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The map label for this gene is suhB [H]

Identifier: 94984902

GI number: 94984902

Start: 851413

End: 852621

Strand: Reverse

Name: suhB [H]

Synonym: Dgeo_0795

Alternate gene names: 94984902

Gene position: 852621-851413 (Counterclockwise)

Preceding gene: 94984906

Following gene: 94984901

Centisome position: 34.56

GC content: 69.48

Gene sequence:

>1209_bases
GTGGGGTCGGGGGCGCGGCGTACGGCGAGACGTCCCCTAACAGGGATCGTCATTCACGTTGTTGGCGTACGCCGCCTTCA
TGAGGAGAAGTGTAACGGGGACACGCTGAGCGGGTCAATGTGGGAGGCTAGGCAGGGAGAGGGCAGGCGGCTCTGGCACG
GTCCCGCTCTCCCGTATCTTCCTTCCATGACCCTGAGCCACGAACGGACGGTCGCCACCCGGCTCGCGCTGGAGGCGGGC
GAGTTGCTGAGAACGCACCTGGAACGCGGATTGACCGTCGAACACAAGACCTCGGCCGATGATCCGGTGACCGCCGCCGA
CCGCGAGGCCTCCGAGTTGATCCTGGCTGGGCTGAGAGCCGCCTTTGCGGAGGATGGACTGCTCAGCGAGGAGGCCGCCG
ACACCTCCGCGCGGCTGGGCCAGGAGCGCGTGTGGATTGTGGACCCCATCGACGGAACGAAGGAGTTCACCTCAGGCAGC
CCCGACTACGCCGTGTCTATCGGGCTGGCGGTAGGAGGCGAGCCGGTGCTGGGCGTCGTCTATGCCCCCGCAACGGACGA
GCTGTTCGTGGGCGTGGTCGGCGAGGGGGTCACGAAGAACGGCACACCTGCGGGCTTCAGCCACCGCACGGAATACGTGG
TCAGTGTGTCGGACACGGAGTTTAAGCGGGAACTGCACCGGCACGACCTCCCCGGCATGGTCCCCAGCGGGTCCATCGCC
CTCAAGCTCGCGCGGATCGCGGCGGGCGAGGCCGATGTGACCTTTACCATGTCCCCGCGCTCGGAGTGGGACATCGCGGC
AGGTCACGCACTTGTGCGGGCGGCCGGGGGCGAGGTGCGGCGGCGAGACGGGCGAGCGATCCGATACAACGTGGCGCGGC
CCCACCTCGAGCAGGGCATCATCGGGGGACGGCCGGAGGCGATGGACTGGCTGGAAGGTGAGCTGCGGGCGCGGAACCTC
CCCACGGCGCACCTGAGCCTGACGAGTGCCGATCCCGCCTGGGCCGTCCTCCCCCCCGAGGATCAAGCCGCCCTTGACGG
GCATCCCACCGTCTTCCTGCGCCACGCGGGGGGCCGGGTGCTCGCGCTGCTGGTGGTCGGGCCGGACGGCAACGTGGAGC
GAGCTTCGGGGGACGCCTTTCACCTCGAACGCCTGACGCGCGACGTGACGCGGGCGCTGGGCCGTGAGCCTGCGAAGGTC
GGGGGCTAG

Upstream 100 bases:

>100_bases
CATGTTGGGGCAGCTCGCGGGTCAGGGTGCGTTTCAGTTGCGTGAGGGGTTCGGTGGTCACAGTCAGGTCTCCTTGCTAG
GCAAAGCCCCCGACTCCGGT

Downstream 100 bases:

>100_bases
ACTGGCACGCATGGCGGCAGAAGGCACAGGCATTTCTTGGGGGCGCGTCACCCTCAAGCCCGTCCCGGAGTTCACGCCCG
CCGAGTGGCACACCCTCTAC

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MGSGARRTARRPLTGIVIHVVGVRRLHEEKCNGDTLSGSMWEARQGEGRRLWHGPALPYLPSMTLSHERTVATRLALEAG
ELLRTHLERGLTVEHKTSADDPVTAADREASELILAGLRAAFAEDGLLSEEAADTSARLGQERVWIVDPIDGTKEFTSGS
PDYAVSIGLAVGGEPVLGVVYAPATDELFVGVVGEGVTKNGTPAGFSHRTEYVVSVSDTEFKRELHRHDLPGMVPSGSIA
LKLARIAAGEADVTFTMSPRSEWDIAAGHALVRAAGGEVRRRDGRAIRYNVARPHLEQGIIGGRPEAMDWLEGELRARNL
PTAHLSLTSADPAWAVLPPEDQAALDGHPTVFLRHAGGRVLALLVVGPDGNVERASGDAFHLERLTRDVTRALGREPAKV
GG

Sequences:

