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The map label for this gene is truD [H]

Identifier: 94984701

GI number: 94984701

Start: 633557

End: 634636

Strand: Reverse

Name: truD [H]

Synonym: Dgeo_0594

Alternate gene names: 94984701

Gene position: 634636-633557 (Counterclockwise)

Preceding gene: 94984702

Following gene: 94984700

Centisome position: 25.72

GC content: 68.33

Gene sequence:

>1080_bases
ATGGTAGGCCCCATCGTGAGTCTGGTTTTCGAGTGGTCGGCGCTGGCCGCGCTGACGGAGACGCCCGGAACAGGGGGTGA
GTTGCGGGCCGTGCCGGAGGATTTCCGGGTCGAAGAAGTGCCCGCCTATCCCCTCTCGGGCGAGGGCGAGCATCTCTTCC
TGCATCTGGAGAAAAGGGGGCATACCACCGCGCACGTGCTGCGCGAGCTGTGCGCGCAGGTGGGCGTGCGGGACCGTGAC
GTGGGGGTGGCTGGGCTGAAGGACCGCCATGCGGTGACGACCCAGTGGATCAGCGTGCCCGCGCGGTACGAGGAGCGCCT
CAGCCACTTCGCGTTGGAAGGCGTGCGGGTGCTGGAGACGCGGCGGCATGGCAACAAGCTGGGGCTGGGGCACCTGCGCG
GCAACCGCTTCGTGGTGCGGGTGCGGAAGGCAGCGGGGACAGCGGACCAGGCCGCCCTGACGCTGGCGCTGCTTACCCGG
CACGGCGTCCCCAACTACTTCGGTCCCCAGCGCTTCGGGCTGAGGGGCCTGAACGCCGAGGAGGGATTGAACGTGCTGCG
CGGCGAATCCCGCCTGCGCGACCCGCGTGTGCGCCGCTTTCTGACCACCAGCGTGCAGAGCCTGGTGTTTAACCGCTTTC
TCAGCCTGCGCCTGGAGCGGGGATTGTTCGAGCGGCTGGTGGCGGGCGACATGGCCAAAAAGCACGACACAGGGGGCGTC
TTCCTGGTTGAGGACGCGGCGGCAGAGTCTCTCCGCGCCGAGCGGGGTGAGGTGAGCGCGACCGGCACCCTCTTTGGCCG
GAAGGTGAAGCCGCTCACGCTGGACGCGGGTGAGCTGGAGCGCGAGGCGCTCGCGGCGTTTGGCCTCACCCCCGAAGTCT
TCGCCTCGCGCCGAGGAGACCGCCGCCTCACACGGGTGTTTCCTGAGAATGCCGAGGTCCGCCCCAAAGAGGACGGCTAT
ACGGTGGCCTTTACGCTCCCCAAAGGGAGTTTTGCCACCAGCGTCCTGCGCGAACTGATGAAGACCGACGTGGACGCGGC
GGCGGGCGAGCCAGACGAGAGCAGCGAGGACAACGAATGA

Upstream 100 bases:

>100_bases
CCGACTGGACGCCGCAGGCCTATGCCGATCGGCGCGTGCTCAACTGAGGGAAGGGGGCTTCCCGCCTCTGACTCTCATAC
CCCCCTCGGGGTCCTGACGT

Downstream 100 bases:

>100_bases
GAAGGGCAGGACTGGCCGTTCTCGTCACGCTGTTGGGAGCAGCCCTTGCGGCGCGCCTGCCCGCGGCCCAGGTGGGCCTG
CGGCCCTCATTTGCCGGAGC

Product: pseudouridylate synthase

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MVGPIVSLVFEWSALAALTETPGTGGELRAVPEDFRVEEVPAYPLSGEGEHLFLHLEKRGHTTAHVLRELCAQVGVRDRD
VGVAGLKDRHAVTTQWISVPARYEERLSHFALEGVRVLETRRHGNKLGLGHLRGNRFVVRVRKAAGTADQAALTLALLTR
HGVPNYFGPQRFGLRGLNAEEGLNVLRGESRLRDPRVRRFLTTSVQSLVFNRFLSLRLERGLFERLVAGDMAKKHDTGGV
FLVEDAAAESLRAERGEVSATGTLFGRKVKPLTLDAGELEREALAAFGLTPEVFASRRGDRRLTRVFPENAEVRPKEDGY
TVAFTLPKGSFATSVLRELMKTDVDAAAGEPDESSEDNE

Sequences:

>Translated_359_residues
MVGPIVSLVFEWSALAALTETPGTGGELRAVPEDFRVEEVPAYPLSGEGEHLFLHLEKRGHTTAHVLRELCAQVGVRDRD
VGVAGLKDRHAVTTQWISVPARYEERLSHFALEGVRVLETRRHGNKLGLGHLRGNRFVVRVRKAAGTADQAALTLALLTR
HGVPNYFGPQRFGLRGLNAEEGLNVLRGESRLRDPRVRRFLTTSVQSLVFNRFLSLRLERGLFERLVAGDMAKKHDTGGV
FLVEDAAAESLRAERGEVSATGTLFGRKVKPLTLDAGELEREALAAFGLTPEVFASRRGDRRLTRVFPENAEVRPKEDGY
TVAFTLPKGSFATSVLRELMKTDVDAAAGEPDESSEDNE
>Mature_359_residues
MVGPIVSLVFEWSALAALTETPGTGGELRAVPEDFRVEEVPAYPLSGEGEHLFLHLEKRGHTTAHVLRELCAQVGVRDRD
VGVAGLKDRHAVTTQWISVPARYEERLSHFALEGVRVLETRRHGNKLGLGHLRGNRFVVRVRKAAGTADQAALTLALLTR
HGVPNYFGPQRFGLRGLNAEEGLNVLRGESRLRDPRVRRFLTTSVQSLVFNRFLSLRLERGLFERLVAGDMAKKHDTGGV
FLVEDAAAESLRAERGEVSATGTLFGRKVKPLTLDAGELEREALAAFGLTPEVFASRRGDRRLTRVFPENAEVRPKEDGY
TVAFTLPKGSFATSVLRELMKTDVDAAAGEPDESSEDNE

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=346, Percent_Identity=33.8150289017341, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 39552; Mature: 39552

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGPIVSLVFEWSALAALTETPGTGGELRAVPEDFRVEEVPAYPLSGEGEHLFLHLEKRG
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCC
HTTAHVLRELCAQVGVRDRDVGVAGLKDRHAVTTQWISVPARYEERLSHFALEGVRVLET
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RRHGNKLGLGHLRGNRFVVRVRKAAGTADQAALTLALLTRHGVPNYFGPQRFGLRGLNAE
HHCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHH
EGLNVLRGESRLRDPRVRRFLTTSVQSLVFNRFLSLRLERGLFERLVAGDMAKKHDTGGV
HHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FLVEDAAAESLRAERGEVSATGTLFGRKVKPLTLDAGELEREALAAFGLTPEVFASRRGD
EEEECHHHHHHHHHCCCCEECCCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHCCCCC
RRLTRVFPENAEVRPKEDGYTVAFTLPKGSFATSVLRELMKTDVDAAAGEPDESSEDNE
CHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVGPIVSLVFEWSALAALTETPGTGGELRAVPEDFRVEEVPAYPLSGEGEHLFLHLEKRG
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCC
HTTAHVLRELCAQVGVRDRDVGVAGLKDRHAVTTQWISVPARYEERLSHFALEGVRVLET
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RRHGNKLGLGHLRGNRFVVRVRKAAGTADQAALTLALLTRHGVPNYFGPQRFGLRGLNAE
HHCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHH
EGLNVLRGESRLRDPRVRRFLTTSVQSLVFNRFLSLRLERGLFERLVAGDMAKKHDTGGV
HHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FLVEDAAAESLRAERGEVSATGTLFGRKVKPLTLDAGELEREALAAFGLTPEVFASRRGD
EEEECHHHHHHHHHCCCCEECCCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHCCCCC
RRLTRVFPENAEVRPKEDGYTVAFTLPKGSFATSVLRELMKTDVDAAAGEPDESSEDNE
CHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]