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The map label for this gene is coaE [H]

Identifier: 94984935

GI number: 94984935

Start: 888596

End: 889255

Strand: Reverse

Name: coaE [H]

Synonym: Dgeo_0828

Alternate gene names: 94984935

Gene position: 889255-888596 (Counterclockwise)

Preceding gene: 94984938

Following gene: 94984931

Centisome position: 36.04

GC content: 72.73

Gene sequence:

>660_bases
ATGCCGCGTCCTCCTGCATCCCACCCTCGCCGCCTGGGCCTGACGGGCAGCATCGGCGCAGGCAAAAGTACCGTTGCCCG
CCTGTTGCGCGCGCGCGGCCTGACTGTCCTCGACGCCGACGAGGTGGCCCGCGAGGTCACGCGCGACCCGGCGGTGCTGG
CCGAGATTGAGGCGGCCTTTCCCGGCGTGGTGCGGGGAGGCGTGCTCGACCGCGCGGCTCTGGCCGCCGCCGCCTTCGCG
GACCCCGCGCGGCTCGCGCTGCTGAACGCCATTACCCATCCACGCGTGCGGCAGAAGATGCTGGCACTGGAGCAGGCCGC
CGCTGCACGCGGCGAAAGCTGGGTCGTGCAGGACGTGCCCCTGCTGTTCGAGGGCGGGCTGGAAGCGGGGATGGACGCCG
TGCTGGTGGTGGACGCCCCGCTGGACCTGCGCCTGGCCCGCGTGGCTGCCCGCAGTGGCCTCACGGCAGAGGAGGTGCTG
GCGCGCGACGCCCGGCAGATGTCCGCAGAGGAGAAGCGGAAGCGGGCAACGGTCGTGCTGGACAACAGCGGCGACCTGGC
GAACCTGGAGCGACAGGTGGCTGCGGCGCTCGACACACTGGGCGTTTGGCCGCTCACCGCAAGCCGCAGCCAGCCAGACG
AAAGCCCCAGCCGGAGCTGA

Upstream 100 bases:

>100_bases
GTGTTGACTGGCTTCTGATGCGTCCCCCCGGCGCGCCCCTGCCGTCCGCCTACCTGCCTACACTCTACGCCTACACTCTA
CACTGCCTACACTGATCGTC

Downstream 100 bases:

>100_bases
GGCTCTTTTTCCCAGCGGTGCCGCTGCCGCCGCTTACGCTTCTGCCGCCACGGTTTGGCCGCTGGCAGCGGACGACGGTC
CACTCTGCAGCGCCGCAGCC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPRPPASHPRRLGLTGSIGAGKSTVARLLRARGLTVLDADEVAREVTRDPAVLAEIEAAFPGVVRGGVLDRAALAAAAFA
DPARLALLNAITHPRVRQKMLALEQAAAARGESWVVQDVPLLFEGGLEAGMDAVLVVDAPLDLRLARVAARSGLTAEEVL
ARDARQMSAEEKRKRATVVLDNSGDLANLERQVAAALDTLGVWPLTASRSQPDESPSRS

Sequences:

>Translated_219_residues
MPRPPASHPRRLGLTGSIGAGKSTVARLLRARGLTVLDADEVAREVTRDPAVLAEIEAAFPGVVRGGVLDRAALAAAAFA
DPARLALLNAITHPRVRQKMLALEQAAAARGESWVVQDVPLLFEGGLEAGMDAVLVVDAPLDLRLARVAARSGLTAEEVL
ARDARQMSAEEKRKRATVVLDNSGDLANLERQVAAALDTLGVWPLTASRSQPDESPSRS
>Mature_218_residues
PRPPASHPRRLGLTGSIGAGKSTVARLLRARGLTVLDADEVAREVTRDPAVLAEIEAAFPGVVRGGVLDRAALAAAAFAD
PARLALLNAITHPRVRQKMLALEQAAAARGESWVVQDVPLLFEGGLEAGMDAVLVVDAPLDLRLARVAARSGLTAEEVLA
RDARQMSAEEKRKRATVVLDNSGDLANLERQVAAALDTLGVWPLTASRSQPDESPSRS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=186, Percent_Identity=37.0967741935484, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI191252795, Length=186, Percent_Identity=37.0967741935484, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI110227607, Length=218, Percent_Identity=27.9816513761468, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227605, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI110227603, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI110227601, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI205277394, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=37.5, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554944, Length=191, Percent_Identity=32.9842931937173, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=34.5177664974619, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644728, Length=184, Percent_Identity=32.0652173913043, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658602, Length=209, Percent_Identity=30.622009569378, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23113; Mature: 22982

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPPASHPRRLGLTGSIGAGKSTVARLLRARGLTVLDADEVAREVTRDPAVLAEIEAAF
CCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHCCCHHHHHHHHHC
PGVVRGGVLDRAALAAAAFADPARLALLNAITHPRVRQKMLALEQAAAARGESWVVQDVP
CHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCC
LLFEGGLEAGMDAVLVVDAPLDLRLARVAARSGLTAEEVLARDARQMSAEEKRKRATVVL
HHHHCCHHHCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
DNSGDLANLERQVAAALDTLGVWPLTASRSQPDESPSRS
ECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRPPASHPRRLGLTGSIGAGKSTVARLLRARGLTVLDADEVAREVTRDPAVLAEIEAAF
CCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHCCCHHHHHHHHHC
PGVVRGGVLDRAALAAAAFADPARLALLNAITHPRVRQKMLALEQAAAARGESWVVQDVP
CHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCC
LLFEGGLEAGMDAVLVVDAPLDLRLARVAARSGLTAEEVLARDARQMSAEEKRKRATVVL
HHHHCCHHHCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
DNSGDLANLERQVAAALDTLGVWPLTASRSQPDESPSRS
ECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]