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The map label for this gene is aspC [H]

Identifier: 94993951

GI number: 94993951

Start: 540088

End: 541281

Strand: Direct

Name: aspC [H]

Synonym: MGAS10750_Spy0555

Alternate gene names: 94993951

Gene position: 540088-541281 (Clockwise)

Preceding gene: 94993950

Following gene: 94993952

Centisome position: 27.88

GC content: 42.21

Gene sequence:

>1194_bases
ATGCCCAAACTATCAAAGCGAGTTTTAGAAATGAAAGAGAGTGTTACTCTGGCTGCAGGTGCTAGAGCTAAGGCTTTGAA
AGCGCAGGGCCGTGATGTACTGAATTTAACTTTAGGAGAACCAGATTTTTTTACACCTAAGCACATTCAAGACAAGGCGA
TTGAATCTATTCAAAATGGTACGGCTAGCTTTTATACAAATGCTTCTGGGCTTCCAGAATTAAAAGCTGCGATTGCCACA
TACCTGAAAAATCAGTATGGGTATCACTTGTCTCCTGATCAGATTGTGGCAGGAACAGGTGCCAAGTTCATCCTTTATGC
CTTTTTTATGGCTGTTTTAAATCCTGGTGACCAAGTTCTCATTCCAACACCATATTGGGTATCTTATTCTGACCAAGTAA
AAATGGCAGAAGGTCAGCCGATCTTCGTTCAAGGACTAGAAGAAAATCAATTCAAGGTAACTGTTGACCAGCTGGAAAGA
GCAAGGACAAGTAAGACTAAAGTTGTCCTTATCAATTCCCCTTCCAATCCAACAGGTATGATTTATGGTGCTGAGGAATT
AAGGGCCATTGGAGAATGGGCGGTGCACAACGATATTCTTATTCTGGCAGATGATATTTACGGGTCCTTAGTCTATAACG
GCAATCAGTTTGTTCCTATTTCAACACTCTCAGAAGCGATTCGTCGTCAAACCATTACGGTCAATGGCGTGGCTAAAAGT
TATGCCATGACAGGCTGGCGGGTTGGTTTTGCAGCAGGTGAACCAGAGATCATTTCGGCAATGAGTAAGATCATCGGGCA
GACTACCTCTAACCTGACAACCGTTTCACAATATGCTGCTATCGAGGCTTTCTGTGGTAGTCAGTCATCACTTGAAGAGA
TGCGATTAGCGTTTGAAGAGCGCCTTAATATCATTTATCCATTGTTGTGTCAGGTCCCTGGGTTTGAGGTTGTTAAACCA
CAAGGAGCTTTTTACTTCTTTCCAAACGTTAAGAAAGCCATGGAAATGACAGGTTTTTCCGATGTGACAAGCTTTGCTAA
TGCTATTTTAGAGGAAGTCGGATTAGCTGTTGTGAGTGGAGCAGGCTTTGGCGCACCGGAAAATGTTCGTCTGAGTTATG
CTACAGATATCGAAACCCTTAAAGAAGCTGTTCGTAGACTGCATGTCTTTATGGAAAGTAATGAAATTAATTAA

Upstream 100 bases:

>100_bases
AGTAGCGAGTATTGGTAAAACTGAAACCGTAGATTATGAAAAAATGATCTGTTGATCATTAATTAATCTGAAGATAAGAA
GTCGATAAAAAGGAGATACG

Downstream 100 bases:

>100_bases
ATAAAAATAGAGAGAAACTTATGTCAAAAAAACTTATTTCAATTGTTGATGTTAAAGATTATGTTGGTCAAGAAGTTACT
ATTGGTGCTTGGGTTGCTAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNGTASFYTNASGLPELKAAIAT
YLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEERLNIIYPLLCQVPGFEVVKP
QGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN

Sequences:

>Translated_397_residues
MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNGTASFYTNASGLPELKAAIAT
YLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEERLNIIYPLLCQVPGFEVVKP
QGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN
>Mature_396_residues
PKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATY
LKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLERA
RTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKSY
AMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEERLNIIYPLLCQVPGFEVVKPQ
GAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=26.0545905707196, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=26.0545905707196, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=28.125, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=28.125, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=23.6979166666667, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI169881281, Length=397, Percent_Identity=23.6775818639798, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI19263340, Length=395, Percent_Identity=23.0379746835443, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI215599424, Length=395, Percent_Identity=23.0379746835443, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4885351, Length=383, Percent_Identity=24.2819843342037, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1788722, Length=373, Percent_Identity=26.0053619302949, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=27.012987012987, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=24.3169398907104, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=27.4151436031332, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=426, Percent_Identity=26.9953051643192, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=294, Percent_Identity=29.9319727891156, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=294, Percent_Identity=29.9319727891156, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71981209, Length=374, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=395, Percent_Identity=24.8101265822785, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=344, Percent_Identity=23.546511627907, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=345, Percent_Identity=23.1884057971014, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28573069, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646114, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28573067, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28573065, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.9583333333333, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45551451, Length=408, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641770, Length=408, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641760, Length=408, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641768, Length=408, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641766, Length=408, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641764, Length=408, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43473; Mature: 43342

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNG
CCCHHHHHHHHHHHEEEECCCHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCC
TASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVL
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEE
IPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLERARTSKTKVVLINSPSNPTGM
ECCCCEECCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCEE
IYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
EECHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEHHHHHHHHHHCEEEEECHHHH
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEE
HHHCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLNIIYPLLCQVPGFEVVKPQGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSG
HHHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEC
AGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNG
CCHHHHHHHHHHHEEEECCCHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCC
TASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVL
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEE
IPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLERARTSKTKVVLINSPSNPTGM
ECCCCEECCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCEE
IYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
EECHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEHHHHHHHHHHCEEEEECHHHH
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEE
HHHCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLNIIYPLLCQVPGFEVVKPQGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSG
HHHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEC
AGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]