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The map label for this gene is potC [H]

Identifier: 94994375

GI number: 94994375

Start: 927603

End: 928379

Strand: Direct

Name: potC [H]

Synonym: MGAS10750_Spy0979

Alternate gene names: 94994375

Gene position: 927603-928379 (Clockwise)

Preceding gene: 94994374

Following gene: 94994376

Centisome position: 47.89

GC content: 37.19

Gene sequence:

>777_bases
ATGAAAAAATTTGCCAATCTTTATTTAGCGAGTGTCTTTGTTTTACTCTACATTCCTATTTTTTATTTGATTTTCTATTC
TTTCAACAAAGGTGGGGATATGAATGGTTTTACAGGATTTACCCTTGAGCATTACCAAACCATGTTTGAGGATAGTCGTC
TCATGACAATCTTACTGCAAACCTTTGTTCTTGCTTTTAGTAGCGCTCTACTAGCAACGATTATTGGGACCTTTGGTGCT
ATCTTTATCCACCATGTTAGAGGTAAGTACCAAAATGCCATGCTATCAGCCAATAATGTCTTGATGGTATCACCAGATGT
CATGATTGGGGCTTCCTTTTTAATTCTTTTTACATCATTGAAGTTTCAGCTGGGCATGTCTTCAGTTTTATTAAGTCATA
TTGCTTTTTCGATTCCTATTGTGGTTTTGATGGTATTGCCGCGCTTGAAAGAGATGAATCAGGACATGGTCAACGCCGCT
TATGATTTGGGAGCTAATTATTTCCAAATGCTCAAAGAAGTCATGCTGCCATACTTAACACCAGGGATTATTGCTGGTTA
TTTTATGGCCTTTACCTATTCCTTAGATGATTTTGCAGTGACTTTCTTTTTGACTGGAAATGGTTTTACTACTTTATCTG
TTGAGATTTATTCGCGGGCTCGTCAGGGAATTTCCTTGGATATCAATGCTTTGTCAACCATCGTTTTCTTTTTCTCCATC
CTCTTAGTGATCGGTTATTATTATATGTCACAGGACAAGGAGGAAAAACATGCGTAA

Upstream 100 bases:

>100_bases
ATTTTTTGACCACCCAAAACTGGGGAATGGGATCAACAATTGGTGTCGTCTTGATTTTGACCATGGTTGCTATTATGTGG
CTCACAAAGGAGAAAAGTAA

Downstream 100 bases:

>100_bases
ACTTTATTCCTTTCTAGCAGGAGTTTTGGGTGTTATTGTTATTTTAACAAGTCTTTCTTTCATCTTGCAGAAAAAATCGG
GTTCTGGTAGTCAATCGGAT

Product: Spermidine/putrescine transport system permease protein potC

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEHYQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGA
IFIHHVRGKYQNAMLSANNVLMVSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYSRARQGISLDINALSTIVFFFSI
LLVIGYYYMSQDKEEKHA

Sequences:

>Translated_258_residues
MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEHYQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGA
IFIHHVRGKYQNAMLSANNVLMVSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYSRARQGISLDINALSTIVFFFSI
LLVIGYYYMSQDKEEKHA
>Mature_258_residues
MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEHYQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGA
IFIHHVRGKYQNAMLSANNVLMVSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYSRARQGISLDINALSTIVFFFSI
LLVIGYYYMSQDKEEKHA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=36.7521367521368, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1787081, Length=257, Percent_Identity=31.5175097276265, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787714, Length=249, Percent_Identity=23.6947791164659, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788764, Length=71, Percent_Identity=42.2535211267606, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29114; Mature: 29114

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEHYQTMFEDSRLMTILLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHH
TFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLMVSPDVMIGASFLILFTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHH
KFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAAYDLGANYFQMLKEVMLPYLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYSRARQGISLDINALSTIVFFFSI
HHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCEEEHHHHHHHHHHHHH
LLVIGYYYMSQDKEEKHA
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEHYQTMFEDSRLMTILLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHH
TFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLMVSPDVMIGASFLILFTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHH
KFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAAYDLGANYFQMLKEVMLPYLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYSRARQGISLDINALSTIVFFFSI
HHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCEEEHHHHHHHHHHHHH
LLVIGYYYMSQDKEEKHA
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]