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The map label for this gene is ispH [H]

Identifier: 94985115

GI number: 94985115

Start: 1081831

End: 1082826

Strand: Reverse

Name: ispH [H]

Synonym: Dgeo_1010

Alternate gene names: 94985115

Gene position: 1082826-1081831 (Counterclockwise)

Preceding gene: 94985116

Following gene: 94985111

Centisome position: 43.89

GC content: 62.65

Gene sequence:

>996_bases
ATGGTTGAACGGATTCATCTTGCCAAGCCGCGCGGCTTCTGCGCGGGCGTGGTGATGGCCATCCAGGCGGTCGAAAAAGC
CGCTCGTACCGAAGACCGTCCCGTGACGGTCTATCATTCCATTGTCCACAACCACACCGTTGTCGAGCGGTTGGAACAGG
AACATGGCGTGCAGTTTGTGGAGAGCCTGGACGATCTAACAGCCCTCCCGAACGGCAGCGAGACGGTGATCTTTAGCGCT
CACGGCATCAGCCCAGCGGTGCGCGAGCGGGCGCGGGCCTTGGGCGTGAGCACCATCGACGCAACCTGTCCGCTGGTGAC
CAAGGTCCACACCGAGGCGAAAAAGTACGCTCGCGAGGGCTATACCATCCTGCTGATCGGGGACAGCGCGCGGCACCAGG
AAGTCATCGGCACACGCGGCGAGGCCCCCGAACAGACCATCGTGGTGGGCGTACTGGGCAAAACGGGAGAAGGACTACAC
GACCCCCATACCGTCGAAGTACCTGATCCCGAGCGGGTGGTGGTCCTCACGCAGACGACCCTCAGTGTGGACGATACCCG
CCGCACCATCGACATCCTGAAAACCCGCTTTCCGAAGCTGGTGATTCCACCCAGCGAAGATCTCTGCTACGCCACCAAGA
ACCGCCAGGAGGCCGTCAAGGCGATCGCTCCACAGGTCGACGCTTTTCTGGTGCTGACCAGCACTCATTCCAGCAACGGG
ATGCGCCTGCTGGAACTCGCCCGCGACCTGTGCGGCCGGGCCGAGCGCCTGGAAACCGCTGACGACCTCGCGCACCTCGA
CCTGACCGGTGTGTACTCGCTGGGCATCACCAGTGCAGCCAGCACACCCGATGACCTCGTCCAGAAAGTGGTCGCCCACT
TCCGCCGGCTCAATCCGAACCTTGAAGTCATCGAGGAAGGCGAGTGGGAAAACATCGAGTTCCGCGAACCTAAAAAGATC
GGGCCGGGGCAGGCCCTCCCCCGGACAACGCAGTAG

Upstream 100 bases:

>100_bases
GCGGAACGTGGAGGAGGGACCGCAGCACTGACTGTACGGGACTTCTCGCACCCTCCGGCCGGGCCTTCCCACCTACACTA
GGGAGGTGACGGGAGCCACC

Downstream 100 bases:

>100_bases
CTTTTCTGGCCCCCTAGCCTTCGCGGATATACCCCGTTCGCAAAAACTCCTGTACCAGCGGCTCCAGATCATGGAGGGCG
AGGTCACTGCGCATGGCGTA

Product: hydroxymethylbutenyl pyrophosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MVERIHLAKPRGFCAGVVMAIQAVEKAARTEDRPVTVYHSIVHNHTVVERLEQEHGVQFVESLDDLTALPNGSETVIFSA
HGISPAVRERARALGVSTIDATCPLVTKVHTEAKKYAREGYTILLIGDSARHQEVIGTRGEAPEQTIVVGVLGKTGEGLH
DPHTVEVPDPERVVVLTQTTLSVDDTRRTIDILKTRFPKLVIPPSEDLCYATKNRQEAVKAIAPQVDAFLVLTSTHSSNG
MRLLELARDLCGRAERLETADDLAHLDLTGVYSLGITSAASTPDDLVQKVVAHFRRLNPNLEVIEEGEWENIEFREPKKI
GPGQALPRTTQ

