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The map label for this gene is nhaA2 [H]

Identifier: 94984854

GI number: 94984854

Start: 807815

End: 808822

Strand: Reverse

Name: nhaA2 [H]

Synonym: Dgeo_0747

Alternate gene names: 94984854

Gene position: 808822-807815 (Counterclockwise)

Preceding gene: 94984855

Following gene: 94984849

Centisome position: 32.78

GC content: 68.95

Gene sequence:

>1008_bases
ATGAACCGTGTGATCGGTCTGGTGGCGGGAGCACTCCTCGCCGCAAATCTGGGAAGCCAGGCAAGCGCCCAACTGCTCGC
AACGCCTGCCGCAACGGCGGCGCAGCCTCTGCTGGCGGGATTCCGGGTCAGTGGGAGCACCCTAACACGGGGCACCACCA
CACTCACGCTGGACACGGCCGGGGGCCGCGTGGTGGGCGTACTGGTGCAGGCGGACAACCCGCAAGACGTGGCGCGAGCG
CTGGTGGCCGCCTGGGGGGGTCCTGAGCAGAACGTGGCGGCCGTCGCCCAGGCCCTGGGCCGCGACGACCTGCAACGGGA
GGCCCGCGGCGCCCAGGGCCTGCGGGACGACAGCGAGGGCACCCTCCTGCGGGTCAAGCTGAACGGGACGGGCGGCGCCC
AGCGCTGGACCGCCTACACCGCCCTCCTGATCTTCCCCGACCGCGCCTTTCCCGCGACCGCGAACGTGCAGGGAAGCGCG
CAGGCGCCCAACGTCCTGCGCATCTTCAGCGACTTCCAGTGTCCCTACTGCAAGGAGCTGTGGGACACGGCGCACCCGAA
GTGGGCCGCCCAGCCGAACGTGTACCGGGTGATGCACTACCACTTTCCGTTGAGCTTCCACAAGAATGCAGAACCGGCGG
CCATTGCCAGCGAGTGCGCCGCGGAGCAGGGAAAATTCTGGCCGTATGCCGATCTGCTGTTCCGCCATACCGCCGAGTGG
ACCGGGCTGCCCTCCGCCAGCGCCAAATTCAGCGAGTACGCTCAGGCCGCTGGGCTGAATGTCGCCGCCTTCCAGACCTG
CCTGACCAGCGCCGCGCCAAAAGCCGTTGTCCGGGCGCAGCAGGCCGCGGGCCTCAAGCTGGGCGTGCAGGGCACACCGA
CGGTGTACCTCAACGGCGTCCAACTGCGAAACTACAGCGACGAGAACGAATTGGCCGCTGTGCGTGCAGTTACGGCGGCC
TCGCCGGGCGCGGTGGAGGTGATCGCGGCACGCCTGAAGCGCTTCTAG

Upstream 100 bases:

>100_bases
ACCTGCTGGAGCAAGCAGAACCCGCAGAGCACCTGACACGCTTCCCCACCTAGGCTCTGCCGCAACGCGGCTCACCTCTC
CCCGCCGCTAGACTGCCCGC

Downstream 100 bases:

>100_bases
CCTCTTACAGCCGCAGCAGGGGCCGCCACCACGGGATCGCCAGCAGCACCGCGAGCAGGCTGAGGACCGTCCAGAGGCTC
GCGGTGCGGAACTTGGCCTG

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNRVIGLVAGALLAANLGSQASAQLLATPAATAAQPLLAGFRVSGSTLTRGTTTLTLDTAGGRVVGVLVQADNPQDVARA
LVAAWGGPEQNVAAVAQALGRDDLQREARGAQGLRDDSEGTLLRVKLNGTGGAQRWTAYTALLIFPDRAFPATANVQGSA
QAPNVLRIFSDFQCPYCKELWDTAHPKWAAQPNVYRVMHYHFPLSFHKNAEPAAIASECAAEQGKFWPYADLLFRHTAEW
TGLPSASAKFSEYAQAAGLNVAAFQTCLTSAAPKAVVRAQQAAGLKLGVQGTPTVYLNGVQLRNYSDENELAAVRAVTAA
SPGAVEVIAARLKRF

