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The map label for this gene is yhdH [H]

Identifier: 94985330

GI number: 94985330

Start: 1308319

End: 1309347

Strand: Reverse

Name: yhdH [H]

Synonym: Dgeo_1229

Alternate gene names: 94985330

Gene position: 1309347-1308319 (Counterclockwise)

Preceding gene: 94985331

Following gene: 94985329

Centisome position: 53.07

GC content: 69.87

Gene sequence:

>1029_bases
ATGGCCCAGTCACGCCCAAGTTTGCCCGAGCCTCAACGTCCCGAACACTTTCGTGCCCTGCGCGCCGTCAAGGACGAGAC
CGGCGTGCGGCCTGAGTTTCAGACCCTCACTCTTGCCGATCTGCCGGAAGGCGAGGTGCTGGTGCGTGTCACCCACTCCA
GCCTGAACTACAAAGACGGCCTGGCGGTCGCGGGCAGACCCGGTGTGCTTAAGGCTTACCCGATGACGCCCGGCATTGAC
CTGGCGGGGACCGTTGTGGAGGACCAGACCGGGACGTACCGGCCGGGCGACGCAGTCCTGCTGACCGGCTGGGGCATTGG
CGAGCGTCAGGACGGGGGATACGCCGAGTACGCGCGGGTGAAGGCAGCCTGGTTGGTGCCGCTCCCGGAAGGAACCGACG
CGCAGTGGGCCATGAGCGTGGGTACGGCGGGCTTCACGGCGATGCTGGCGGTGATGGCCCTGGAGGAACACGGCGTCACC
CCCGGGAGCGGCGAGGTGCTGGTGACGGGTGCGGCGGGCGGTGTGGGCAGCACTGCCGTCGCTCTGCTTGCCGCCGCCGG
CCATTCCGTCACCGCCAGCACGGGCCGCCGCGAGGAGGAGGACTATCTGCGCTCCCTCGGTGCCGCCAACATCATTGGCC
GTGAGGAATTGCCCGCGCTGAAGCGGCCGCTGGAAAAGGAACGCTGGGCGGGCGTGGTCGACAGTGTGGGGGGGGATACC
TTGGCCGGTGCGCTCGCGAGCACCCGTACCCACGGCGCGGTTGCGGCCTGCGGGCTGGCCGGTGGCAGCGGGCTCAACAC
CACGGTTTTTCCCTTCATCCTGCGGGGCGTGAACTTGCTTGGGATCGACTCGGTGACCTGCCCCACCGAGCGGCGCCGCG
CGGCCTGGGCAAGGCTAGCGCGCGACCTGCCCGCCGCCAAACTCGCAGGTGTGACGCAGCTTCGCCCCCTCAGCGACGTA
CCCGCGCTCGCGCAGGAGATTCTGGCGGGGCGGGTGCGGGGCCGGACCGTGATCGACGTGACCCGCTGA

Upstream 100 bases:

>100_bases
CTAGGTTGTACGGCGGTGATGTACTGCGGTGGTGACGCCGCGATCGGGGGACCGGCGGGGTAGGCTAGAACCGCAACCCA
GCTTGTCCAGGAGGTTTCCC

Downstream 100 bases:

>100_bases
GCGCTGTGTTGCATTTCGTGTCCCGCGCGGGGACTATCCCCTACATTGGGGCCGTCATGAACAGTCTGCTGCGTTTCGTG
CTGCCCGCTGCCGCCCTCGC

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAQSRPSLPEPQRPEHFRALRAVKDETGVRPEFQTLTLADLPEGEVLVRVTHSSLNYKDGLAVAGRPGVLKAYPMTPGID
LAGTVVEDQTGTYRPGDAVLLTGWGIGERQDGGYAEYARVKAAWLVPLPEGTDAQWAMSVGTAGFTAMLAVMALEEHGVT
PGSGEVLVTGAAGGVGSTAVALLAAAGHSVTASTGRREEEDYLRSLGAANIIGREELPALKRPLEKERWAGVVDSVGGDT
LAGALASTRTHGAVAACGLAGGSGLNTTVFPFILRGVNLLGIDSVTCPTERRRAAWARLARDLPAAKLAGVTQLRPLSDV
PALAQEILAGRVRGRTVIDVTR

Sequences:

>Translated_342_residues
MAQSRPSLPEPQRPEHFRALRAVKDETGVRPEFQTLTLADLPEGEVLVRVTHSSLNYKDGLAVAGRPGVLKAYPMTPGID
LAGTVVEDQTGTYRPGDAVLLTGWGIGERQDGGYAEYARVKAAWLVPLPEGTDAQWAMSVGTAGFTAMLAVMALEEHGVT
PGSGEVLVTGAAGGVGSTAVALLAAAGHSVTASTGRREEEDYLRSLGAANIIGREELPALKRPLEKERWAGVVDSVGGDT
LAGALASTRTHGAVAACGLAGGSGLNTTVFPFILRGVNLLGIDSVTCPTERRRAAWARLARDLPAAKLAGVTQLRPLSDV
PALAQEILAGRVRGRTVIDVTR
>Mature_341_residues
AQSRPSLPEPQRPEHFRALRAVKDETGVRPEFQTLTLADLPEGEVLVRVTHSSLNYKDGLAVAGRPGVLKAYPMTPGIDL
AGTVVEDQTGTYRPGDAVLLTGWGIGERQDGGYAEYARVKAAWLVPLPEGTDAQWAMSVGTAGFTAMLAVMALEEHGVTP
GSGEVLVTGAAGGVGSTAVALLAAAGHSVTASTGRREEEDYLRSLGAANIIGREELPALKRPLEKERWAGVVDSVGGDTL
AGALASTRTHGAVAACGLAGGSGLNTTVFPFILRGVNLLGIDSVTCPTERRRAAWARLARDLPAAKLAGVTQLRPLSDVP
ALAQEILAGRVRGRTVIDVTR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239676, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI194239674, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI13236495, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789651, Length=308, Percent_Identity=53.5714285714286, Blast_Score=314, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI71988145, Length=338, Percent_Identity=25.7396449704142, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=367, Percent_Identity=25.0681198910082, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=365, Percent_Identity=24.1095890410959, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=365, Percent_Identity=23.2876712328767, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35695; Mature: 35564

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSRPSLPEPQRPEHFRALRAVKDETGVRPEFQTLTLADLPEGEVLVRVTHSSLNYKDG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCC
LAVAGRPGVLKAYPMTPGIDLAGTVVEDQTGTYRPGDAVLLTGWGIGERQDGGYAEYARV
EEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHE
KAAWLVPLPEGTDAQWAMSVGTAGFTAMLAVMALEEHGVTPGSGEVLVTGAAGGVGSTAV
EEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
ALLAAAGHSVTASTGRREEEDYLRSLGAANIIGREELPALKRPLEKERWAGVVDSVGGDT
HHHHHCCCCEECCCCCCCHHHHHHHCCCCCCCCCHHCHHHHCCHHHHHHHHHHHCCCCHH
LAGALASTRTHGAVAACGLAGGSGLNTTVFPFILRGVNLLGIDSVTCPTERRRAAWARLA
HHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHH
RDLPAAKLAGVTQLRPLSDVPALAQEILAGRVRGRTVIDVTR
HHCCHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
AQSRPSLPEPQRPEHFRALRAVKDETGVRPEFQTLTLADLPEGEVLVRVTHSSLNYKDG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCC
LAVAGRPGVLKAYPMTPGIDLAGTVVEDQTGTYRPGDAVLLTGWGIGERQDGGYAEYARV
EEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHE
KAAWLVPLPEGTDAQWAMSVGTAGFTAMLAVMALEEHGVTPGSGEVLVTGAAGGVGSTAV
EEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
ALLAAAGHSVTASTGRREEEDYLRSLGAANIIGREELPALKRPLEKERWAGVVDSVGGDT
HHHHHCCCCEECCCCCCCHHHHHHHCCCCCCCCCHHCHHHHCCHHHHHHHHHHHCCCCHH
LAGALASTRTHGAVAACGLAGGSGLNTTVFPFILRGVNLLGIDSVTCPTERRRAAWARLA
HHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHH
RDLPAAKLAGVTQLRPLSDVPALAQEILAGRVRGRTVIDVTR
HHCCHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]