Sequences:

>Translated_331_residues
MVERIHLAKPRGFCAGVVMAIQAVEKAARTEDRPVTVYHSIVHNHTVVERLEQEHGVQFVESLDDLTALPNGSETVIFSA
HGISPAVRERARALGVSTIDATCPLVTKVHTEAKKYAREGYTILLIGDSARHQEVIGTRGEAPEQTIVVGVLGKTGEGLH
DPHTVEVPDPERVVVLTQTTLSVDDTRRTIDILKTRFPKLVIPPSEDLCYATKNRQEAVKAIAPQVDAFLVLTSTHSSNG
MRLLELARDLCGRAERLETADDLAHLDLTGVYSLGITSAASTPDDLVQKVVAHFRRLNPNLEVIEEGEWENIEFREPKKI
GPGQALPRTTQ
>Mature_331_residues
MVERIHLAKPRGFCAGVVMAIQAVEKAARTEDRPVTVYHSIVHNHTVVERLEQEHGVQFVESLDDLTALPNGSETVIFSA
HGISPAVRERARALGVSTIDATCPLVTKVHTEAKKYAREGYTILLIGDSARHQEVIGTRGEAPEQTIVVGVLGKTGEGLH
DPHTVEVPDPERVVVLTQTTLSVDDTRRTIDILKTRFPKLVIPPSEDLCYATKNRQEAVKAIAPQVDAFLVLTSTHSSNG
MRLLELARDLCGRAERLETADDLAHLDLTGVYSLGITSAASTPDDLVQKVVAHFRRLNPNLEVIEEGEWENIEFREPKKI
GPGQALPRTTQ

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=319, Percent_Identity=44.5141065830721, Blast_Score=234, Evalue=8e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 36339; Mature: 36339

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERIHLAKPRGFCAGVVMAIQAVEKAARTEDRPVTVYHSIVHNHTVVERLEQEHGVQFV
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
ESLDDLTALPNGSETVIFSAHGISPAVRERARALGVSTIDATCPLVTKVHTEAKKYAREG
HHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
YTILLIGDSARHQEVIGTRGEAPEQTIVVGVLGKTGEGLHDPHTVEVPDPERVVVLTQTT
CEEEEECCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCEEEEEEEEE
LSVDDTRRTIDILKTRFPKLVIPPSEDLCYATKNRQEAVKAIAPQVDAFLVLTSTHSSNG
ECCCHHHHHHHHHHHCCCEEEECCCCCCEEECCCHHHHHHHHCCCCCEEEEEEECCCCCC
MRLLELARDLCGRAERLETADDLAHLDLTGVYSLGITSAASTPDDLVQKVVAHFRRLNPN
CHHHHHHHHHHCHHHHHCHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
LEVIEEGEWENIEFREPKKIGPGQALPRTTQ
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVERIHLAKPRGFCAGVVMAIQAVEKAARTEDRPVTVYHSIVHNHTVVERLEQEHGVQFV
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
ESLDDLTALPNGSETVIFSAHGISPAVRERARALGVSTIDATCPLVTKVHTEAKKYAREG
HHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
YTILLIGDSARHQEVIGTRGEAPEQTIVVGVLGKTGEGLHDPHTVEVPDPERVVVLTQTT
CEEEEECCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCEEEEEEEEE
LSVDDTRRTIDILKTRFPKLVIPPSEDLCYATKNRQEAVKAIAPQVDAFLVLTSTHSSNG
ECCCHHHHHHHHHHHCCCEEEECCCCCCEEECCCHHHHHHHHCCCCCEEEEEEECCCCCC
MRLLELARDLCGRAERLETADDLAHLDLTGVYSLGITSAASTPDDLVQKVVAHFRRLNPN
CHHHHHHHHHHCHHHHHCHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
LEVIEEGEWENIEFREPKKIGPGQALPRTTQ
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]