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The map label for this gene is clpP [H]

Identifier: 94993998

GI number: 94993998

Start: 570595

End: 571260

Strand: Direct

Name: clpP [H]

Synonym: MGAS10750_Spy0602

Alternate gene names: 94993998

Gene position: 570595-571260 (Clockwise)

Preceding gene: 94993997

Following gene: 94993999

Centisome position: 29.46

GC content: 38.89

Gene sequence:

>666_bases
ATGCCAAAGAGGATAAATCTTAAAGGCCCACTTATTGCAAATAATTCGCAAGAAGTTTATGACTACTATGGAATGGAAGC
GACTAGTGCCAAAAGCATTATTAACCAATTGCCAGAAGATAGCAGTGATATTATTTTGGAAGTTAATTCAAACGGTGGTC
TTGTTACAGTAGGGAGTGAAGTCTATACCGCTTTGCGAAATTACAAAGGAAAAGTAACTGCAGAAATTACTGGCATGGCT
GCAAGTGCAGCATCCGTTGCAGTTATGGGAGCAGATAAAGTTGTCATGAGTCCAACAGCACAGATGATGGTACACAAGGC
ATTGTTTAATTGGGTAGCTGGTAATAGCGATGACTTAGATAAAGCTTCTAATGCTTTGAAATCAAGTGATAAAGCTATCG
TGAATGCCTATGTCGCAAAGACAGGGTTATCGGAAGATGAAATCATGAATTTAATGCGGAATGAAACGTTTATGTCTGCT
CAAGACGCTGTTGAAAAAGGTTTTGCTGATGAAGTGATGTCTTTTGAAGCGGTGGCGAGTATCGATAACCAAATGTTGCC
ACAAGCTGTTATTGACGACTATTACGCAAACAGAAGTAAGCGCAAGCAAGAGATTAGCAACATGTTGCTAGAAATTGAAA
AAGAAGAAATTTTACAAGGGCTATAA

Upstream 100 bases:

>100_bases
AATATGGATAGGTACCAATCGAGTCTAAACTATGTCTTTTTGGATAAAAAAGAAGAATATCAGGACAAGGTTGGTATCAA
AGGGAAAGGAGGTGAGGTAA

Downstream 100 bases:

>100_bases
GCTCTTTTTTTATTGGAGGAATTTATGTTCGAAGAAAAAATCAAAGAAATTAAAGCGACTATCGCTAGTTTAAACCAAGC
GATTGCTACTAAAACAGCCG

Product: ATP-dependent endopeptidase clp proteolytic subunit clpP

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MPKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDIILEVNSNGGLVTVGSEVYTALRNYKGKVTAEITGMA
ASAASVAVMGADKVVMSPTAQMMVHKALFNWVAGNSDDLDKASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSA
QDAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEILQGL

Sequences:

>Translated_221_residues
MPKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDIILEVNSNGGLVTVGSEVYTALRNYKGKVTAEITGMA
ASAASVAVMGADKVVMSPTAQMMVHKALFNWVAGNSDDLDKASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSA
QDAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEILQGL
>Mature_220_residues
PKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDIILEVNSNGGLVTVGSEVYTALRNYKGKVTAEITGMAA
SAASVAVMGADKVVMSPTAQMMVHKALFNWVAGNSDDLDKASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSAQ
DAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEILQGL

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24050; Mature: 23918

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDIILEVNSNGGLVTVGSE
CCCCCCCCCCEEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECHH
VYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQMMVHKALFNWVAGNSDDLD
HHHHHHCCCCCEEEEEECHHHHHHHEEEECCCCEEECHHHHHHHHHHHHHHHCCCCCCHH
KASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSAQDAVEKGFADEVMSFEAVAS
HHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEILQGL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure 
PKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDIILEVNSNGGLVTVGSE
CCCCCCCCCEEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECHH
VYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQMMVHKALFNWVAGNSDDLD
HHHHHHCCCCCEEEEEECHHHHHHHEEEECCCCEEECHHHHHHHHHHHHHHHCCCCCCHH
KASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSAQDAVEKGFADEVMSFEAVAS
HHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEILQGL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]