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The map label for this gene is menC [H]

Identifier: 94984501

GI number: 94984501

Start: 398880

End: 399989

Strand: Reverse

Name: menC [H]

Synonym: Dgeo_0393

Alternate gene names: 94984501

Gene position: 399989-398880 (Counterclockwise)

Preceding gene: 94984508

Following gene: 94984500

Centisome position: 16.21

GC content: 65.5

Gene sequence:

>1110_bases
ATGCTCAGAATTGACGCCGCTGAAATCCTGCTGGTGCGCTTGCCCCTCAAGTTCCGTTTCGAGACGAGCTTCGGCGTGCA
GACCGAAAAGCTGGTGCCCCTGCTGGTGCTGCATGGAGACGGCGTGCAAGGCCTCAGCGAGGGCACGATGGAAGCGGCGC
CAATGTACCGCGAGGAAACCATCGCTGGAGCATTGAATCTGCTGCGCAAGGTCTTCTTGCCGCGTGTGCTGGGCCGTACC
TTTGCCAACCCACAGGCGGTGGACGCCGCACTCGGCAGCTTCCGGGGCAACCGGATGGCGCGGGCGATGGTGGAGATGGC
CGCCTGGGACCTGTGGGCCCGGACGCTCGGCGTACCGCTGGGGACACTGCTCGGCGGGAATAAACAGGAGGTCGAGGTTG
GGGTCAGCCTGGGCATTCAGGCAGACGAGGCCGCGACGGTGGAGGTGGTGGGACGCCACGTGGAGCAGGGGTACCGGCGA
ATCAAGCTCAAGATCAAGCCGGGATGGGACGTGCAGCCGGTGCAGGCGGTGCGGGAGGCTTTCCCCAATATTCGCCTCAC
GGTGGATGCCAACAGCGCCTATACCCTGGCGGACTCGGGACGGCTTGCCGCGCTGGATGCCTATGACCTGACGTATATCG
AGCAGCCGCTCGCGTGGGACGATCTCTTGGACCACGCTGAACTGCAACGCCGCCTGCGCACGCCCCTTTGCCTGGACGAA
AGCGTGGCGAGTGCGCCGGATGCCCGCAAGGGCCTTGCGCTGGGAGCAGGGCGGGTCATCAACGTGAAGGTCGCGCGGGT
GGGCGGACACGCCGAAGCACGCCGGGTGCACGACGTGGCCGAAAGTTTCGGGGCGCCGGTCTGGTGCGGGGGGATGCTGG
AAAGCGGCGTGGGCCGGGCACACAACATCCACCTCTCGACGCTGCCGAACTTCAGGCTGCCGGGCGACACCAGCAGTGCC
AGCCGCTACTGGGCGACCGATGTGGTGAATGAGGCGCTGGAGGCAAAAAACGGGCTGATGCCGGTGCCTCAGGGACCGGG
CATTGGCGTGACACTGAATCGGGACTTTATCGCGAGCGTATCGGAACTGGACGAGGAGTACCGAGCTTGA

Upstream 100 bases:

>100_bases
TCAACCCCCCCCCCGCTTCAGCATCATTTCGGGAGATGAAAACTTCGCCCCAGCCACATCTCCTCTCCAGCCTCTGCCCG
CAGCCCAGGCATACTGAGGC

Downstream 100 bases:

>100_bases
GCCAAGCCAGTTTCCGCCCCTTCGTCATCCGCGACGTAACGGACCCTTGGGAAATGCGCGCCTTAGAGGACGTGCAGGTG
CAGGCGTGGGGGTACAGCGA

Product: mandelate racemase/muconate lactonizing-like protein

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLRIDAAEILLVRLPLKFRFETSFGVQTEKLVPLLVLHGDGVQGLSEGTMEAAPMYREETIAGALNLLRKVFLPRVLGRT
FANPQAVDAALGSFRGNRMARAMVEMAAWDLWARTLGVPLGTLLGGNKQEVEVGVSLGIQADEAATVEVVGRHVEQGYRR
IKLKIKPGWDVQPVQAVREAFPNIRLTVDANSAYTLADSGRLAALDAYDLTYIEQPLAWDDLLDHAELQRRLRTPLCLDE
SVASAPDARKGLALGAGRVINVKVARVGGHAEARRVHDVAESFGAPVWCGGMLESGVGRAHNIHLSTLPNFRLPGDTSSA
SRYWATDVVNEALEAKNGLMPVPQGPGIGVTLNRDFIASVSELDEEYRA

Sequences:

>Translated_369_residues
MLRIDAAEILLVRLPLKFRFETSFGVQTEKLVPLLVLHGDGVQGLSEGTMEAAPMYREETIAGALNLLRKVFLPRVLGRT
FANPQAVDAALGSFRGNRMARAMVEMAAWDLWARTLGVPLGTLLGGNKQEVEVGVSLGIQADEAATVEVVGRHVEQGYRR
IKLKIKPGWDVQPVQAVREAFPNIRLTVDANSAYTLADSGRLAALDAYDLTYIEQPLAWDDLLDHAELQRRLRTPLCLDE
SVASAPDARKGLALGAGRVINVKVARVGGHAEARRVHDVAESFGAPVWCGGMLESGVGRAHNIHLSTLPNFRLPGDTSSA
SRYWATDVVNEALEAKNGLMPVPQGPGIGVTLNRDFIASVSELDEEYRA
>Mature_369_residues
MLRIDAAEILLVRLPLKFRFETSFGVQTEKLVPLLVLHGDGVQGLSEGTMEAAPMYREETIAGALNLLRKVFLPRVLGRT
FANPQAVDAALGSFRGNRMARAMVEMAAWDLWARTLGVPLGTLLGGNKQEVEVGVSLGIQADEAATVEVVGRHVEQGYRR
IKLKIKPGWDVQPVQAVREAFPNIRLTVDANSAYTLADSGRLAALDAYDLTYIEQPLAWDDLLDHAELQRRLRTPLCLDE
SVASAPDARKGLALGAGRVINVKVARVGGHAEARRVHDVAESFGAPVWCGGMLESGVGRAHNIHLSTLPNFRLPGDTSSA
SRYWATDVVNEALEAKNGLMPVPQGPGIGVTLNRDFIASVSELDEEYRA

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 40058; Mature: 40058

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIDAAEILLVRLPLKFRFETSFGVQTEKLVPLLVLHGDGVQGLSEGTMEAAPMYREET
CEEECHHHEEEEECCCEEEECCCCCCCHHCCCEEEEEECCCCCCCCCCCHHHCCCHHHHH
IAGALNLLRKVFLPRVLGRTFANPQAVDAALGSFRGNRMARAMVEMAAWDLWARTLGVPL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
GTLLGGNKQEVEVGVSLGIQADEAATVEVVGRHVEQGYRRIKLKIKPGWDVQPVQAVREA
HHHHCCCHHEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHH
FPNIRLTVDANSAYTLADSGRLAALDAYDLTYIEQPLAWDDLLDHAELQRRLRTPLCLDE
CCCEEEEEECCCEEEEECCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCH
SVASAPDARKGLALGAGRVINVKVARVGGHAEARRVHDVAESFGAPVWCGGMLESGVGRA
HHHCCCCCCCCCEECCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCEEECHHHHHCCCCC
HNIHLSTLPNFRLPGDTSSASRYWATDVVNEALEAKNGLMPVPQGPGIGVTLNRDFIASV
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHH
SELDEEYRA
HHHHHHHCC
>Mature Secondary Structure
MLRIDAAEILLVRLPLKFRFETSFGVQTEKLVPLLVLHGDGVQGLSEGTMEAAPMYREET
CEEECHHHEEEEECCCEEEECCCCCCCHHCCCEEEEEECCCCCCCCCCCHHHCCCHHHHH
IAGALNLLRKVFLPRVLGRTFANPQAVDAALGSFRGNRMARAMVEMAAWDLWARTLGVPL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
GTLLGGNKQEVEVGVSLGIQADEAATVEVVGRHVEQGYRRIKLKIKPGWDVQPVQAVREA
HHHHCCCHHEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHH
FPNIRLTVDANSAYTLADSGRLAALDAYDLTYIEQPLAWDDLLDHAELQRRLRTPLCLDE
CCCEEEEEECCCEEEEECCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCH
SVASAPDARKGLALGAGRVINVKVARVGGHAEARRVHDVAESFGAPVWCGGMLESGVGRA
HHHCCCCCCCCCEECCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCEEECHHHHHCCCCC
HNIHLSTLPNFRLPGDTSSASRYWATDVVNEALEAKNGLMPVPQGPGIGVTLNRDFIASV
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHH
SELDEEYRA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]