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The map label for this gene is wecB [H]

Identifier: 94985395

GI number: 94985395

Start: 1373633

End: 1374790

Strand: Reverse

Name: wecB [H]

Synonym: Dgeo_1294

Alternate gene names: 94985395

Gene position: 1374790-1373633 (Counterclockwise)

Preceding gene: 94985396

Following gene: 94985394

Centisome position: 55.72

GC content: 70.9

Gene sequence:

>1158_bases
ATGACCGATCTCGCCCGCCCTTCCCAGTCCAAACGCATCGTTCTCGCTTTCGGCACCCGGCCCGAGGCCACCAAAATGGC
CCCGGTCTACGCGGCCATCGCGCGGCAGCCTGGTCTCACGCCGCTGATCCTCTCCACCGGTCAGCAGCGCCAGATGCTCG
ACGAGGCGCTGGCCGTCTTTGGTCTGACCCCCGATGAGGACCTGAACGTGATGACCGACCGCCAGACCCTGGCCGAACTC
ACCGGGCGGATCGTGCCCCAGGCCGGGCGCAAGCTGCGCGAGCTGGGCGCGGACATGGTGCTGGTGCACGGCGATACCAC
CACCTCCTTCTGCGTGGCTCTGAGCGCCTTTTACGAGGGCATCCCGGTGGGACACGTCGAGGCGGGGCTGCGCAGCGGCA
ACATGCGGGAACCCTTCCCCGAGGAGGCCAACCGCCGCCTGACGGGGGTGCTCACCACCCTCGATTTCGCGCCCACACCG
GGCAGCCGGGCCAACCTGCGGCGCGAGGGCAAGGCGGAGGAGGGCATCTTCGTGACCGGGCAGACGGCGGTCGACGCGGT
GCGCGAGGTGGCGGGCCGGGTGCCGCTGCGTCCCGAGTGGCAAGCCAGGCTGGACGCCGGACAGCGCCTGGTGACCGTCA
CCATGCACCGCCGTGAGAACCTGCCGGTGATGGCCCAGATGGCGCAGGCGCTGGCGGACGTGGCCCGCGCCCACCCGGAC
ACCCATTTTGTGTACCCCGTCCACCTGAACCCCGCCGTGCAGGAGGCGGTGCGCCCGGCCCTCGGTCAGCTCCCCAACTT
CGAGCTCACCGAACCGCTCGATTACGCCCAGATGGCCCCCCTGATGGCGGCCTCTACGCTGCTTGCCACCGACAGCGGCG
GCTTGCAGGAGGAGGGGGCGGCGCTGGGCGTGCCCGTCGCGGTGCTGCGCAACGTGACTGAGCGGCCCGAGGGGGTGGAG
GCGGGCGTCCTGGTCCTGGCTGGCAATGACCCCGAGCAGATGCGCACCGTGCTCAATGGCCTGCTGGACGACGAGGCGGG
GCTGGCCCGCATGCGCACCGCGCGCAATCCCTATGGGGACGGGCAGGCGTCTGGGCGCATCGCACAGGCCATCGCCTGGT
TCTTCGGGTTGGGCGAACGGCCGGCCGACTGGTCGTGA

Upstream 100 bases:

>100_bases
CTCTGGTCTGGGCGCAGGTTGATGGCGGGCAAAGCCGCGGCTTCTGGCGTAGGCGCGTCACCTGCGGTGCCTGGACCGCG
GCTCTGCTACCGTGACCCGG

Downstream 100 bases:

>100_bases
AGCGCAAAGAGGCGCTCTCTCCTGTGTCTGACGTGACCGAAGTGTCGTCTTCCCAGCTCCTCCCCGCCCGGCACTATGCC
GTCGTGCTCAATCCCAGCGC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTDLARPSQSKRIVLAFGTRPEATKMAPVYAAIARQPGLTPLILSTGQQRQMLDEALAVFGLTPDEDLNVMTDRQTLAEL
TGRIVPQAGRKLRELGADMVLVHGDTTTSFCVALSAFYEGIPVGHVEAGLRSGNMREPFPEEANRRLTGVLTTLDFAPTP
GSRANLRREGKAEEGIFVTGQTAVDAVREVAGRVPLRPEWQARLDAGQRLVTVTMHRRENLPVMAQMAQALADVARAHPD
THFVYPVHLNPAVQEAVRPALGQLPNFELTEPLDYAQMAPLMAASTLLATDSGGLQEEGAALGVPVAVLRNVTERPEGVE
AGVLVLAGNDPEQMRTVLNGLLDDEAGLARMRTARNPYGDGQASGRIAQAIAWFFGLGERPADWS

Sequences:

>Translated_385_residues
MTDLARPSQSKRIVLAFGTRPEATKMAPVYAAIARQPGLTPLILSTGQQRQMLDEALAVFGLTPDEDLNVMTDRQTLAEL
TGRIVPQAGRKLRELGADMVLVHGDTTTSFCVALSAFYEGIPVGHVEAGLRSGNMREPFPEEANRRLTGVLTTLDFAPTP
GSRANLRREGKAEEGIFVTGQTAVDAVREVAGRVPLRPEWQARLDAGQRLVTVTMHRRENLPVMAQMAQALADVARAHPD
THFVYPVHLNPAVQEAVRPALGQLPNFELTEPLDYAQMAPLMAASTLLATDSGGLQEEGAALGVPVAVLRNVTERPEGVE
AGVLVLAGNDPEQMRTVLNGLLDDEAGLARMRTARNPYGDGQASGRIAQAIAWFFGLGERPADWS
>Mature_384_residues
TDLARPSQSKRIVLAFGTRPEATKMAPVYAAIARQPGLTPLILSTGQQRQMLDEALAVFGLTPDEDLNVMTDRQTLAELT
GRIVPQAGRKLRELGADMVLVHGDTTTSFCVALSAFYEGIPVGHVEAGLRSGNMREPFPEEANRRLTGVLTTLDFAPTPG
SRANLRREGKAEEGIFVTGQTAVDAVREVAGRVPLRPEWQARLDAGQRLVTVTMHRRENLPVMAQMAQALADVARAHPDT
HFVYPVHLNPAVQEAVRPALGQLPNFELTEPLDYAQMAPLMAASTLLATDSGGLQEEGAALGVPVAVLRNVTERPEGVEA
GVLVLAGNDPEQMRTVLNGLLDDEAGLARMRTARNPYGDGQASGRIAQAIAWFFGLGERPADWS

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=368, Percent_Identity=46.7391304347826, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41491; Mature: 41360

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLARPSQSKRIVLAFGTRPEATKMAPVYAAIARQPGLTPLILSTGQQRQMLDEALAVF
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
GLTPDEDLNVMTDRQTLAELTGRIVPQAGRKLRELGADMVLVHGDTTTSFCVALSAFYEG
CCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCC
IPVGHVEAGLRSGNMREPFPEEANRRLTGVLTTLDFAPTPGSRANLRREGKAEEGIFVTG
CCCCHHHHHCCCCCCCCCCCHHHCCHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
QTAVDAVREVAGRVPLRPEWQARLDAGQRLVTVTMHRRENLPVMAQMAQALADVARAHPD
HHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
THFVYPVHLNPAVQEAVRPALGQLPNFELTEPLDYAQMAPLMAASTLLATDSGGLQEEGA
CEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
ALGVPVAVLRNVTERPEGVEAGVLVLAGNDPEQMRTVLNGLLDDEAGLARMRTARNPYGD
CCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
GQASGRIAQAIAWFFGLGERPADWS
CCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDLARPSQSKRIVLAFGTRPEATKMAPVYAAIARQPGLTPLILSTGQQRQMLDEALAVF
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
GLTPDEDLNVMTDRQTLAELTGRIVPQAGRKLRELGADMVLVHGDTTTSFCVALSAFYEG
CCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCC
IPVGHVEAGLRSGNMREPFPEEANRRLTGVLTTLDFAPTPGSRANLRREGKAEEGIFVTG
CCCCHHHHHCCCCCCCCCCCHHHCCHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
QTAVDAVREVAGRVPLRPEWQARLDAGQRLVTVTMHRRENLPVMAQMAQALADVARAHPD
HHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
THFVYPVHLNPAVQEAVRPALGQLPNFELTEPLDYAQMAPLMAASTLLATDSGGLQEEGA
CEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
ALGVPVAVLRNVTERPEGVEAGVLVLAGNDPEQMRTVLNGLLDDEAGLARMRTARNPYGD
CCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
GQASGRIAQAIAWFFGLGERPADWS
CCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]