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The map label for this gene is yeiI [H]

Identifier: 94984466

GI number: 94984466

Start: 363341

End: 364474

Strand: Reverse

Name: yeiI [H]

Synonym: Dgeo_0358

Alternate gene names: 94984466

Gene position: 364474-363341 (Counterclockwise)

Preceding gene: 94984467

Following gene: 94984465

Centisome position: 14.77

GC content: 71.69

Gene sequence:

>1134_bases
ATGCCGCTGACCGAGCGCGAACGCGCCCTCCTCAACCTGATTCGCGAGGCCCCCCTCAGCACCCCCGCAGAACTGGCCCG
CCGCCTGGGGACCTCGCGCGCGGCGGTCAATGTGCACGTGAGCAACCTGATTCGCAAGGGTGCACTGCTGGGGCGTGGCT
ACGTCGTGGCGCCGGAGCAGGAGGCACGGGTGGTCGTGGTCGGCGGCGCGAACGTGGACATCAAGGCGCGAACGCTCGCG
CCCGCTGTCTCTGGCACCAGCAATCCGGGGATGACCCGTCAGGCCGCAGGGGGTGTGGCCCGCAACATCGCGGAGAACTT
GGCCCGGCTGGGGATCCAGACGCACCTGATCACGGCGCTTGGGCGGGACGCGCCCGGCGACCTGCTGCTGCGCGAAACGG
AGGCGGCGGGTGTGGACATGCGAAGTGTGCTGCGCCTGGACGCCCCCACCGGCACCTACACGGCCGTGCTGGACAATAGC
GGCGAGCTGCTGATTGCGGTCGCGGCGATGGAGGTGACGGCTGCCCTGACCCCGGCAGCCCTGAACGAACGTCGCGGCCT
GCTCCAGCACGCGAGCTGGGTGGTCGCGGACGGGAACCTCAGCGCAGAAACGCTGACCCATCTGCTCACCCTCTGCCGGG
AAGCGGGCGTGCCCGTGACCTTTGAGCCGGTCAGTGTGCCGAAGGCCGCCCACCTCCTCCCCGCACTGCATTCCGGACTC
GCGCCGCACACCGTCACGCCGAACGTCGCGGAACTTGCCGCGCTCACGAGCCGGGACGTGGCCGACACGCCCGCGGCGCT
CGGAGCAGCTGCGCAGGAGCTGCATGCGCGGGGCGTCCAGACCGTCTGGGTGCGCCGGGGCGACCGCGGCAGCCTGCTGT
CAACCCCGGAAGGCGTTACCGAACTCCCCGCTCTCCCCGCCCAGGTCGCCGACGTGACCGGCGCAGGCGACGCGATGCTC
GCCGCCTACCTCGCCGCCCTGCTGGAGGGCCATTCTCCCGCCGAGGCCGCCCGTCACGGCCACGCCGCCGCTGCGCTGAC
GGTCGAGAGTCCTCATACCGTCTCCCCTACCCTCACCCCCGCTGCCCTTAGAGCGCGGCTGGGAAGCCCTGAGGCCGCGG
ACCGTGAGCGCTAA

Upstream 100 bases:

>100_bases
GCCGTACTGAAGCTTCCTTAAAACCGGGCAAGGCGTTATCCCCACCAGGAACCACGCCCTCTTGCTTCATTCCGATAAAA
ACCTTTACTCTAATTAAGCC

Downstream 100 bases:

>100_bases
CCGAAATCCTTGCGTTTCGTCCCCGCTTTCCTTCTGACAGCTCAGGTCTCAAAGCCTTACACCGCACCCCAAAGGAGTCC
TCATGCTCACCCCCATTCCC

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MPLTERERALLNLIREAPLSTPAELARRLGTSRAAVNVHVSNLIRKGALLGRGYVVAPEQEARVVVVGGANVDIKARTLA
PAVSGTSNPGMTRQAAGGVARNIAENLARLGIQTHLITALGRDAPGDLLLRETEAAGVDMRSVLRLDAPTGTYTAVLDNS
GELLIAVAAMEVTAALTPAALNERRGLLQHASWVVADGNLSAETLTHLLTLCREAGVPVTFEPVSVPKAAHLLPALHSGL
APHTVTPNVAELAALTSRDVADTPAALGAAAQELHARGVQTVWVRRGDRGSLLSTPEGVTELPALPAQVADVTGAGDAML
AAYLAALLEGHSPAEAARHGHAAAALTVESPHTVSPTLTPAALRARLGSPEAADRER

Sequences:

>Translated_377_residues
MPLTERERALLNLIREAPLSTPAELARRLGTSRAAVNVHVSNLIRKGALLGRGYVVAPEQEARVVVVGGANVDIKARTLA
PAVSGTSNPGMTRQAAGGVARNIAENLARLGIQTHLITALGRDAPGDLLLRETEAAGVDMRSVLRLDAPTGTYTAVLDNS
GELLIAVAAMEVTAALTPAALNERRGLLQHASWVVADGNLSAETLTHLLTLCREAGVPVTFEPVSVPKAAHLLPALHSGL
APHTVTPNVAELAALTSRDVADTPAALGAAAQELHARGVQTVWVRRGDRGSLLSTPEGVTELPALPAQVADVTGAGDAML
AAYLAALLEGHSPAEAARHGHAAAALTVESPHTVSPTLTPAALRARLGSPEAADRER
>Mature_376_residues
PLTERERALLNLIREAPLSTPAELARRLGTSRAAVNVHVSNLIRKGALLGRGYVVAPEQEARVVVVGGANVDIKARTLAP
AVSGTSNPGMTRQAAGGVARNIAENLARLGIQTHLITALGRDAPGDLLLRETEAAGVDMRSVLRLDAPTGTYTAVLDNSG
ELLIAVAAMEVTAALTPAALNERRGLLQHASWVVADGNLSAETLTHLLTLCREAGVPVTFEPVSVPKAAHLLPALHSGLA
PHTVTPNVAELAALTSRDVADTPAALGAAAQELHARGVQTVWVRRGDRGSLLSTPEGVTELPALPAQVADVTGAGDAMLA
AYLAALLEGHSPAEAARHGHAAAALTVESPHTVSPTLTPAALRARLGSPEAADRER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=237, Percent_Identity=28.2700421940928, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788484, Length=359, Percent_Identity=36.4902506963788, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1788491, Length=310, Percent_Identity=32.258064516129, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081971, Length=297, Percent_Identity=26.9360269360269, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082281, Length=290, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789432, Length=283, Percent_Identity=27.9151943462898, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147470, Length=322, Percent_Identity=25.4658385093168, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24580669, Length=323, Percent_Identity=26.0061919504644, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 38915; Mature: 38784

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTERERALLNLIREAPLSTPAELARRLGTSRAAVNVHVSNLIRKGALLGRGYVVAPEQ
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCEEECCCC
EARVVVVGGANVDIKARTLAPAVSGTSNPGMTRQAAGGVARNIAENLARLGIQTHLITAL
CCEEEEEECCCCEEEEHHHCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRDAPGDLLLRETEAAGVDMRSVLRLDAPTGTYTAVLDNSGELLIAVAAMEVTAALTPAA
CCCCCCCEEEEECCCCCCCHHHHHEECCCCCCEEEEEECCCCEEEEEEHHHHHHHHCHHH
LNERRGLLQHASWVVADGNLSAETLTHLLTLCREAGVPVTFEPVSVPKAAHLLPALHSGL
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCC
APHTVTPNVAELAALTSRDVADTPAALGAAAQELHARGVQTVWVRRGDRGSLLSTPEGVT
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCH
ELPALPAQVADVTGAGDAMLAAYLAALLEGHSPAEAARHGHAAAALTVESPHTVSPTLTP
HCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCH
AALRARLGSPEAADRER
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PLTERERALLNLIREAPLSTPAELARRLGTSRAAVNVHVSNLIRKGALLGRGYVVAPEQ
CCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCEEECCCC
EARVVVVGGANVDIKARTLAPAVSGTSNPGMTRQAAGGVARNIAENLARLGIQTHLITAL
CCEEEEEECCCCEEEEHHHCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRDAPGDLLLRETEAAGVDMRSVLRLDAPTGTYTAVLDNSGELLIAVAAMEVTAALTPAA
CCCCCCCEEEEECCCCCCCHHHHHEECCCCCCEEEEEECCCCEEEEEEHHHHHHHHCHHH
LNERRGLLQHASWVVADGNLSAETLTHLLTLCREAGVPVTFEPVSVPKAAHLLPALHSGL
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCC
APHTVTPNVAELAALTSRDVADTPAALGAAAQELHARGVQTVWVRRGDRGSLLSTPEGVT
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCH
ELPALPAQVADVTGAGDAMLAAYLAALLEGHSPAEAARHGHAAAALTVESPHTVSPTLTP
HCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCH
AALRARLGSPEAADRER
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2460435 [H]