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The map label for this gene is pepT [H]

Identifier: 94994097

GI number: 94994097

Start: 679517

End: 680752

Strand: Direct

Name: pepT [H]

Synonym: MGAS10750_Spy0701

Alternate gene names: 94994097

Gene position: 679517-680752 (Clockwise)

Preceding gene: 94994096

Following gene: 94994098

Centisome position: 35.08

GC content: 39.16

Gene sequence:

>1236_bases
TTGAGGTGGCCTATGAAGTACGATAACTTGTTAGATCGATTTATAAAATATGTCAAAGTGAATACAAGAAGCGATCCAGA
CAGTGAGACTACTCCTAGTACGGAGAGTCAAGAAGCATTTGCCTTAACGATTTTAAAGCCTGAAATGGAGGCAATTGGTT
TGCAAGATGTTCATTATAATCCAGTTAATGGCTATCTTATTGGAACTCTGCCTGCCAATAATCCAACCTTGACGCGTAAA
ATTGGTTTTATAGCCCATATGGATACGGCTGATTTCAATGCTGAAAATGTTAATCCGCAGATTATTGACAATTATCAAGG
AGGGGACATTACACTTGGCAGTTCTAATTATAAGTTGGATCCAAAAGCATTTCCGAATCTTAATAATTATATCGGTCAAA
CATTGATTACCACTGATGGGACTACACTTTTAGGGGCAGATGATAAATCTGGTATTGCTGAAATCATGACAGCAATAGAA
TTCTTAACATCACAACCACAAATAGAGCACTGTGACATTAAAGTGGCTTTTGGCCCTGATGAAGAGATTGGGGTCGGAGC
TGATAAGTTTGAGGTGGCTGATTTTGAGGTGGATTTTGCTTATACTATGGATGGCGGTCCTTTAGGCGAATTGCAATATG
AAACTTTCAGCGCTGCAGCTCTAGAAGTGACTTTTTTAGGCAGAAATGTTCATCCTGGTACGGCTAAGGATCAAATGATT
AATGCCCTTCAGTTAGCAATAGATTTTCATGAGAAGCTACCTGCTAAAGAGCGGCCTGAATACACAGATGGTTATCAAGG
CTTCTATCACTTAACGGGACTAACTGGAACAGTTGAAGAGGCACGGGCATCTTACATTATTCGTGATTTTGAAGAAGCAT
CATTTGAAGCTAGAAAAGTGAAAGTTGAAAATATAGCTCAATCGATGAATGCTCAGCTAGGAACAAAACGTGTCTTGGTA
GAGCTTAATGACCAATACTACAATATGAAAAAAGTTATCGAAAAAGATATGACCGCTATTGAGTTAGCTAAAGAAGTAAT
GGAAGAGCTTACTATCAAGCCTGTAATCGAACCCATACGTGGAGGAACAGATGGCTCTAAAATTTCATTTATGGGTATTC
CCACTCCTAATATTTTTGCAGGGGGTGAGAATATGCACGGGCGTTTTGAGTTTGTTAGCTTACAAACGATGGAGAGAGCT
GTCGATGTCATTATTGGACTTGTTTGCAAAGCCTAA

Upstream 100 bases:

>100_bases
TTTTAGATATTATCATTAAACTCTTAATTAGAGGCTTTAAAAAACTTAGCTTGAATAAGTATTTTAAAGCCTTTTATGCT
ATAATTAAATTGAGAAATTA

Downstream 100 bases:

>100_bases
TTATCATGTAATTGATATTTAGTGGAAGGGGCTTATAAAAATGATTAAACTATTTGGTAAAATAAGGTATCACTGGCAGC
CAGAGTTGTCTTGGTCTATT

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MRWPMKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRK
IGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIE
FLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMI
NALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLV
ELNDQYYNMKKVIEKDMTAIELAKEVMEELTIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERA
VDVIIGLVCKA

Sequences:

>Translated_411_residues
MRWPMKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRK
IGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIE
FLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMI
NALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLV
ELNDQYYNMKKVIEKDMTAIELAKEVMEELTIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERA
VDVIIGLVCKA
>Mature_411_residues
MRWPMKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRK
IGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIE
FLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMI
NALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLV
ELNDQYYNMKKVIEKDMTAIELAKEVMEELTIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERA
VDVIIGLVCKA

Specific function: Cleaves the N-terminal amino acid of tripeptides [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family [H]

Homologues:

Organism=Escherichia coli, GI1787372, Length=400, Percent_Identity=50.5, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.11.4 [H]

Molecular weight: Translated: 45599; Mature: 45599

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWPMKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYN
CCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEEECCCHHHCCCCCCEEC
PVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLD
CCCCEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCEEEECCCCCEEEECCCCCEEC
PKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTSQPQIEHCDIKVAFGPD
CHHCCCHHHHHCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCC
EEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMI
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCCCCCHHHHH
NALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHEE
KVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMTAIELAKEVMEELTIKPVIEPIR
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERAVDVIIGLVCKA
CCCCCCEEEEEECCCCCEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRWPMKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYN
CCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEEECCCHHHCCCCCCEEC
PVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLD
CCCCEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCEEEECCCCCEEEECCCCCEEC
PKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTSQPQIEHCDIKVAFGPD
CHHCCCHHHHHCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCC
EEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMI
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCCCCCHHHHH
NALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHEE
KVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMTAIELAKEVMEELTIKPVIEPIR
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERAVDVIIGLVCKA
CCCCCCEEEEEECCCCCEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]