Click here to switch to the map view.

The map label for this gene is 94984336

Identifier: 94984336

GI number: 94984336

Start: 214016

End: 215086

Strand: Reverse

Name: 94984336

Synonym: Dgeo_0228

Alternate gene names: NA

Gene position: 215086-214016 (Counterclockwise)

Preceding gene: 94984341

Following gene: 94984334

Centisome position: 8.72

GC content: 66.01

Gene sequence:

>1071_bases
ATGACCGCTCCGCATGACCCGGCCCTGACCTCTCCCCCGCCGCGCACCCGCAAACGCACCTTTGGCGTGTACATCGGCCG
TTTCGAGCCGCCACACCAGGCCCACCTGTTGGTGATGCTTGAAGCGCTGCAATGGGTCCAAAAGCTGATTGTGGTGATCG
GCAGCGCGCGGGCCGCCCGCAACACCAAGAATCCTTTCACGGCCGAAGAACGGCAGGAGATGATCACGGCGATGCTGCGA
GAAGCGGGCGTGGCAAAAAGCCGCCTGCTCTTCGTGCAGGTGCGCGATTCCTTCTACAACGAGGGGCTGTGGCTCTCAGA
GGTGCAGCGCGGTGTGGCCGAACACACCCGCGGCAGCAGCGACGTGGCCCTGATCGGACACTTCAAGGACGAGAGCAGCT
ATTACCTGCGTTCCTTTCCCGCCTGGGAGTTCCTGCCCACCCACGTGGTGAGTCCTCTGAATGCCACGGACGTGCGAAAA
GCCTTGTTCGAGGACCGCTTGGACGAGGTGCGCAGCATGGTGCCGCCCACCGTCCACGCCTTTCTCAGCGCTTTTCGGCA
GACGCCGGCGTACGCTGAACTCCGCAGCGAGTACGACGACCTGCGCGAGTCCCGCGCGGCGTGGCTTGGCGCACCCTTTC
CCCCGGTCTTCGTGACGGCCGACGCGGTGGTGACGCGCAGTGGACACGTTCTGGTCGTGCGGCGGGCCGGATTCCCAGGG
CGCGGGCGACTCGCCATGCCGGGCGGCTTTCTGAGGCCAGACGAGACCCTGCTCGCCTGTGCCGTCCGCCAGGTCCACAG
CGAAACCGGGCTGAACGCGGCGGTCAACCTCACCGAGCGGGTGCGTTCCCAGGCGGTCTTTGACTATCCGGGCCGCAGCC
AGCGCGGGCGAACCGTGACGCACGCCTTTCACTTCGACCTCGGCCTCGGACAGCTCCCAGTGCTGCAGGCCGCTGCGGGA
GCCGCCGAGGCGTTCTGGATGCCGTTCTCGGAAGCCCTCGCGGAGCCGGAACTGTTTTTCGAGGACCACCACGCGATCAT
CGAGTCCTTTCTGATGCGCGGGAAACTGTAG

Upstream 100 bases:

>100_bases
GAACCACAGCCGGAATCCTGGGGGTCAGCCCCTGCTGCCCCGCTGAGCGGCCAGCCGCTTCGCTCATCCTTCACATCTGC
CCAAGCGCTCACGGTGAGGC

Downstream 100 bases:

>100_bases
GCGGGCACCCGCCCCGTTGGCCCTCAGGACTCGGCGCCCACGCTCAGCGCCCGCACCACCCGCACACCGTTGCGCGCCAA
CTGGTGCAGGAAGAGGGCGT

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTAPHDPALTSPPPRTRKRTFGVYIGRFEPPHQAHLLVMLEALQWVQKLIVVIGSARAARNTKNPFTAEERQEMITAMLR
EAGVAKSRLLFVQVRDSFYNEGLWLSEVQRGVAEHTRGSSDVALIGHFKDESSYYLRSFPAWEFLPTHVVSPLNATDVRK
ALFEDRLDEVRSMVPPTVHAFLSAFRQTPAYAELRSEYDDLRESRAAWLGAPFPPVFVTADAVVTRSGHVLVVRRAGFPG
RGRLAMPGGFLRPDETLLACAVRQVHSETGLNAAVNLTERVRSQAVFDYPGRSQRGRTVTHAFHFDLGLGQLPVLQAAAG
AAEAFWMPFSEALAEPELFFEDHHAIIESFLMRGKL

