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The map label for this gene is aroE [H]

Identifier: 94985372

GI number: 94985372

Start: 1351688

End: 1352770

Strand: Reverse

Name: aroE [H]

Synonym: Dgeo_1271

Alternate gene names: 94985372

Gene position: 1352770-1351688 (Counterclockwise)

Preceding gene: 94985378

Following gene: 94985371

Centisome position: 54.83

GC content: 68.05

Gene sequence:

>1083_bases
GTGACTCCTTGGGTGCGTTGCTGTGCGCCGAAACGCACTCTCCCCCCAGAGCGGTTCTCTGGAGGGAGTCGGGAAACGAA
AGAGACATTCGGCTCCTCTATTCTCTGCCGTAGGGGCCAAGGAAGACGTGGGGCACTCCACAATCGCGCGGAAACTCTGA
GGAAAGGCTCAAGCCTCAGGTTTGGCACTCTGGCCCCGGTAGCTGTCCGCGGGCCGAGGCTCAACAGTACACTTGAGCGC
GTGAATCACGGCGTCACTCCTTCCGGCAGGCCCGCTGCGGGGCTAATGCGCGCTTTCCTGTACGCCGATCCCGCTGCGCA
TTCGCTGTCTCCGGCCATGCACCGCGCGGCCTTTGCCTGGGCGGGGGTACAGGGTGACTATACGGCGGTGCGGGTGCCCC
CCGCCGATCTCCCTGCCGCTCTCGCCCGTCTGCGGCAAACCGGCGTGTTGGGCGCCAACCTCAGCCTGCCGCACAAGGAG
GCCGCGCTCGCGCATCTGGATGAGCTCTCGGTCTCGGCGCGTGCGATCGGCGCGGTGAATACCGTCATCCACCGGGAGGG
CAGGTTGATCGGCGACAACACCGACGCGCCCGGTCTGCTGGCGGCCTTAGAGGGGGCACAGGTGGGTTCGGGTGTGGCGG
TCGTGTTGGGCGCTGGGGGGGCGGCACGCGCGGCGGTCTGGGCGTTGCGTTCGCAGGCGTGGGACGTGCGGGTGGTGAAC
CGCACTCCGGGAAAGGCGCAAGCCCTCACGCGCGACCTGGGCGGTCTGGCGCAATCCGCTGACGCGGTGCCGTGGGCCGC
GGTGACCCTGCTCGTGAACGCTTCCAGTGCCGGACTGGAGGCCCCCGCTGAAACACCGTTGCCAGACTTCGACTTCACCG
TCCTGCCCCCCAATGCCCTGGTCTACGACATGGTCTACCAGCCGCGCGAGACACGCCTGCTGCGTGAGGCCCGTCAAGCG
GGGATCCGCGCGGAAAACGGCCTCTCGATGCTGGCGCACCAGGCCCGGCTGGCGTTTCTCGCTTGGACCGGCGCAGACGT
GCCGGTCGGCGTCTTTCTGGCCGCCCTGGAGGACTTGCGTTGA

Upstream 100 bases:

>100_bases
CGCAAAGGCTTCGCGCTGGTTGGCCAGCTGCACCGTGGCGGTGCTGTTCGCGGCAGAAGAGGGGGTGGAGGTGGGCTGGC
CGGGGGTACGTTCTGTCAAT

Downstream 100 bases:

>100_bases
TGCGTGCACTCCACCGCCAGCAGCGGATTTCGTTGGCCGTGCTCGTGCTCGTGCTGCTGCTGAGCGTTTTGGCCGCCCTG
TTGCTCCACCGCTTTGTGGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTPWVRCCAPKRTLPPERFSGGSRETKETFGSSILCRRGQGRRGALHNRAETLRKGSSLRFGTLAPVAVRGPRLNSTLER
VNHGVTPSGRPAAGLMRAFLYADPAAHSLSPAMHRAAFAWAGVQGDYTAVRVPPADLPAALARLRQTGVLGANLSLPHKE
AALAHLDELSVSARAIGAVNTVIHREGRLIGDNTDAPGLLAALEGAQVGSGVAVVLGAGGAARAAVWALRSQAWDVRVVN
RTPGKAQALTRDLGGLAQSADAVPWAAVTLLVNASSAGLEAPAETPLPDFDFTVLPPNALVYDMVYQPRETRLLREARQA
GIRAENGLSMLAHQARLAFLAWTGADVPVGVFLAALEDLR

Sequences:

>Translated_360_residues
MTPWVRCCAPKRTLPPERFSGGSRETKETFGSSILCRRGQGRRGALHNRAETLRKGSSLRFGTLAPVAVRGPRLNSTLER
VNHGVTPSGRPAAGLMRAFLYADPAAHSLSPAMHRAAFAWAGVQGDYTAVRVPPADLPAALARLRQTGVLGANLSLPHKE
AALAHLDELSVSARAIGAVNTVIHREGRLIGDNTDAPGLLAALEGAQVGSGVAVVLGAGGAARAAVWALRSQAWDVRVVN
RTPGKAQALTRDLGGLAQSADAVPWAAVTLLVNASSAGLEAPAETPLPDFDFTVLPPNALVYDMVYQPRETRLLREARQA
GIRAENGLSMLAHQARLAFLAWTGADVPVGVFLAALEDLR
>Mature_359_residues
TPWVRCCAPKRTLPPERFSGGSRETKETFGSSILCRRGQGRRGALHNRAETLRKGSSLRFGTLAPVAVRGPRLNSTLERV
NHGVTPSGRPAAGLMRAFLYADPAAHSLSPAMHRAAFAWAGVQGDYTAVRVPPADLPAALARLRQTGVLGANLSLPHKEA
ALAHLDELSVSARAIGAVNTVIHREGRLIGDNTDAPGLLAALEGAQVGSGVAVVLGAGGAARAAVWALRSQAWDVRVVNR
TPGKAQALTRDLGGLAQSADAVPWAAVTLLVNASSAGLEAPAETPLPDFDFTVLPPNALVYDMVYQPRETRLLREARQAG
IRAENGLSMLAHQARLAFLAWTGADVPVGVFLAALEDLR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=273, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789675, Length=253, Percent_Identity=36.3636363636364, Blast_Score=125, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=282, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 37926; Mature: 37795

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPWVRCCAPKRTLPPERFSGGSRETKETFGSSILCRRGQGRRGALHNRAETLRKGSSLR
CCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCCCC
FGTLAPVAVRGPRLNSTLERVNHGVTPSGRPAAGLMRAFLYADPAAHSLSPAMHRAAFAW
CCCCCCEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHH
AGVQGDYTAVRVPPADLPAALARLRQTGVLGANLSLPHKEAALAHLDELSVSARAIGAVN
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TVIHREGRLIGDNTDAPGLLAALEGAQVGSGVAVVLGAGGAARAAVWALRSQAWDVRVVN
HHHHHCCEEECCCCCCCHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEE
RTPGKAQALTRDLGGLAQSADAVPWAAVTLLVNASSAGLEAPAETPLPDFDFTVLPPNAL
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCE
VYDMVYQPRETRLLREARQAGIRAENGLSMLAHQARLAFLAWTGADVPVGVFLAALEDLR
EEHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TPWVRCCAPKRTLPPERFSGGSRETKETFGSSILCRRGQGRRGALHNRAETLRKGSSLR
CCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCCCC
FGTLAPVAVRGPRLNSTLERVNHGVTPSGRPAAGLMRAFLYADPAAHSLSPAMHRAAFAW
CCCCCCEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHH
AGVQGDYTAVRVPPADLPAALARLRQTGVLGANLSLPHKEAALAHLDELSVSARAIGAVN
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TVIHREGRLIGDNTDAPGLLAALEGAQVGSGVAVVLGAGGAARAAVWALRSQAWDVRVVN
HHHHHCCEEECCCCCCCHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEE
RTPGKAQALTRDLGGLAQSADAVPWAAVTLLVNASSAGLEAPAETPLPDFDFTVLPPNAL
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCE
VYDMVYQPRETRLLREARQAGIRAENGLSMLAHQARLAFLAWTGADVPVGVFLAALEDLR
EEHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA