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The map label for this gene is fms [H]

Identifier: 94994165

GI number: 94994165

Start: 741963

End: 742373

Strand: Direct

Name: fms [H]

Synonym: MGAS10750_Spy0769

Alternate gene names: 94994165

Gene position: 741963-742373 (Clockwise)

Preceding gene: 94994164

Following gene: 94994167

Centisome position: 38.3

GC content: 35.04

Gene sequence:

>411_bases
ATGATTAGAGAAATCATAACAGATCATTTTTTATTAAAGCAAAAAGCACAAGTCGCCAAGAAAGAAGATCTATGGATTGG
CCAAGATTTACAAGATACCTTAGCCTTTTATAGGCAGGAATGTCTTGGGATGGCTGCCAATATGATTGGTGAACAAAAAC
GCATTGTTATTGTGAGTATGGGATTTATTGATTTGGTGATGTTTAATCCTGTGATGGTTTCTAAAAAGGGAATTTACCAA
ACTAAAGAATCTTGTTTGTCATTATCTGGCTATCGCAAAACACAGCGGTATGATAAGATTACTGTTGAGTATTTGGACCA
TAATTGGCGACCAAAGCGTTTAAACTTAACAGGCCTAACTGCTCAAATATGCCAGCACGAATTAGATCATCTAGAAGGTA
TTTTAATTTAA

Upstream 100 bases:

>100_bases
CATCTGATGTTTTAAACAGATGATACTAAGACTATCATATGGTGATAATAGTCCATTGAACATGTAGTTTATGAATTAAA
AAAAGTTTAAGGAGATAAGA

Downstream 100 bases:

>100_bases
CAAAAAACCTAGAGTAGGACACTTTAGGTTTTTTTGGCGAAAATGCCTGATTATATAAGGATGATCAATTACTAGTAAAC
GCTAGGATTTTCTTTTTTTA

Product: peptide deformylase

Products: NA

Alternate protein names: PDF; Polypeptide deformylase [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MIREIITDHFLLKQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMAANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQ
TKESCLSLSGYRKTQRYDKITVEYLDHNWRPKRLNLTGLTAQICQHELDHLEGILI

Sequences:

>Translated_136_residues
MIREIITDHFLLKQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMAANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQ
TKESCLSLSGYRKTQRYDKITVEYLDHNWRPKRLNLTGLTAQICQHELDHLEGILI
>Mature_136_residues
MIREIITDHFLLKQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMAANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQ
TKESCLSLSGYRKTQRYDKITVEYLDHNWRPKRLNLTGLTAQICQHELDHLEGILI

Specific function: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions

COG id: COG0242

COG function: function code J; N-formylmethionyl-tRNA deformylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polypeptide deformylase family [H]

Homologues:

Organism=Escherichia coli, GI1789682, Length=104, Percent_Identity=33.6538461538462, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000181 [H]

Pfam domain/function: PF01327 Pep_deformylase [H]

EC number: =3.5.1.88 [H]

Molecular weight: Translated: 15831; Mature: 15831

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREIITDHFLLKQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMAANMIGEQKRIVIVSM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEYLDHNWRPKRLNLTGLT
HHHHHHHHCCHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCCCCCEECCCHHH
AQICQHELDHLEGILI
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIREIITDHFLLKQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMAANMIGEQKRIVIVSM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEYLDHNWRPKRLNLTGLT
HHHHHHHHCCHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCCCCCEECCCHHH
AQICQHELDHLEGILI
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9572951 [H]