Sequences:

>Translated_335_residues
MNRVIGLVAGALLAANLGSQASAQLLATPAATAAQPLLAGFRVSGSTLTRGTTTLTLDTAGGRVVGVLVQADNPQDVARA
LVAAWGGPEQNVAAVAQALGRDDLQREARGAQGLRDDSEGTLLRVKLNGTGGAQRWTAYTALLIFPDRAFPATANVQGSA
QAPNVLRIFSDFQCPYCKELWDTAHPKWAAQPNVYRVMHYHFPLSFHKNAEPAAIASECAAEQGKFWPYADLLFRHTAEW
TGLPSASAKFSEYAQAAGLNVAAFQTCLTSAAPKAVVRAQQAAGLKLGVQGTPTVYLNGVQLRNYSDENELAAVRAVTAA
SPGAVEVIAARLKRF
>Mature_335_residues
MNRVIGLVAGALLAANLGSQASAQLLATPAATAAQPLLAGFRVSGSTLTRGTTTLTLDTAGGRVVGVLVQADNPQDVARA
LVAAWGGPEQNVAAVAQALGRDDLQREARGAQGLRDDSEGTLLRVKLNGTGGAQRWTAYTALLIFPDRAFPATANVQGSA
QAPNVLRIFSDFQCPYCKELWDTAHPKWAAQPNVYRVMHYHFPLSFHKNAEPAAIASECAAEQGKFWPYADLLFRHTAEW
TGLPSASAKFSEYAQAAGLNVAAFQTCLTSAAPKAVVRAQQAAGLKLGVQGTPTVYLNGVQLRNYSDENELAAVRAVTAA
SPGAVEVIAARLKRF

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 35324; Mature: 35324

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVIGLVAGALLAANLGSQASAQLLATPAATAAQPLLAGFRVSGSTLTRGTTTLTLDTA
CCHHHHHHHHHHHHHCCCCCCCHHEEECCCHHHHHHHHHHEEECCCEEECCEEEEEEECC
GGRVVGVLVQADNPQDVARALVAAWGGPEQNVAAVAQALGRDDLQREARGAQGLRDDSEG
CCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
TLLRVKLNGTGGAQRWTAYTALLIFPDRAFPATANVQGSAQAPNVLRIFSDFQCPYCKEL
CEEEEEECCCCCCCHHEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHH
WDTAHPKWAAQPNVYRVMHYHFPLSFHKNAEPAAIASECAAEQGKFWPYADLLFRHTAEW
HHCCCCCCCCCCCEEEEEEEEECEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TGLPSASAKFSEYAQAAGLNVAAFQTCLTSAAPKAVVRAQQAAGLKLGVQGTPTVYLNGV
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCEEEEEEE
QLRNYSDENELAAVRAVTAASPGAVEVIAARLKRF
EEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNRVIGLVAGALLAANLGSQASAQLLATPAATAAQPLLAGFRVSGSTLTRGTTTLTLDTA
CCHHHHHHHHHHHHHCCCCCCCHHEEECCCHHHHHHHHHHEEECCCEEECCEEEEEEECC
GGRVVGVLVQADNPQDVARALVAAWGGPEQNVAAVAQALGRDDLQREARGAQGLRDDSEG
CCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
TLLRVKLNGTGGAQRWTAYTALLIFPDRAFPATANVQGSAQAPNVLRIFSDFQCPYCKEL
CEEEEEECCCCCCCHHEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHH
WDTAHPKWAAQPNVYRVMHYHFPLSFHKNAEPAAIASECAAEQGKFWPYADLLFRHTAEW
HHCCCCCCCCCCCEEEEEEEEECEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TGLPSASAKFSEYAQAAGLNVAAFQTCLTSAAPKAVVRAQQAAGLKLGVQGTPTVYLNGV
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCEEEEEEE
QLRNYSDENELAAVRAVTAASPGAVEVIAARLKRF
EEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA