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The map label for this gene is lacA [C]

Identifier: 94984366

GI number: 94984366

Start: 248706

End: 249626

Strand: Reverse

Name: lacA [C]

Synonym: Dgeo_0258

Alternate gene names: 94984366

Gene position: 249626-248706 (Counterclockwise)

Preceding gene: 94984367

Following gene: 94984365

Centisome position: 10.12

GC content: 64.93

Gene sequence:

>921_bases
ATGGCGACAGGCGCAACCCGCGCTACAGTGGCGGGCGTGACGTGGCTGAAGCCGGTGAGCATCAATGCAGACGCGCAGGG
GGCGTATCACGAGTTTCTGCGTGACCTGGAGGCCCGTCTTTTGGATCCGCAGACGGACCGGTACGCGCTGGCCCGCGAGG
TGCTGGCCCAGGCGATGTATGGGCGCGAGTACGGGCAACTCCTCGCGGACGCACCGCTGGCTGCCCTCAACCTCGACGCG
CACAATGTGACCTTTGAGGCCGAGTACTACATGGCGACGGACCCCGAGAAGTTCGCGCCGGTCAAGCCGCTGCTGTGGTT
GTGGAAGAACCTGGATCTCACGCCGATCGGGCAGAACCCGGTGCTGGGCATTCCCATCCGGCGGGTACTGGCCGAGCGAA
TCTTCAAGCGGGTGGGCCGCAATTTCAAATGCTGGCAAAACGTCGAATTCAGCGTGGGCTACAACATGGAGGTCGGCAAC
GACGTGGTAGTCCACCGCTACGTGCTGCTCGACGACATCGGCGGAATCGAGCTTCAGGACAATGCCTCTGTCAGCGACTA
CGTGAACATCTACAGCCACACCCACTCTGTGCTCGATGGTCCGGACGTGACCCTGCGGCGCACGGTGATCGGCCGCGGCG
CGCGGATCACCTACCACTCGACGGTTCTGGCGGGCAGCGTGGTCAGCGACGACGCGATGCTCGCCACCCACGCCCTGCTG
CGCGGGGACATCCCACCGCACGGCATCGCAATGGGTGTGCCTGCCAAGGTCACCCGCTACAAACGGCGCGAACCCTGGGC
CTACAGCGTGGATTCCCGCACCTACCCCCACGACCCCGGTCGCAAAGCCAACCCGGCCTTTCCTGACCCCACGCCCAACC
AGACGCGCAAGCCCACTCTGGAAGAGACGGGGGGGAGCTAA

Upstream 100 bases:

>100_bases
CAGCACGGGACACGCCGCACCGCTCCGCATCGGTACGCTGTTTTCCGGATCTGTCTGCGCAAGAAGACCTCAGGTGGTTT
TGGAAACTGCTTTAAACTCT

Downstream 100 bases:

>100_bases
ATGCGAAGCGGCACAAGCGCTTAGACTGGGTGCATGACCAAGCGCAGCAAGGTGTTCGTACCCGCCGTCGTGACGGTGGC
GACGGTCGGCGTGGCAGCCG

Product: acetyltransferase

Products: CoA; aacetyl-beta-D-galactoside [C]

Alternate protein names: Transferase Hexapeptide Repeat Containing Protein; Maltose Transacetylase; O-Acetyltransferase; Hexapaptide Repeat-Containing Transferase; Acetyltransferase-Like; Acetyltransferase-Like Protein

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MATGATRATVAGVTWLKPVSINADAQGAYHEFLRDLEARLLDPQTDRYALAREVLAQAMYGREYGQLLADAPLAALNLDA
HNVTFEAEYYMATDPEKFAPVKPLLWLWKNLDLTPIGQNPVLGIPIRRVLAERIFKRVGRNFKCWQNVEFSVGYNMEVGN
DVVVHRYVLLDDIGGIELQDNASVSDYVNIYSHTHSVLDGPDVTLRRTVIGRGARITYHSTVLAGSVVSDDAMLATHALL
RGDIPPHGIAMGVPAKVTRYKRREPWAYSVDSRTYPHDPGRKANPAFPDPTPNQTRKPTLEETGGS

Sequences:

>Translated_306_residues
MATGATRATVAGVTWLKPVSINADAQGAYHEFLRDLEARLLDPQTDRYALAREVLAQAMYGREYGQLLADAPLAALNLDA
HNVTFEAEYYMATDPEKFAPVKPLLWLWKNLDLTPIGQNPVLGIPIRRVLAERIFKRVGRNFKCWQNVEFSVGYNMEVGN
DVVVHRYVLLDDIGGIELQDNASVSDYVNIYSHTHSVLDGPDVTLRRTVIGRGARITYHSTVLAGSVVSDDAMLATHALL
RGDIPPHGIAMGVPAKVTRYKRREPWAYSVDSRTYPHDPGRKANPAFPDPTPNQTRKPTLEETGGS
>Mature_305_residues
ATGATRATVAGVTWLKPVSINADAQGAYHEFLRDLEARLLDPQTDRYALAREVLAQAMYGREYGQLLADAPLAALNLDAH
NVTFEAEYYMATDPEKFAPVKPLLWLWKNLDLTPIGQNPVLGIPIRRVLAERIFKRVGRNFKCWQNVEFSVGYNMEVGND
VVVHRYVLLDDIGGIELQDNASVSDYVNIYSHTHSVLDGPDVTLRRTVIGRGARITYHSTVLAGSVVSDDAMLATHALLR
GDIPPHGIAMGVPAKVTRYKRREPWAYSVDSRTYPHDPGRKANPAFPDPTPNQTRKPTLEETGGS

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.18 [C]

Molecular weight: Translated: 33948; Mature: 33817

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGATRATVAGVTWLKPVSINADAQGAYHEFLRDLEARLLDPQTDRYALAREVLAQAMY
CCCCCCHHEECCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GREYGQLLADAPLAALNLDAHNVTFEAEYYMATDPEKFAPVKPLLWLWKNLDLTPIGQNP
HHHHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCHHHCCHHHHHHHHHCCCCEECCCCC
VLGIPIRRVLAERIFKRVGRNFKCWQNVEFSVGYNMEVGNDVVVHRYVLLDDIGGIELQD
EECCCHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCEEEEEEEEEECCCCEEECC
NASVSDYVNIYSHTHSVLDGPDVTLRRTVIGRGARITYHSTVLAGSVVSDDAMLATHALL
CCCHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCEEEEEHHHEECCHHCCCHHHHHHHHH
RGDIPPHGIAMGVPAKVTRYKRREPWAYSVDSRTYPHDPGRKANPAFPDPTPNQTRKPTL
HCCCCCCCEEECCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EETGGS
HCCCCC
>Mature Secondary Structure 
ATGATRATVAGVTWLKPVSINADAQGAYHEFLRDLEARLLDPQTDRYALAREVLAQAMY
CCCCCHHEECCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GREYGQLLADAPLAALNLDAHNVTFEAEYYMATDPEKFAPVKPLLWLWKNLDLTPIGQNP
HHHHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCHHHCCHHHHHHHHHCCCCEECCCCC
VLGIPIRRVLAERIFKRVGRNFKCWQNVEFSVGYNMEVGNDVVVHRYVLLDDIGGIELQD
EECCCHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCEEEEEEEEEECCCCEEECC
NASVSDYVNIYSHTHSVLDGPDVTLRRTVIGRGARITYHSTVLAGSVVSDDAMLATHALL
CCCHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCEEEEEHHHEECCHHCCCHHHHHHHHH
RGDIPPHGIAMGVPAKVTRYKRREPWAYSVDSRTYPHDPGRKANPAFPDPTPNQTRKPTL
HCCCCCCCEEECCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EETGGS
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: MgSO4; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 1500 {isopropyl} 1200 {isopropyl} 770 {isopropyl} 360 {isopropyl} 0.18 {acetyl-CoA}} 0.049 {acetyl-CoA}} 0.045 {acetyl-CoA}} 0.04 {acetyl-CoA}} [C]

Substrates: Acetyl-CoA; a beta-D-galactoside [C]

Specific reaction: Acetyl-CoA + a beta-D-galactoside = CoA + aacetyl-beta-D-galactoside [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; Acetyl-CoA; Co2+; CoA; Cu2+; MgSO4; Mn2+; p-Chloromercuribenzoate; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA