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The map label for this gene is czcD [H]

Identifier: 94984323

GI number: 94984323

Start: 199697

End: 200596

Strand: Reverse

Name: czcD [H]

Synonym: Dgeo_0215

Alternate gene names: 94984323

Gene position: 200596-199697 (Counterclockwise)

Preceding gene: 94984324

Following gene: 94984321

Centisome position: 8.13

GC content: 70.22

Gene sequence:

>900_bases
GTGAGCGAACACAGCCACGGGGGGCATCGCCACGGCCGGGACGCGAGCGCCCGCCAGCTTCGCCTGGCGCTGGCGCTGAC
CGGGGCGTTTCTCGTCGTGGAGGTGATCTACGGCTTCCTGTCGGGCAGCCTGGCGCTGCTCTCGGACGCCGGGCACATGC
TCACCGACGTGGCAGCGCTGGCCCTCTCGCTCCTCGCCCTCCGCCTGGGCCGGCGCCCCGCCGACCGCCGGCGCACCTTC
GGCTACCGCCGCAGCGAGATTCTGGCGGCGGCTCTGAACGCCGGGGCGCTGTTTGCCATCGGCATTTCCATCCTGGTGGA
GGCCTATGGGCGATTGCGCGAGCCGGTGGCGGTCCAGACCACACCGATGCTGGTCGTGGCGCTGCTAGGGTTGATCGTGA
ACCTGCTCAGTGCGCGCATCCTGGCCGGGGGCGCGGAGGACAGCCTGAACGTACGATCGGCGTATCTGGAGGTGTTGGGC
GACCTGCTGGGATCCGTGGCGGTGATCATCGGAGCGTTGGTGATTCGCCTCACGGGCCTGACCTGGGTGGACCCGGTGCT
GGGCGCGGGCATCGGCCTGTGGGTGTTGCCGCGCGCCTGGTCACTGCTGCGTTCGAGCGTGAACGTCCTGCTCGAAGGGG
TACCCGAGGGCCTCGACCTCGACGCCCTGCGTGCGGACCTGCGTGCTCTGCCCGGCGTGCAGGAGGTCCACGACCTGCAT
GTCTGGAGCGTGACGAGCGGCGAACACCATCTCACCGCCCACCTCGTCAGCGCCGAGACTCCGGCTGACCTGCTGCCCCA
GGTCCACGAGGTCGCGGAGCGCTACGGCATCGAGCACGTGACCGTGCAGGTGGAGCCGGAGGGCGTGCACGCAGGACACA
CCGAGCACCTGCACCCCTGA

Upstream 100 bases:

>100_bases
GCGAGGAGGCCGCCCACGCCGCCGCCCGCAGGCAGGTGCGCGAACTCTTCCCGGCCCTGGCCAAGCAACTGTCCGGGCAG
GACGGGGAGCAGGCCGGGGC

Downstream 100 bases:

>100_bases
ACACCGGCACCCCTGAGGAGACCTACGCTTCCCCCTCCAAGCGCGCGAGATCCTCTGGCGTATCCACATCGGTCAGCAGG
TCAGCCGGCAAGCGCAGTGT

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSEHSHGGHRHGRDASARQLRLALALTGAFLVVEVIYGFLSGSLALLSDAGHMLTDVAALALSLLALRLGRRPADRRRTF
GYRRSEILAAALNAGALFAIGISILVEAYGRLREPVAVQTTPMLVVALLGLIVNLLSARILAGGAEDSLNVRSAYLEVLG
DLLGSVAVIIGALVIRLTGLTWVDPVLGAGIGLWVLPRAWSLLRSSVNVLLEGVPEGLDLDALRADLRALPGVQEVHDLH
VWSVTSGEHHLTAHLVSAETPADLLPQVHEVAERYGIEHVTVQVEPEGVHAGHTEHLHP

Sequences:

>Translated_299_residues
MSEHSHGGHRHGRDASARQLRLALALTGAFLVVEVIYGFLSGSLALLSDAGHMLTDVAALALSLLALRLGRRPADRRRTF
GYRRSEILAAALNAGALFAIGISILVEAYGRLREPVAVQTTPMLVVALLGLIVNLLSARILAGGAEDSLNVRSAYLEVLG
DLLGSVAVIIGALVIRLTGLTWVDPVLGAGIGLWVLPRAWSLLRSSVNVLLEGVPEGLDLDALRADLRALPGVQEVHDLH
VWSVTSGEHHLTAHLVSAETPADLLPQVHEVAERYGIEHVTVQVEPEGVHAGHTEHLHP
>Mature_298_residues
SEHSHGGHRHGRDASARQLRLALALTGAFLVVEVIYGFLSGSLALLSDAGHMLTDVAALALSLLALRLGRRPADRRRTFG
YRRSEILAAALNAGALFAIGISILVEAYGRLREPVAVQTTPMLVVALLGLIVNLLSARILAGGAEDSLNVRSAYLEVLGD
LLGSVAVIIGALVIRLTGLTWVDPVLGAGIGLWVLPRAWSLLRSSVNVLLEGVPEGLDLDALRADLRALPGVQEVHDLHV
WSVTSGEHHLTAHLVSAETPADLLPQVHEVAERYGIEHVTVQVEPEGVHAGHTEHLHP

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=297, Percent_Identity=28.6195286195286, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI21361112, Length=297, Percent_Identity=32.6599326599327, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI21359890, Length=305, Percent_Identity=30.1639344262295, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI64762489, Length=271, Percent_Identity=32.1033210332103, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI289803013, Length=273, Percent_Identity=31.8681318681319, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI289803009, Length=273, Percent_Identity=31.8681318681319, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI289803007, Length=273, Percent_Identity=31.8681318681319, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI289803003, Length=273, Percent_Identity=31.8681318681319, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI20070323, Length=321, Percent_Identity=27.4143302180685, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI52351208, Length=150, Percent_Identity=31.3333333333333, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI14210520, Length=144, Percent_Identity=29.8611111111111, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI52352803, Length=121, Percent_Identity=43.801652892562, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI222080086, Length=123, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40255009, Length=123, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786966, Length=284, Percent_Identity=48.5915492957746, Blast_Score=188, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17555794, Length=310, Percent_Identity=33.8709677419355, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17555796, Length=285, Percent_Identity=34.7368421052632, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI193210990, Length=314, Percent_Identity=32.1656050955414, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32564488, Length=301, Percent_Identity=32.890365448505, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17550442, Length=122, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17550440, Length=122, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320411, Length=190, Percent_Identity=36.3157894736842, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323899, Length=143, Percent_Identity=37.7622377622378, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324892, Length=122, Percent_Identity=37.7049180327869, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24583858, Length=330, Percent_Identity=26.969696969697, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24656728, Length=124, Percent_Identity=38.7096774193548, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656724, Length=124, Percent_Identity=38.7096774193548, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656720, Length=124, Percent_Identity=38.7096774193548, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656715, Length=124, Percent_Identity=38.7096774193548, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357035, Length=124, Percent_Identity=38.7096774193548, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24585900, Length=148, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585898, Length=148, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585896, Length=148, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921672, Length=148, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584409, Length=136, Percent_Identity=33.8235294117647, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28574430, Length=136, Percent_Identity=33.8235294117647, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24645863, Length=123, Percent_Identity=39.0243902439024, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 31855; Mature: 31724

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHSHGGHRHGRDASARQLRLALALTGAFLVVEVIYGFLSGSLALLSDAGHMLTDVAAL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHH
ALSLLALRLGRRPADRRRTFGYRRSEILAAALNAGALFAIGISILVEAYGRLREPVAVQT
HHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECH
TPMLVVALLGLIVNLLSARILAGGAEDSLNVRSAYLEVLGDLLGSVAVIIGALVIRLTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TWVDPVLGAGIGLWVLPRAWSLLRSSVNVLLEGVPEGLDLDALRADLRALPGVQEVHDLH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHEE
VWSVTSGEHHLTAHLVSAETPADLLPQVHEVAERYGIEHVTVQVEPEGVHAGHTEHLHP
EEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEHSHGGHRHGRDASARQLRLALALTGAFLVVEVIYGFLSGSLALLSDAGHMLTDVAAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHH
ALSLLALRLGRRPADRRRTFGYRRSEILAAALNAGALFAIGISILVEAYGRLREPVAVQT
HHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECH
TPMLVVALLGLIVNLLSARILAGGAEDSLNVRSAYLEVLGDLLGSVAVIIGALVIRLTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TWVDPVLGAGIGLWVLPRAWSLLRSSVNVLLEGVPEGLDLDALRADLRALPGVQEVHDLH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHEE
VWSVTSGEHHLTAHLVSAETPADLLPQVHEVAERYGIEHVTVQVEPEGVHAGHTEHLHP
EEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]