BacMap

Definition	Streptococcus pyogenes MGAS10750 chromosome, complete genome.
Accession	NC_008024
Length	1,937,111

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The map label for this gene is ydfG [C]

Identifier: 94994398

GI number: 94994398

Start: 949339

End: 950112

Strand: Direct

Name: ydfG [C]

Synonym: MGAS10750_Spy1002

Alternate gene names: 94994398

Gene position: 949339-950112 (Clockwise)

Preceding gene: 94994397

Following gene: 94994400

Centisome position: 49.01

GC content: 42.38

Gene sequence:

>774_bases
TTGAGGGTGAGGAAATGTATGGGAAATATTGCCTTAGTAACAGGGGCTTCAGCCGGTTTTGGCAGAGCCATTGTCGAACA
CTTAATTGCAGATGGGATAAAGGTTATTGGTGCTTCTCGTCGTCTTGAGAAACTCAAGGCCTTAGAAACGAGCTTTGGGT
CGGACAACTTTTACCCTTTGCAGATGGATGTCACAGATACCAAAGCGATTGATGATGCTTTGACAAGTCTACCAAATCAG
TGGCAAGATATTACTATTTTAGTGAATAATGCAGGCTTGGCATTGGGACTTGATAAGGCTTATGAAGCCGATTTTGAGAA
TTGGATGACGATGATTAACACTAATATTGTTGGGTTGATTTATCTCACACGTCAATTATTACCACATATGGTCTCCAAAG
ATGATGGTATTATTATTAATTTAGGGTCAACCGCAGGGACAATTCCCTATCCGGGAGCTAATATTTATGGGGCTAGCAAG
GCTTTTGTTAAGCAGTTCTCACTCAATTTACGAGCTGATTTAGCAGGTAGCCATATACGTGTGACCAATATTGAACCCGG
TCTATGTGAAGGGACAGAATTTTCAAAGGTTCGCTTTAATGGTGATGAGGCACGGGTGAAGGCCATTTATCAAGGAGCAC
ATGCCATTCAACCTCAAGATATTGCGTCGACTGTATCATGGGTGATTCATCAGCCCCCTCATGTTAATGTTAATCGTATT
GAGCTAATGCCAGTGTCGCAAAGTTATGGACCGCAACCAGTTACTCGTGACTAG

Upstream 100 bases:

>100_bases
CCCTTGATATAGGATCCTAACCGCTAAGTGATGTGTTAGAAGTTGTCCTAAGACTAATTGACATTATTAAAAACGAGTTG
GCCAGACCATCTCGTTTTTT

Downstream 100 bases:

>100_bases
CAAGGGATGAGTCCATAAGAATAATAATCTTTAGAAAAATGGTTTACTGGAATGGATTATTCTTTATAAGTGAGACTTAC
CGATTTAGTCATCAAAAAAA

Product: Short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRVRKCMGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALETSFGSDNFYPLQMDVTDTKAIDDALTSLPNQ
WQDITILVNNAGLALGLDKAYEADFENWMTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASK
AFVKQFSLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRI
ELMPVSQSYGPQPVTRD

Sequences:

>Translated_257_residues
MRVRKCMGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALETSFGSDNFYPLQMDVTDTKAIDDALTSLPNQ
WQDITILVNNAGLALGLDKAYEADFENWMTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASK
AFVKQFSLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRI
ELMPVSQSYGPQPVTRD
>Mature_257_residues
MRVRKCMGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALETSFGSDNFYPLQMDVTDTKAIDDALTSLPNQ
WQDITILVNNAGLALGLDKAYEADFENWMTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASK
AFVKQFSLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRI
ELMPVSQSYGPQPVTRD

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=31.4516129032258, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI7705855, Length=201, Percent_Identity=30.3482587064677, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI4557649, Length=191, Percent_Identity=31.413612565445, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542939, Length=188, Percent_Identity=34.0425531914894, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=31.3829787234043, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI22507405, Length=195, Percent_Identity=31.7948717948718, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI150247226, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI224922801, Length=165, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=27.7486910994764, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI119392083, Length=185, Percent_Identity=31.3513513513514, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4504503, Length=183, Percent_Identity=31.6939890710383, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19743808, Length=178, Percent_Identity=28.6516853932584, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40548397, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI214010158, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI214010156, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI22758144, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI32483357, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=184, Percent_Identity=26.6304347826087, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680133, Length=184, Percent_Identity=26.6304347826087, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI17738292, Length=184, Percent_Identity=26.6304347826087, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=204, Percent_Identity=26.9607843137255, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=54.6558704453441, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=32.4894514767932, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI2367175, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=26.0330578512397, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=33.1578947368421, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786701, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=29.535864978903, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=241, Percent_Identity=29.4605809128631, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=242, Percent_Identity=26.8595041322314, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=237, Percent_Identity=26.5822784810127, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=184, Percent_Identity=29.8913043478261, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=249, Percent_Identity=27.3092369477912, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=243, Percent_Identity=27.5720164609054, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=242, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=185, Percent_Identity=25.9459459459459, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557780, Length=211, Percent_Identity=27.0142180094787, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=207, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=28.1553398058252, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560176, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=252, Percent_Identity=37.6984126984127, Blast_Score=156, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322067, Length=182, Percent_Identity=31.8681318681319, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=191, Percent_Identity=27.2251308900524, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007236, Length=253, Percent_Identity=26.8774703557312, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI281364494, Length=254, Percent_Identity=28.740157480315, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24640442, Length=200, Percent_Identity=33.5, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI23397609, Length=180, Percent_Identity=34.4444444444444, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24641388, Length=254, Percent_Identity=26.7716535433071, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI116007234, Length=253, Percent_Identity=28.8537549407115, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571387, Length=254, Percent_Identity=30.3149606299213, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21358495, Length=186, Percent_Identity=32.258064516129, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648693, Length=256, Percent_Identity=25.390625, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355889, Length=256, Percent_Identity=25.390625, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24643142, Length=181, Percent_Identity=33.7016574585635, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641232, Length=254, Percent_Identity=28.3464566929134, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=31.3829787234043, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161076933, Length=188, Percent_Identity=31.3829787234043, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24663911, Length=259, Percent_Identity=27.7992277992278, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=31.2169312169312, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28574402, Length=189, Percent_Identity=31.2169312169312, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=28.6290322580645, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648944, Length=246, Percent_Identity=27.2357723577236, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=31.6939890710383, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007232, Length=186, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24580925, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357041, Length=228, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=192, Percent_Identity=26.5625, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=24.2677824267782, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584752, Length=198, Percent_Identity=29.2929292929293, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28035; Mature: 28035

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRKCMGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALETSFGSDNFYPL
CCHHHHHCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
QMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENWMTMINTNIVGLI
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHHHHHHCCHHHHH
YLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQFSLNLRADLAGSHIR
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEE
VTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRI
EEECCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
ELMPVSQSYGPQPVTRD
EEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRVRKCMGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALETSFGSDNFYPL
CCHHHHHCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
QMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENWMTMINTNIVGLI
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHHHHHHCCHHHHH
YLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQFSLNLRADLAGSHIR
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEE
VTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRI
EEECCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
ELMPVSQSYGPQPVTRD
EEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]