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The map label for this gene is xpt

Identifier: 94984598

GI number: 94984598

Start: 508858

End: 509466

Strand: Reverse

Name: xpt

Synonym: Dgeo_0491

Alternate gene names: 94984598

Gene position: 509466-508858 (Counterclockwise)

Preceding gene: 94984599

Following gene: 94984597

Centisome position: 20.65

GC content: 65.02

Gene sequence:

>609_bases
ATGCAGGCGTTGGTCGAGGCGATTCGGGAGCGGGGCATGATTCTGCCCGGCGGCATGCTCAAGGTGGATGGGCTGATCAA
CCATCAGCTTCTTCCTCAGCTCACGCGCGAGATGGGCGAGCGGTTTGCGGCGGGGTTCGCGCCCCTTAACCCCAACAAGG
TCGTGACGATCGAGGTCAGCGGGATCGCACCCGCGCTCGCGACAGCTCTGGCGCTGAACGTGCCGCTGGTCTACGCGCGC
AAGAAAAAACCCATCACCATGCAGGAACCCACCTTCACCGCGCAGTCCATCAGCCGGACCAAGGGCGGCGCCGTGGACCT
GTTCGTGAGCAGCGAGTATCTGGGGTCCGGGGACCGGGTGGTTGTGATCGACGATTTCCTGGCTTCTGGCGGCACGCTGC
GGGCCCTGGCCGGCATCATCGCGCTCAGCGGTGCCGAGCTGCTCGGTCTGGGGTGTGTGATCGAGAAGGGCTTTGAGGAA
GGCCGCGCCAAGCTGGCCGACCTGGGTGTACCGATCCTGACGCTGGCGAACATCCTCCGGATGAATGAGCAGGAGGGGAT
CGTGGTGGAGGCAGGGCTACAGGACCTGCCAAAGCAGCCGGCAGGCTGA

Upstream 100 bases:

>100_bases
TGAGCGAGCAAGAATACCTGCATTACATTCGCGAGTTGGGCTTCCGGCCGGAAATCAACGAGCTGTCAGGAACCTCTGGG
AGCGGGATACACTCGCGCTG

Downstream 100 bases:

>100_bases
CCGTTCTGCTCTGGGCACCAGGGATAAGAAAGCACCAGCTTCAACGTAAGCGTTTCTCAATCTGACGCTCAGATGAGCGG
CAGGGTGGCCTTCTAGGCTG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MQALVEAIRERGMILPGGMLKVDGLINHQLLPQLTREMGERFAAGFAPLNPNKVVTIEVSGIAPALATALALNVPLVYAR
KKKPITMQEPTFTAQSISRTKGGAVDLFVSSEYLGSGDRVVVIDDFLASGGTLRALAGIIALSGAELLGLGCVIEKGFEE
GRAKLADLGVPILTLANILRMNEQEGIVVEAGLQDLPKQPAG

Sequences:

>Translated_202_residues
MQALVEAIRERGMILPGGMLKVDGLINHQLLPQLTREMGERFAAGFAPLNPNKVVTIEVSGIAPALATALALNVPLVYAR
KKKPITMQEPTFTAQSISRTKGGAVDLFVSSEYLGSGDRVVVIDDFLASGGTLRALAGIIALSGAELLGLGCVIEKGFEE
GRAKLADLGVPILTLANILRMNEQEGIVVEAGLQDLPKQPAG
>Mature_202_residues
MQALVEAIRERGMILPGGMLKVDGLINHQLLPQLTREMGERFAAGFAPLNPNKVVTIEVSGIAPALATALALNVPLVYAR
KKKPITMQEPTFTAQSISRTKGGAVDLFVSSEYLGSGDRVVVIDDFLASGGTLRALAGIIALSGAELLGLGCVIEKGFEE
GRAKLADLGVPILTLANILRMNEQEGIVVEAGLQDLPKQPAG

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_DEIGD (Q1J141)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_603962.1
- ProteinModelPortal:   Q1J141
- SMR:   Q1J141
- STRING:   Q1J141
- GeneID:   4057922
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_0491
- NMPDR:   fig|68909.1.peg.792
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   DGEO319795:DGEO_0491-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21254; Mature: 21254

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALVEAIRERGMILPGGMLKVDGLINHQLLPQLTREMGERFAAGFAPLNPNKVVTIEVS
CHHHHHHHHHCCEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
GIAPALATALALNVPLVYARKKKPITMQEPTFTAQSISRTKGGAVDLFVSSEYLGSGDRV
CCHHHHHHHHHHCCCEEEECCCCCCEECCCCCCHHHHHHCCCCEEEEEEEHHHCCCCCEE
VVIDDFLASGGTLRALAGIIALSGAELLGLGCVIEKGFEEGRAKLADLGVPILTLANILR
EEEEHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
MNEQEGIVVEAGLQDLPKQPAG
CCCCCCEEEECCHHHCCCCCCC
>Mature Secondary Structure
MQALVEAIRERGMILPGGMLKVDGLINHQLLPQLTREMGERFAAGFAPLNPNKVVTIEVS
CHHHHHHHHHCCEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
GIAPALATALALNVPLVYARKKKPITMQEPTFTAQSISRTKGGAVDLFVSSEYLGSGDRV
CCHHHHHHHHHHCCCEEEECCCCCCEECCCCCCHHHHHHCCCCEEEEEEEHHHCCCCCEE
VVIDDFLASGGTLRALAGIIALSGAELLGLGCVIEKGFEEGRAKLADLGVPILTLANILR
EEEEHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
MNEQEGIVVEAGLQDLPKQPAG
CCCCCCEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA