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The map label for this gene is yitU [H]

Identifier: 94994933

GI number: 94994933

Start: 1470746

End: 1471558

Strand: Direct

Name: yitU [H]

Synonym: MGAS10750_Spy1537

Alternate gene names: 94994933

Gene position: 1470746-1471558 (Clockwise)

Preceding gene: 94994928

Following gene: 94994934

Centisome position: 75.92

GC content: 39.98

Gene sequence:

>813_bases
ATGACTAAAAAATTGATTGCCATTGATTTGGATGGAACCTTATTACATCATGACAACACCATCTCTACCTATACTCAAAA
AACCATCAAAGCTGTCCAAGACAAGGGCCACCACGTCATTATTTCAACAGGCCGTCCTTACCGCATGGCACTGGACTACT
ATCTGCAGCTCAATTTAAAGACCCCAATCATTACTTTTAATGGGGCCTTGACCCACATGCCTGAACAAAAATGGGCCTAT
GAACATAATGTCACTTTGGACAAAGGCTACCTACTAAGGTTACTACAATATCAGGATGATTTCCAGATGGATTTTATTGC
CAGTGAGTATCGAAAAAATGTCTACATTACCATGACCAATCCAGAAAGTATCGACCCGCAACTCTTTGGTGTTGATGAAA
TTACTCAGGACATGGCATTAGAGATTACCAAAATCACTCGAAATCCAAACGCCTTATTGATGCAAACGCGCCACGAAGAC
AAGTATGCCTTAGCTAAAAACATGCGTGCTTTCTTCAAAGATGAAATTGAAATTGATTCTTGGGGAGGCCCTCTCAACAT
TCTTGAAATTTCGTCTAAGAATGTCAATAAAGCTTACGCTCTGAACTATCTCCTTGGAATTTACAATATGGATAAAAAGG
ATTTAATCGCCTTTGGTGATGAACACAATGACACTGAGATGCTAGCTTTTGCTGGAACTGGTTATGCCATGAAAAATGCT
AGCCCTGTGCTACTGCCTTATGCTGATCAGCAGCTTAATTTTTCCAACGAAGAAGACGGTGTTGCCAAAAAATTGGAAGA
ACTTTTCTTGTAG

Upstream 100 bases:

>100_bases
TTATTCATTAAAAAAACAGTTATCCTATCTTTTTTACTAATGAATACACTTAACTTATCTTTTCTCTTTATCTTGGAGCA
AAATTTGCTATAATTTAATT

Downstream 100 bases:

>100_bases
TAGCAAACGAAACCACTATTTTTCAGAAAATGGTGGTTTTTCTTCTGTCCACAGCTATCAAAAAATGAAAATCATTTTAA
TAATTTCAACATTTTTCAGC

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAY
EHNVTLDKGYLLRLLQYQDDFQMDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHED
KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNA
SPVLLPYADQQLNFSNEEDGVAKKLEELFL

Sequences:

>Translated_270_residues
MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAY
EHNVTLDKGYLLRLLQYQDDFQMDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHED
KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNA
SPVLLPYADQQLNFSNEEDGVAKKLEELFL
>Mature_269_residues
TKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYE
HNVTLDKGYLLRLLQYQDDFQMDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHEDK
YALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNAS
PVLLPYADQQLNFSNEEDGVAKKLEELFL

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=296, Percent_Identity=29.3918918918919, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994981, Length=274, Percent_Identity=28.4671532846715, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 31001; Mature: 30870

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMALDYYLQLNLK
CCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEEECC
TPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLQYQDDFQMDFIASEYRKNVYITMTN
CCEEEECCCEECCCCHHCCEECCCEECHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECC
PESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHEDKYALAKNMRAFFKDEIEIDS
CCCCCCEEECHHHHHHHHHEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEC
WGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNA
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEECCCEEECCC
SPVLLPYADQQLNFSNEEDGVAKKLEELFL
CEEEEECCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMALDYYLQLNLK
CCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEEECC
TPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLQYQDDFQMDFIASEYRKNVYITMTN
CCEEEECCCEECCCCHHCCEECCCEECHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECC
PESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHEDKYALAKNMRAFFKDEIEIDS
CCCCCCEEECHHHHHHHHHEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEC
WGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNA
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEECCCEEECCC
SPVLLPYADQQLNFSNEEDGVAKKLEELFL
CEEEEECCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9025291; 9384377 [H]