Click here to switch to the map view.

The map label for this gene is spaC [H]

Identifier: 94994353

GI number: 94994353

Start: 909676

End: 910932

Strand: Direct

Name: spaC [H]

Synonym: MGAS10750_Spy0957

Alternate gene names: 94994353

Gene position: 909676-910932 (Clockwise)

Preceding gene: 94994352

Following gene: 94994354

Centisome position: 46.96

GC content: 30.63

Gene sequence:

>1257_bases
TTGGAGCCACATATGACACCTCAAATTAAACAGATAGTAGATTACATTGCAGATAGTTTTATAAATTATGAACAGATAGT
AGCTGAAAGTGAGAATAAAGTACTAATTAATATTGAATCTAAATATAGAAATACCTTTTTTGATAAATCTCTGAGTCATG
GTGTGCCATCATTAATCTTAATGTATAGTTCACTATATAAAGTGACAAAAGATGAGAGATATCTAACATTCTCCAACATA
TACGTTGAGAAATTAGTAGACATAATCTCTAGAGATGGTATAGAATCTCCGTCTCTCTATGCTGGCACTGCAGGTATTGC
ATTAGCTATTAAAGAAGCGAGTATATCTGGAAAGTATTATCCGAAATTATTATCATCCTTAAATTGTCTTCTAAAAGAAC
AAATTAAAGACAAATTGGTAGTAAGTTTTTCTAATATTGAGAAAGGAATTATTGAGCCATATGATTATGATATGGTTAAC
GGATTTAGTGGAATAACTAATTACTTACTCCTTGAACAAGAATTTTTTTCTGTAGAGTTAAATCAAATTGGAAATTATCT
TTTGAAATATATTGAGACAATTTTAAATAAGGTAACTAATTGTTCTGAAGATAGAGAAGCTGAATTTGATCTAGGAATTG
CACATGGAATTACTGGTCCTATGCTAATCCTAGCAAAATTAAAATCAGAAAAAATTTTGAGTGTAGAAGTAGGAGATATA
CTGAATAAAGCTATAAATTTAATGTTTTTATTTAGAAGGGATGACAAACTATGGCCTGGAAAAATTTATACTAGTAATAT
TTTGGATCTTGATTTAAATTATCTTCCTACTAGAATGGCATGGTGTTACGGTACGCCTGGAACTGCAGTTGCCCTTTTTA
AAATGTGTCAATTGATAGATTTAAATTTTATTGACGATATTAATGAAAGTTTAATTGCTCAGATGAGAAGTTCAGACAAA
AATGTCTATTCTCTTACAATGTGCCATGGTTTGGCAGGAGTAACTTTTATATATGACTTGATTGGTAAAAATTATTCAAG
TGAGAGGCTAACTCGCTTTGCAGAAGAGCTTCGCCAACAAATAATTACATCGTTTTCAACTACAAAAGTATTTGGGTATA
CTGACAGAGAAAAATTTGGAGAAATAGAAGTTGAACTGGAGTCAATAGGGATATTGCAAGGGGTATCAGGGATAGTGTTA
TTCTTATTAAATCCTTACAGTGACGAGGAGCTATTGTGGCAAAGAATATTTATTTAA

Upstream 100 bases:

>100_bases
AAAATTTTGTATCTAGATAATGGATGTATATCTGAAACAGGAAGTTTCGCTGATTTAAATATTAAAGGAATGAAGTTTAA
AAACTTATTAGATAAAGAAA

Downstream 100 bases:

>100_bases
TTTGAAAAGGAGAACAAAATGTATAAGGTATTTCCAACTGGTATGATTCGTATTCCATTGCAAAAACAAGAATTTTATAA
TAAAGACTATGAAGATTTAA

Product: Lanthionine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MEPHMTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFDKSLSHGVPSLILMYSSLYKVTKDERYLTFSNI
YVEKLVDIISRDGIESPSLYAGTAGIALAIKEASISGKYYPKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVN
GFSGITNYLLLEQEFFSVELNQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPMLILAKLKSEKILSVEVGDI
LNKAINLMFLFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLIDLNFIDDINESLIAQMRSSDK
NVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQIITSFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVL
FLLNPYSDEELLWQRIFI

Sequences:

>Translated_418_residues
MEPHMTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFDKSLSHGVPSLILMYSSLYKVTKDERYLTFSNI
YVEKLVDIISRDGIESPSLYAGTAGIALAIKEASISGKYYPKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVN
GFSGITNYLLLEQEFFSVELNQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPMLILAKLKSEKILSVEVGDI
LNKAINLMFLFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLIDLNFIDDINESLIAQMRSSDK
NVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQIITSFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVL
FLLNPYSDEELLWQRIFI
>Mature_418_residues
MEPHMTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFDKSLSHGVPSLILMYSSLYKVTKDERYLTFSNI
YVEKLVDIISRDGIESPSLYAGTAGIALAIKEASISGKYYPKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVN
GFSGITNYLLLEQEFFSVELNQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPMLILAKLKSEKILSVEVGDI
LNKAINLMFLFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLIDLNFIDDINESLIAQMRSSDK
NVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQIITSFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVL
FLLNPYSDEELLWQRIFI

Specific function: Could be implicated in the processing or the export process of the subtilin lantibiotic [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To S.epidermidis epiC and L.lactis nisC [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007822
- InterPro:   IPR020452 [H]

Pfam domain/function: PF05147 LANC_like [H]

EC number: NA

Molecular weight: Translated: 47629; Mature: 47629

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPHMTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFDKSLSHGVPSLIL
CCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHH
MYSSLYKVTKDERYLTFSNIYVEKLVDIISRDGIESPSLYAGTAGIALAIKEASISGKYY
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCCCHH
PKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVNGFSGITNYLLLEQEFFSVEL
HHHHHHHHHHHHHHHHHHHEEEHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHH
NQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPMLILAKLKSEKILSVEVGDI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCEEEEHHHHH
LNKAINLMFLFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLID
HHHHHHEEEEEECCCCCCCCCEEECCEEEECCCCCCCHHEEEECCCHHHHHHHHHHHHHC
LNFIDDINESLIAQMRSSDKNVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQ
CHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IITSFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVLFLLNPYSDEELLWQRIFI
HHHHCCCCEEECCCCHHHHCCEEEEHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MEPHMTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFDKSLSHGVPSLIL
CCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHH
MYSSLYKVTKDERYLTFSNIYVEKLVDIISRDGIESPSLYAGTAGIALAIKEASISGKYY
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCCCHH
PKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVNGFSGITNYLLLEQEFFSVEL
HHHHHHHHHHHHHHHHHHHEEEHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHH
NQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPMLILAKLKSEKILSVEVGDI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCEEEEHHHHH
LNKAINLMFLFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLID
HHHHHHEEEEEECCCCCCCCCEEECCEEEECCCCCCCHHEEEECCCHHHHHHHHHHHHHC
LNFIDDINESLIAQMRSSDKNVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQ
CHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IITSFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVLFLLNPYSDEELLWQRIFI
HHHHCCCCEEECCCCHHHHCCEEEEHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1539969; 1735728 [H]