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The map label for this gene is hflX [H]

Identifier: 94994213

GI number: 94994213

Start: 790709

End: 791959

Strand: Direct

Name: hflX [H]

Synonym: MGAS10750_Spy0817

Alternate gene names: 94994213

Gene position: 790709-791959 (Clockwise)

Preceding gene: 94994212

Following gene: 94994214

Centisome position: 40.82

GC content: 39.65

Gene sequence:

>1251_bases
TTGGTAAAGGTGATGATTGAGACAAAGCGTCAGCAAGAAAGAGTGATTCTTTTAGGAGTTGAGCTTCAGACAACAGAACA
TTTTGATATGTCCATGACAGAATTAGCTAATCTTGCCAAAACAGCTGGCGTCAAAGTTATGGCAAGTTTCAGCCAAAAAC
GAGAACGTTACGACAGCAAAACCTTTATCGGCTCAGGGAAACTGGATGAGATTAAGGCGATTGTGGAAGCTGATGAGATT
GATGCAGTTATTGTGAACAATCGGTTGACTGCTAGGCAAAATGCTAATCTAGAAGCTGTTTTAGAGGTAAAAGTCATTGA
CCGTATGCAGTTAATCTTAGATATTTTTGCCATGCGTGCCAGAAGCCATGAGGGCAAATTACAAGTACACCTTGCCCAAT
TGAAATATATGTTACCTCGTTTGGTTGGACAGGGCATCATGTTAAGTCGTCAAGCAGGTGGTATTGGGAGCCGTGGACCA
GGTGAAAGCCAACTAGAGTTAAATCGCCGTTCGATTCGTCATCAGATTGCTGATATTGAACGCCAATTAACTCAGGTAGA
GAAAAATCGTCAAACAATTAGAGATCGTCGTGTGGGTTCAGATACCTTTAAAATTGGCTTGATTGGCTACACCAATGCTG
GCAAGTCAACCATTATGAACTTGTTGACAGATGACAGCCACTATGAAGCCAATGAATTATTTGCTACCTTAGATGCAACT
ACAAAGCAACTCTATTTAGAAAATCAATTTCAAGCAACCTTAACAGACACCGTAGGCTTTATTCAAGACTTGCCAACGGA
ATTAGTGGCTGCTTTTAAATCAACCCTAGAAGAAAGCAAATATGTGGATTTGCTGTTACATGTGATTGATGCGAGTGATC
CCAATCATAGTGAGCAAGAAAAAGTGGTTTTAAACCTTCTAAAAGAGCTAGACATGCTTAATATTCCGCGTTTAGCTATT
TATAACAAGGTGGATATAGCAGAACAATTCACAGCTACTGCTTTTCCAAATATCAGGATTTCAGCCCGTTCAAAGGATAG
CAAAATTCTCTTGAGACGTTTAATCATTGACCAAATTCGAGACCAGTTTGTTCCTTTTAGAATCAAAGTGCATCAAGACA
AGGCGTACAAGCTATATGATTTGAATCGAGTTGCTCTTTTAGACCACTACACGTTTGACCAAGAAATAGAGGATATTTCG
GGCTACATTTCCCCAAAACAGCAATGGAGACTTGACGATTTTTATGAATAA

Upstream 100 bases:

>100_bases
TAGGGTCAGGGATTTTCTTGGTCAGAAAGAGAAGTCATGACGCAAAATTAGCAGAATCTGTTGAAGATATGTTATAATAG
AATTTACGGAATTTGGAGGA

Downstream 100 bases:

>100_bases
TTATATTGATTTAGCAAAAACCTATGGTGGATTTACTAGTCTGGATACCAACTACCTAAACCATCTGTTAGCCAGTTTGA
CAGACCAGCAAAAACTAGCT

Product: GTP-binding protein hflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASFSQKRERYDSKTFIGSGKLDEIKAIVEADEI
DAVIVNNRLTARQNANLEAVLEVKVIDRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGP
GESQLELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDAT
TKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAI
YNKVDIAEQFTATAFPNIRISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDIS
GYISPKQQWRLDDFYE

Sequences:

>Translated_416_residues
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASFSQKRERYDSKTFIGSGKLDEIKAIVEADEI
DAVIVNNRLTARQNANLEAVLEVKVIDRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGP
GESQLELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDAT
TKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAI
YNKVDIAEQFTATAFPNIRISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDIS
GYISPKQQWRLDDFYE
>Mature_416_residues
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASFSQKRERYDSKTFIGSGKLDEIKAIVEADEI
DAVIVNNRLTARQNANLEAVLEVKVIDRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGP
GESQLELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDAT
TKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAI
YNKVDIAEQFTATAFPNIRISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDIS
GYISPKQQWRLDDFYE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=193, Percent_Identity=36.2694300518135, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310133118, Length=193, Percent_Identity=36.2694300518135, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI310124269, Length=185, Percent_Identity=36.2162162162162, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124267, Length=185, Percent_Identity=36.2162162162162, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124171, Length=185, Percent_Identity=36.2162162162162, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124169, Length=185, Percent_Identity=36.2162162162162, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1790615, Length=333, Percent_Identity=44.1441441441441, Blast_Score=265, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17561038, Length=308, Percent_Identity=29.8701298701299, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24650079, Length=309, Percent_Identity=31.7152103559871, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47641; Mature: 47641

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASFSQKRERYDSK
CEEEEEECCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
TFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVIDRMQLILDIFAMRA
EEECCCCHHHHHHHHHHCCCCEEEECCCEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
RSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQLELNRRSIRHQIADIE
CCCCCEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDAT
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
TKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQE
HHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
KVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNIRISARSKDSKILLRRLIIDQIR
HHHHHHHHHCCCCCCCCHHEECCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
DQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDISGYISPKQQWRLDDFYE
HCCCCEEEEEECCCCEEEEECCEEEEEECCCCHHHHHHHHCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASFSQKRERYDSK
CEEEEEECCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
TFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVIDRMQLILDIFAMRA
EEECCCCHHHHHHHHHHCCCCEEEECCCEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
RSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQLELNRRSIRHQIADIE
CCCCCEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDAT
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
TKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQE
HHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
KVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNIRISARSKDSKILLRRLIIDQIR
HHHHHHHHHCCCCCCCCHHEECCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
DQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDISGYISPKQQWRLDDFYE
HCCCCEEEEEECCCCEEEEECCEEEEEECCCCHHHHHHHHCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]