>Translated_402_residues
MGSGARRTARRPLTGIVIHVVGVRRLHEEKCNGDTLSGSMWEARQGEGRRLWHGPALPYLPSMTLSHERTVATRLALEAG
ELLRTHLERGLTVEHKTSADDPVTAADREASELILAGLRAAFAEDGLLSEEAADTSARLGQERVWIVDPIDGTKEFTSGS
PDYAVSIGLAVGGEPVLGVVYAPATDELFVGVVGEGVTKNGTPAGFSHRTEYVVSVSDTEFKRELHRHDLPGMVPSGSIA
LKLARIAAGEADVTFTMSPRSEWDIAAGHALVRAAGGEVRRRDGRAIRYNVARPHLEQGIIGGRPEAMDWLEGELRARNL
PTAHLSLTSADPAWAVLPPEDQAALDGHPTVFLRHAGGRVLALLVVGPDGNVERASGDAFHLERLTRDVTRALGREPAKV
GG
>Mature_401_residues
GSGARRTARRPLTGIVIHVVGVRRLHEEKCNGDTLSGSMWEARQGEGRRLWHGPALPYLPSMTLSHERTVATRLALEAGE
LLRTHLERGLTVEHKTSADDPVTAADREASELILAGLRAAFAEDGLLSEEAADTSARLGQERVWIVDPIDGTKEFTSGSP
DYAVSIGLAVGGEPVLGVVYAPATDELFVGVVGEGVTKNGTPAGFSHRTEYVVSVSDTEFKRELHRHDLPGMVPSGSIAL
KLARIAAGEADVTFTMSPRSEWDIAAGHALVRAAGGEVRRRDGRAIRYNVARPHLEQGIIGGRPEAMDWLEGELRARNLP
TAHLSLTSADPAWAVLPPEDQAALDGHPTVFLRHAGGRVLALLVVGPDGNVERASGDAFHLERLTRDVTRALGREPAKVG
G

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=226, Percent_Identity=35.3982300884956, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI221625487, Length=223, Percent_Identity=28.6995515695067, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI5031789, Length=223, Percent_Identity=28.6995515695067, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI221625507, Length=140, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1788882, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790659, Length=205, Percent_Identity=31.219512195122, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193202572, Length=232, Percent_Identity=29.7413793103448, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193202570, Length=231, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71995905, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320493, Length=234, Percent_Identity=26.4957264957265, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24664922, Length=262, Percent_Identity=33.206106870229, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24664926, Length=242, Percent_Identity=31.404958677686, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21357329, Length=226, Percent_Identity=30.9734513274336, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357957, Length=245, Percent_Identity=30.2040816326531, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24664918, Length=242, Percent_Identity=30.1652892561983, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357303, Length=232, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641722, Length=223, Percent_Identity=24.2152466367713, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 43052; Mature: 42921

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGARRTARRPLTGIVIHVVGVRRLHEEKCNGDTLSGSMWEARQGEGRRLWHGPALPYL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
PSMTLSHERTVATRLALEAGELLRTHLERGLTVEHKTSADDPVTAADREASELILAGLRA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
AFAEDGLLSEEAADTSARLGQERVWIVDPIDGTKEFTSGSPDYAVSIGLAVGGEPVLGVV
HHHCCCCCCHHHCCHHHHCCCCEEEEECCCCCCHHHCCCCCCEEEEEEEEECCCCEEEEE
YAPATDELFVGVVGEGVTKNGTPAGFSHRTEYVVSVSDTEFKRELHRHDLPGMVPSGSIA
ECCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCHHE
LKLARIAAGEADVTFTMSPRSEWDIAAGHALVRAAGGEVRRRDGRAIRYNVARPHLEQGI
EEEEEHHCCCCCEEEEECCCCCCCHHHCHHHEECCCCCHHHCCCCEEEEECCCCHHHHCC
IGGRPEAMDWLEGELRARNLPTAHLSLTSADPAWAVLPPEDQAALDGHPTVFLRHAGGRV
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCCEE
LALLVVGPDGNVERASGDAFHLERLTRDVTRALGREPAKVGG
EEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GSGARRTARRPLTGIVIHVVGVRRLHEEKCNGDTLSGSMWEARQGEGRRLWHGPALPYL
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
PSMTLSHERTVATRLALEAGELLRTHLERGLTVEHKTSADDPVTAADREASELILAGLRA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
AFAEDGLLSEEAADTSARLGQERVWIVDPIDGTKEFTSGSPDYAVSIGLAVGGEPVLGVV
HHHCCCCCCHHHCCHHHHCCCCEEEEECCCCCCHHHCCCCCCEEEEEEEEECCCCEEEEE
YAPATDELFVGVVGEGVTKNGTPAGFSHRTEYVVSVSDTEFKRELHRHDLPGMVPSGSIA
ECCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCHHE
LKLARIAAGEADVTFTMSPRSEWDIAAGHALVRAAGGEVRRRDGRAIRYNVARPHLEQGI
EEEEEHHCCCCCEEEEECCCCCCCHHHCHHHEECCCCCHHHCCCCEEEEECCCCHHHHCC
IGGRPEAMDWLEGELRARNLPTAHLSLTSADPAWAVLPPEDQAALDGHPTVFLRHAGGRV
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCCEE
LALLVVGPDGNVERASGDAFHLERLTRDVTRALGREPAKVGG
EEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]