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The map label for this gene is arsC [H]

Identifier: 94994185

GI number: 94994185

Start: 763195

End: 763641

Strand: Direct

Name: arsC [H]

Synonym: MGAS10750_Spy0789

Alternate gene names: 94994185

Gene position: 763195-763641 (Clockwise)

Preceding gene: 94994184

Following gene: 94994186

Centisome position: 39.4

GC content: 41.16

Gene sequence:

>447_bases
TTGATAATGGAAGAAATCACGATTTATCATAATCCAAACTGTGGCACTTCACGTAATGTTCTTGCCATGATTCGCCATGC
AGGTATTGAGCCTACTATTATTGAGTATTTGCAGACGCCACCTAATCGGGAGACTTTAATTGAGCTCTTACAATCGATGG
GAATCTCTGCGCGAGAACTCTTGCGAACCAATGTTCCTGAATTTGAGGCTCATGGATTAGCAAATCAAGCAGTAGCTGAG
AAAGACGTTATTAATGCCATGTTGACGGATCCAATTTTGATCAATCGTCCTATTGTTGTGACTCGCAAAGGAGTAAAACT
TTGCCGTCCTTCTGAGACCTTACTGGATATTCTTCCTGTTCCCCTGCCTAGTCCTTATATTAAAGAGGATGGCGAGATTG
TGAACCCTATTGAGGTAAAAGGAGAAAAAGATGTCATTGATGACTAA

Upstream 100 bases:

>100_bases
TTTTGCAGATATTTCAGCGACTGTTGCAGAAAATTTTGGAGTTGATACAGCCATGATTGGGGAGTCATTCCTTGGTCACT
TAAAATAAGAAAGTTAGTAA

Downstream 100 bases:

>100_bases
AATTAACGAAACAAAAGACTTTTTAGTTGCTAAAGGAATTGAAGCTCCAGAATTTGGATTAATTCTGGGTTCAGGCCTTG
GTGAACTTGCTGAAGAAGTA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MIMEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLIELLQSMGISARELLRTNVPEFEAHGLANQAVAE
KDVINAMLTDPILINRPIVVTRKGVKLCRPSETLLDILPVPLPSPYIKEDGEIVNPIEVKGEKDVIDD

Sequences:

>Translated_148_residues
MIMEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLIELLQSMGISARELLRTNVPEFEAHGLANQAVAE
KDVINAMLTDPILINRPIVVTRKGVKLCRPSETLLDILPVPLPSPYIKEDGEIVNPIEVKGEKDVIDD
>Mature_148_residues
MIMEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLIELLQSMGISARELLRTNVPEFEAHGLANQAVAE
KDVINAMLTDPILINRPIVVTRKGVKLCRPSETLLDILPVPLPSPYIKEDGEIVNPIEVKGEKDVIDD

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=132, Percent_Identity=58.3333333333333, Blast_Score=153, Evalue=4e-39,
Organism=Escherichia coli, GI1788841, Length=118, Percent_Identity=38.135593220339, Blast_Score=94, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 16501; Mature: 16501

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLIELLQSMGISAREL
CCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHH
LRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKGVKLCRPSETLLDILPV
HHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCCHHHHHHCCC
PLPSPYIKEDGEIVNPIEVKGEKDVIDD
CCCCCCCCCCCCEECCEECCCCCCCCCC
>Mature Secondary Structure
MIMEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLIELLQSMGISAREL
CCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHH
LRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKGVKLCRPSETLLDILPV
HHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCCHHHHHHCCC
PLPSPYIKEDGEIVNPIEVKGEKDVIDD
CCCCCCCCCCCCEECCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]