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The map label for this gene is nudF [H]

Identifier: 94984183

GI number: 94984183

Start: 71427

End: 72053

Strand: Reverse

Name: nudF [H]

Synonym: Dgeo_0075

Alternate gene names: 94984183

Gene position: 72053-71427 (Counterclockwise)

Preceding gene: 94984184

Following gene: 94984182

Centisome position: 2.92

GC content: 69.7

Gene sequence:

>627_bases
ATGGCCGAGGAGCGGACAGAGGGAACCGGAGCCGTCTCCCACCGAGCGCATCCGAACTGGGCAGGGTTGATCCCCGACGC
GGTGCAGCCCTGGGAAACACTGTCGTCGCGGGTGCTGGTGGAGGGCTTCCGAGTGGTGCTCGAAGACCGGGCGCGAACGG
CAACGGGCGCAGAGGTGGTGTACCAGTACCGCCCCCGTGGGCCGAGGGCAGTGTTCATGCTGCCGGTGACCCCAGCGGGT
GAGGCGGTGCTGATTCGCCAGTACCGCTATCCCCTGCGGGCGACCATCTGGGAGGTTGTGGCGGGCGGTGTGGAGCGCGG
GGAGGACCTGCTGGCCGCCGCCGCTCGTGAGCTGGCCGAGGAGGTGGGGGGCGTGGCGACGGAGTGGATTCCGCTCCCGG
GCTTCTATCCGCAGCCCAGCATCAGCGGCGTGGTGTTTTACCCGCTGCTCGCGCTCAACGTGACGCTGGGCGAAACGGCC
CAAGAAGAGAGCGAGGTGATCGAGCGGGTCACCCTCCCCCTCGCGGAAGCCTACCGGATGCTGGAGGCGGGCGAGATTCA
GGACGGCCCCAGCAGCCTGACCCTGTGGCACGCGCGGCGGCATCTGGTGGAGCGCGGCCTGCTGTGA

Upstream 100 bases:

>100_bases
GCCTGCTCCTCGCCCACTCGGATCCCGATCCGCAAGCTGCTGGGCGAGCGGGTGCAGATCGCCTGCAAGGTGGCCCCTCC
CGCTGGGGTAGCCTGCGCAC

Downstream 100 bases:

>100_bases
ACGACCTGCCCGCCCCCTTCACTACCCTCGCCGCGCCGCACCGCCAGGACGCGGTGATCGAGAACAGCGAGTTCCTGGCC
TTTGCCGAGCGGGCCGACAC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MAEERTEGTGAVSHRAHPNWAGLIPDAVQPWETLSSRVLVEGFRVVLEDRARTATGAEVVYQYRPRGPRAVFMLPVTPAG
EAVLIRQYRYPLRATIWEVVAGGVERGEDLLAAAARELAEEVGGVATEWIPLPGFYPQPSISGVVFYPLLALNVTLGETA
QEESEVIERVTLPLAEAYRMLEAGEIQDGPSSLTLWHARRHLVERGLL

Sequences:

>Translated_208_residues
MAEERTEGTGAVSHRAHPNWAGLIPDAVQPWETLSSRVLVEGFRVVLEDRARTATGAEVVYQYRPRGPRAVFMLPVTPAG
EAVLIRQYRYPLRATIWEVVAGGVERGEDLLAAAARELAEEVGGVATEWIPLPGFYPQPSISGVVFYPLLALNVTLGETA
QEESEVIERVTLPLAEAYRMLEAGEIQDGPSSLTLWHARRHLVERGLL
>Mature_207_residues
AEERTEGTGAVSHRAHPNWAGLIPDAVQPWETLSSRVLVEGFRVVLEDRARTATGAEVVYQYRPRGPRAVFMLPVTPAGE
AVLIRQYRYPLRATIWEVVAGGVERGEDLLAAAARELAEEVGGVATEWIPLPGFYPQPSISGVVFYPLLALNVTLGETAQ
EESEVIERVTLPLAEAYRMLEAGEIQDGPSSLTLWHARRHLVERGLL

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 22892; Mature: 22761

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEERTEGTGAVSHRAHPNWAGLIPDAVQPWETLSSRVLVEGFRVVLEDRARTATGAEVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEE
YQYRPRGPRAVFMLPVTPAGEAVLIRQYRYPLRATIWEVVAGGVERGEDLLAAAARELAE
EEECCCCCCEEEEEECCCCCCEEEEHHHCCCHHHHHHHHHHCCHHCCHHHHHHHHHHHHH
EVGGVATEWIPLPGFYPQPSISGVVFYPLLALNVTLGETAQEESEVIERVTLPLAEAYRM
HHCCCEEECEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEAGEIQDGPSSLTLWHARRHLVERGLL
HHCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEERTEGTGAVSHRAHPNWAGLIPDAVQPWETLSSRVLVEGFRVVLEDRARTATGAEVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEE
YQYRPRGPRAVFMLPVTPAGEAVLIRQYRYPLRATIWEVVAGGVERGEDLLAAAARELAE
EEECCCCCCEEEEEECCCCCCEEEEHHHCCCHHHHHHHHHHCCHHCCHHHHHHHHHHHHH
EVGGVATEWIPLPGFYPQPSISGVVFYPLLALNVTLGETAQEESEVIERVTLPLAEAYRM
HHCCCEEECEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEAGEIQDGPSSLTLWHARRHLVERGLL
HHCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]