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The map label for this gene is argC [H]

Identifier: 94984792

GI number: 94984792

Start: 741621

End: 742670

Strand: Reverse

Name: argC [H]

Synonym: Dgeo_0685

Alternate gene names: 94984792

Gene position: 742670-741621 (Counterclockwise)

Preceding gene: 94984793

Following gene: 94984790

Centisome position: 30.1

GC content: 66.86

Gene sequence:

>1050_bases
ATGACTGGTTCTGAACGACTTTCCGTGGCCATCGTGGGCGGCTCGGGTTATGCGGGCGGGGAGTTCCTGCGGCTGGCGCT
GGGGCACCCGTACCTGAACGTCACGCAGGTGACGAGCGAGCGCAGCGCGGGTCAGCCTGTGGCGCTGGTGCATCCCAACC
TGCGCGGGCGCACGAACCTGAAGTTTCGCCGGGCCGCCGAGCTGGAGGAAACCGACATCCTGGTGTTGGCCCTGCCACAC
GGCAGCGCGGCCAAGCGGCTGGCCGAATTCGAGGGCAAGGCGCGGGTGATCGTGGACCTCTCCGCCGACTTCCGGCTCAA
GGATCCCGAACTTTACCGGCAGTACTACGGTGAGGATCACCCAACGCCCGAGCGGTTGAACGACTGGGTGTACGGCAATC
CCGAACTGCACCGCGAGGAGTTGCGCGGCGCGACCCGCATTGCCTGCGCGGGATGCTTTGCCACCAGCGTGATCCTGCCG
CTGTATCCGCTGCTTAAGCTGGGCGTGCTGCTTCCCAAGGACATCATCGCAACCGGACTGGTCGGCTCGAGCGCGGCGGG
CGCCACACCCACCGAGGCGAGCCACCATCCGGAGCGCGCCGGAAGCCTGCGGGTGTACAAGCCGGTCGGGCACCGCCACA
CGGCCGAGGCAATCCAGGAGTTGCCGGGCCGCTTTCCACTGCACCTCACCGCCATCAGTACGCCACGCGTGCGCGGCATT
CTCACCACCATCCAGGCCTGGATTCCCGACGGCTACAGCGACCGCGACGTGTGGGGAGCCTACCGCGAGGTCTACGCGGC
CGAACCGTTCATCCGCATCGTAAAGGTGGCCCGTGGCATCCACCGCTATCCCGATCCCATGCTGCTCGACGGCACCAACT
ACTGCGACCTGGGCTTCGAGATGGACCCGGACACGGGCCGAGTGGTGCTGATGAGCGCCATTGACAATCTGGTCAAGGGC
ACGGCGGGGCACGCCATCCAGAGCCTCAACATCGCGCACGGCTGGCCTGAGACCTGCGGGTTGGAGTTTGCGGGACTCCA
CCCGGCCTGA

Upstream 100 bases:

>100_bases
CGGGCAAGCGGCTACCCCACGACAAGCAGGATTGGTTGTGCGCTTGTCGTATGCAAACTTCCTTCCCTCCTCACCTACAA
TTTGTGATGTACTGAGCCGC

Downstream 100 bases:

>100_bases
GAGCGGTGGGCGCTCAGGCGGGCGGCGGCAGCCGCACCACACTCAGCATATAACGTCCCAAGGCATGAATAGCCCGGTAA
AAGTGGTCGAAGTCGATGGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTGSERLSVAIVGGSGYAGGEFLRLALGHPYLNVTQVTSERSAGQPVALVHPNLRGRTNLKFRRAAELEETDILVLALPH
GSAAKRLAEFEGKARVIVDLSADFRLKDPELYRQYYGEDHPTPERLNDWVYGNPELHREELRGATRIACAGCFATSVILP
LYPLLKLGVLLPKDIIATGLVGSSAAGATPTEASHHPERAGSLRVYKPVGHRHTAEAIQELPGRFPLHLTAISTPRVRGI
LTTIQAWIPDGYSDRDVWGAYREVYAAEPFIRIVKVARGIHRYPDPMLLDGTNYCDLGFEMDPDTGRVVLMSAIDNLVKG
TAGHAIQSLNIAHGWPETCGLEFAGLHPA

Sequences:

>Translated_349_residues
MTGSERLSVAIVGGSGYAGGEFLRLALGHPYLNVTQVTSERSAGQPVALVHPNLRGRTNLKFRRAAELEETDILVLALPH
GSAAKRLAEFEGKARVIVDLSADFRLKDPELYRQYYGEDHPTPERLNDWVYGNPELHREELRGATRIACAGCFATSVILP
LYPLLKLGVLLPKDIIATGLVGSSAAGATPTEASHHPERAGSLRVYKPVGHRHTAEAIQELPGRFPLHLTAISTPRVRGI
LTTIQAWIPDGYSDRDVWGAYREVYAAEPFIRIVKVARGIHRYPDPMLLDGTNYCDLGFEMDPDTGRVVLMSAIDNLVKG
TAGHAIQSLNIAHGWPETCGLEFAGLHPA
>Mature_348_residues
TGSERLSVAIVGGSGYAGGEFLRLALGHPYLNVTQVTSERSAGQPVALVHPNLRGRTNLKFRRAAELEETDILVLALPHG
SAAKRLAEFEGKARVIVDLSADFRLKDPELYRQYYGEDHPTPERLNDWVYGNPELHREELRGATRIACAGCFATSVILPL
YPLLKLGVLLPKDIIATGLVGSSAAGATPTEASHHPERAGSLRVYKPVGHRHTAEAIQELPGRFPLHLTAISTPRVRGIL
TTIQAWIPDGYSDRDVWGAYREVYAAEPFIRIVKVARGIHRYPDPMLLDGTNYCDLGFEMDPDTGRVVLMSAIDNLVKGT
AGHAIQSLNIAHGWPETCGLEFAGLHPA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=347, Percent_Identity=31.1239193083574, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320913, Length=349, Percent_Identity=28.9398280802292, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 38089; Mature: 37958

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSERLSVAIVGGSGYAGGEFLRLALGHPYLNVTQVTSERSAGQPVALVHPNLRGRTNL
CCCCCEEEEEEECCCCCCCHHEEEEECCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCC
KFRRAAELEETDILVLALPHGSAAKRLAEFEGKARVIVDLSADFRLKDPELYRQYYGEDH
EEHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCEECCHHHHHHHCCCCC
PTPERLNDWVYGNPELHREELRGATRIACAGCFATSVILPLYPLLKLGVLLPKDIIATGL
CCHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
VGSSAAGATPTEASHHPERAGSLRVYKPVGHRHTAEAIQELPGRFPLHLTAISTPRVRGI
CCCCCCCCCCCCCCCCCHHCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHH
LTTIQAWIPDGYSDRDVWGAYREVYAAEPFIRIVKVARGIHRYPDPMLLDGTNYCDLGFE
HHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCEEECCCE
MDPDTGRVVLMSAIDNLVKGTAGHAIQSLNIAHGWPETCGLEFAGLHPA
ECCCCCCEEHHHHHHHHHCCCCCHHHHCCCCCCCCCHHCCCEECCCCCC
>Mature Secondary Structure 
TGSERLSVAIVGGSGYAGGEFLRLALGHPYLNVTQVTSERSAGQPVALVHPNLRGRTNL
CCCCEEEEEEECCCCCCCHHEEEEECCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCC
KFRRAAELEETDILVLALPHGSAAKRLAEFEGKARVIVDLSADFRLKDPELYRQYYGEDH
EEHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCEECCHHHHHHHCCCCC
PTPERLNDWVYGNPELHREELRGATRIACAGCFATSVILPLYPLLKLGVLLPKDIIATGL
CCHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
VGSSAAGATPTEASHHPERAGSLRVYKPVGHRHTAEAIQELPGRFPLHLTAISTPRVRGI
CCCCCCCCCCCCCCCCCHHCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHH
LTTIQAWIPDGYSDRDVWGAYREVYAAEPFIRIVKVARGIHRYPDPMLLDGTNYCDLGFE
HHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCEEECCCE
MDPDTGRVVLMSAIDNLVKGTAGHAIQSLNIAHGWPETCGLEFAGLHPA
ECCCCCCEEHHHHHHHHHCCCCCHHHHCCCCCCCCCHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]