| Definition | Deinococcus geothermalis DSM 11300, complete genome. |
|---|---|
| Accession | NC_008025 |
| Length | 2,467,205 |
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The map label for this gene is ppiB [H]
Identifier: 94984178
GI number: 94984178
Start: 67615
End: 68199
Strand: Reverse
Name: ppiB [H]
Synonym: Dgeo_0070
Alternate gene names: 94984178
Gene position: 68199-67615 (Counterclockwise)
Preceding gene: 94984179
Following gene: 94984177
Centisome position: 2.76
GC content: 66.5
Gene sequence:
>585_bases ATGACCAGCCAGGACACCTACCAGGCCGACGGCTTCACGCCCACCCCCGAACTCGCGCGCGAGCGCCAGACGCGCTTTTC CGCAGCTCCCGAACTCGGCGAGGGCATCGAACCCGGCAAGCAGTACCGCGCAGTCCTGGAAACGAGCAAGGGCCGCATCG TGCTCGACCTGTTTGCCGATGAGGCACCCGTCACCGTGAACTCGTTTGCGTATCTGCTGCGCCACCACTACTACGACGGC ATCAAGTTCCACCGCGTGATCGACGGCTTCATGGCCCAGGGCGGCGACCCCACCGGCACCGGTGCGGGCGGTCCGGGCTA TGACTTCGAGGACGAATTCAGCCCTGACCTGCGGCACGACCGCAAGGGTGTGCTGAGCATGGCCAACCGCGGCCCCAACA CCAACGGCTCGCAGTTTTTCATCACCTTTGGCCCGACGCCGCACCTTGACGGGCGGCACACCGTCTTTGGGCGTGTGGTG GAGGGCCTGGACGTGCTGGACCGCCTGACGCGCATCCAGCCGGGGATGCCCGGCACGCCGGACGTGATCGAGCGGGCGTA CCTGGTGGAAAAAACGGCAGGCTGA
Upstream 100 bases:
>100_bases ATGGGTGGTGGGCGAGCGTTCAGCGGCTGAGGCCAAGGCTTAAGCCTTCCCGTCGGCCGGCAGACCGCTCGCCCACCGGC CCGACCGGTACAATGCCGCC
Downstream 100 bases:
>100_bases GGGCGGGCGGGCCGCGGCGGCGAGCGGAAGCGGCGCTTTCTGCCCTCTGTGGGCGTGCGGTGAGAGGGGCCGCGCTACAC TCGTCCCATGGACAACCGCA
Product: peptidylprolyl isomerase
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 194; Mature: 193
Protein sequence:
>194_residues MTSQDTYQADGFTPTPELARERQTRFSAAPELGEGIEPGKQYRAVLETSKGRIVLDLFADEAPVTVNSFAYLLRHHYYDG IKFHRVIDGFMAQGGDPTGTGAGGPGYDFEDEFSPDLRHDRKGVLSMANRGPNTNGSQFFITFGPTPHLDGRHTVFGRVV EGLDVLDRLTRIQPGMPGTPDVIERAYLVEKTAG
Sequences:
>Translated_194_residues MTSQDTYQADGFTPTPELARERQTRFSAAPELGEGIEPGKQYRAVLETSKGRIVLDLFADEAPVTVNSFAYLLRHHYYDG IKFHRVIDGFMAQGGDPTGTGAGGPGYDFEDEFSPDLRHDRKGVLSMANRGPNTNGSQFFITFGPTPHLDGRHTVFGRVV EGLDVLDRLTRIQPGMPGTPDVIERAYLVEKTAG >Mature_193_residues TSQDTYQADGFTPTPELARERQTRFSAAPELGEGIEPGKQYRAVLETSKGRIVLDLFADEAPVTVNSFAYLLRHHYYDGI KFHRVIDGFMAQGGDPTGTGAGGPGYDFEDEFSPDLRHDRKGVLSMANRGPNTNGSQFFITFGPTPHLDGRHTVFGRVVE GLDVLDRLTRIQPGMPGTPDVIERAYLVEKTAG
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=131, Percent_Identity=55.7251908396947, Blast_Score=152, Evalue=1e-37, Organism=Homo sapiens, GI24308049, Length=133, Percent_Identity=56.390977443609, Blast_Score=150, Evalue=6e-37, Organism=Homo sapiens, GI19557636, Length=132, Percent_Identity=53.030303030303, Blast_Score=147, Evalue=5e-36, Organism=Homo sapiens, GI64276486, Length=127, Percent_Identity=46.4566929133858, Blast_Score=122, Evalue=1e-28, Organism=Homo sapiens, GI22547212, Length=131, Percent_Identity=53.4351145038168, Blast_Score=121, Evalue=4e-28, Organism=Homo sapiens, GI7657473, Length=131, Percent_Identity=53.4351145038168, Blast_Score=121, Evalue=4e-28, Organism=Homo sapiens, GI22547215, Length=131, Percent_Identity=53.4351145038168, Blast_Score=120, Evalue=5e-28, Organism=Homo sapiens, GI4826932, Length=138, Percent_Identity=48.5507246376812, Blast_Score=117, Evalue=4e-27, Organism=Homo sapiens, GI10863927, Length=129, Percent_Identity=48.8372093023256, Blast_Score=111, Evalue=5e-25, Organism=Homo sapiens, GI45439316, Length=128, Percent_Identity=49.21875, Blast_Score=108, Evalue=3e-24, Organism=Homo sapiens, GI303305009, Length=126, Percent_Identity=50, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI5174637, Length=137, Percent_Identity=48.9051094890511, Blast_Score=107, Evalue=6e-24, Organism=Homo sapiens, GI6631100, Length=146, Percent_Identity=44.5205479452055, Blast_Score=106, Evalue=1e-23, Organism=Homo sapiens, GI20911035, Length=138, Percent_Identity=40.5797101449275, Blast_Score=106, Evalue=1e-23, Organism=Homo sapiens, GI42560244, Length=138, Percent_Identity=45.6521739130435, Blast_Score=105, Evalue=2e-23, Organism=Homo sapiens, GI5031987, Length=126, Percent_Identity=50.7936507936508, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI256017253, Length=124, Percent_Identity=47.5806451612903, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI221139811, Length=124, Percent_Identity=47.5806451612903, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI256017251, Length=124, Percent_Identity=47.5806451612903, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI4505991, Length=126, Percent_Identity=48.4126984126984, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI310127646, Length=135, Percent_Identity=41.4814814814815, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI310114371, Length=135, Percent_Identity=41.4814814814815, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI310119221, Length=135, Percent_Identity=41.4814814814815, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI5454154, Length=154, Percent_Identity=41.5584415584416, Blast_Score=100, Evalue=7e-22, Organism=Homo sapiens, GI178057341, Length=126, Percent_Identity=46.031746031746, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4758950, Length=126, Percent_Identity=47.6190476190476, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI310129267, Length=126, Percent_Identity=45.2380952380952, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI310120620, Length=126, Percent_Identity=45.2380952380952, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI209417936, Length=126, Percent_Identity=46.031746031746, Blast_Score=97, Evalue=8e-21, Organism=Homo sapiens, GI30102944, Length=126, Percent_Identity=46.031746031746, Blast_Score=97, Evalue=8e-21, Organism=Homo sapiens, GI219842199, Length=126, Percent_Identity=46.031746031746, Blast_Score=97, Evalue=8e-21, Organism=Homo sapiens, GI14277126, Length=76, Percent_Identity=59.2105263157895, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI310110104, Length=125, Percent_Identity=43.2, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI169163387, Length=126, Percent_Identity=44.4444444444444, Blast_Score=95, Evalue=4e-20, Organism=Homo sapiens, GI169164185, Length=126, Percent_Identity=44.4444444444444, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI169163623, Length=126, Percent_Identity=44.4444444444444, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI150418007, Length=174, Percent_Identity=39.0804597701149, Blast_Score=94, Evalue=8e-20, Organism=Homo sapiens, GI169214050, Length=175, Percent_Identity=34.8571428571429, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI27735045, Length=138, Percent_Identity=39.8550724637681, Blast_Score=92, Evalue=2e-19, Organism=Homo sapiens, GI310132444, Length=129, Percent_Identity=43.4108527131783, Blast_Score=91, Evalue=5e-19, Organism=Homo sapiens, GI310113152, Length=129, Percent_Identity=43.4108527131783, Blast_Score=91, Evalue=5e-19, Organism=Homo sapiens, GI239751853, Length=130, Percent_Identity=40, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI113428306, Length=130, Percent_Identity=40, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI310114540, Length=123, Percent_Identity=39.8373983739837, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI310127745, Length=123, Percent_Identity=39.8373983739837, Blast_Score=83, Evalue=1e-16, Organism=Homo sapiens, GI310119290, Length=123, Percent_Identity=39.8373983739837, Blast_Score=83, Evalue=1e-16, Organism=Homo sapiens, GI289803023, Length=164, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=5e-16, Organism=Escherichia coli, GI1789763, Length=159, Percent_Identity=34.5911949685535, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1786736, Length=157, Percent_Identity=33.1210191082803, Blast_Score=73, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17539496, Length=156, Percent_Identity=48.0769230769231, Blast_Score=150, Evalue=4e-37, Organism=Caenorhabditis elegans, GI17506311, Length=143, Percent_Identity=51.0489510489511, Blast_Score=139, Evalue=6e-34, Organism=Caenorhabditis elegans, GI17532641, Length=148, Percent_Identity=48.6486486486487, Blast_Score=134, Evalue=4e-32, Organism=Caenorhabditis elegans, GI71980594, Length=131, Percent_Identity=46.5648854961832, Blast_Score=129, Evalue=9e-31, Organism=Caenorhabditis elegans, GI71980590, Length=133, Percent_Identity=45.8646616541353, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI71997782, Length=129, Percent_Identity=44.1860465116279, Blast_Score=116, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17551282, Length=143, Percent_Identity=46.8531468531469, Blast_Score=116, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17551284, Length=143, Percent_Identity=46.8531468531469, Blast_Score=115, Evalue=1e-26, Organism=Caenorhabditis elegans, GI32563659, Length=138, Percent_Identity=42.0289855072464, Blast_Score=111, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17506307, Length=145, Percent_Identity=48.9655172413793, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17566266, Length=133, Percent_Identity=48.1203007518797, Blast_Score=107, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559074, Length=135, Percent_Identity=48.1481481481481, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17552780, Length=126, Percent_Identity=50.7936507936508, Blast_Score=106, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17552782, Length=149, Percent_Identity=44.2953020134228, Blast_Score=105, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17539498, Length=141, Percent_Identity=47.5177304964539, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17565860, Length=143, Percent_Identity=43.3566433566434, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17552784, Length=145, Percent_Identity=43.448275862069, Blast_Score=104, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17532643, Length=144, Percent_Identity=40.9722222222222, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI115533296, Length=132, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=5e-15, Organism=Caenorhabditis elegans, GI32563661, Length=69, Percent_Identity=49.2753623188406, Blast_Score=68, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6320359, Length=151, Percent_Identity=46.3576158940397, Blast_Score=111, Evalue=8e-26, Organism=Saccharomyces cerevisiae, GI6320510, Length=149, Percent_Identity=45.6375838926174, Blast_Score=110, Evalue=2e-25, Organism=Saccharomyces cerevisiae, GI6323562, Length=152, Percent_Identity=45.3947368421053, Blast_Score=108, Evalue=4e-25, Organism=Saccharomyces cerevisiae, GI6323246, Length=139, Percent_Identity=46.7625899280576, Blast_Score=106, Evalue=3e-24, Organism=Saccharomyces cerevisiae, GI6321848, Length=136, Percent_Identity=48.5294117647059, Blast_Score=104, Evalue=1e-23, Organism=Saccharomyces cerevisiae, GI6322492, Length=186, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=6e-16, Organism=Drosophila melanogaster, GI19922376, Length=143, Percent_Identity=49.6503496503497, Blast_Score=147, Evalue=4e-36, Organism=Drosophila melanogaster, GI17986117, Length=142, Percent_Identity=52.112676056338, Blast_Score=147, Evalue=5e-36, Organism=Drosophila melanogaster, GI19922912, Length=125, Percent_Identity=60, Blast_Score=128, Evalue=3e-30, Organism=Drosophila melanogaster, GI24652460, Length=130, Percent_Identity=45.3846153846154, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI21357249, Length=127, Percent_Identity=44.0944881889764, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI24650807, Length=134, Percent_Identity=48.5074626865672, Blast_Score=113, Evalue=8e-26, Organism=Drosophila melanogaster, GI24664125, Length=126, Percent_Identity=50, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI21357783, Length=126, Percent_Identity=50, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI45549139, Length=126, Percent_Identity=50, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI17647301, Length=142, Percent_Identity=46.4788732394366, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI24586038, Length=151, Percent_Identity=42.3841059602649, Blast_Score=103, Evalue=6e-23, Organism=Drosophila melanogaster, GI20130249, Length=126, Percent_Identity=49.2063492063492, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI21355677, Length=136, Percent_Identity=43.3823529411765, Blast_Score=99, Evalue=1e-21, Organism=Drosophila melanogaster, GI17136360, Length=149, Percent_Identity=38.9261744966443, Blast_Score=96, Evalue=1e-20, Organism=Drosophila melanogaster, GI24661775, Length=152, Percent_Identity=34.2105263157895, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21355237, Length=152, Percent_Identity=34.2105263157895, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24661771, Length=152, Percent_Identity=34.2105263157895, Blast_Score=79, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 21333; Mature: 21202
Theoretical pI: Translated: 5.29; Mature: 5.29
Prosite motif: PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSQDTYQADGFTPTPELARERQTRFSAAPELGEGIEPGKQYRAVLETSKGRIVLDLFAD CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC EAPVTVNSFAYLLRHHYYDGIKFHRVIDGFMAQGGDPTGTGAGGPGYDFEDEFSPDLRHD CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH RKGVLSMANRGPNTNGSQFFITFGPTPHLDGRHTVFGRVVEGLDVLDRLTRIQPGMPGTP HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH DVIERAYLVEKTAG HHHHHHHHHHCCCC >Mature Secondary Structure TSQDTYQADGFTPTPELARERQTRFSAAPELGEGIEPGKQYRAVLETSKGRIVLDLFAD CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC EAPVTVNSFAYLLRHHYYDGIKFHRVIDGFMAQGGDPTGTGAGGPGYDFEDEFSPDLRHD CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH RKGVLSMANRGPNTNGSQFFITFGPTPHLDGRHTVFGRVVEGLDVLDRLTRIQPGMPGTP HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH DVIERAYLVEKTAG HHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9317025; 9665876 [H]