPTGAVTAPLDAPALRPAPPPSPDDVAPAPLPDAAPWEDQAAELPPPPADAQAGDRLPLPGASRELYLAEPITEE
PDWEAIGGEVEGPVPTLEDAPFADAVPARPATTPRAEARPTAQAEAAPPTRPGDIRAHPMYEEIKKRFSGRVREIGKNRK
PHASAASEESEGEDVEA
>Mature_736_residues
SALYQRARPINWDQVVGQEHVKDVLKAALEQGRVGHAYLFSGPRGVGKTTTARLIAMTANCTGPSPKPCGECESCLAVRN
GSHPDVLEIDAASNNSVDDVRDLREKVGLAAMRGGKKIYILDEAHMMSRAAFNALLKTLEEPPAHVIFILATTEPEKIIP
TILSRCQHYRFRRLTPEEIAGKLADLAEREGVRAEPEALNLIGRLADGAMRDGESLLERMLAAGTAVTRVSVEEALGLPP
SERVRGIAAALVQGDAGMALTGAAELYRAGFAARTIVEGLVAACAEALHAELGLEGAGLEGADVPRLLRLQAALDEQEAR
FARSADLLSLELALTHALLAADAGGGGGMVGAAAPASLPADVAQRLNRLEKEVASLRMSGTRPAPANEVPAFEPGKRRGG
PAGEAPARAETPAPMPAAVQGSWDDVVKAASMQLKAFIKTAQKHSEPGYVSLTYEARWKFHARQVMDKWDELSAHVLKVF
GPVTLEVIPPEGQGRKAQLGGRGPDGGGGGPAPAVPFGTAAPLAQSRPTPEIPAFEPAARSRASRGPAFAPLKTAPPERA
AAPPLPTGAVTAPLDAPALRPAPPPSPDDVAPAPLPDAAPWEDQAAELPPPPADAQAGDRLPLPGASRELYLAEPITEEP
DWEAIGGEVEGPVPTLEDAPFADAVPARPATTPRAEARPTAQAEAAPPTRPGDIRAHPMYEEIKKRFSGRVREIGKNRKP
HASAASEESEGEDVEA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=287, Percent_Identity=28.2229965156794, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI31881687, Length=287, Percent_Identity=28.2229965156794, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI31563534, Length=297, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI6677723, Length=264, Percent_Identity=26.5151515151515, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI194306571, Length=266, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI194306567, Length=266, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI194306569, Length=183, Percent_Identity=30.0546448087432, Blast_Score=74, Evalue=7e-13,
Organism=Escherichia coli, GI1786676, Length=268, Percent_Identity=45.5223880597015, Blast_Score=232, Evalue=8e-62,
Organism=Escherichia coli, GI1787341, Length=150, Percent_Identity=38.6666666666667, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71986063, Length=288, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541988, Length=279, Percent_Identity=27.9569892473118, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17554730, Length=223, Percent_Identity=27.8026905829596, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322528, Length=297, Percent_Identity=28.2828282828283, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324039, Length=287, Percent_Identity=27.5261324041812, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324478, Length=279, Percent_Identity=26.5232974910394, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17647857, Length=286, Percent_Identity=28.3216783216783, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI18859927, Length=223, Percent_Identity=30.4932735426009, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19921076, Length=256, Percent_Identity=26.171875, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 77377; Mature: 77246

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALYQRARPINWDQVVGQEHVKDVLKAALEQGRVGHAYLFSGPRGVGKTTTARLIAMTA
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEEEEE
NCTGPSPKPCGECESCLAVRNGSHPDVLEIDAASNNSVDDVRDLREKVGLAAMRGGKKIY
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEE
ILDEAHMMSRAAFNALLKTLEEPPAHVIFILATTEPEKIIPTILSRCQHYRFRRLTPEEI
EECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHH
AGKLADLAEREGVRAEPEALNLIGRLADGAMRDGESLLERMLAAGTAVTRVSVEEALGLP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHEEEHHHHHCCC
PSERVRGIAAALVQGDAGMALTGAAELYRAGFAARTIVEGLVAACAEALHAELGLEGAGL
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGADVPRLLRLQAALDEQEARFARSADLLSLELALTHALLAADAGGGGGMVGAAAPASLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ADVAQRLNRLEKEVASLRMSGTRPAPANEVPAFEPGKRRGGPAGEAPARAETPAPMPAAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QGSWDDVVKAASMQLKAFIKTAQKHSEPGYVSLTYEARWKFHARQVMDKWDELSAHVLKV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
FGPVTLEVIPPEGQGRKAQLGGRGPDGGGGGPAPAVPFGTAAPLAQSRPTPEIPAFEPAA
HCCEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHH
RSRASRGPAFAPLKTAPPERAAAPPLPTGAVTAPLDAPALRPAPPPSPDDVAPAPLPDAA
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PWEDQAAELPPPPADAQAGDRLPLPGASRELYLAEPITEEPDWEAIGGEVEGPVPTLEDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHCCCCCCCCCCCCCCC
PFADAVPARPATTPRAEARPTAQAEAAPPTRPGDIRAHPMYEEIKKRFSGRVREIGKNRK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PHASAASEESEGEDVEA
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SALYQRARPINWDQVVGQEHVKDVLKAALEQGRVGHAYLFSGPRGVGKTTTARLIAMTA
CCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEEEEE
NCTGPSPKPCGECESCLAVRNGSHPDVLEIDAASNNSVDDVRDLREKVGLAAMRGGKKIY
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEE
ILDEAHMMSRAAFNALLKTLEEPPAHVIFILATTEPEKIIPTILSRCQHYRFRRLTPEEI
EECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHH
AGKLADLAEREGVRAEPEALNLIGRLADGAMRDGESLLERMLAAGTAVTRVSVEEALGLP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHEEEHHHHHCCC
PSERVRGIAAALVQGDAGMALTGAAELYRAGFAARTIVEGLVAACAEALHAELGLEGAGL
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGADVPRLLRLQAALDEQEARFARSADLLSLELALTHALLAADAGGGGGMVGAAAPASLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ADVAQRLNRLEKEVASLRMSGTRPAPANEVPAFEPGKRRGGPAGEAPARAETPAPMPAAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QGSWDDVVKAASMQLKAFIKTAQKHSEPGYVSLTYEARWKFHARQVMDKWDELSAHVLKV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
FGPVTLEVIPPEGQGRKAQLGGRGPDGGGGGPAPAVPFGTAAPLAQSRPTPEIPAFEPAA
HCCEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHH
RSRASRGPAFAPLKTAPPERAAAPPLPTGAVTAPLDAPALRPAPPPSPDDVAPAPLPDAA
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PWEDQAAELPPPPADAQAGDRLPLPGASRELYLAEPITEEPDWEAIGGEVEGPVPTLEDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHCCCCCCCCCCCCCCC
PFADAVPARPATTPRAEARPTAQAEAAPPTRPGDIRAHPMYEEIKKRFSGRVREIGKNRK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PHASAASEESEGEDVEA
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]