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The map label for this gene is eriC [C]

Identifier: 94994029

GI number: 94994029

Start: 599273

End: 600547

Strand: Direct

Name: eriC [C]

Synonym: MGAS10750_Spy0633

Alternate gene names: 94994029

Gene position: 599273-600547 (Clockwise)

Preceding gene: 94994028

Following gene: 94994030

Centisome position: 30.94

GC content: 42.12

Gene sequence:

>1275_bases
GTGGTGACATTAATGATTAAATCAATTGCAACACTGCCTAAACCCTCCTTAAAAGAAGCGTTAGGACTAATAGGTTTGGC
GCTTCCCATAGGGGTCGCGGTTGGAGTGGTTGATGTGATTTTTGGTAAAGGGCTTTTGTTTCTTTCCGAGTATCGCGATC
ACCACCTTTTCTTGCTTCTTCCTTTTCTTGCCCTAGCAGGTCTTGTTATCGTTTTTCTTTACGATAAGTTAGGCAAAGAG
GTTCGTCAAGGGATGGGATTGGTTTTTCAGGTAGGGCATGGTCAAAAAGATCAGATTCCTCCTATTCTCATTCCTCTTAT
TTTGTTCTCGACTTGGGTAACCCACTTATTTGGAGCGAGTGCGGGTCGAGAAGGGGTAGCCGTTCAAATAGGAGCTACCA
TCTCTCATTATTGTCAGAGATTTGTGACTAGTCAAGAAGCCGCACGACACCTTTTAATTATGGGGATGGCAGCCGGTTTT
GCAGGACTTTTTCAAACGCCGATTGCTGCTGTCGTATTTGCCCTCGAGGTTTTATTGGTAGGAACGCTTCGCTACTGCGC
TTTATTACCTTCCTTAGTTGCTGCTTGCGTGGCTTCTTGGACCTCTCATTCTTTGGGATTAGAGAAATTTACGATTGTTC
TTGAAGAAACATTGACCATAACTCCCTTAACCTTAGTTAAATTAATTGGGTTAGGTCTTATTTTTGGTCTGGTGGGAAAT
AGTTTTGCCTGTTTACTTGGCTGGTTTAAACCTTACCTGAGTCAAAAGCTACCAAATCCTTATCTCAGGATTGCTTTCAT
TGGTGTTTTGTTATCTATCTGTTTGATGATTGGTCACGTTGGAAGATATAGTGGTCTAGGGACTCATTTGCTTGCGGCAG
CTTTTTCTGGCCAAACTATCCTAACTTACGACTGGCTTTTAAAAATGATCGTGACGGTGATTAGCTTATCTGCAGGCTTT
CAAGGTGGTGAAGTGACGCCTCTATTTGCTATTGGAGCTTCTTTAGGTATCGTTTTGGCCCCTTACTTAGGTCTTCCTGT
ACTGTTGGTTGCTGCACTTGGTTATGTCACGGTATTTGGAAGTGCAACAAATACCTTTTGGGCCCCTATCTTTATTGGGA
TAGAGGTCTTTGGTCCAGAGAATGCCCTAGCATATTTTGTCACCTCGGCTGCAGCCTATATGATTAGTCACAGACATTCC
ATTTACAGTTATCAAAAAGTAGTCATGATCAATTTAAAAGACATGACGGTAAATCAGATGGATTTAAAAAAATAG

Upstream 100 bases:

>100_bases
TCTTATCTCGTTAAAGACCAAGCATTTGAGCCAGCTATCCATGAGACGTTTAAAACCATTATGTCTCTTTCACGGCAGTA
TCAAACGCAACACTTAACAG

Downstream 100 bases:

>100_bases
CTTTACAATAAAGAAGCTTTTTGTTAGAATAAATCTCGTGTGTAATGGACACACGAAAATTACGGCTAATCCGCTAAGAC
AAGTACTTAAGATTAGTAAG

Product: chloride channel protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MVTLMIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFLSEYRDHHLFLLLPFLALAGLVIVFLYDKLGKE
VRQGMGLVFQVGHGQKDQIPPILIPLILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGF
AGLFQTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITPLTLVKLIGLGLIFGLVGN
SFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHVGRYSGLGTHLLAAAFSGQTILTYDWLLKMIVTVISLSAGF
QGGEVTPLFAIGASLGIVLAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMISHRHS
IYSYQKVVMINLKDMTVNQMDLKK

Sequences:

>Translated_424_residues
MVTLMIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFLSEYRDHHLFLLLPFLALAGLVIVFLYDKLGKE
VRQGMGLVFQVGHGQKDQIPPILIPLILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGF
AGLFQTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITPLTLVKLIGLGLIFGLVGN
SFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHVGRYSGLGTHLLAAAFSGQTILTYDWLLKMIVTVISLSAGF
QGGEVTPLFAIGASLGIVLAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMISHRHS
IYSYQKVVMINLKDMTVNQMDLKK
>Mature_424_residues
MVTLMIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFLSEYRDHHLFLLLPFLALAGLVIVFLYDKLGKE
VRQGMGLVFQVGHGQKDQIPPILIPLILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGF
AGLFQTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITPLTLVKLIGLGLIFGLVGN
SFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHVGRYSGLGTHLLAAAFSGQTILTYDWLLKMIVTVISLSAGF
QGGEVTPLFAIGASLGIVLAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMISHRHS
IYSYQKVVMINLKDMTVNQMDLKK

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 45568; Mature: 45568

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLMIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFLSEYRDHHLFLLL
CCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
PFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPLILFSTWVTHLFGAS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
AGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLFQTPIAAVVFALEVLLV
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITPLTLVKLIGLGLIFGLVGN
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
SFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHVGRYSGLGTHLLAAAFSGQTI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEE
LTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIVLAPYLGLPVLLVAALGYVTVFG
EHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMISHRHSIYSYQKVVMINLKDMTVNQM
CCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHH
DLKK
CCCC
>Mature Secondary Structure
MVTLMIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFLSEYRDHHLFLLL
CCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
PFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPLILFSTWVTHLFGAS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
AGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLFQTPIAAVVFALEVLLV
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITPLTLVKLIGLGLIFGLVGN
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
SFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHVGRYSGLGTHLLAAAFSGQTI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEE
LTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIVLAPYLGLPVLLVAALGYVTVFG
EHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMISHRHSIYSYQKVVMINLKDMTVNQM
CCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHH
DLKK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]