Sequences:

>Translated_356_residues
MTAPHDPALTSPPPRTRKRTFGVYIGRFEPPHQAHLLVMLEALQWVQKLIVVIGSARAARNTKNPFTAEERQEMITAMLR
EAGVAKSRLLFVQVRDSFYNEGLWLSEVQRGVAEHTRGSSDVALIGHFKDESSYYLRSFPAWEFLPTHVVSPLNATDVRK
ALFEDRLDEVRSMVPPTVHAFLSAFRQTPAYAELRSEYDDLRESRAAWLGAPFPPVFVTADAVVTRSGHVLVVRRAGFPG
RGRLAMPGGFLRPDETLLACAVRQVHSETGLNAAVNLTERVRSQAVFDYPGRSQRGRTVTHAFHFDLGLGQLPVLQAAAG
AAEAFWMPFSEALAEPELFFEDHHAIIESFLMRGKL
>Mature_355_residues
TAPHDPALTSPPPRTRKRTFGVYIGRFEPPHQAHLLVMLEALQWVQKLIVVIGSARAARNTKNPFTAEERQEMITAMLRE
AGVAKSRLLFVQVRDSFYNEGLWLSEVQRGVAEHTRGSSDVALIGHFKDESSYYLRSFPAWEFLPTHVVSPLNATDVRKA
LFEDRLDEVRSMVPPTVHAFLSAFRQTPAYAELRSEYDDLRESRAAWLGAPFPPVFVTADAVVTRSGHVLVVRRAGFPGR
GRLAMPGGFLRPDETLLACAVRQVHSETGLNAAVNLTERVRSQAVFDYPGRSQRGRTVTHAFHFDLGLGQLPVLQAAAGA
AEAFWMPFSEALAEPELFFEDHHAIIESFLMRGKL

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1056

COG function: function code H; Nicotinamide mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 39785; Mature: 39654

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPHDPALTSPPPRTRKRTFGVYIGRFEPPHQAHLLVMLEALQWVQKLIVVIGSARAAR
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
NTKNPFTAEERQEMITAMLREAGVAKSRLLFVQVRDSFYNEGLWLSEVQRGVAEHTRGSS
CCCCCCCHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCC
DVALIGHFKDESSYYLRSFPAWEFLPTHVVSPLNATDVRKALFEDRLDEVRSMVPPTVHA
CEEEEEEECCCCCHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
FLSAFRQTPAYAELRSEYDDLRESRAAWLGAPFPPVFVTADAVVTRSGHVLVVRRAGFPG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCEEEEEECCCCC
RGRLAMPGGFLRPDETLLACAVRQVHSETGLNAAVNLTERVRSQAVFDYPGRSQRGRTVT
CCCEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCCCCEEE
HAFHFDLGLGQLPVLQAAAGAAEAFWMPFSEALAEPELFFEDHHAIIESFLMRGKL
EEEEECCCCCCCHHHHHHCCCHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAPHDPALTSPPPRTRKRTFGVYIGRFEPPHQAHLLVMLEALQWVQKLIVVIGSARAAR
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
NTKNPFTAEERQEMITAMLREAGVAKSRLLFVQVRDSFYNEGLWLSEVQRGVAEHTRGSS
CCCCCCCHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCC
DVALIGHFKDESSYYLRSFPAWEFLPTHVVSPLNATDVRKALFEDRLDEVRSMVPPTVHA
CEEEEEEECCCCCHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
FLSAFRQTPAYAELRSEYDDLRESRAAWLGAPFPPVFVTADAVVTRSGHVLVVRRAGFPG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCEEEEEECCCCC
RGRLAMPGGFLRPDETLLACAVRQVHSETGLNAAVNLTERVRSQAVFDYPGRSQRGRTVT
CCCEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCCCCEEE
HAFHFDLGLGQLPVLQAAAGAAEAFWMPFSEALAEPELFFEDHHAIIESFLMRGKL
EEEEECCCCCCCHHHHHHCCCHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]