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The map label for this gene is 94994049

Identifier: 94994049

GI number: 94994049

Start: 626409

End: 629141

Strand: Direct

Name: 94994049

Synonym: MGAS10750_Spy0653

Alternate gene names: NA

Gene position: 626409-629141 (Clockwise)

Preceding gene: 94994048

Following gene: 94994050

Centisome position: 32.34

GC content: 37.94

Gene sequence:

>2733_bases
ATGATTAACAAGAAATATATAATACCTGTTTCATTGTTGACACTAGCTATTACGCTTACTAGTGTTGAAGAAGTTACTTC
ACGTCAAAATTTGACTTATGCCAATGAAATCGTAACACAAAGGCCAAAGAGAGAATCTGTTATTAGTGATAAATCGAATT
TTCCCGTCATATCACCTTACCTAGCAAGTGTGGATTTTGGTGAGAGAAAAACACCTTTGCCAACACCTGATAAAGGAGTA
AAAGTAACTACTGAACAGTCTATTGCTCAAGTAAGAAAGGGGCCTGAAGAAAGAACCTATACTGTTACTGGCAAGATTAC
GAGTGTGATCAATGGCTGGGGAGGCTATGGCTTTTATATTCAAGATAGTGAAGGTATTGGACTTTATGTTTATCCTCAAA
AAGATTTAGGATACAGTAAGGGAGATATTGTTCAATTAACAGGTACACTTACTCGCTTTAAAGGTGATTTACAACTCCAA
CAGGTGACTGCACACAAAAAGTTAGAGTTATCTTTTCCGACTTCTGTTAAAGAAGCAGTAATATCAGAATTAGAAACAAC
AACACCCTCAACATTAGTTAAGTTATCTCACGTGACAGTTGGAGAATTATCAACTGATCAATATAACAACACATCTTTCC
TTGTAAGGGATGATAGTGGTAAAAGTATAGTTGTTCATATAGATCATCGTACAGGGGTTAAAGGGGCTGATGTTGTTACT
AAAATAAGTCAGGGTGATTTGATTAACCTCACAGCCATATTGTCTATTGTTGATGGTCAGTTACAATTAAGACCGTTTTC
TCTTGAACAATTGGATGTGGTTAAAAAGGTTACAAGCTCAAATAGTGATGCTTCATCTCGTAATATTGTGAAAATAGGCG
AGATTCAAGGAGCTAGTCATACGTCGCCACTTCTCAAAAAAGCGGTCACCGTAGAACAGGTTGTTGTCACTTATTTAGAC
GATTCCACTCATTTTTATGTTCAAGATCTTAATGGTGATGGTGATTTAGCGACTTCAGATGGTATTCGTGTTTTTGCTAA
AAACGCTAAGGTTCAAGTCGGCGATGTTTTGACCATTTCAGGTGAAGTGGAAGAATTCTTTGGTCGTGGTTATGAGGAAC
GTAAGCAGACTGACCTTACCATCACCCAAATTGTGGCTAAAGCAGTGACCAAAACAGGGACAGCTCAAGTTCCATCACCG
CTTGTTTTAGGGAAAGATCGTATCGCGCCAGCCAATATTATTGATAATGATGGCTTGCGTGTGTTTGATCCAGAAGAAGA
CGCTATTGATTATTGGGAATCAATGGAAGGCATGTTAGTGGCGGTTGATGATGCTAAAATCCTTGGTCCAATGAAAAATA
AAGAAATTTATGTCTTACCTGGCTCTAGTACAAGACCGTTAAATAATTCAGGTGGAGTATTACTTCCAGCTAATTCTTAT
AACACAGATGTGATTCCTGTTCTTTTCAAAAAAGGCAAACAAATTATTAAAGCAGGAGACTCTTACAAAGGAAGATTAGC
TGGGCCAGTATCTTATAGCTATGGTAATTACAAGGTCTTTGTTGATGACAGCAAAAACATGCCAAGTTTAATGGATGGTC
ATCTAAAACCTGAAAAAACAAACTTGCAAAAAGACCTTAGCAAGTTAAGCATTGCTTCTTACAATATTGAAAACTTCTCA
GCCAATCCTTCTTCAACTAAAGATGAGAAGGTCAAACGGATTGCCGAATCCTTTATTCATGATCTGAATGCTCCAGACAT
TATTGGATTAATTGAAGTCCAAGATAATAATGGGCCGACTGATGATGGGACAACGGATGCGACACAAAGCGCACAACGCC
TCATTGATGCTATTAAAAAACTAGGTGGCCCAACTTATCGTTATGCTGATATTGCTCCAGAAAATAATGTTGACGGAGGT
CAACCAGGTGGTAATATTCGAACAGGATTCCTTTATCAACCAGAGCGCGTCAGCCTTTCTGATAAGCCAAAAGGCGGTGC
TCGTGATGCTCTAACTTGGGTTAATGGAGAATTAAACCTTAGTGTTGGTCGAATTGATCCAACTAACGCCGCTTGGAAAG
ATGTTCGTAAATCACTAGCAGCAGAATTTATCTTCCAAGGTCGTAAAGTCGTTGTTGTTGCAAATCATTTGAACTCTAAG
CGTGGGGATAATGCTCTTTATGGTCGTGTGCAACCAGTCACTTTTAAATCTGAGCAAAGACGTCACGTCTTGGCTAATAT
GCTAGCACAATTTGCGAAAGAAGGGGCAAAACACCAAGCTAATATTGTGATGCTAGGTGACTTTAATGATTTTGAATTCA
CAAAGACGATTCAATTAATCGAAGAAGGTGATATGGTTAACTTGGTGAGCCGACATGATATTTCAGATCGGTATTCTTAT
TTTCACCAAGGCAATAATCAGACCCTTGATAATATATTAGTTTCACGCCATTTACTTGATCACTACGAATTTGACATGGT
TCATGTGAATTCCCCATTTATGGAAGCGCACGGACGCGCATCAGATCATGATCCATTGTTACTTCAATTATCATTTTCTA
AAGAAAATGATAAGGCAGAGTCTTCTAAACAAAGTGTAAAAGCTAAAAAAACTTCAAAAGGAAAACTGTTGCCAAAAACA
GGAGATAGTCTTGTTTATGTGATAACGCTACTAGGAACGGCTAGTTTATTAGTGCCTATTTTATTATTGACTAAAGGCAA
AAAGGAATCATAG

Upstream 100 bases:

>100_bases
AACAGAAAGTGTATCCCAATTCATAGTCTCAGGTGGAGGTTAATATTCAAAAATAAAATCTTGTTGTTGTCTTAAACTAA
TCACATTAAAAGGAGATATC

Downstream 100 bases:

>100_bases
CGATTTGAAGAATTGGAGTTCATAAAGAGTCGTTAAAGGCTTGATATACTTACGTTAGACCTTAAGCTAAAATGGATGAC
TATATAAAAACTAAGATTGA

Product: endonuclease/exonuclease/phosphatase family protein

Products: NA

Alternate protein names: Large Secreted Protein; Extracellular Nuclease; Endonuclease/Exonuclease/Phosphatase Family Protein; Endonuclease/Exonuclease/Phosphatase Family; Endonuclease I; 5-Nucleotidase Domain Protein; Alkaline Phosphatase; 5-Nucleotidase Domain-Containing Protein; 5-Nucleotidase/2' 3'-Cyclic Phosphodiesterase; DNA Nuclease; Extracellular Nuclease-Like Protein; Hydrolase; LPXTG Cell Wall Surface Protein; Endonuclease YhcR

Number of amino acids: Translated: 910; Mature: 910

Protein sequence:

>910_residues
MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGV
KVTTEQSIAQVRKGPEERTYTVTGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVT
KISQGDLINLTAILSIVDGQLQLRPFSLEQLDVVKKVTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLD
DSTHFYVQDLNGDGDLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSP
LVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGPMKNKEIYVLPGSSTRPLNNSGGVLLPANSY
NTDVIPVLFKKGKQIIKAGDSYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFS
ANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGPTYRYADIAPENNVDGG
QPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSK
RGDNALYGRVQPVTFKSEQRRHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRYSY
FHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKENDKAESSKQSVKAKKTSKGKLLPKT
GDSLVYVITLLGTASLLVPILLLTKGKKES

Sequences:

>Translated_910_residues
MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGV
KVTTEQSIAQVRKGPEERTYTVTGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVT
KISQGDLINLTAILSIVDGQLQLRPFSLEQLDVVKKVTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLD
DSTHFYVQDLNGDGDLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSP
LVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGPMKNKEIYVLPGSSTRPLNNSGGVLLPANSY
NTDVIPVLFKKGKQIIKAGDSYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFS
ANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGPTYRYADIAPENNVDGG
QPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSK
RGDNALYGRVQPVTFKSEQRRHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRYSY
FHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKENDKAESSKQSVKAKKTSKGKLLPKT
GDSLVYVITLLGTASLLVPILLLTKGKKES
>Mature_910_residues
MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGV
KVTTEQSIAQVRKGPEERTYTVTGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVT
KISQGDLINLTAILSIVDGQLQLRPFSLEQLDVVKKVTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLD
DSTHFYVQDLNGDGDLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSP
LVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGPMKNKEIYVLPGSSTRPLNNSGGVLLPANSY
NTDVIPVLFKKGKQIIKAGDSYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFS
ANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGPTYRYADIAPENNVDGG
QPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSK
RGDNALYGRVQPVTFKSEQRRHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRYSY
FHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKENDKAESSKQSVKAKKTSKGKLLPKT
GDSLVYVITLLGTASLLVPILLLTKGKKES

Specific function: Unknown

COG id: COG2374

COG function: function code R; Predicted extracellular nuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 99881; Mature: 99881

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISDKSNFPVISPY
CCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCCCCCCEECHH
LASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTYTVTGKITSVINGWGGYGFYI
HHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEEEEEHHCCCCCEEEEE
QDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQQVTAHKKLELSFPTSVKEAV
ECCCCCEEEEEECCCCCCCCCCEEEEEEEHHHHCCCCEEEEECCCCEEEEECCCHHHHHH
ISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVT
HHHHHCCCCHHEEEEECEEECCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHE
KISQGDLINLTAILSIVDGQLQLRPFSLEQLDVVKKVTSSNSDASSRNIVKIGEIQGASH
EECCCCEEEHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
TSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDGDLATSDGIRVFAKNAKVQVGDVLTIS
CCHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCCEECCCCEEEEEECCEEEECEEEEEC
GEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSPLVLGKDRIAPANIIDNDGLR
CCHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEECCCCCE
VFDPEEDAIDYWESMEGMLVAVDDAKILGPMKNKEIYVLPGSSTRPLNNSGGVLLPANSY
EECCCHHHHHHHHCCCCEEEEECCCCEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCC
NTDVIPVLFKKGKQIIKAGDSYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKT
CCCCHHHHHHCCHHHHHCCCCCCCEECCCEEECCCCEEEEEECCCCCCHHHCCCCCCCHH
NLQKDLSKLSIASYNIENFSANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPT
HHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
DDGTTDATQSAQRLIDAIKKLGGPTYRYADIAPENNVDGGQPGGNIRTGFLYQPERVSLS
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECEEECCCCCCCC
DKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSK
CCCCCCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
RGDNALYGRVQPVTFKSEQRRHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLI
CCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHH
EEGDMVNLVSRHDISDRYSYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRA
HCCCEEEEHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCC
SDHDPLLLQLSFSKENDKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPI
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
LLLTKGKKES
HHHCCCCCCC
>Mature Secondary Structure
MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISDKSNFPVISPY
CCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCCCCCCEECHH
LASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTYTVTGKITSVINGWGGYGFYI
HHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEEEEEHHCCCCCEEEEE
QDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQQVTAHKKLELSFPTSVKEAV
ECCCCCEEEEEECCCCCCCCCCEEEEEEEHHHHCCCCEEEEECCCCEEEEECCCHHHHHH
ISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVT
HHHHHCCCCHHEEEEECEEECCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHE
KISQGDLINLTAILSIVDGQLQLRPFSLEQLDVVKKVTSSNSDASSRNIVKIGEIQGASH
EECCCCEEEHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
TSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDGDLATSDGIRVFAKNAKVQVGDVLTIS
CCHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCCEECCCCEEEEEECCEEEECEEEEEC
GEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSPLVLGKDRIAPANIIDNDGLR
CCHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEECCCCCE
VFDPEEDAIDYWESMEGMLVAVDDAKILGPMKNKEIYVLPGSSTRPLNNSGGVLLPANSY
EECCCHHHHHHHHCCCCEEEEECCCCEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCC
NTDVIPVLFKKGKQIIKAGDSYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKT
CCCCHHHHHHCCHHHHHCCCCCCCEECCCEEECCCCEEEEEECCCCCCHHHCCCCCCCHH
NLQKDLSKLSIASYNIENFSANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPT
HHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
DDGTTDATQSAQRLIDAIKKLGGPTYRYADIAPENNVDGGQPGGNIRTGFLYQPERVSLS
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECEEECCCCCCCC
DKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSK
CCCCCCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
RGDNALYGRVQPVTFKSEQRRHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLI
CCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHH
EEGDMVNLVSRHDISDRYSYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRA
HCCCEEEEHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCC
SDHDPLLLQLSFSKENDKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPI
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
LLLTKGKKES
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA