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The map label for this gene is citE [H]

Identifier: 94994452

GI number: 94994452

Start: 998287

End: 999174

Strand: Direct

Name: citE [H]

Synonym: MGAS10750_Spy1056

Alternate gene names: 94994452

Gene position: 998287-999174 (Clockwise)

Preceding gene: 94994451

Following gene: 94994453

Centisome position: 51.53

GC content: 42.79

Gene sequence:

>888_bases
ATGGAACGTTTAAGAAGAACAATGATGTTTGTGCCAGGTGCCAATGCTGCTATGCTTCGAGATGCTCCTTTGTTTGGTGC
TGATTCCGTCATGTTTGACTTGGAAGATTCTGTTTCACTCAAAGAAAAAGACACTTCTAGAGCTCTCGTCCATTTTGCGC
TAAAAACTTTTGATTATTCGAGCGTTGAAACGGTTGTTCGTGTGAATGGTCTTGATTCTTGTGGGGCTTTAGACATCGAA
GCTGTTGTTTTGGCAGGTGTCAACGTGATTCGTCTTCCAAAAACAGAGACTGCACAAGATATTGTTGATGTGGAGGCTGT
TATTGAACGTGTCGAACGCGAAAACGGCATTGAAGTTGGTCGCACACGCATGATGGCAGCCATTGAATCAGCCGAAGGTG
TTCTAAATGCTCGTGAGATTGCCAAAGCTTCTAAGCGCTTGATTGGTATTGCTCTTGGGGCAGAAGACTATGTCACGAAT
ATGAAAACGCGTCGTTACCCAGATGGTCAAGAATTATTCTTTGCTCGTAGCATGATTTTACATGCTGCTCGTGCTGCTGG
AATTGCTGCCATTGATACTGTTTATTCTGATGTCAATAATACAGAAGGATTCCAAAACGAAGTTCGTATGATCAAACAGT
TAGGATTTGACGGTAAATCGGTCATCAACCCTCGTCAAATTCCTCTGGTCAATGAGATTTATACCCCAACCGAAAAAGAA
ATTGACCATGCCAAACAAGTCATCTGGGCAATTCGTGAAGCTGAAAGCAAAGGCTCTGGCGTTATTTCCTTAAATGGAAA
AATGGTTGATAAACCAATCGTTGAACGTGCAGAACGTGTCATTGCCCTAGCAACAGCAGCAGGTGTTTTATCTGAGGAGG
ACATTTAA

Upstream 100 bases:

>100_bases
TTGATAAAGGCGCTTTAGATTGCACCATTCAAGCGAGAACCATCGCAGCTGTTCATCGCGCAGCTGGTGTTGACCAATAC
GATTGGAAGGAGATTGACTC

Downstream 100 bases:

>100_bases
AGATGGTAACAAATAAACTCGGTAGAGATATTCCTCAACCATACGCCGACCAATACGGTGTCTTTGAAGGAGAACTCGCA
AATATCAAACAGTATGACGA

Product: citrate lyase subunit beta

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIE
AVVLAGVNVIRLPKTETAQDIVDVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTEKE
IDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI

Sequences:

>Translated_295_residues
MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIE
AVVLAGVNVIRLPKTETAQDIVDVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTEKE
IDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
>Mature_295_residues
MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIE
AVVLAGVNVIRLPKTETAQDIVDVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTEKE
IDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=293, Percent_Identity=27.6450511945392, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI87081764, Length=291, Percent_Identity=58.0756013745705, Blast_Score=329, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17557458, Length=295, Percent_Identity=28.8135593220339, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 32340; Mature: 32340

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKDTSRALVHFALKTFDYS
CHHHHHHEEECCCCCCHHEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCH
SVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIVDVEAVIERVERENGIEVG
HHHHEEEECCCCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQELFFARSMIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCHHCCCCCHHHHHHHHHHHH
HAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTEKE
HHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHH
IDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKDTSRALVHFALKTFDYS
CHHHHHHEEECCCCCCHHEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCH
SVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIVDVEAVIERVERENGIEVG
HHHHEEEECCCCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQELFFARSMIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCHHCCCCCHHHHHHHHHHHH
HAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTEKE
HHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHH
IDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]