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The map label for this gene is gph [C]

Identifier: 94984796

GI number: 94984796

Start: 747817

End: 748506

Strand: Reverse

Name: gph [C]

Synonym: Dgeo_0689

Alternate gene names: 94984796

Gene position: 748506-747817 (Counterclockwise)

Preceding gene: 94984798

Following gene: 94984795

Centisome position: 30.34

GC content: 67.25

Gene sequence:

>690_bases
ATGAGCCACCCTGAACCAACTGCCCCTGCAGCCGCCCTGGACCCCAAGCGCCTGCGTGGGGTGCTGCTGGATGTGGACGG
CACCCTCATCGACTCGAATGACGCCCACGCCCGGGCCTGGGTGGAGGCGCTGCGCGAGGCGGGCTTCGAGCGGACCTTTG
AGGAGGTGCGCCCGCTGATCGGCATGGGCGGCGACCAGCTCATCCCCAGACTCACTGGGCTCGACAGCCAGAGCGAAGAG
GGCCAGCGGCTTACCCAGGGCTGGCTGCGGCACTTCAAGCCGCTCATCCCCACACTGCACGCCACACGGGGAGCGCGGGC
GCTGGTGCAGGGACTTCATGCACGCGGCCTGCAGGTGCTGCTCGCAACCAGCGGCGAGGCAGAGATCGTGGACGAGCTGC
TGAAACAAGCCCACCTGGATGACCTACAGCTCGAACGAGTGAGCAGCAGCGAGGTCGAAAGCAGCAAACCCGCCCCTGAT
TTGGTGCAGGCTGGACTGGAAAAGCTCGGGCTTCCCGCCGGGGAGGCCCTCCTGGTCGGAGACACGCCCTACGACGCTCA
GGCTGCGCACAAGGCAGGCGTCCCCTGCGTCCTGCTGCGCTGCGGTGGCAACACGGGGCTGGAGGAACATGCGCCCACCT
TGGATGATCCGCAGGCGCTCCTGGAGGTACTGGAGGGAACGAAAGGCTAA

Upstream 100 bases:

>100_bases
TGCGCGTCATAACCCAGTGTGCACTACCCCATGTTTGCCTGTGGAATGTATGAAAGCATCATGAAGGATACCGCCAAAGC
AGGGCGCGTAGCCTCAGCGA

Downstream 100 bases:

>100_bases
CCGTTTTCCCGCAGCAGGGTTAGGAGATCGGGGTGCCGCTCGCCTCCTGGATCATCAGGCTCCCGGCGCGGTGTCCCACG
GTTTCAAGCCTGCACGGCGG

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSHPEPTAPAAALDPKRLRGVLLDVDGTLIDSNDAHARAWVEALREAGFERTFEEVRPLIGMGGDQLIPRLTGLDSQSEE
GQRLTQGWLRHFKPLIPTLHATRGARALVQGLHARGLQVLLATSGEAEIVDELLKQAHLDDLQLERVSSSEVESSKPAPD
LVQAGLEKLGLPAGEALLVGDTPYDAQAAHKAGVPCVLLRCGGNTGLEEHAPTLDDPQALLEVLEGTKG

Sequences:

>Translated_229_residues
MSHPEPTAPAAALDPKRLRGVLLDVDGTLIDSNDAHARAWVEALREAGFERTFEEVRPLIGMGGDQLIPRLTGLDSQSEE
GQRLTQGWLRHFKPLIPTLHATRGARALVQGLHARGLQVLLATSGEAEIVDELLKQAHLDDLQLERVSSSEVESSKPAPD
LVQAGLEKLGLPAGEALLVGDTPYDAQAAHKAGVPCVLLRCGGNTGLEEHAPTLDDPQALLEVLEGTKG
>Mature_228_residues
SHPEPTAPAAALDPKRLRGVLLDVDGTLIDSNDAHARAWVEALREAGFERTFEEVRPLIGMGGDQLIPRLTGLDSQSEEG
QRLTQGWLRHFKPLIPTLHATRGARALVQGLHARGLQVLLATSGEAEIVDELLKQAHLDDLQLERVSSSEVESSKPAPDL
VQAGLEKLGLPAGEALLVGDTPYDAQAAHKAGVPCVLLRCGGNTGLEEHAPTLDDPQALLEVLEGTKG

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24433; Mature: 24302

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPEPTAPAAALDPKRLRGVLLDVDGTLIDSNDAHARAWVEALREAGFERTFEEVRPLI
CCCCCCCCCCCCCCHHHHCEEEEECCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
GMGGDQLIPRLTGLDSQSEEGQRLTQGWLRHFKPLIPTLHATRGARALVQGLHARGLQVL
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LATSGEAEIVDELLKQAHLDDLQLERVSSSEVESSKPAPDLVQAGLEKLGLPAGEALLVG
EECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEC
DTPYDAQAAHKAGVPCVLLRCGGNTGLEEHAPTLDDPQALLEVLEGTKG
CCCCCHHHHHHCCCCEEEEEECCCCCHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SHPEPTAPAAALDPKRLRGVLLDVDGTLIDSNDAHARAWVEALREAGFERTFEEVRPLI
CCCCCCCCCCCCCHHHHCEEEEECCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
GMGGDQLIPRLTGLDSQSEEGQRLTQGWLRHFKPLIPTLHATRGARALVQGLHARGLQVL
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LATSGEAEIVDELLKQAHLDDLQLERVSSSEVESSKPAPDLVQAGLEKLGLPAGEALLVG
EECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEC
DTPYDAQAAHKAGVPCVLLRCGGNTGLEEHAPTLDDPQALLEVLEGTKG
CCCCCHHHHHHCCCCEEEEEECCCCCHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA