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The map label for this gene is yusP [H]

Identifier: 94985249

GI number: 94985249

Start: 1219060

End: 1221168

Strand: Reverse

Name: yusP [H]

Synonym: Dgeo_1147

Alternate gene names: 94985249

Gene position: 1221168-1219060 (Counterclockwise)

Preceding gene: 94985250

Following gene: 94985245

Centisome position: 49.5

GC content: 67.95

Gene sequence:

>2109_bases
ATGACCGTACCCCACCCACCCGGCGCGCCCCCCCAGCGCATCAACTACGCGCAGACGCTGAGCCTCGCCACCAAGCGGGA
AATCCTCTTCGGTGTGCTGCTGGGCCTCTTTCTGAGCGCGCTTGACCAAACCATCGTGGCGACCGCCATGCCGCGCATCG
CTGCCGACCTCAACGGCCTGAACCTGTACGCTTGGGTCACGACGGCGTACCTGCTGACCAATACCGCCCTGGTGCCGATC
TATGGCAAGCTCTCGGACCTGTACGGCCGCAAGCCCGTGCTGATGGTGGGCATCCTGATCTTTCTGCTTGGCTCGGCGCT
GTGCGGTCTGTCGGGCGAAGCCTTTCTTGGGAACCTGTTCGGCGGCGGGATGATGCAGCTCGTCGTGTTCCGCGGTCTCC
AAGGCATCGGTGCGGCGGCGCTCGGCTCGGTCGCCTTTGCCATCGTCGCGGACCTGTTCGAGCCGGCAGAGCGGCCCCGC
TACCAGGGCCTCTTCGGCGCCGTGTTCGGTCTCTCAAGCGTGATCGGCCCGCTGCTGGGCGGCTTCCTCACCGACCAGAT
TTCCTGGCGCTGGGTGTTCTACGTGAACCTGCCGCTGGGTCTGATCGCGCTCTCTTTTATCGCCAGCAAGATGCCCCGGC
TGGCAAGCGGTCTCCAGGCGAAGGTGGACTGGCTGGGTGCTTTCCTGATTATCTTGTTCGCGGTGCCGCTGCTGCTTGCC
CTGACCTGGGGTGCGGACAATACCTATGCCTGGACCAGTGCCACCATCCTGGGCCTCTTCGGCCTGAGTGCCGCCGCCCT
GGTGGCGTTTCTGTTTGTAGAGAGCCGCCACCCCAGCCCGATCCTGCCCCTCACGCTGTTTCGCAACCCCACCTTCGGCT
GGGGCGCGGTGGCCCGGTTCCTGATTGGGGCGGGCTTTTTGGGTGCGGTCCTGTTCCTGAGCCTGTACCTCGTGCAGGTC
AAGGGCGTCAGCGCGACGCGGGCGGGGACCGCCACCATTCCGCTCACGGTGGGCCTGATCATCGGCTCGGTCGGCTCCGG
GCAGATCGCCAGCCGCATCGGGCGCTACAAGCCGCTGATTCTGATTGGCCTGGTCGTGGCGGCCCTGGGCTTTTTCAGCC
TCAGCACCCTCACCGCCGATACTCCCTACTCCGGCGTGATTCTGCGGATGGTTCTGCTGGGCTTGGGCCTCGGCCCCGCA
CTGCCGCTCTACACCACCGCCCTGCAACTCGCCGTCAAGCCCTGGGAAATCGGCGTGGCGACCAGCGCCGGACAGTTCTT
CCAGCAGATGGGAAGCACCATCGGCACCGCGATTTTCGGCGCGATGCTCACGGCGGGCTTGACCACCAACCTCGCCACCC
AGTTTGCCGCCCAGGCCGCCGCGCAGCAGGGTACCGTCGCCACCACCCTCAAGACCATCAGCGAGCGCATCCGCAGCGGC
GCTGCCGGGGGCAGCCAGGACCGCAACGCCGCGCCGCAATCGCCGGAGCAGATCCGCGCCACCTTCGCGACCCTGCGGCA
GAACGTCACCCGGGCCATCGAGCGCGGTGACCCAGCCGCCATCGCGGCCATCCAGAAAGACCCGACCCTGCCCGCCGAGG
CAAAGCAGCGCCTGGCAACTGTGCCTGCCGGGGGTGTGGCAGCAGGCGTGACTGCCGGGTTCAACCAGGTGTACGCGGCG
ATCGCCGGAGCTGTGAACAGCGGCAACCCCGCGCAGGTCGCGGCCGTCGCCGCCAATCCGCAGCTGCCCGCGCCCCTGCG
CCAGCGCCTCGCGCAGCTTCCGCCGCAGGCCCTCCAGAATCCGCAGGCCCGCACTCAGATTCTTGCGGGGATCAAGCAGG
GCCTGGACGCCGCGGCCGCCGCTGCCGCCCAGCAGGCCCAGCAGCAGGCGCTGACGGCAGCGCTGCAGGGTGTGAATGAC
GGAGAGCAGATCGCCCTTGCCAGTGCCCGCGCAACCAAGGTGGCCTTTGCCGAGACCATCGCCAGCATCTACCGCTCCTC
CATCCTGGTGGCGCTGCTTGCCTTTCTCGCCACGCTGCTGATGCCCAACCTCCGCATGCCCACCCGCCAGCAGGGCGAGC
GGCTGGCCCCGGTTCACGTGGAGGCGTAG

Upstream 100 bases:

>100_bases
ATGTCGCGGCCTTTAGCAGCCTGCGGCCCGAGACCATTCGTGCAGCCACCACCTCGATTCGTGCCTTGCTGAACGAACTC
GTTCCTTTCCAGGAGTCCCC

Downstream 100 bases:

>100_bases
GCCGGAACGTCAAGGGGCGGGCGTGGCCATATCCACGCCCGCCCTTCTCAGCGCAGGTGTTTCTGTTCCCAGATCAGATC
GCGCAGCACCCAGCCGCTGC

Product: EmrB/QacA family drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MTVPHPPGAPPQRINYAQTLSLATKREILFGVLLGLFLSALDQTIVATAMPRIAADLNGLNLYAWVTTAYLLTNTALVPI
YGKLSDLYGRKPVLMVGILIFLLGSALCGLSGEAFLGNLFGGGMMQLVVFRGLQGIGAAALGSVAFAIVADLFEPAERPR
YQGLFGAVFGLSSVIGPLLGGFLTDQISWRWVFYVNLPLGLIALSFIASKMPRLASGLQAKVDWLGAFLIILFAVPLLLA
LTWGADNTYAWTSATILGLFGLSAAALVAFLFVESRHPSPILPLTLFRNPTFGWGAVARFLIGAGFLGAVLFLSLYLVQV
KGVSATRAGTATIPLTVGLIIGSVGSGQIASRIGRYKPLILIGLVVAALGFFSLSTLTADTPYSGVILRMVLLGLGLGPA
LPLYTTALQLAVKPWEIGVATSAGQFFQQMGSTIGTAIFGAMLTAGLTTNLATQFAAQAAAQQGTVATTLKTISERIRSG
AAGGSQDRNAAPQSPEQIRATFATLRQNVTRAIERGDPAAIAAIQKDPTLPAEAKQRLATVPAGGVAAGVTAGFNQVYAA
IAGAVNSGNPAQVAAVAANPQLPAPLRQRLAQLPPQALQNPQARTQILAGIKQGLDAAAAAAAQQAQQQALTAALQGVND
GEQIALASARATKVAFAETIASIYRSSILVALLAFLATLLMPNLRMPTRQQGERLAPVHVEA

Sequences:

>Translated_702_residues
MTVPHPPGAPPQRINYAQTLSLATKREILFGVLLGLFLSALDQTIVATAMPRIAADLNGLNLYAWVTTAYLLTNTALVPI
YGKLSDLYGRKPVLMVGILIFLLGSALCGLSGEAFLGNLFGGGMMQLVVFRGLQGIGAAALGSVAFAIVADLFEPAERPR
YQGLFGAVFGLSSVIGPLLGGFLTDQISWRWVFYVNLPLGLIALSFIASKMPRLASGLQAKVDWLGAFLIILFAVPLLLA
LTWGADNTYAWTSATILGLFGLSAAALVAFLFVESRHPSPILPLTLFRNPTFGWGAVARFLIGAGFLGAVLFLSLYLVQV
KGVSATRAGTATIPLTVGLIIGSVGSGQIASRIGRYKPLILIGLVVAALGFFSLSTLTADTPYSGVILRMVLLGLGLGPA
LPLYTTALQLAVKPWEIGVATSAGQFFQQMGSTIGTAIFGAMLTAGLTTNLATQFAAQAAAQQGTVATTLKTISERIRSG
AAGGSQDRNAAPQSPEQIRATFATLRQNVTRAIERGDPAAIAAIQKDPTLPAEAKQRLATVPAGGVAAGVTAGFNQVYAA
IAGAVNSGNPAQVAAVAANPQLPAPLRQRLAQLPPQALQNPQARTQILAGIKQGLDAAAAAAAQQAQQQALTAALQGVND
GEQIALASARATKVAFAETIASIYRSSILVALLAFLATLLMPNLRMPTRQQGERLAPVHVEA
>Mature_701_residues
TVPHPPGAPPQRINYAQTLSLATKREILFGVLLGLFLSALDQTIVATAMPRIAADLNGLNLYAWVTTAYLLTNTALVPIY
GKLSDLYGRKPVLMVGILIFLLGSALCGLSGEAFLGNLFGGGMMQLVVFRGLQGIGAAALGSVAFAIVADLFEPAERPRY
QGLFGAVFGLSSVIGPLLGGFLTDQISWRWVFYVNLPLGLIALSFIASKMPRLASGLQAKVDWLGAFLIILFAVPLLLAL
TWGADNTYAWTSATILGLFGLSAAALVAFLFVESRHPSPILPLTLFRNPTFGWGAVARFLIGAGFLGAVLFLSLYLVQVK
GVSATRAGTATIPLTVGLIIGSVGSGQIASRIGRYKPLILIGLVVAALGFFSLSTLTADTPYSGVILRMVLLGLGLGPAL
PLYTTALQLAVKPWEIGVATSAGQFFQQMGSTIGTAIFGAMLTAGLTTNLATQFAAQAAAQQGTVATTLKTISERIRSGA
AGGSQDRNAAPQSPEQIRATFATLRQNVTRAIERGDPAAIAAIQKDPTLPAEAKQRLATVPAGGVAAGVTAGFNQVYAAI
AGAVNSGNPAQVAAVAANPQLPAPLRQRLAQLPPQALQNPQARTQILAGIKQGLDAAAAAAAQQAQQQALTAALQGVNDG
EQIALASARATKVAFAETIASIYRSSILVALLAFLATLLMPNLRMPTRQQGERLAPVHVEA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=349, Percent_Identity=31.2320916905444, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1789042, Length=415, Percent_Identity=25.3012048192771, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788710, Length=408, Percent_Identity=25.4901960784314, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081983, Length=390, Percent_Identity=26.9230769230769, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1788392, Length=365, Percent_Identity=29.8630136986301, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790146, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994889, Length=114, Percent_Identity=35.9649122807018, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=463, Percent_Identity=27.2138228941685, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323735, Length=337, Percent_Identity=28.486646884273, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321663, Length=385, Percent_Identity=25.1948051948052, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319783, Length=372, Percent_Identity=26.6129032258064, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319770, Length=391, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325455, Length=405, Percent_Identity=22.4691358024691, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323520, Length=261, Percent_Identity=24.1379310344828, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 73018; Mature: 72887

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPHPPGAPPQRINYAQTLSLATKREILFGVLLGLFLSALDQTIVATAMPRIAADLNGL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NLYAWVTTAYLLTNTALVPIYGKLSDLYGRKPVLMVGILIFLLGSALCGLSGEAFLGNLF
CHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GGGMMQLVVFRGLQGIGAAALGSVAFAIVADLFEPAERPRYQGLFGAVFGLSSVIGPLLG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GFLTDQISWRWVFYVNLPLGLIALSFIASKMPRLASGLQAKVDWLGAFLIILFAVPLLLA
HHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTWGADNTYAWTSATILGLFGLSAAALVAFLFVESRHPSPILPLTLFRNPTFGWGAVARF
HHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHH
LIGAGFLGAVLFLSLYLVQVKGVSATRAGTATIPLTVGLIIGSVGSGQIASRIGRYKPLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHH
LIGLVVAALGFFSLSTLTADTPYSGVILRMVLLGLGLGPALPLYTTALQLAVKPWEIGVA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHCCCC
TSAGQFFQQMGSTIGTAIFGAMLTAGLTTNLATQFAAQAAAQQGTVATTLKTISERIRSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AAGGSQDRNAAPQSPEQIRATFATLRQNVTRAIERGDPAAIAAIQKDPTLPAEAKQRLAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHC
VPAGGVAAGVTAGFNQVYAAIAGAVNSGNPAQVAAVAANPQLPAPLRQRLAQLPPQALQN
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHCC
PQARTQILAGIKQGLDAAAAAAAQQAQQQALTAALQGVNDGEQIALASARATKVAFAETI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
ASIYRSSILVALLAFLATLLMPNLRMPTRQQGERLAPVHVEA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEECC
>Mature Secondary Structure 
TVPHPPGAPPQRINYAQTLSLATKREILFGVLLGLFLSALDQTIVATAMPRIAADLNGL
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NLYAWVTTAYLLTNTALVPIYGKLSDLYGRKPVLMVGILIFLLGSALCGLSGEAFLGNLF
CHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GGGMMQLVVFRGLQGIGAAALGSVAFAIVADLFEPAERPRYQGLFGAVFGLSSVIGPLLG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GFLTDQISWRWVFYVNLPLGLIALSFIASKMPRLASGLQAKVDWLGAFLIILFAVPLLLA
HHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTWGADNTYAWTSATILGLFGLSAAALVAFLFVESRHPSPILPLTLFRNPTFGWGAVARF
HHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHH
LIGAGFLGAVLFLSLYLVQVKGVSATRAGTATIPLTVGLIIGSVGSGQIASRIGRYKPLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHH
LIGLVVAALGFFSLSTLTADTPYSGVILRMVLLGLGLGPALPLYTTALQLAVKPWEIGVA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHCCCC
TSAGQFFQQMGSTIGTAIFGAMLTAGLTTNLATQFAAQAAAQQGTVATTLKTISERIRSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AAGGSQDRNAAPQSPEQIRATFATLRQNVTRAIERGDPAAIAAIQKDPTLPAEAKQRLAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHC
VPAGGVAAGVTAGFNQVYAAIAGAVNSGNPAQVAAVAANPQLPAPLRQRLAQLPPQALQN
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHCC
PQARTQILAGIKQGLDAAAAAAAQQAQQQALTAALQGVNDGEQIALASARATKVAFAETI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
ASIYRSSILVALLAFLATLLMPNLRMPTRQQGERLAPVHVEA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]