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The map label for this gene is pheT [H]

Identifier: 94994069

GI number: 94994069

Start: 645171

End: 647591

Strand: Direct

Name: pheT [H]

Synonym: MGAS10750_Spy0673

Alternate gene names: 94994069

Gene position: 645171-647591 (Clockwise)

Preceding gene: 162139187

Following gene: 94994070

Centisome position: 33.31

GC content: 42.17

Gene sequence:

>2421_bases
TTGGGCACTAAAATTATGTTAGTATCTTATAAATGGTTAAAAGAATTAGTAGATATCGATGTGACACCAGCAGCACTTGC
TGAGAAAATGTCGACAACGGGTATCGAGGTAGAAGGAATTGAAGTCCCTGCAGAAGGTTTATCAAAACTGGTTGTGGGGC
ATGTGCTTTCTTGTGAAGATGTGCCAGAGACACATTTGCATTTGTGTCAGGTAGATACAGGTGATGAAACGCCACGTCAA
ATTGTGTGTGGCGCACCAAATGTGAAAGCAGGGATTAAGGTTATCGTGGCTGTGCCAGGTGCTCGTATTGCGGATAACTA
TAAAATCAAAAAAGGCAAAATCCGCGGCATGGAATCTCTTGGTATGATTTGTTCCTTGCAAGAACTTGGTTTGTCAGATA
GTATCATTCCAAAAGAATTTTCAGACGGTATTCAAATCTTGCCAGAGGAGGCTGTGCCAGGTGATGCTATTTTTAAATAC
CTGGACTTGGACGATCATATCATTGGATTGTCCATTACACCTAACCGTGCTGATGCGCTTTCTATGCGAGGTGTGGCACA
TGAAGTCGCAGCTATTTATGGCAAGTCAGTATCATTCCCCCCAAAAAATCTACAAGAATCTGATAAGGCAACTTCAGAAG
CCATTGAAGTGGCCATTGCCTCTGATAACGTTCTAACTTACGCTAGCCGTGTCGTTGAAAATGTCAAAGTTAAGCCAAGT
CCACAATGGTTGCAAAACCTTTTAATGAATGCCGGTATTCGTCCTATTAATAATGTGGTTGATGTGACCAACTATGTGCT
CTTGTATTTTGGTCAACCTATGCATGCTTTTGATTATGATAAATTTGAAGACCATAAGATTGTGGCGCGTGCGGCTCGTC
AAGGGGAAAGTTTAGTCACACTTGATGGTGAAAAACGGGATTTGACCACTGAGGATCTTGTTATTACCGTGGCTGACAAA
CCAGTTGCTTTGGCAGGTGTTATGGGTGGTCAAGCCACTGAAATTGATGCCAACTCTCAGACGGTTGTTCTTGAAGTTGC
TGTTTTTGATGGCAAATCGATTCGTAAAACCAGTGGTCGTTTAAACCTTCGTTCGGAATCCTCTTCACGTTTTGAAAAAG
GGGTTAACTATGCAACTGTTTTAGAAGCGCTTGACTTTGCAGCGGCTATGTTACAAGAATTAGCAGAAGGTCAAGTCTTA
TCAGGCCATGTTCAAGCTGGACAATTGCCAACAGAACCTGTTGAAGTCTCAACTAGCCTTGACTATGTGAATGTTCGTTT
AGGAACAGAATTAACTTTTGCTGATATTCAAAGGATTTTTGACCAACTTGGATTTGGTCTAACAGGAGATGAAACAAGCT
TCACGGTAGCTGTTCCTCGGCGTCGTTGGGATGTTAGCATCCCAGCTGACTTGGTGGAAGAAATTGCGCGTATCTATGGT
TATGATAAGTTGCCGACAACCTTACCAGAGGCAGGGGGAACGGCTGCAGAATTAACGCCAACACAGGCTCTTCGTCGTAA
AGTCCGTGGTTTAGCGGAAGGATTGGGCTTGACTGAAATCATTTCGTATGCCTTGACAACACCAGAGAAAGCTGTTGAGT
TTGCAGTGGCACCAAGTCACCTAACAGAACTCATGTGGCCAATGTCTGTGGAACGTTCAGCGCTTCGTCAAAATATGATT
TCAGGGATGCTAGATACGGTTGCCTATAATGTGGCTCGTAAACAAAGTAACTTGGCTCTTTATGAAATTGGAAAAATCTT
TGAACAAGAAGCTAATCCAAAAGAAAACCTTCCTAATGAAGTGAACCATTTTGCTTTTGCTATTTGTGGCTTAGTGGCAC
AAAAAGATTTCCAAACCCAAGCTCAGGCAGTGGATTTTTACCATGCTAAAGGTATCTTGGATACTTTATTTGCAAACCTT
AACCTCAAGGTTCAATATGTGCCAACCAAAGACCTAGCAAACATGCACCCAGGACGGACAGCGCTTATCCTATTAGATGA
GCAAGTGATTGGATTTGTTGGTCAAGTTCATCCAGGAACAGCAAAGGCTTATAGTATTCCAGAAACCTATGTGGCAGAAT
TGGATATGGCTGCTTTAGAAGCAGCGTTGTCAAGTGATCAAACTTTTGTGGAGATTACCAAATTCCCTGCTATGACACGT
GATGTTGCCTTGTTACTTGACCGTGAAGTGAGTCATCAGGCCATTGTAACAGCTATTGAATCAGCAGGTGTAAAACGCTT
GACTAAGATTAAGCTCTTTGACGTGTATGAAGGAGTAACTATTCAGGCTGGCAAAAAATCAATGGCTTATAGCCTTAATT
TCCAAAATCCAAATGACAATTTAACGGATGAAGAAGTTGCTAAATACATGGAGAAAATCACCAAAGCATTGACAGAACAA
GTCGGTGCTGAAGTACGCTAA

Upstream 100 bases:

>100_bases
TCCCTCTCGCTTCAACGTCATAAGGGTTTTGACTTGGAACTTAAAATACGAAAGGAAATGACTCAAATCACGGCTTGAGA
GCCTTCTCTAGCCGAGTGAT

Downstream 100 bases:

>100_bases
GAAAAAAACTGGGCCTCTAAGGCTCCGTTTTTTTCTGTTATAATAGAGGAAAAAAGAACTCCAGTTCAAATGATTGGAGA
AAAACATCAGAAGGTGGAGG

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS [H]

Number of amino acids: Translated: 806; Mature: 805

Protein sequence:

>806_residues
MGTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSKLVVGHVLSCEDVPETHLHLCQVDTGDETPRQ
IVCGAPNVKAGIKVIVAVPGARIADNYKIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKY
LDLDDHIIGLSITPNRADALSMRGVAHEVAAIYGKSVSFPPKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPS
PQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADK
PVALAGVMGGQATEIDANSQTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVL
SGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFTVAVPRRRWDVSIPADLVEEIARIYG
YDKLPTTLPEAGGTAAELTPTQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMI
SGMLDTVAYNVARKQSNLALYEIGKIFEQEANPKENLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANL
NLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALEAALSSDQTFVEITKFPAMTR
DVALLLDREVSHQAIVTAIESAGVKRLTKIKLFDVYEGVTIQAGKKSMAYSLNFQNPNDNLTDEEVAKYMEKITKALTEQ
VGAEVR

Sequences:

>Translated_806_residues
MGTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSKLVVGHVLSCEDVPETHLHLCQVDTGDETPRQ
IVCGAPNVKAGIKVIVAVPGARIADNYKIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKY
LDLDDHIIGLSITPNRADALSMRGVAHEVAAIYGKSVSFPPKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPS
PQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADK
PVALAGVMGGQATEIDANSQTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVL
SGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFTVAVPRRRWDVSIPADLVEEIARIYG
YDKLPTTLPEAGGTAAELTPTQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMI
SGMLDTVAYNVARKQSNLALYEIGKIFEQEANPKENLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANL
NLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALEAALSSDQTFVEITKFPAMTR
DVALLLDREVSHQAIVTAIESAGVKRLTKIKLFDVYEGVTIQAGKKSMAYSLNFQNPNDNLTDEEVAKYMEKITKALTEQ
VGAEVR
>Mature_805_residues
GTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSKLVVGHVLSCEDVPETHLHLCQVDTGDETPRQI
VCGAPNVKAGIKVIVAVPGARIADNYKIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYL
DLDDHIIGLSITPNRADALSMRGVAHEVAAIYGKSVSFPPKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPSP
QWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKP
VALAGVMGGQATEIDANSQTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVLS
GHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFTVAVPRRRWDVSIPADLVEEIARIYGY
DKLPTTLPEAGGTAAELTPTQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMIS
GMLDTVAYNVARKQSNLALYEIGKIFEQEANPKENLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANLN
LKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALEAALSSDQTFVEITKFPAMTRD
VALLLDREVSHQAIVTAIESAGVKRLTKIKLFDVYEGVTIQAGKKSMAYSLNFQNPNDNLTDEEVAKYMEKITKALTEQV
GAEVR

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI124028525, Length=373, Percent_Identity=23.0563002680965, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1788006, Length=817, Percent_Identity=34.1493268053856, Blast_Score=401, Evalue=1e-113,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547 [H]

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 87849; Mature: 87718

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSKLVVGHVLSCED
CCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCC
VPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNYKIKKGKIRGMESL
CCCCCEEEEEECCCCCCCCEEEECCCCCCCCCEEEEECCCCEECCCCEEECCCCCCHHHH
GMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDDHIIGLSITPNRADAL
HHHHHHHHCCCCCCCCCHHHCCCCEECCCCCCCHHHHHEEECCCCCEEEEEECCCCCHHH
SMRGVAHEVAAIYGKSVSFPPKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCC
PQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVT
HHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEE
LDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANSQTVVLEVAVFDGKSIRKTSGR
ECCCCCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCEEEEEEEEECCCCHHHCCCC
LNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVLSGHVQAGQLPTEPVEVSTSL
EEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCEECCCCCCCCEEEECCC
DYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFTVAVPRRRWDVSIPADLVEEIARIYG
CEEEEEECCEECHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
YDKLPTTLPEAGGTAAELTPTQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHEEEECHHH
LTELMWPMSVERSALRQNMISGMLDTVAYNVARKQSNLALYEIGKIFEQEANPKENLPNE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCHH
VNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANLNLKVQYVPTKDLANMHPGRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCE
ALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALEAALSSDQTFVEITKFPAMTR
EEEEECHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
DVALLLDREVSHQAIVTAIESAGVKRLTKIKLFDVYEGVTIQAGKKSMAYSLNFQNPNDN
HHHHHHCCCCCHHHHHHHHHHCCHHHHHEEEEEEHCCCCEEECCCCCEEEEEEECCCCCC
LTDEEVAKYMEKITKALTEQVGAEVR
CCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSKLVVGHVLSCED
CCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCC
VPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNYKIKKGKIRGMESL
CCCCCEEEEEECCCCCCCCEEEECCCCCCCCCEEEEECCCCEECCCCEEECCCCCCHHHH
GMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDDHIIGLSITPNRADAL
HHHHHHHHCCCCCCCCCHHHCCCCEECCCCCCCHHHHHEEECCCCCEEEEEECCCCCHHH
SMRGVAHEVAAIYGKSVSFPPKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCC
PQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVT
HHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEE
LDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANSQTVVLEVAVFDGKSIRKTSGR
ECCCCCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCEEEEEEEEECCCCHHHCCCC
LNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVLSGHVQAGQLPTEPVEVSTSL
EEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCEECCCCCCCCEEEECCC
DYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFTVAVPRRRWDVSIPADLVEEIARIYG
CEEEEEECCEECHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
YDKLPTTLPEAGGTAAELTPTQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHEEEECHHH
LTELMWPMSVERSALRQNMISGMLDTVAYNVARKQSNLALYEIGKIFEQEANPKENLPNE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCHH
VNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANLNLKVQYVPTKDLANMHPGRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCE
ALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALEAALSSDQTFVEITKFPAMTR
EEEEECHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
DVALLLDREVSHQAIVTAIESAGVKRLTKIKLFDVYEGVTIQAGKKSMAYSLNFQNPNDN
HHHHHHCCCCCHHHHHHHHHHCCHHHHHEEEEEEHCCCCEEECCCCCEEEEEEECCCCCC
LTDEEVAKYMEKITKALTEQVGAEVR
CCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA