Click here to switch to the map view.

The map label for this gene is nisX1 [H]

Identifier: 94994631

GI number: 94994631

Start: 1179048

End: 1179473

Strand: Direct

Name: nisX1 [H]

Synonym: MGAS10750_Spy1235

Alternate gene names: 94994631

Gene position: 1179048-1179473 (Clockwise)

Preceding gene: 94994630

Following gene: 94994643

Centisome position: 60.87

GC content: 37.79

Gene sequence:

>426_bases
GTGTCTGTCTTGATAGACGTTTATAGTAGAAAGATTGTTGGTTGGCCAATGGGCCGACGTATGCAAGACAAGTTGGTAAC
AGAAGCTTTCAATCAAGCTTATAATAGAGAAAAGCCTAAAGAAGGGGTAATCGTCCATACAGATCAGGGTTCTCAATATA
CCGGAGCACGATTTCAGGACCTACTTAGACGGAAAAAATGTAAGTCCAGTATGAGTCGAAAAGGTAATCCATACGATAAT
GCACTCATGGAAGCCTTTTATAAAACATTAAAAAGAGAGCTTGTCAATGATGCTCATTTCGCAACTATTGAGCAAGCTCA
GCTTGAGATTTTTAAATATAGTGAGACTTACTATAACCCTAAACGTCTGCATTCAGCTTTAGGATATCTCTCACCTGTAG
AATTTGAAAAAATAGTTACTCATTAG

Upstream 100 bases:

>100_bases
TCGTCCCAATCTTGTTAATCAATGTTTCCAAGCGACTGGTAAGAATAAATTATAGCTAGGAGACTTAACCTACATTCCTA
CACAAGAAGGAATACTTTAT

Downstream 100 bases:

>100_bases
CTTAACTTTATGTCTATTTTTTCTTGACAAGTCCAACCAAATGTTAGATTTTTTGTCCAACTTTTGGGGTGCAGTTCAGT
CATTCGAAGCTTTTTATTAT

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSVLIDVYSRKIVGWPMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGARFQDLLRRKKCKSSMSRKGNPYDN
ALMEAFYKTLKRELVNDAHFATIEQAQLEIFKYSETYYNPKRLHSALGYLSPVEFEKIVTH

Sequences:

>Translated_141_residues
MSVLIDVYSRKIVGWPMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGARFQDLLRRKKCKSSMSRKGNPYDN
ALMEAFYKTLKRELVNDAHFATIEQAQLEIFKYSETYYNPKRLHSALGYLSPVEFEKIVTH
>Mature_140_residues
SVLIDVYSRKIVGWPMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGARFQDLLRRKKCKSSMSRKGNPYDNA
LMEAFYKTLKRELVNDAHFATIEQAQLEIFKYSETYYNPKRLHSALGYLSPVEFEKIVTH

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=95, Percent_Identity=38.9473684210526, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788405, Length=136, Percent_Identity=43.3823529411765, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1787263, Length=136, Percent_Identity=43.3823529411765, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1786753, Length=136, Percent_Identity=43.3823529411765, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1786570, Length=136, Percent_Identity=43.3823529411765, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1786490, Length=136, Percent_Identity=43.3823529411765, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789981, Length=135, Percent_Identity=34.8148148148148, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 16487; Mature: 16356

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIDVYSRKIVGWPMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGARFQD
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHH
LLRRKKCKSSMSRKGNPYDNALMEAFYKTLKRELVNDAHFATIEQAQLEIFKYSETYYNP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
KRLHSALGYLSPVEFEKIVTH
HHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
SVLIDVYSRKIVGWPMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGARFQD
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHH
LLRRKKCKSSMSRKGNPYDNALMEAFYKTLKRELVNDAHFATIEQAQLEIFKYSETYYNP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
KRLHSALGYLSPVEFEKIVTH
HHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]